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Beneficial effects of date palm fruits on neurodegenerative diseases

Neural Regeneration Research 2016年第7期11卷 1071-1072页

作者： Musthafa Mohamed Essa mohammed akbar mohammed Abdul Sattar Khan Department of Food Science and Nutrition College of Agriculture and Marine SciencesSultan Qaboos University Ageing and Dementia Research Group Sultan Qaboos University Section of Molecular Pharmacology and Toxicology Laboratory of Membrane Biochemistry and BiophysicsNational Institute on Alcohol Abuse and AlcoholismNational Institutes of Health Department of Anesthesia Critical Care and Pain MedicineShriners Hospitals for Children~?Massachusetts General Hospital and Harvard Medical School

Date palm tree（Phoenix dactylifera L.）is an important crop,which is cultivated in many countries extending from North Africa to the Middle East,including many of the GCC（Gulf Cooperation Council）Countries（Allaith... 详细信息

关键词： fruits Phoenix climatic cultivated Africa neuronal Middle amyloid poorly occlusion

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Neuroprotective effects of berry fruits on neurodegenerative diseases

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Neural Regeneration Research 2014年第16期9卷 1557-1566页

作者： Selvaraju Subash Musthafa Mohamed Essa Samir Al-Adawi Mushtaq A.Memon Thamilarasan Manivasagam mohammed akbar Department of Food Science and Nutrition College of Agricultural and Marine Sciences Sultan Qaboos University Muscat Sultanate of Oman Ageing and Dementia Research Group Sultan Qaboos University College of Medicine and Health Sciences Sultan Qaboos University College of Veterinary Medicine Washington State University Department of Biochemistry and Biotechnology Annamalai University Section of Molecular Pharmacology and Toxicology Laboratory of Membrane Biochemistry and Biophysics National Institute on Alcohol Abuse and Alcoholism National Institutes of Health

Recent clinical research has demonstrated that berry fruits can prevent age-related neurodegenerative diseases and improve motor and cognitive functions. The berry fruits are also capable of modulating signaling pathways involved in inflammation, cell survival, neurotransmission and enhancing neuroplasticity. The neuroprotective effects of berry fruits on neurodegenerative diseases are related to phytochemicals such as anthocyanin, caffeic acid, catechin, quercetin, kaempferol and tannin. In this review, we made an attempt to clearly describe the beneficial effects of various types of berries as promising neuroprotective agents.

关键词： nerve regeneration berry fruit neurodegenerative disease neuroprotection Alzheimer'sdisease Parkinson's disease review neural regeneration

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Sepsis during short bowel syndrome hospitalizations:Identifying trends,disparities,and clinical outcomes in the United States

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World Journal of Gastrointestinal Pathophysiology 2024年第1期15卷 26-36页

作者： Dushyant Singh Dahiya Jennifer Wachala Shantanu Solanki Dhanshree Solanki Asim Kichloo Samantha Holcomb Uvesh Mansuri Khwaja Saad Haq Hassam Ali Manesh Kumar Gangwani Yash R Shah Teresa Varghese Hafiz Muzaffar akbar Khan Simon Peter Horslen Thomas D Schiano Syed-mohammed Jafri Division of Gastroenterology Hepatology&MotilityThe University of Kansas School of MedicineKansas CityKS 66160United States Department of Internal Medicine Samaritan Medical CenterWatertownNY 13601United States Division of Gastroenterology Hepatology&Nutrition The University of Texas MD Anderson Cancer CenterHoustonTX 77030United States Department of Medicine Institute for Foreign Medical Graduate EducationHoustonTX 77030United States Department of Internal Medicine MedStar Harbor HospitalBaltimoreMD 21225United States Department of Internal Medicine WellStar Spalding Regional HospitalGriffinGA 30224United States Division of Gastroenterology Hepatology and NutritionEast Carolina University/Brody School of MedicineGreenvilleNC 27858United States Department of Gastroenterology and Hepatology University of Arkansas for Medical SciencesLittle RockAR 72205United States Department of Internal Medicine Trinity Health Oakland/Wayne State UniversityPontiacMI 48341United States Division of Gastroenterology and Hepatology SUNY Upstate Medical UniversitySyracuseNY 13210United States Department of Pediatrics School of Medicine and UPMC Children’s Hospital of PittsburghUniversity of PittsburghPittsburghPA 15219United States Division of Liver Diseases Icahn School of Medicine at Mount SinaiNew YorkNY 10029United States Division of Gastroenterology and Hepatology Henry Ford HospitalDetroitMI 48202United States

BACKGROUND Short bowel syndrome(SBS)hospitalizations are often complicated with *** is a significant paucity of data on adult SBS hospitalizations in the United States and across the *** To assess trends and outcomes of SBS hospitalizations complicated by sepsis in the United *** The National Inpatient Sample was utilized to identify all adult SBS hospitalizations between *** study cohort was further divided based on the presence or absence of *** were identified,and hospitalization characteristics and clinical outcomes were *** of mortality for SBS hospitalizations complicated with sepsis were *** Of 247097 SBS hospitalizations,21.7%were complicated by *** SBS hospitalizations had a rising trend of hospitalizations from 20.8%in 2005 to 23.5%in 2014(P trend<0.0001).Compared to non-septic SBS hospitalizations,septic SBS hospitalizations had a higher proportion of males(32.8%vs 29.3%,P<0.0001),patients in the 35-49(45.9%vs 42.5%,P<0.0001)and 50-64(32.1%vs 31.1%,P<0.0001)age groups,and ethnic minorities,i.e.,Blacks(12.4%vs 11.3%,P<0.0001)and Hispanics(6.7%vs 5.5%,P<0.0001).Furthermore,septic SBS hospitalizations had a higher proportion of patients with intestinal transplantation(0.33%vs 0.22%,P<0.0001),inpatient mortality(8.5%vs 1.4%,P<0.0001),and mean length of stay(16.1 d vs 7.7 d,P<0.0001)compared to the non-sepsis cohort.A younger age,female gender,White race,and presence of comorbidities such as anemia and depression were identified to be independent predictors of inpatient mortality for septic SBS *** Septic SBS hospitalizations had a rising trend between 2005-2014 and were associated with higher inpatient mortality compared to non-septic SBS hospitalizations.

关键词： Short bowel syndrome Sepsis Outcomes Mortality Trends

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Further constituents from Rhododendron lepidotum L

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Chinese Chemical Letters 2010年第3期21卷 332-336页

作者： Mudasir Ahmad Tantry Reehana Khan Seema akbar Abdul Sami Shawl mohammed Khalid Siddiqui Drug Standardisation Research Unit Regional Research Institute of Unani Medicine(CCRUM)Naseem Bagh CampusUniversity of Kashmir Natural Product Chemistry Division Indian Institute of Integrative Medicine(CSIR) Central Council for Research in Unani Medicine(CCRUM)

A unusual flavone glycoside named Shamimarin(1) and a new compound Acetoxy-8-methyl-chromen-2H-one(2) were isolated from aerial parts of Rhododendron lepidotum *** with four known coumarins daphnin(3),daphnetin 8-O-β-D-glucopyrano-side (4),daphnetin(5) and umbelliferone(6).The structural elucidations were based on analyses of chemical and spectroscopic data by including ID and 2D NMR analyses.

关键词： Rhododendron lepidotum Flavone Coumarin

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