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Population genetic insights into the conservation of common walnut(Juglans regia)in Central Asia

Plant Diversity 2024年第5期46卷 600-610页

作者： Linjiang Ye Robabeh Shahi Shavvon Hailing Qi Hongyu Wu Pengzhen Fan mohammad nasir shalizi Safiullah Khurram Mamadzhanov Davletbek Yerlan Turuspekov Jie Liu CAS Key Laboratory for Plant Diversity and Biogeography of East Asia Kunming Institute of BotanyChinese Academy of SciencesKunming 650201YunnanChina Key Laboratory of Plant Resources and Biodiversity of Jiangxi Province Jingdezhen UniversityJingdezhen 333400JiangxiChina Germplasm Bank of Wild Species&Yunnan Key Laboratory of Crop Wild Relatives Omics Kunming Institute of BotanyChinese Academy of SciencesKunming 650201YunnanChina Department of Biology Faculty of ScienceYasouj UniversityYasouj 75918-74934Iran University of Chinese Academy of Sciences Beijing 100049China Department of Forestry and Environmental Resources North Carolina State UniversityRaleighNC 27695United States Department of Forestry and Natural Resources Faculty of AgricultureKabul UniversityKabul D-1006Afghanistan National Academy of Science of the Kyrgyz Republic Jalal-Abad Scientific CenterJalal-Abad 715600Kyrgyzstan Laboratory of Molecular Genetics Institute of Plant Biology and BiotechnologyAlmaty 050040Kazakhstan

The common walnut(Juglans regia)is one of the most economically important nut trees cultivated *** its importance,no comprehensive evaluation of walnut tree population genetics has been undertaken across the range where it originated,Central *** this study,we investigated the genetic diversity and population structure of 1082 individuals from 46 populations across Central *** found moderate genetic diversity of *** across Central Asia,with 46 populations clustered into three groups with a weak relationship between genetic and geographic *** findings reveal that the western Himalaya might be the core region of common walnut genetic diversity in Central Asia and that,except for two populations in Gongliu Wild Walnut Valley,humans might have introduced walnut populations to Xinjiang,*** observed distribution of the genetic landscape has probably been affected by historical climate fluctuation,breeding system,and prolonged anthropogenic *** propose the conservation of the core genetic diversity resources in the western Himalaya and pay special attention to populations from Gongliu in *** findings enhance our understanding of the genetic variation throughout the distribution range of *** in Central Asia,which will provide a key prerequisite for evidence-based conservation and management.

关键词： Central Asia Genetic diversity Germplasm management Gongliu wild walnut valley Juglans regia Western Himalaya

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Exploring Multi-Task Learning for Forecasting Energy-Cost Resource Allocation in IoT-Cloud Systems

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Computers, Materials & Continua 2024年第6期79卷 4603-4620页

作者： mohammad Aldossary Hatem A.Alharbi nasir Ayub Department of Computer Engineering and Information College of EngineeringPrince Sattam Bin Abdulaziz UniversityWadi Al-Dawasir11991Saudi Arabia Department of Computer Engineering College of Computer Science and EngineeringTaibah UniversityMadinah42353Saudi Arabia Department of Creative Technologies Air University IslamabadIslamabad44000Pakistan

Cloud computing has become increasingly popular due to its capacity to perform computations without relying on physical infrastructure,thereby revolutionizing computer ***,the rising energy consumption in cloud centers poses a significant challenge,especially with the escalating energy *** paper tackles this issue by introducing efficient solutions for data placement and node management,with a clear emphasis on the crucial role of the Internet of Things(IoT)throughout the research *** IoT assumes a pivotal role in this study by actively collecting real-time data from various sensors strategically positioned in and around data *** sensors continuously monitor vital parameters such as energy usage and temperature,thereby providing a comprehensive dataset for *** data generated by the IoT is seamlessly integrated into the Hybrid TCN-GRU-NBeat(NGT)model,enabling a dynamic and accurate representation of the current state of the data center *** the incorporation of the Seagull Optimization Algorithm(SOA),the NGT model optimizes storage migration strategies based on the latest information provided by IoT *** model is trained using 80%of the available dataset and subsequently tested on the remaining 20%.The results demonstrate the effectiveness of the proposed approach,with a Mean Squared Error(MSE)of 5.33%and a Mean Absolute Error(MAE)of 2.83%,accurately estimating power prices and leading to an average reduction of 23.88%in power ***,the integration of IoT data significantly enhances the accuracy of the NGT model,outperforming benchmark algorithms such as DenseNet,Support Vector Machine(SVM),Decision Trees,and *** NGT model achieves an impressive accuracy rate of 97.9%,surpassing the rates of 87%,83%,80%,and 79%,respectively,for the benchmark *** findings underscore the effectiveness of the proposed method in optimizing energy efficiency and enhancing the predictive

关键词： Cloud computing energy efficiency data center optimization internet of things(IoT) hybrid models

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Identifying the stability of housekeeping genes to be used for the quantitative real-time PCR normalization in retinal tissue of streptozotocin-induced diabetic rats

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International Journal of Ophthalmology(English edition) 2024年第5期17卷 794-805页

作者： Muhammad Zulfiqah Sadikan Nurul Alimah Abdul nasir mohammad Johari Ibahim Igor Iezhitsa Renu Agarwal Department of Pharmacology Faculty of MedicineManipal University College Malaysia(MUCM)Bukit BaruMelaka 75150Malaysia Centre for Neuroscience Research(NeuRon) Faculty of MedicineUniversiti Teknologi MARASungai Buloh CampusSungai BulohSelangor 47000Malaysia Department of Medical Education Faculty of MedicineUniversiti Teknologi MARASungai Buloh CampusSungai BulohSelangor 47000Malaysia Department of Biochemistry and Molecular Medicine Faculty of MedicineUniversiti Teknologi MARASungai Buloh CampusSungai BulohSelangor 47000Malaysia School of Medicine International Medical UniversityBukit JalilKuala Lumpur 57000Malaysia Department of Pharmacology and Bioinformatics Volgograd State Medical UniversityVolgograd 400131Russia

AIM:To investigate the stability of the seven housekeeping genes:beta-actin(ActB),glyceraldehyde-3-phosphate dehydrogenase(GAPDH),18s ribosomal unit 5(18s),cyclophilin A(CycA),hypoxanthine-guanine phosphoribosyl transferase(HPRT),ribosomal protein large P0(36B4)and terminal uridylyl transferase 1(U6)in the diabetic retinal tissue of rat ***:The expression of these seven genes in rat retinal tissues was determined using real-time quantitative reverse transcription polymerase chain reaction(RT-qPCR)in two groups;normal control rats and streptozotocininduced diabetic *** stability analysis of gene expression was investigated using geNorm,NormFinder,BestKeeper,and comparative delta-Ct(ΔCt)***:The 36B4 gene was stably expressed in the retinal tissues of normal control animals;however,it was less stable in diabetic *** 18s gene was expressed consistently in both normal control and diabetic rats’retinal *** this gene was the best reference for data normalisation in RT-qPCR studies that used the retinal tissue of streptozotocin-induced diabetic ***,there was no ideal gene stably expressed for use in all experimental ***:Identifying relevant genes is a need for achieving RT-qPCR validity and reliability and must be appropriately achieved based on a specific experimental setting.

关键词： housekeeping genes stability real-time reverse transcription polymerase chain reaction retinal tissue streptozotocin-induced diabetic rats

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From Entry to Evasion:A Comprehensive Analysis of Host-Virus Interactions for Monkeypox

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Infectious Microbes & Diseases 2024年第2期6卷 56-64页

作者： Vahideh Hamidi Sofiani mohammad Rezaei Zadeh Rukerd Javad Charostad mohammad Pardeshenas Reza Ghazi nasir Arefinia Sara Shafieipour Faranak Salajegheh Mohsen Nakhaie Department of Microbiology Golestan University of Medical SciencesGorganIran Gastroenterology and Hepatology Research Center Institute of Basic and Clinical Physiology SciencesKerman University of Medical SciencesKermanIran Universal Scientific Education and Research Network(USERN) TehranIran Department of Microbiology Faculty of MedicineShahid Sadoughi University of Medical SciencesYazdIran Department of Microbiology School of MedicineKerman University of Medical SciencesKermanIran Department of Biotechnology Golestan University of Medical SciencesGorganIran Student Research Committee Jiroft University of Medical SciencesJiroftIran Physiology Research Center Institute of NeuropharmacologyKerman University of Medical SciencesKermanIran Clinical Research Development Unit School of MedicineAfzalipour HospitalKerman University of Medical SciencesKermanIran

Monkeypox(Mpox)has posed a novel challenge and emerged as a threat to global public health since the onset of its outbreak in *** is spreading throughout the world in both endemic and non-endemic countries,indicating that its behavior is *** prevalence of Mpox and the risk of a global pandemic necessitate a better understanding of Mpox virus replications and interactions with the ***,we attempted to provide a detailed comprehensive review of Mpox virus behavior at the molecular level from the entry level to the establishment of a successful infection,including attachment and entry,DNA replication,protein expression and viron assembly and *** review also describes its strategies to evade host immune responses and inhibit apoptosis,and uncovers underlying molecular mechanisms such as subverted signaling pathways and cellular factors behind host-viral interactions.

关键词： monkeypox immunity apoptosis virus-host interaction

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Robust Control Design of Wheeled Inverted Pendulum Assistant Robot

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IEEE/CAA Journal of Automatica Sinica 2017年第4期4卷 628-638页

作者： Magdi S.Mahmoud mohammad T.nasir Systems Engineering Department King Fahd University of Petroleum and MineralsDhahran 31261Saudi Arabia

This paper examines the design concept and mobile control strategy of the human assistant robot I-PENTAR(inverted pendulum type assistant robot). The motion equation is derived considering the non-holonomic constraint of the twowheeled mobile robot. Different optimal control approaches are applied to a linearized model of I-PENTAR. These include linear quadratic regulator(LQR), linear quadratic Gaussian control(LQG), H_2 control and H_∞ control. Simulation is performed for all the approaches yielding good performance results.

关键词： I-PENTAR robot linear quadratic regulator(LQR) control design model predictive control(MPC) observerbased feedback control robust H_∞ control

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Bayesian Multidimensional Scaling for Location Awareness in Hybrid-Internet of Underwater Things

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IEEE/CAA Journal of Automatica Sinica 2022年第3期9卷 496-509页

作者： Ruhul Amin Khalil nasir Saeed mohammad Inayatullah Babar Tariqullah Jan Sadia Din IEEE Department of Electrical Engineering Faculty of Electrical and Computer EngineeringUniversity of Engineering and TechnologyPeshawar 25120Pakistan the Department of Electrical Engineering Northern Border UniversityArar 73222Saudi Arabia College of Science and Engineering Hamad Bin Khalifa UniversityDoha 34110Qatar

Localization of sensor nodes in the internet of underwater things(IoUT)is of considerable significance due to its various applications,such as navigation,data tagging,and detection of underwater ***,in this paper,we propose a hybrid Bayesian multidimensional scaling(BMDS)based localization technique that can work on a fully hybrid IoUT network where the nodes can communicate using either optical,magnetic induction,and acoustic *** communication technologies are already used for communication in the underwater environment;however,lacking localization *** and magnetic induction communication achieves higher data rates for short *** the contrary,acoustic waves provide a low data rate for long-range underwater *** proposed method collectively uses optical,magnetic induction,and acoustic communication-based ranging to estimate the underwater sensor nodes’final ***,we also analyze the proposed scheme by deriving the hybrid Cramer-Rao lower bound(H-CRLB).Simulation results provide a complete comparative analysis of the proposed method with the literature.

关键词： Bayesian multidimensional scaling(BMDS) hybrid Cramer-Rao lower bound(H-CRLB) internet of underwater things(IoUT) signals of opportunity(SOA)approach

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National guidelines for the diagnosis and treatment of hilar cholangiocarcinoma

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World Journal of Gastroenterology 2024年第9期30卷 1018-1042页

作者： Faisal Saud Dar Zaigham Abbas Irfan Ahmed Muhammad Atique Usman Iqbal Aujla Muhammad Azeemuddin Zeba Aziz Abu Bakar Hafeez Bhatti Tariq Ali Bangash Amna Subhan Butt Osama Tariq Butt Abdul Wahab Dogar Javed Iqbal Farooqi Faisal Hanif Jahanzaib Haider Siraj Haider Syed Mujahid Hassan Adnan Abdul Jabbar Aman Nawaz Khan Muhammad Shoaib Khan Muhammad Yasir Khan Amer Latif nasir Hassan Luck Ahmad Karim Malik Kamran Rashid Sohail Rashid mohammad Salih Abdullah Saeed Amjad Salamat Ghias-un-Nabi Tayyab Aasim Yusuf Haseeb Haider Zia Ammara Naveed Department of Hepatopancreatic Biliary Surgery&Liver Transplant Pakistan Kidney and Liver Institute&Research CentreLahore 54000Pakistan Department of Hepatogastroenterology and Liver Transplantation Dr.Ziauddin University HospitalKarachi 75600SindhPakistan University of Aberdeen Aberdeen B243FXUnited Kingdom Department of Pathology Pakistan Kidney and Liver Institute&Research CentreLahore 54000Pakistan Department of Gastroenterology&Hepatology Pakistan Kidney and Liver Institute&Research CentreLahore 54000Pakistan Department of Radiology Aga Khan UniversityKarachi 74800Pakistan Department of Oncology Hameed Latif HospitalLahore 54000Pakistan Division of Hepatopancreatic Biliary Surgery&Liver Transplantation Shifa International HospitalIslamabad 44000Pakistan Department of Hepatopancreatic Biliary Surgery&Liver Transplant Shaikh Zayed Hospital and Post Graduate Medical InstituteLahore 54000Pakistan Department of Medicine Aga Khan University HospitalKarachi 74800Pakistan Department of Liver Transplant Pir Abdul Qadir Shah Jeelani Institute of Medical SciencesGambat 66020Pakistan Department of Medicine&Gastroenterology Lifecare Hospital and Research CentrePeshawar 25000Khyber PakhtunkhwaPakistan Department of Hepatopancreatobiliary&Liver Transplant Bahria International HospitalLahore 54000Pakistan Department of Surgery Hepatopancreatobiliary&Liver TransplantDow University of Health SciencesKarachi 74800Pakistan Department of Gastroenterology Hepatology&NutritionPir Abdul Qadir Shah Jeelani Institute of Medical SciencesGambat 66020Pakistan Department of Oncology Dr.Ziauddin HospitalKarachi 74800Pakistan Department of Radiology Rehman Medical InstitutePeshawar 25000Pakistan Army Liver Transplant Unit Pak Emirates Military HospitalRawalpindi 46000Pakistan Department of Gastroenterology Sindh Institute of Urology and TransplantationKarachi 75500Pakistan Rashid Nursing Home and Cancer Clinic Rashid Nursing Home and Cancer ClinicRawalpindi 46000Pakistan Department of Gastroentero

A consensus meeting of national experts from all major national hepatobiliary centres in the country was held on May 26,2023,at the Pakistan Kidney and Liver Institute&Research Centre(PKLI&RC)after initial consultations with the *** Pakistan Society for the Study of Liver Diseases(PSSLD)and PKLI&RC jointly organised this *** effort was based on a comprehensive literature review to establish national practice guidelines for hilar cholangiocarcinoma(hCCA).The consensus was that hCCA is a complex disease and requires a multidisciplinary team approach to best manage these *** coordinated effort can minimise delays and give patients a chance for curative treatment and effective *** diagnostic and staging workup includes high-quality computed tomography,magnetic resonance imaging,and magnetic resonance *** cytology or biopsy utilizing endoscopic retrograde cholangiopancreatography is a mainstay for ***,histopathologic confirmation is not always required before *** ultrasound with fine needle aspiration of regional lymph nodes and positron emission tomography scan are valuable adjuncts for *** only curative treatment is the surgical resection of the biliary tree based on the Bismuth-Corlette *** patients with unresectable hCCA can be considered for liver *** chemotherapy should be offered to patients with a high risk of *** use of preoperative biliary drainage and the need for portal vein embolisation should be based on local multidisciplinary *** with acute cholangitis can be drained with endoscopic or percutaneous biliary *** chemotherapy with cisplatin and gemcitabine has shown improved survival in patients with irresectable and recurrent hCCA.

关键词： Hilar cholangiocarcinoma Bismuth-Corlette classification Memorial Sloan Kettering Cancer Centre Staging Preoperative biliary drainage Portal vein embolisation Surgical resection Hepatectomy

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Customer Prioritization for Medical Supply Chain During COVID-19 Pandemic

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Computers, Materials & Continua 2022年第1期70卷 59-72页

作者： Iram Mushtaq Muhammad Umer Muhammad Imran Inzamam Mashood nasir Ghulam Muhammad mohammad Shorfuzzaman Department of Management Sciences Sir Syed CASE Institute of Technology45230IslamabadPakistan Department of Operation&Supply Chain Management NUST Business SchoolNational University of Sciences&Technology45200IslamabadPakistan Department of Computer Science HITEC University TaxilaTaxilaPakistan Department of Computer Engineering College of Computer and Information SciencesKing Saud UniversityRiyadhSaudi Arabia Department of Computer Science College of Computers and Information TechnologyTaif UniversityTaif21944Saudi Arabia

During COVID-19,the escalated demand for various pharmaceutical products with the existing production capacity of pharmaceutical companies has stirred the need to prioritize its customers in order to fulfill their *** study considers a two-echelon pharmaceutical supply chain considering various pharma-distributors as its suppliers and hospitals,pharmacies,and retail stores as its *** studies have generally considered a balanced situation in terms of supply and demand whereas this study considers a special situation of COVID-19 pandemic where demand exceeds supply Various criteria have been identified from the literature that influences the selection of customers.A questionnaire has been developed to collect primary data from pharmaceutical suppliers pertaining to customerselection *** criteria have been prioritized with respect to eigenvalues obtained from Principal Component Analysis and also validated with the experts’domain-related knowledge using Analytical Hierarchy *** potential appeared to be the most important criteria of customer selection followed by trust and service convenience brand loyalty,commitment,brand awareness,brand image,sustainable behavior,and ***,Multi Criteria Decision Analysis has been performed to prioritize the customerselection criteria and customers with respect to selection *** experts with seven and three and ten years of experience have participated in the *** of the study suggest large hospitals,large pharmacies,and small retail stores are the highly preferred ***,findings of prioritization of customer-selection criteria fromboth Principal Component Analysis and Analytical Hierarchy Process are ***,this study considers the experience of three experts to calculate an aggregate score of priorities to reach an effective *** traditional supply chain problems of supplier selection,this study considers a selection

关键词： Pandemic customer prioritization pharmaceutical supply chain principal component analysis multi-criteria decision-making

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Effect of Cobalt Doping on the Microstructure and Tensile Properties of Lead Free Solder Joint Subjected to Electromigration

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Journal of Materials Science & Technology 2016年第11期32卷 1129-1136页

作者： M.nasir Bashir A.S.M.A.Haseeb Abu Zayed mohammad Saliqur Rahman M.A.Fazal Department of Mechanical Engineering University of Malaya

Rapid Cu diffusion is one of the main causes of electromigration（EM） failure in lead-free solder *** this study, an effort has been made to investigate the detrimental effects of EM on microstructure and mechanical performance of solder joint by introducing Co nanoparticles（NP） doped flux at the interface between SAC305 solder and copper substrate. EM tests were conducted on un-doped SAC305 and Co-doped SAC305 solder joints for different time intervals, with the maximum duration of 1128 h. A DC current was applied to the both types of solder joints to achieve a current density of 1 × 104A/cm2. EM tests were performed in an oil bath maintained at a constant temperature of 80 °C. It is found that Codoped flux significantly reduced the formation of cracks and voids at the cathode interface. Co atoms entered into the lattice of Cu6Sn5 leading to the formation of（Cu, Co）6Sn5. This thermodynamically stabilized the interfacial intermetallic（IMC） layers both at the anode and cathode sides and suppressed the change in their thickness. The average anodic growth rate of（Cu, Co）6Sn5 interfacial IMC in the doped sample was about one order of magnitude lower compared with that of Cu6Sn5 in the un-doped ***-NP also improved the tensile strength considerably before and after EM. The report suggests that the reliability of solder joint during EM can be improved by using Co-NP doped flux.

关键词： Electromigration damages Tensile strength Intermetallic compounds Nanoparticles Reliability

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Nitrogen in Relation to Photosynthetic Capacity and Accumulation of Osmoprotectant and Nutrients in Brassica Genotypes Grown Under Salt Stress

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Agricultural Sciences in China 2010年第5期9卷 671-680页

作者： Manzer H Siddiqui Firoz mohammad M nasir Khan Mohamed H Al-Whaibi Ali H A Bahkali Department of Botany & Microbiology College of Science King Saud University Plant Physiology Section Department of Botany Aligarh Muslim University

Different strategies of the application of nutrients are required to overcome the adverse effects of mustard （Brassica juncea L.） in response to NaCl stress. The objective of the present study was to determine if different added levels of nitrogen （N） in growth medium could alleviate the adverse effects of salt stress on photosynthetic capacity and accumulation of osmoprotectants and nutrients. 14 days mustard seedlings of salt-sensitive （cv. Chuutki） and salt-tolerant （cv. Radha） genotypes were fed with：（i） 0 mmol L^-1 NaCl ＋ 0 mg N kg^-1 sand （control）, （ii） 90 mmol L^-1 NaCl ＋ 30 mg N kg^-1 sand, （iii） 90 mmol L^-1 NaCl ＋60 mg N kg^-1 sand, （iv） 90 mmol L^-1 NaCl ＋90 mg N kg^-1 sand and （v） 90 mmol L^-1NaCl＋ 120 mg N kg^-1 sand. Under the condition of salinity stress, N application caused a significant ameliorative effect on both genotypes with respect to growth attributes [fresh weight （FW） and dry weight （DW）] and physio-biochemical parameters [percent water content （WC）, net photosynthetic rate （PN）, stomatal conductance （gs）, total chlorophyll （Ch1）, carbonic anhydrase （CA） activity and malondialdehyde （MDA）, nitrogen （N）, potassium （K） and sodium （Na） contents, and K/Na ratio] and yield attributes （number of pods/plant, seeds/pod and seed yield/plant）. The salt-tolerant genotype exhibited maximum value for growth, physio-biochemical and yield attributes at 60 mg N kg 1 sand than that of salt-sensitive genotype. These results suggest that application of N may ameliorate most of the attributes and prove to be a physiological remedy to increase the tolerance against the ill effects of salt stress in Brassicas.

关键词： Brassica juncea L. carbonic anhydrase activity malondialdehyde net photosynthetic rate osmoprotectants,salt stress

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