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Role of cytomegalovirus on the maturation and function of monocyte derived dendritic cells of liver transplant patients

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World Journal of Transplantation 2016年第2期6卷 336-346页

作者： mohammad hossein Karimi Afsoon Shariat Ramin Yaghobi Talat Mokhtariazad Seyed mohammad Moazzeni Shiraz Trans-plant Research Center Shiraz University of Medical Sciences Department of Microbiology Faculty of Basic SciencesKazerun BranchIslamic Azad University College of Basic Sciences Tehran Science and Research BranchIslamic Azad University Department of Virology School of Public HealthTehran University of Medical Sciences Department of Immunology Faculty of Medical SciencesTarbiat Modarres University

AIM: To study the impact of association between cytomegalovirus(CMV) pathogenesis with dendritic cell(DC) maturation and function was evaluated in CMV reactivated liver transplanted patients in comparing with non-reactivated ones, and healthy controls. METHODS: Monocyte derived dendritic cells(Mo DCs) was generated from collected ethylenediaminetetraacetic acid-treated blood samples from patient groups and controls. In these groups, expression rates and mean fluorescent intensity of DC markers were evaluated using flowcytometry technique. Secretion of cytokines including: interleukin(IL)-6, IL-12 and IL-23 were determined using enzyme-linked immunosorbent assay methods. The gene expression of toll-like receptor 2(TLR2), TLR4 and IL-23 were analyzed using in-house real-time polymerase chain reaction ***: Results have been shown significant decreases in: Expression rates of Mo DC markers including CD83, CD1 a and human leukocyte antigen DR(HLA-DR), the mean fluorescence intensitys for CD1 a and HLA-DR, and secretion of IL-12 in CMV reactivated comparedwith non-reactivated liver transplanted patients. On the other hand, significant increases have been shown in the secretions of IL-6 and IL-23 and gene expression levels of TLR2, TLR4 and IL-23 from Mo DCs in CMV reactivated compared with non-reactivated liver transplanted recipients. CONCLUSION: DC functional defects in CMV reactivated recipients, such as decrease in expression of DC maturation markers, increase in secretion of proinflammatory cytokines, and TLRs can emphasize on the importance of CMV infectivity in development of liver rejection in transplanted patients.

关键词： Cytomegalovirus Dendritic cells Liver transplantation

Comparison of chest CT scan findings between COVID-19 and pulmonary contusion in trauma patients based on RSNA criteria:Established novel criteria for trauma victims

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Chinese Journal of Traumatology 2022年第3期25卷 170-176页

作者： hossein Abdolrahimzadeh Fard Salahaddin Mahmudi-Azer Qusay Abdulzahraa Yaqoob Golnar Sabetian Pooya Iranpour Zahra Shayan Shahram Bolandparvaz Hamid Reza Abbasi Shiva Aminnia Maryam Salimi mohammad Mehdi Mahmoudi Shahram Paydara Roham Borazjani Ali Taheri Akerdi Masome Zare Leila Shayan mohammadreza Sasani Trauma Research Center Shahid Rajaee(Emtiaz)Trauma HospitalShiraz University of Medical SciencesShirazIran Department of General Surgery Kufa University of Medical SciencesNajafIraq Department of Intensive Care Medicine Trauma Research CenterShahid Rajaee(Emtiaz)HospitalShiraz University of Medical SciencesShirazIran Department of Radiology Medical Imaging Research Center.School of MedicineShiraz University of Medical SciencesShirazIran Department of Biostatistics Trauma Research CenterSchool of MedicineShiraz University of Medical SciencesShirazIran Student Research Committee Shiraz University of Medical SciencesShirazIran Trauma Intensive Care Unit Trauma Research CenterShahid Rajaee(Emtiaz)Trauma HospitalShiraz University of Medical SciencesShirazIran

Propose:In this study,we re-assessed the criteria defined by the radiological society of North America(RSNA)to determine novel radiological findings helping the physicians differentiating COVID-19 from pulmonary ***:All trauma patients with blunt chest wall trauma and subsequent pulmonary contusion,COVID-19-related signs and symptoms before the trauma were enrolled in this retrospective study from February to May *** patients(Group P)were then classified into two groups based on polymerase chain reaction tests(Group Pa for positive patients and Pb for negative ones).Moreover,44 patients from the prepandemic period(Group PP)were *** were matched to Group P regarding age,sex,and trauma-related *** radiologists blindly reviewed the CT images of all enrolled patients according to criteria defined by the RSNA *** radiological findings were compared between Group P and Group PP;statistically significant ones were re-evaluated between Group Pa and Group Pb ***,the sensitivity and specificity of each significant findings were *** Chi-square test was used to compare the radiologica丨findings between Group P and Group ***:In the Group PP,73.7%of all ground-glass opacities(GGOs)and 80%of all multiple bilateral GGOs were detected(p<0.001 and p=0.25,respectively).Single bilateral GGOs were only seen among the Group *** Chi-square tests showed that the prevalence of diffused GGOs,multiple unilateral GGOs,multiple consolidations,and multiple bilateral consolidations were significantly higher in the Group P(p=0.001,0.01,0.003,and 0.003,respectively).However,GGOs with irregular borders and single consolidations were more significant among the Group PP(p=0.01 and 0.003,respectively).Of note,reticular distortions and subpleural spares were exclusively detected in the Group ***:We concluded that the criteria set by RSNA for the diagnosis of COVID-19 are not appropriate in trauma ***

关键词： Chest wall CT Contusion COVID-19 RSNA criteria Trauma

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Analysis and Evaluation of Thermal-cooling Loads of Office Buildings Using Carrier Software in Iran

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Journal of Smart Buildings and Construction Technology 2022年第2期4卷 61-74页

作者： Rahim Zahedi Siavash Gitifar mohammad hasan Ghodusinejad Alireza Aslani hossein Yousefi Department of Renewable Energy and Environment University of TehranTehranIran Faculty of Mechanical Engineering Iran University of Science and TechnologyTehranIran

The importance and necessity of energy saving in the world have been discussed for many years,but achieving a logical and transparent solution is still one of the main challenges and problems of the world’s *** rapid growth of energy consumption in the last two decades has caused the security of the domestic energy supply of buildings to face serious prob*** this research,first by entering parameters such as the type of materials,doors and windows,and the type of soil on the floor connected to the ground,*** the heat and cold load calculation software(HAP Carrier)as the design calculations and then in the second step entering the specifications inferred from the Iran’s national building code as a reference for energy saving calculations,calculations are performed and compared as the first criterion,and finally these two outputs are *** actual energy consumption and determination of the building energy consumption index are determined as another criterion,as well as the degree of deviation from the actual *** results showed that the theoretical method and the thermal and refrigeration load calculations of the Zanjan Gas Company building have 6%difference in cooling load but the heating load is about 34%different,which means for cooling loads,the theoretical model can be used with high accuracy but for heating loads,the national building code needs fundamental changes.

关键词： Large space building Building operational performance Building energy efficiency Heating Ventilation and air conditioning systems

A novel approach for detection of deception using Smoothed Pseudo Wigner-Ville Distribution (SPWVD)

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Journal of Biomedical Science and Engineering 2013年第1期6卷 8-18页

作者： Elias Ebrahimzadeh Seyed mohammad Alavi Ahmad Bijar Alireza Pakkhesal Department of Biomedical Engineering Shahed University Tehran Iran Faculty of Engineering Islamic Azad University South Tehran Branch Tehran Iran Faculty of Information and Communication Technology Engineering Imam Hossein University Tehran Iran

For many years, the uncertainty of lie-detection systems has been one of the concerns of defense related agencies. Clearly the results of these systems must be generalized by a high value of accuracy to be acceptable by judicial systems. In this paper, a new method based on P300-based component has been proposed for lie-detection. In this regard, the test protocol is designed based on Odd-ball paradigm concealed information recognition. This test was done on 32 people and their brain signals were acquired. After preprocessing, the classic features are extracted from each single trial. After that, time-frequency (TF) transformation is applied on the sweeps and TF features are produced thereupon. Then, the best combinational feature vector is selected in order to improve classifier accuracy. Finally, Guilty and Innocent persons are classified by KNN and MLP. We found that combination of Time-Frequency and Classic features have better ability to achieve higher amount of accuracy. The obtained results show that the proposed method can detect deception by the accuracy of 89.73% which is better than other previously reported methods.

关键词： Lie-Detection Electroencephalography (EEG) P300 Component Odd-Ball Paradigm Time-Frequency Transform

Darboux Transformation in Quantum Black-Scholes Hamiltonian and Supersymmetry

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Open Journal of Microphysics 2013年第2期3卷 43-46页

作者： Jafar Sadeghi mohammad Rostami Ahmad Pourdarvish Behnam Pourhassan Department of Physics Imam Hossein University Tehran Iran Department of Physics Islamic Azad University—Ayatollah Amoli Branch Amol Iran Department of Statistics Mazandaran University Babolsar Iran

In this paper, we consider the Black-Scholes (BS) equation for option pricing with constant volatility. Here, we construct the first-order Darboux transformation and the real valued condition of transformed potential for BS corresponding equation. In that case we also obtain the transformed of potential and wave function. Finally, we discuss the factorization method and investigate the supersymmetry aspect of such corresponding equation. Also we show that the first order equation is satisfied by commutative algebra.

关键词： Black-Scholes Hamiltonian Darboux Transformation Supersymmetry

Invasive candidiasis in critical care setting, updated recommendations from “Invasive Fungal Infections-Clinical Forum”, Iran

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World Journal of Critical Care Medicine 2014年第4期3卷 102-112页

作者： Ashraf Elhoufi Arezoo Ahmadi Amir mohammad Hashem Asnaashari mohammad Ali Davarpanah Behrooz Farzanegan Bidgoli Omid Moradi Moghaddam mohammad Torabi-Nami Saeed Abbasi Malak El-Sobky Ali Ghaziani mohammad hossein Jarrahzadeh Reza Shahrami Farzad Shirazian Farhad Soltani Homeira Yazdinejad Farid Zand Department of Critical Care Medicine Dubai Hospital Dubai Health Authority Department of Anesthesiology and Critical Care Sina Hospital Tehran University of Medical Sciences Department of Pulmonology and Critical Care Ghaem Hospital Mashhad University of Medical Sciences Department of Infectious Diseases and Tropical Medicine Shiraz University of Medical Sciences Tracheal Disease Research Center Shahid Behesti University of Medical Sciences Department of Anesthesiology and Critical Care Rasoul-e-Akram Hospital Iran University of Medical Sciences Department of Neuroscience School of Advanced Medical Sciences and Technologies Shiraz University of Medical Sciences Behphar Scientific Committee Behphar Group Anesthesiology and Critical Care Research Center Isfahan University of Medical Sciences Invasive Fungal Infections-Clinical Forum Intensive Care and Burn Units Motahhari Hospital Intensive Care Unit Vali-e-Asr Hospital NAJA University Department of Anesthesiology and Critical Care Golestan Hospital Ahwaz Jundishapur University of Medical Sciences Department of Anesthesiology and Critical Care Taleghani Hospital Shahid Beheshti University of Medical Sciences Shiraz Anesthesiology and Critical Care Research Center Shiraz University of Medical Sciences

Invasive candidiasis(IC) bears a high risk of morbidity and mortality in the intensive care units(ICU). With the current advances in critical care and the use of widespectrum antibiotics, invasive fungal infections(IFIs) and IC in particular, have turned into a growing concern in the ICU. Further to blood cultures, some auxil-iary laboratory tests and biomarkers are developed to enable an earlier detection of infection, however these test are neither consistently available nor validated in our setting. On the other hand, patients' clinical status and local epidemiology data may justify the empiric antifungal approach using the proper antifungal option. The clinical approach to the management of IC in febrile, non-neutropenic critically ill patients has been defined in available international guidelines; nevertheless such recommendations need to be customized when applied to our local practice. Over the past three years, Iranian experts from intensive care and infectious diseases disciplines have tried to draw a consensus on the management of IFI with a particular focus on IC in the ICU. The established IFI-clinical forum(IFI-CF), comprising the scientific leaders in the field, has recently come up with and updated recommendation on the same(June 2014). The purpose of this review is to put together literature insights and Iranian experts' opinion at the IFI-CF, to propose an updated practical overview on recommended approaches for the management of IC in the ICU.

关键词： Invasive candidiasis Intensive care unit IFI-clinical forum Recommendations Iran

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西亚安全秩序变革的结构性要素分析

国际关系研究 2019年第6期 128-150,M0007,M0008页

作者：穆罕默德·雷扎·戴赫什里侯赛因·沙莫拉蒂陈佳骏伊朗外交部附属国际关系学院国际关系系伊朗外交部附属国际关系学院上海市美国问题研究所

本文分析了西亚秩序与安全的新趋势,该趋势源于在各方面影响或改变地区秩序的驱动力,如以相互关联方式发挥作用的结构、行为体和新进程等。由于西亚地区充满了不确定性和不可预测性,而且最重要的是规范性准则的缺乏、行为体的多元化以... 详细信息

本文分析了西亚秩序与安全的新趋势,该趋势源于在各方面影响或改变地区秩序的驱动力,如以相互关联方式发挥作用的结构、行为体和新进程等。由于西亚地区充满了不确定性和不可预测性,而且最重要的是规范性准则的缺乏、行为体的多元化以及塑造地区秩序的不均衡域外进程,导致该地区的安全行为体陷入困境。当前西亚局势的最终解决方案似乎只有集体安全倡议,如已经提出的建立牢固的地区和网络安全以及建立地区对话论坛。

关键词：地区秩序与安全新趋势西亚全方位平衡次国家行为者

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超越“数字游民”:数字游牧工作及其技术应用

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青年探索 2023年第6期 102-110页

作者：凯莉斯·纳什穆罕默德·侯赛因·贾拉希威尔·萨瑟兰加布里埃拉·菲利普斯姚建华(译) 徐偲骕(译) 美国北卡罗来纳大学教堂山分校信息与图书馆学院美国华盛顿大学设计与工程系复旦大学新闻学院复旦大学马克思主义新闻观教学与研究基地上海大学新闻传播学院上海大学中国当代文化研究中心

近年来,“数字游牧”作为一种时尚且颠覆传统的生活方式,受到越来越多年轻人的追捧。然而,学术界对于数字游牧生活方式的特征、对未来工作的影响以及支持它的技术,还缺乏深入的实证研究。本文描述和阐释了构成数字游牧工作的四个关键要... 详细信息

近年来,“数字游牧”作为一种时尚且颠覆传统的生活方式,受到越来越多年轻人的追捧。然而,学术界对于数字游牧生活方式的特征、对未来工作的影响以及支持它的技术,还缺乏深入的实证研究。本文描述和阐释了构成数字游牧工作的四个关键要素:(1)数字工作(digital work);(2)零工工作(gig work);(3)游牧工作(nomadic work);(4)冒险与全球旅行(adventure and global travel)。本文认为,数字游民处于上述四个要素的交汇点上,且每个要素都与数字技术的使用紧密交织。本研究旨在考察和探究数字游牧工作的定义以及数字技术在其中的应用过程,揭示数字游民、新兴数字平台和未来工作之间的复杂动态关系。

关键词：数字游民零工工作游牧工作数字工作

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FungalTraits:a user-friendly traits database of fungi and fungus-like stramenopiles

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Fungal Diversity 2020年第2期107卷 I0001-I0016页

作者： Sergei Põlme Kessy Abarenkov RHenrik Nilsson Björn D.Lindahl Karina Engelbrecht Clemmensen Havard Kauserud Nhu Nguyen Rasmus Kjøller Scott T.Bates Petr Baldrian Tobias Guldberg Frøslev Kristjan Adojaan Alfredo Vizzini Ave Suija Donald Pfister Hans-Otto Baral Helle Järv Hugo Madrid Jenni Nordén Jian-Kui Liu Julia Pawlowska Kadri Põldmaa Kadri Pärtel Kadri Runnel Karen Hansen Karl-Henrik Larsson Kevin David Hyde Marcelo Sandoval-Denis Matthew E.Smith Merje Toome-Heller Nalin N.Wijayawardene Nelson Menolli Jr Nicole K.Reynolds Rein Drenkhan Sajeewa S.N.Maharachchikumbura Tatiana B.Gibertoni Thomas Læssøe William Davis Yuri Tokarev Adriana Corrales Adriene Mayra Soares Ahto Agan Alexandre Reis Machado Andrés Argüelles-Moyao Andrew Detheridge Angelina de Meiras-Ottoni Annemieke Verbeken Arun Kumar Dutta Bao-Kai Cui C.K.Pradeep César Marín Daniel Stanton Daniyal Gohar Dhanushka N.Wanasinghe Eveli Otsing Farzad Aslani Gareth W.Griffith Thorsten H.Lumbsch Hans-Peter Grossart hossein Masigol Ina Timling Inga Hiiesalu Jane Oja John Y.Kupagme József Geml Julieta Alvarez-Manjarrez Kai Ilves Kaire Loit Kalev Adamson Kazuhide Nara Kati Küngas Keilor Rojas-Jimenez Krišs Bitenieks Laszlo Irinyi LászlóGNagy Liina Soonvald Li-Wei Zhou Lysett Wagner M.Catherine Aime MaarjaÖpik María Isabel Mujica Martin Metsoja Martin Ryberg Martti Vasar Masao Murata Matthew PNelsen Michelle Cleary Milan C.Samarakoon Mingkwan Doilom mohammad Bahram Niloufar Hagh-Doust Olesya Dulya Peter Johnston Petr Kohout Qian Chen Qing Tian Rajasree Nandi Rasekh Amiri Rekhani Hansika Perera Renata dos Santos Chikowski Renato L.Mendes-Alvarenga Roberto Garibay-Orijel Robin Gielen Rungtiwa Phookamsak Ruvishika S.Jayawardena Saleh Rahimlou Samantha C.Karunarathna Saowaluck Tibpromma Shawn P.Brown Siim-Kaarel Sepp Sunil Mundra Zhu-Hua Luo Tanay Bose Tanel Vahter Tarquin Netherway Teng Yang Tom May Torda Varga Wei Li Victor Rafael Matos Coimbra Virton Rodrigo Targino de Oliveira Vitor Xavier de Lima Vladimir S.Mikryukov Yongzhong Lu Yosuke Matsuda Yumiko Miyamoto Urm Institute of Ecology and Earth Sciences University of Tartu14A Ravila50411 TartuEstonia Natural History Museum University of Tartu46 Vanemuise Str51003 TartuEstonia Gothenburg Global Biodiversity Centre Box 46140530 GothenburgSweden Department of Biological and Environmental Sciences University of GothenburgGothenburgSweden Department of Soil and Environment Swedish University of Agricultural SciencesBox 701475007 UppsalaSweden Department of Forest Mycology and Plant Pathology Swedish University of Agricultural SciencesBox 702675007 UppsalaSweden Section for Genetics and Evolutionary Biology(EvoGene) Department of BiosciencesUniversity of OsloP.O.Box 1066BlindernNO-0316 OsloNorway University of Hawaiʻi at Mānoa 3190 Maile WaySt.John 102HonoluluHIUSA Department of Biology University of CopenhagenUniversitetsparken 152100 CopenhagenØDenmark Purdue University Northwest WestvilleIN 46391USA Institute of Microbiology Czech Academy of SciencesVidenska 108314220 Praha 4Czech Republic GLOBE Institute University of CopenhagenØster Farimagsgade 5KH7.2.321353 CopenhagenDenmark Dipartimento di Scienze della Vita e Biologia dei Sistemi Universitàdi TorinoViale Mattioli 2510125 TorinoItaly Department of Organismic and Evolutionary Biology and Farlow Library and Herbarium Harvard University22 Divinity AveCambridgeMA 02138USA Blaihofstr.42 72074 TübingenGermany SYNLAB Estonia Veerenni 53aTallinn 11313Estonia Escuela de Tecnología Médica Universidad Santo TomásLos Carreras 753OsornoChile Centro de Genómica y Bioinformática Universidad MayorCamino La Pirámide 5750HuechurabaSantiagoChile Norwegian Institute for Nature Research(NINA) Sognsveien 680855 OsloNorway School of Life Science and Technology University of Electronic Science and Technology of ChinaChengdu 611731People’s Republic of China Evolutionary Biology Faculty of BiologyBiological and Chemical Research CentreUniversity of Warsawul.Zwirki i Wigury 10102-089 WarsawPoland Department of Botany Swedish Museum of

The cryptic lifestyle of most fungi necessitates molecular identification of the guild in environmental *** the past decades,rapid development and affordability of molecular tools have tremendously improved insights of the fungal diversity in all ecosystems and ***,in spite of the progress of molecular methods,knowledge about functional properties of the fungal taxa is vague and interpretation of environmental studies in an ecologically meaningful manner remains *** order to facilitate functional assignments and ecological interpretation of environmental studies we introduce a user friendly traits and character database FungalTraits operating at genus and species hypothesis *** the information from previous efforts such as FUNGuild and FunFun together with involvement of expert knowledge,we reannotated 10,210 and 151 fungal and Stramenopila genera,*** resulted in a stand-alone spreadsheet dataset covering 17 lifestyle related traits of fungal and Stramenopila genera,designed for rapid functional assignments of environmental *** order to assign the trait states to fungal species hypotheses,the scientific community of experts manually categorised and assigned available trait information to 697,413 fungal ITS *** the basis of those sequences we were able to summarise trait and host information into 92,623 fungal species hypotheses at 1%dissimilarity threshold.

关键词： Fungal traits Trophic modes Function Guild Bioinformatics High-throughput sequencing Community ecology