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Effect of green tea consumption in treatment of mild to moderate depression in Iranian patients living with HIV: A double-blind randomized clinical trial

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Chinese Herbal Medicines 2021年第1期13卷 136-141页

作者： Dehghan Manshadi Seyed Ali Mousavi Seyed Alireza salehi mohammad Reza Zebardast Jayran SeyedAlinaghi SeyedAhmad Rezazade Shams Ali Mirhoseinian Seyed Saeid Asadollahi-Amin Ali Department of Infectious Diseases and Tropical Medicine Imam-Khomeini Hospital ComplexTehran University of Medical SciencesTehranTehran 11519Iran Department of Infectious Diseases and Tropical Medicine Shahid Sadoughi HospitalShahid Sadoughi University of Medical Sciences and Health ServicesYazd 11519Iran Cognitive Neuroscience Linguistics Institute for Cognitive Science Studies(ICSS)Tehran 11519Iran Iranian Research Center for HIV/AIDS Iranian Institute for Reduction of High-Risk BehaviorsTehran University of Medical SciencesTehran 11519Iran Medicinal Plants Research Center Institute of Medicinal PlantsACECRTehran 11519Iran Department of Pharmacognosy Faculty of Pharmacy.Tehran University of Medical Sciences.Tehran 11519Iran

Objective: Depression affects people living with HIV(PLWH) compliance leading to poor control *** observational studies showed an anti-depression effect of green tea extract(GTE). The therapeutic effect of GTE on depression were investigated in PLWH receiving antiretroviral therapy(ART).Methods: Fifty PLWH on ART with diagnose of mild to moderate of depression, participated in a doubleblind, placebo-controlled trial and underwent 12 weeks of treatment with either 400 mg GTE capsules or placebo twice daily. The Hamilton depression scale of patients was measured before, 6 weeks and 12 weeks after treatment in two groups. The primary outcome measure was performed to evaluate the efficacy of GTE in improving depressive ***: The mean of Hamilton score showed a significant difference between the two groups after 12 weeks(P = 0.035). Repeated measures ANOVA test showed a significant effect for time ? treatment interaction on the Hamilton mean score between the two groups(P = 0.000).Conclusion: It seems the use of GTE capsules in PLWH on ART is safe and could lead to greater and more rapid improvement in depressive symptoms than placebo. Thus it can be considered as an alternative therapy for mild to moderate depression. Further studies with higher sample size and longer followup and comparisons with other antidepressive drugs are warranted.

关键词： depression green tea HIV

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Effect of Cr elimination on flow behavior and processing map of newly developed ECO-7175 aluminum alloy during hot compression

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Transactions of Nonferrous Metals Society of China 2022年第5期32卷 1442-1459页

作者： Majid SEYED-salehi Bong Hwan KIM Seung Yoon YANG Shae Kwang KIM Ghasem EISAABADI BOZCHALOEI Faculty of Materials Science and Engineering K.N.Toosi University of Technology***TehranIran Korea Institute of Industrial Technology 7-47 Songdo-dongIncheon 406-840Korea Department of Advanced Materials Science and Engineering Sungkyunkwan UniversitySuwon 16419Korea Department of Materials Science and Engineering Faculty of EngineeringArak University***ArakIran

ECO-Al alloys are introduced as a game-changer for the aluminum industry and it is of utmost importance to determine the role of alloying elements in their processing *** this study,the effects of Cr on the hot deformation behavior of newly-developed ECO-7175 alloy were ***-7175 samples with and without Cr were hot-compressed using a Gleeble simulator(temperature range of 350−500℃ and strain rates of 0.001−1 s^(−1)).The results were used to study the constitutive equations,the processing maps,and the microstructural evolution of the *** Cr-containing alloy,the analysis of the deformation activation energy reveals that the rate-controlling mechanisms of the deformation change gradually from self-diffusion of Al(or diffusion of Mg in Al)to diffusion of Cr in Al by decreasing the Zener−Hollomon *** analysis of the processing maps of Cr-containing alloy shows that the dynamic recrystallization(DRX)zone is limited to the deformation at high temperatures and low strain rates and expands with increasing applied *** the other hand,it is found that the self-diffusion of Al(or Mg in Al)is the only rate-controlling mechanism during hot deformation of Cr-free alloy in all processing conditions and its DRX zone is independent of the plastic strain.

关键词： hot deformation constitutive equation processing map ECO-7175 aluminum alloy

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The antimicrobial susceptibility profile of ESKAPE pathogens from urinary tract infections in a referral laboratory,Northeast Iran

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Journal of Coastal Life Medicine 2016年第12期4卷 980-982页

作者： mohammad salehi Abdolmajid Ghasemian Seyyed Khalil Shokouhi Mostafavi Farshad Nojoomi mohammad Karim Rahimi Research Center for HIV/AIDS HTLV and Viral HepatitisIranian Academic Center for EducationCulture and Research(ACECR)Khorasan Razavi BranchMashhadIran Medical Diagnostic Laboratory of Neyshabour Center of MedicalPathological and Genetic Diagnostic ServicesIranian Academic Center for EducationCulture and Research(ACECR)Mashhad BranchMashhadIran Microbiology Department Faculty of MedicineAJA University of Medical SciencesTehranIran Department of Microbiology Tehran Medical Sciences BranchIslamic Azad UniversityTehranIran

Objective:To assess the antimicrobial susceptibility pattern of ESKAPE pathogens from Neyshabur,Iran during ***:A total of 345 isolates including 62 Staphylococcus aureus(***),38 Enterobacter spp.(including 14 Enterobacter agglomerans,6 Enterobacter aerogenes and other 18 Enterobacter spp.),123 Enterococcus faecium,78 Klebsiella pneumonia,10 Pseudomonas aeruginosa and 34 Acinetobacter baumannii were *** antimicrobial susceptibility pattern of isolates was conducted with Kirby Bauer *** were analyzed with SPSS 20.0 software using F-and ***:Among *** isolates,the highest resistance was observed against nalidixic acid(81.35%)and cefixime(74.50%).Thirty-three(53.22%)*** isolates were cefoxitin resistant(methicillin-resistant ***).The majority of Enterobacter species was resistant to amikacin(100.00%)and cephalotin(66.60%).Most Enterococcus faecium isolates were resistant to nalidixic acid(89.43%)and amikacin(83.33%),but vancomycin-resistant enterococci isolates were not ***,among Klebsiella pneumonia,the highest resistance was observed to nalidixic acid(20.98%)and cotrimoxazole(28.39%).Furthermore,all Pseudomonas aeruginosa isolates were resistant to cefotaxime(100.00%)and majority to nitroforantoin(88.80%).Acinetobacter baumannii isolates showed the highest and the lowest resistance to cefotaxime(100.00%)and cefixime(88.71%),***:The prevalence of ESKAPE pathogens from northeast region was low,but majority of them exhibited high rate of antibiotic resistance to common used antimicrobial agents.

关键词： ESKAPE pathogens Disc diffusion Antimicrobial resistance Neyshabur Iran

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Effect of incorporating Elaeagnus angustifolia extract in PCL-PEG-PCL nanofibers for bone tissue engineering

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Frontiers of Chemical Science and Engineering 2019年第1期13卷 108-119页

作者： Vahideh R.Hokmabad Soodabeh Davaran Marziyeh Aghazadeh Effat Alizadeh Roya salehi Ali Ramazani Department of Chemistry University of Zanjan Zanjan Iran Drug Applied Research Center and Department of Medical Nanotechnology Faculty of Advanced Medical Science Tabriz University of Medical Sciences Tabriz Iran Stem Cell Research Center Tabriz University of Medical Sciences Tabriz Iran Oral Medicine Department of Dental Faculty Tabriz University of Medical Sciences Tabriz Iran Department of Medical Biotechnology Faculty of Advanced Medical Science Tabriz University of Medical Sciences Tabriz Iran

Plants have been used for medicinal purposes for thousands of years but they are still finding new uses in modem times. For example, Elaeagnus angustifolia (EA) is a medicinal herb with antinociceptive, anti-inflammatory, antibacterial and antioxidant properties and it is widely used in the treatment of rheumatoid arthritis and osteoarthritis. EA extract was loaded onto poly(ε-caprolactone)- poly(ethylene glycol)-poly(ε-caprolactone)(PCLPEG-PCL/EA) nanofibers and their potential applications for bone tissue engineering were studied. The morphology and chemical properties of the fibers were evaluated using Fourier transform infrared spectroscopy, field emission scanning electron microscopy, contact angle measurements and mechanical tests. All the samples had bead-free morphologies with average diameters ranging from 100 to 200 nm. The response of human cells to the PCL-PEGPCL/ EA nanofibers was evaluated using human dental pulp stem cells (hDPSCs). The hDPSCs had better adhesion and proliferation capacity on the EA loaded nanofibers than on the pristine PCL-PEG?PCL nanofibers. An alizarin red S assay and the alkaline phosphatase activity confirmed that the nanofibrous scaffolds induced osteoblastic performance in the hDPSCs. The quantitative real time polymerase chain reaction results confirmed that the EA loaded nanofibrous scaffolds had significantly upregulated gene expression correlating to osteogenic differentiation. These results suggest that PCL-PEG-PCL/ EA nanofibers might have potential applications for bone tissue engineering.

关键词： Elaeagnus angustifolia scaffold electrospinning human dental pulp stem cell tissue engineering

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Numerical simulation of incipient particle motion

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International Journal of Sediment Research 2020年第1期35卷 1-14页

作者： Ali Nasrollahi Ali Akbar salehi Neyshabouri Goodarz Ahmadi Masoud Montazeri Namin Civil Engineering Department Tarbiat Modares University Department of Mechanical and Aeronautical Engineering Clarkson University Civil Engineering Department University of Tehran

A two-dimensional(2 D) computational model for simulation of incipient sediment motion for noncohesive uniform and non-uniform particles on a horizontal bed was developed using the Discrete Element Method(DEM).The model was calibrated and verified using various experimental data reported in the literature and compared with different theories of incipient particle *** analysis was done and the effects of relevant parameters were *** addition to hydrodynamic forces such as drag,shear lift and Magnus force,the particle-particle interaction effects were included in the *** asymptotic critical mobility number was evaluated for various critical particle Reynolds numbers(R*) in the range of very small and very large R*.The obtained curve is classified into four *** was found that in the linear region,the drag force has the principal role on the initiation of ***,the critical mobility number is independent of particle diameter.A procedure for estimating the critical shear velocity directly from the information on particle diameter and roughness height was ***,the mechanism of incipient motion for the different regions was studied and the effect of different forces on the incipient particle motion was *** was found that the maximum effects of lift and Magnus forces were,respectively,less than ten and twenty percent of the total *** drag force,however,was typically the dominant force accounting for majority of the net hydrodynamic force acting on sediment particles at the onset of incipient motion.

关键词： Incipient motion Shields curve Numerical simulation Drag force Lift force Magnus force Discrete Element Method

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Gold nanocages in cancer diagnosis,therapy,and theranostics:A brief review

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Frontiers of Materials Science 2021年第4期15卷 494-511页

作者： Vahid ALIMARDANI Ghazal FARAHAVAR Sepide salehi Saeed TAGHIZADEH Moosa Rahimi GHIASI Samira Sadat ABOLMAALI Department of Pharmaceutical Nanotechnology School of PharmacyShiraz University of Medical SciencesShirazIran Department of Medical Biotechnology School of Advanced Medical Sciences and TechnologiesShiraz University of Medical SciencesShirazIran Laboratory of Basic Sciences Mohammad Rasul Allah Research TowerShiraz University of Medical SciencesShirazIran Center for Nanotechnology in Drug Delivery Shiraz University of Medical SciencesShirazIran

Regarding the increasing number of cancer patients,the global burden of this disease is continuing to *** a considerable improvement in the diagnosis and treatment of various types of cancer,new diagnosis and treatment strategies are ***,as an interesting and advanced field in medicine,is aimed to further advance both cancer diagnosis and *** nanocages(AuNCs),with hollow interiors and porous walls,have received a great deal of interest in various biomedical applications such as diagnosis,imaging,drug delivery,and hyperthermia therapy due to their special physicochemical characteristics including the porous structure and surface functionalization as well as optical and photothermal *** review is focused on recent developments in therapeutic and diagnostic and applications of AuNCs with an emphasis on their theranostic applications in cancer diseases.

关键词： gold nanocage cancer nanotechnology imaging theranostics drug delivery

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Theoretical and Experimental Study on the Adsorption and Desorption of Methane by Granular Activated Carbon at 25℃

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Journal of Natural Gas Chemistry 2007年第4期16卷 415-422页

作者： E.salehi V.Taghikhani C.Ghotbi E.Nemati Lay A.Shojaei Department of Chemical and Petroleum Engineering Sharif University of Technology TehranIran

A theoretical and experimental study was conducted to accurately determine the amount of adsorption and desorption of methane by various Granular Activated Carbon （GAC） under different physical conditions. To carry out the experiments, the volumetric method was used up to 500 psia at constant temperature of 25℃. In these experiments, adsorption as well as desorption capacities of four different GAC in the adsorption of methane, the major constituent of natural gas, at various equilibrium pressures and a constant temperature were studied. Also, various adsorption isotherm models were used to model the experimental data collected from the experiments. The accuracy of the results obtained from the adsorption isotherm models was compared and the values for the regressed parameters were reported. The results shows that the physical characteristics of activated carbons such as BET surface area, micropore volume, packing density, and pore size distribution play an important role in the amount of methane to be adsorbed and desorbed.

关键词： methane adsorption volumetric method activated carbon two-term TVFM isotherm

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Traction-assisted endoscopic mucosal resection for polypectomy in the large intestine

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World Journal of Gastroenterology 2010年第43期16卷 5462-5466页

作者： Bernhard Dauser Thomas Winkler Behrooz salehi Stefan Riss Franz Beer Friedrich Herbst Department of Surgery St. John of God Hospital Department of Surgery Medical University of Vienna Kerjaschki Laboratory of Pathology

AIM: To evaluate if traction-assisted endoscopic mucosal resection (TA-EMR) is feasible and if it enables en bloc resection of colorectal lesions. METHODS: Seven patients with a total of 12 colorectal adenomas were prospectively enrolled. All lesions were removed by TA-EMR: one hemostatic clip tied to a white silk suture was applied to the base of the lesion to allow traction through the working channel of the colonoscope. A conventional polypectomy snare was mounted over the suture and the lesion was pulled into the snare and resected in one piece. RESULTS: All 12 lesions (nine sessile) were resected en bloc with free lateral and vertical margins by using this novel technique, including five lesions (5/12, 41.6%) in less-accessible positions, where TA-EMR enabled complete visualization of the base before resection. Mean longest lesion and specimen sizes were 9 mm (range: 6-25 mm) and 11 mm in diameter (range: 7-17 mm),respectively. No serious procedure-related complications were observed. CONCLUSION: TA-EMR through the endoscope using a hemostatic clip and suture material is technically feasible. Visualization of colorectal lesions in less-accessible locations can be improved.

关键词： Traction-assisted Endoscopic mucosal resection Colon polyp Colonoscopy

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Clinical and pathological findings of concurrent poxvirus lesions and aspergillosis infection in canaries

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Asian Pacific Journal of Tropical Biomedicine 2013年第3期3卷 182-185页

作者： Kheirandish Reza Askari Nasrin salehi Mahmoud Department of Pathobiology Faculty of Veterinary MedicineShahid Bahonar University of Kerman Student of Veterinary Medicine Shahid Bahonar University of Kerman Department of Clinical Sciences Faculty of Veterinary MedicineShahid Bahonar University of Kerman

Objective:To investigate clinical,pathological and mycological findings in canaries,in which pox lesions and Aspergillus fumigatus(***)infection were observed ***:This study was performed on a breeding colony(about 100 canaries)affected by fatal wasting *** was undertaken on 10 severely affected canaries,and gross lesions were *** from internal organs displaying lesions were obtained for histopathological *** swap samples of internal organs of the all infected animals with lesions at necropsy were cultured in Sabouraud Dextrose Agar for mycological ***:At necropsy,caseous foci were determined in the lungs,on the air sacs,liver,spleen,*** of the eyelids,diffuse hemorrhages in the subcutaneous tissue with small papular lesions of the skin were other typical necropsy ***,pathognomonic eosinophilic intracytoplasmic inclusion bodies,which called Bollinger bodies,in both skin cells and vacuolated air way epithelial cells confirmed canary pox ***,histopathological examination of the white-yellowish caseous foci revealed necrotic granulomatous reaction consisting of macrophages,heterophil leukocytes and giant cells encapsulated with a fibrous *** the culture of the tissue samples,the formation of bluish green colonies confirmed *** ***:Canary pox has been known as the disease that can result in high losses in a short time,as a re-emerging disease that has not been present during recent years in canary flocks in ***,the current paper provides useful information to prevent misdiagnosed of canary pox disease which can cause secondary mycotic infection.

关键词： Canary Aspergilosis Diagnosis Pox infection Re-emerging disease Mycotic infections

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Qualitative Priority of Pollutants in Taleghan Catchment Using Analytical Hierarchy Process

Qualitative Priority of Pollutants in Taleghan Catchment Usi...

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International Conference on Environment and Industrial Innovation（ICEII 2011）

作者： mohammad Reza mohammad Shafiee Fatemeh Ghanbari Farham Amin Sharee Hadi salehi Faculty of Sciences Islamic Azad University - Najafabad Branch Najafabad Esfahan Iran

Water resources are considered as one of the main resources of supplying water for different uses including agriculture, drinking and industry. Due to the recent droughts, knowing and giving qualitative priority to the pollutants of these resources is one of the most important tasks in environmental management. The use of new models in water resources has an important role in the management of these resources. With a brief look at the condition of Iranian Taleghan catchment basin, we understand that the increase of population and raising the public welfare result in changing the land use and threat the natural resources and their reserves. This study aims to employ Expert Choice Software to give priority to different pollutants based on the type of the land use in the basin. In this research, Expert Choice Software was used to identify and classify pollutants in Taleghan catchment. This software works based on Analytical Hierarchy Process. The obtained results showed that sewage, agriculture, outdoor activities, industry, toll services, and restaurants respectively have the highest potential for polluting the basin. The employed model in this study can combine the comments and opinions together in great detail and high precision. The model can also determine the priority of effective variables on the pollution of water resources based on the kind of land use.

关键词： Pollutant Taleghan catchment basin Land use Analytical Hierarchy Process Expert Choice Software Water resources

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