检索结果-南通市图书馆

Can Campylobacter jejuni play a role in development of celiac disease? A hypothesis

World Journal of Gastroenterology 2007年第35期13卷 4784-4785页

作者： Behnam Sabayan Farzaneh Foroughinia mohammad hadi imanieh Student Research Center of Shiraz University of Medical Sciences ShirazIran Gastrohepatology Research Center Department of PediatricsShiraz University of Medical SciencesShirazIran

Celiac disease （CD） is an entropathy with malabsortive condition in which an allergic reaction to the cereal grain-protein （gluten） causes small intestine rnucosal injury. CD is a multifactorial disorder in which both genetic and environmental factors contribute to the disease development. Mechanisms have been described to explain the pathology of CD. T cells specific for multiple gluten peptides are found in virtually all patients. Generation of such a broad T cell response may be a prerequisite for disease development. CD is associated with multiple extraintestinal presentations, including neurological deficits. Recent studies have shown a significant correlation between anti-ganglioside antibodies and neurological disorders in patients with underlying CD. Gangliosides are glycosphingolipids which are abundant in nervous system and in other tissues including gastrointestinal tract. It is not known what triggers the release of anti-ganglioside antibodies in people with gluten sensitivity. But, the mechanism is likely to involve the intestinal immune system response to ingested gliadin, a component of wheat gluten. Studies showed that mechanisms different from gluten exposure may be implicated in antibody formation, and other environmental factors may also exist. In addition, considering the fact that genetic predisposition dysregulating mucosal immune responses in the presence of certain environmental triggers like gastrointestinal infections may be strong etiological factors for developing chronic intestinal inflammation including CD, the hypothesis raised in our mind that antiganglioside antibody formation in CD may play a role not only in development of neurological complications in celiac patients, but also in development of CD itself. As presence of Campylobacter jejuni in other diseases with antigangliosides antibody formation has been established, we propose the possible role of Campylobacter jejuni in development of CD in association with other genetic and

关键词： Celiac disease Gangliosides Campylobacter jejuni Molecular mimicry

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Comparison of different diagnostic methods in infants with Cholestasis

引用

World Journal of Gastroenterology 2006年第36期12卷 5893-5896页

作者： Seyed Mohsen Dehghani Mahmood Haghighat mohammad hadi imanieh Bita Geramizadeh Department of Pediatric Gastroenterology Gastroenterohepatology Research Center of Nemazee Hospital Shiraz University of Medical Sciences Shiraz Iran Department of Pathology Nemazee Hospital Shiraz University of Medical Sciences Shiraz Iran

AIM: To evaluate different methods in differentiating idiopathic neonatal hepatitis from biliary atresia. METHODS: Sixty-five infants with cholestatic jaundice and final diagnosis of idiopathic neonatal hepatitis and biliary atresia were studied prospectively from September 2003 to March 2006. A thorough history and physical examination were undertaken and the liver enzymes were examined. All cases underwent abdominal ultrasonography, hepatobiliary scintigraphy, and percutaneous liver biopsy. The accuracy, sensitivity, specificity and predictive values of these various methods were compared. RESULTS: There were 34 girls and 31 boys, among them 46 subjects had idiopathic neonatal hepatitis (age, 61 ± 17 d) and 19 had biliary atresia (age, 64 ± 18 d). The mean age at onset of jaundice was significantly lower in cases of biliary atresia when compared to idiopathic neonatal hepatitis cases (9 ± 13 d vs 20 ± 21 d; P = 0.032). The diagnostic accuracy of different methods was as follows: liver biopsy, 96.9%; clinical evaluation, 70.8%; ultrasonography, 69.2%; hepatobiliary scintigraphy, 58.5%; and liver enzymes, 50.8%.CONCLUSION: Our results indicate that clinical evaluation by an experienced pediatric hepatologist and a biopsy of the liver are considered as the most reliable methods to differentiate idiopathic neonatal hepatitis and biliary atresia.

关键词： Idiopathic neonatal hepatitis Biliary atresia Clinical evaluation Liver biopsy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Organisms causing spontaneous bacterial peritonitis in children with liver disease and ascites in Southern Iran

引用

World Journal of Gastroenterology 2006年第36期12卷 5890-5892页

作者： Mahmood Haghighat Seyed Mohsen Dehghani Abdolvahab Alborzi mohammad hadi imanieh Bahman Pourabbas Mehdi Kalani Department of Pediatric Gastroenterology Shiraz University of Medical Science Shiraz Iran Department of Professor Alborzi Clinical Microbiology Research Center Shiraz University of Medical Science Shiraz Iran

AIM： To determine the causative agents of spontaneous bacterial peritonitis （SBP） in children with liver disease and ascites in our center. METHODS： During a 2.5 year period, from September 2003 to March 2006, 12 patients with 13 episodes of SBP were studied. In all cases at the time of admission serum albumin and glucose, urinalysis and urine culture was performed. Analysis [white blood cell （WBC） count with differential, albumin, glucose], gram stain, culture by BACTEC method and antibiogram was done on ascitic fluids. Abdominal paracentesis was repeated after 48 h of antibiotic therapy for bacteriologic assay. The patients were followed for at least three months in a gastroenterology clinic. RESULTS： There were 7 girls （58%） and 5 boys （42%） with a median age of 5.2 years （range, 6 mo to 16 years）. All cases had positive ascitic fluid culture. Gram stain was positive in 5 （38.5%） of them. The isolated organisms were S. pneumoniae in 5 （38.5%）, E. coli in 2 （15.3%）, S. viridans in 2 （15.3%）, and K. pneumoniae, H. influenza, Enterococci, and nontypable Streptococcus each in one （7.7%）. All of them except Enterococci were sensitive to ciprofloxacin and ceftriaxone. All ascitic fluid cultures were negative after 48 h of antibiotic therapy. CONCLUSION： S. pneumoniae is the most common cause of SBP in the pediatric age group and we recommend a third generation cephalosporine （e.g., Ceftriaxlone or Cefotaxime） for empirical therapy in children with SBP.

关键词： Spontaneous bacterial peritonitis Children Cirrhosis Causes Empirical therapy

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Post-transplant lymphoproliferative disorder after liver transplantation: Incidence, long-term survival and impact of serum tacrolimus level

引用

World Journal of Gastroenterology 2017年第7期23卷 1224-1232页

作者： Ahad Eshraghian mohammad hadi imanieh Seyed Mohsen Dehghani Saman Nikeghbalian Alireza Shamsaeefar Frouzan Barshans Kourosh Kazemi Bita Geramizadeh Seyed Ali Malek-Hosseini Transplant Research Center Shiraz University of Medical Sciences Gastroenterohepatology Research Center Namazi Hospital

To investigate incidence and survival of post-transplant lymphoproliferative disorder (PTLD) patients after liver *** cross-sectional survey was conducted among patients who underwent liver transplantation at Shiraz Transplant Center (Shiraz, Iran) between August 2004 and March 2015. Clinical and laboratory data of patients were collected using a data gathering *** were 40 cases of PTLD in the pediatric age group and 13 cases in the adult group. The incidence of PTLD was 6.25% in pediatric patients and 1.18% in adult liver transplant recipients. The post-PTLD survival of patients at 6 mo was 75.1% ± 6%, at 1 year was 68.9% ± 6.5% and at 5 years was 39.2% ± 14.2%. Higher serum tacrolimus level was associated with lower post-PTLD survival in pediatric patients (OR = 1.07, 95%CI: 1.006-1.15, P = 0.032). A serum tacrolimus level over 11.1 ng/mL was predictive of post PTLD survival (sensitivity = 90%, specificity = 52%, area under the curve = 0.738, P = 0.035).CONCLUSIONIncidence of PTLD in our liver transplant patients is comparable to other centers. Transplant physicians may consider adjustment of tacrolimus dose to maintain its serum level below this cutoff point.

关键词： Post-transplant lymphoproliferative disorder Liver transplantation Survival Tacrolimus Epstein-Barr virus

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Stratigraphy of the Alveolina elliptica group from the Middle Eocene of Iran:Calibration with calcareous nannofossils biozones and description of Alveolina ozcani n. sp.

引用

Journal of Palaeogeography 2024年第1期13卷 54-79页

作者： Mehdi hadi Lorenzo Consorti Ali Bahrami mohammad Parandavar Saeed Khorramdel Department of Geology Faculty of SciencesUniversity of IsfahanIsfahanIran Institute of Marine Sciences(ISMAR-CNR) Area Science ParkBasovizza34149 TriesteItaly National Iranian Oil Company Exploration DirectorateSheikh Bahaei SquareTehranIran Department of Geology Faculty of ScienceFerdowsi University of MashhadMashhadIran

Precise taxonomy and the chronostratigraphic calibration of the Middle Eocene Alveolina from Central Iran is here undertaken from the Chah-Talkh section of the southern Sabzevar region(Central Iran). We have identified Alveolina kieli, Alveolina stercusmuris and Alveolina nuttalli along with the new species Alveolina ozcani n. sp. that we include into the Alveolina elliptica group. We have also found Nummulites uroniensis, Nummulites obesus and Nummulites cf. verneuili and associated calcareous nannofossils that look reliable to make thoughtful correlations with the Shallow Benthic Zones(SBZ). The foraminiferal biostratigraphy suggests an assignment to the upper part of the lower Lutetian-lower part of the middle Lutetian,SBZ13(Middle Eocene), further strengthened through the identification of the calcareous nannofossil NP14b-NP15b or CNE8-CNE10 biozones, providing a solid correlation with the global stratigraphic standards.

关键词： Alveolina Calcareous nannofossil Central neo-tethys Central Iran Middle Eocene Biostratigraphy

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Modelling and optimization of nonylphenol biosorption by novel lowcost magnetic Chlorella vulgaris

引用

Emerging Contaminants 2024年第3期10卷 170-180页

作者： Fatemeh Rahmani Nooshin Sajjadi mohammad hadi Dehghani Mozhgan Zaeimdar Environmental Science and Technology Department Marine Science and Technology FacultyNorth Tehran BranchIslamic Azad UniversityTehranIran Department of Environmental Health Engineering School of Public HealthTehran University of Medical SciencesTehranIran Center for Solid Waste Research Institute for Environmental ResearchTehran University of Medical SciencesTehranIran

Discharging untreated wastewater causes environmental *** research examined the efficiency of removal and the adsorption process of Emerging Contaminant nonylphenol(NP)using magnetic Chlorella vulgaris(M-Chlorella vulgaris).The characterization of M-Chlorella vulgaris involved XRD,FESEM,EDS-Mapping,BET,FTIR,and VSM *** impact of four different parametersdpH,MChlorella vulgaris dose,initial concentration of NP,and contact time on the biosorption process was *** model and optimize the study while minimizing costs and the number of experiments,Response Surface Methodology(RSM)with Central Composite Design(CCD)was *** to the findings,the quadratic model with adjusted R^(2)=0.96 was the best fitted among the other *** pH=3.5,dosage=2.5 g/l,NP concentration=4 mg/l,and reaction time=70 min,which are the optimal parameters,the maximum removal effectiveness was about 91%.The Langmuir model(R^(2)=0.998)and pseudo-second-order model(R^(2)=0.997)exhibited the best fits for the adsorption isotherm and kinetic studies,*** characteristics of M-Chlorella vulgaris were determined to facilitate a spontaneous nature,and thermodynamic experiments indicated that the process of adsorption of nonylphenol is *** inexpensiveness and availability of adsorbent,suitable efficiency in the biosorption of pollutant and magnetic collection of pollutant from the aquatic environment can be mentioned as the advantages of this process.

关键词： RSM-CCD Nonylphenol Biosorption Algea Emerging contaminants M-Chlorella vulgaris

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Black radish root extract alleviates sodium valproate-induced liver damage via inhibiting mitochondrial membrane potential collapse and oxidative stress in mice

引用

Asian Pacific Journal of Tropical Biomedicine 2024年第7期14卷 298-306页

作者： mohammad hadi Zarei Sami Akbulut Maryam Zafari Elham Saghaei Zahra Lorigooini Hossein AminiKhoei Somaye Khosravi Elham Bijad Medical Plants Research Center Basic Health Sciences InstituteShahrekord University of Medical SciencesShahrekordIran Department of Liver Transplant Institute and Biostatistics Inonu University Faculty of Medicine44280MalatyaTurkey Student Research Committee Shahrekord University of Medical SciencesShahrekordIran Physiology and Pharmacology Department School of MedicineShahrekord University of Medical SciencesShahrekordIran Department of Anatomical Sciences School of MedicineShahrekord University of Medical SciencesShahrekordIran

Objective:To explore the effect of black radish(Raphanus sativus *** niger)root extract on liver enzymes,oxidative stress,and histopathological alterations in mice with sodium valproate-induced ***:Thirty-two mice were divided into four groups:the control group received drinking water by gavage,the second group was administered with 100 mg/kg of sodium valproate,the third group received 300 mg/kg of black radish root extract,and the fourth group was given both sodium valproate(100 mg/kg)and black radish root extract(300 mg/kg).After 28 days,the mice were euthanized,and serum levels of aspartate aminotransferase(AST),alanine aminotransferase(ALT),and alkaline phosphatase(ALP),along with liver malondialdehyde(MDA),reactive oxygen species(ROS),mitochondrial parameters,tumor necrosis factor-alpha(TNF-α)gene expression,and histopathological changes were ***:Sodium valproate caused hepatic damage in mice,characterized by elevated serum levels of liver enzymes,increased MDA and ROS levels and TNF-αgene expression,as well as histopathological *** black radish root extract significantly alleviated sodium valproate-caused hepatic injury by decreasing the serum levels of ALT and AST,MDA,ROS,TNF-αgene expression,as well as mitochondrial impairment,but did not have a significant effect on sodium valproate-induced histopathological ***:The black radish root extract demonstrates protective effects against sodium valproate-induced liver injury,possibly through mitigating oxidative stress,mitochondrial impairment,and inflammatory mediator expression.

关键词： Black radish Raphanus sativus Sodium valproate Hepatotoxicity Oxidative stress Anti-inflammation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hydrogel-based materials as antibacterial agents and super adsorbents for the remediation of emerging pollutants:A comprehensive review

引用

Emerging Contaminants 2024年第3期10卷 46-67页

作者： Shabnam Ahmadi Sina Pourebrahimi Alhadji Malloum Majid Pirooz Christian Osagie Soumya Ghosh Muhammad Nadeem Zafar mohammad hadi Dehghani Department of Environmental Health Engineering Faculty of Medical SciencesTarbiat Modares UniversityPO Box 14115-111TehranIran Department of Chemical and Materials Engineering Concordia University7141 Sherbrooke Street WestMontrealQuebecH4B 1R6Canada Department of Physics Faculty of ScienceUniversity of MarouaPO Box 46MarouaCameroon Department of Chemistry University of the Free StatePO Box 3399300BloemfonteinSouth Africa Research and Development Division Pad Jam Polymer Development Company(PJPC)and Department of Chemical EngineeringUniversity of Isfahan81746-73441IsfahanIran Stochastics and Its Applications Brandenburg University of Technology Cottbus-SenftenbergPlatz der Deutschen Einheit 103046CottbusGermany Natural and Medical Sciences Research Center University of NizwaNizwa616Oman Department of Chemistry University of Gujrat50700GujratPakistan Department of Environmental Health Engineering School of Public HealthTehran University of Medical SciencesTehranIran Center for Solid Waste Research Institute for Environmental ResearchTehran University of Medical SciencesTehranIran

Hydrogels have various potential applications due to their unique characteristics and recently,hydrogels have been utilized as adsorbents in wastewater treatment because of their ability to remove contaminants from *** strong hydrogels with high adsorption capabilities is crucial for effective wastewater *** and researchers are working to improve the properties of hydrogels by incorporating inorganic elements into polymer networks,which further reduces the costs as well as simplifies their *** polymers like starch and alginate are widespread due to their economic and biological advantages,such as biodegradability,biocompatibility,reduced toxicity,environmental friendliness,and low *** adsorption of pollutants onto hydrogels as well as their use as antimicrobial agents has garnered significant *** review paper summarizes the latest studies on using hydrogels as adsorbents to remove endocrine-disrupting chemicals(EDCs),persistent organic pollutants(POPs),and other emerging pollutants from water environments along with their use as antimicrobial *** the first step,different classes of hydrogels and different characterization techniques have been *** antimicrobial potential of hydrogels is elaborated to understand how these hydrogels can be a potential candidate for such *** discussing the adsorption application of hydrogels,different isothermal,kinetics and thermodynamics models have been discussed to highlight the mechanism and nature of forces involved in adsorption of *** different simulations such as DFT and MD have been discussed to get more holistic understanding of pollutants adsorption onto hydrogels.A limited number of studies have utilized other techniques such as Monte Carlo simulations and computational fluid dynamics(CFD)so it is important to explore a variety of computational methods to gain a comprehensive understanding of the adsorption process o

关键词： Hydrogel Emerging pollutant Adsorption Water and wastewater Monte Carlo simulations Antimicrobial activity

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Long-term follow-up of intravesical abobotulinumtoxinA (Dysport®) injections in women with idiopathic detrusor overactivity

引用

Asian Journal of Urology 2024年第1期11卷 93-98页

作者： mohammad Sajjad Rahnama'i Amin Bagheri Elham Jahantabi Hanieh Salehi-Pourmehr hadi Mostafaei Brigitte Schurch Aida Javan Balegh Marand Sakineh Hajebrahimi Department of Urology St.Elisabeth-Tweesteden Hospital Tilburgthe Netherlands Research Center for Evidence-based Medicine Iranian EBM Centre:A Joanna Briggs Institute(JBI)Center of ExcellenceTabriz University of Medical SciencesTabrizIran Urology Department Faculty of MedicineTabriz University of Medical SciencesTabrizIran Department of Urology Comprehensive Cancer CenterMedical University of ViennaViennaAustria Service de Neuroréhabilitation CHUVLausanneSwitzerland Society of Urological Research and Education(SURE) Heerlenthe Netherlands

Objective:Only a few numbers of studies have been published on the use of abobotulinumtoxinA(Dysport®)in idiopathic detrusor overactivity(IDO).This study reported the long-term follow-up of women with IDO who were treated with intravesical Dysport®***:Two hundred and thirty-six patients with IDO who had failed first-line conservative and antimuscarinic therapy received 500-900 units of Dysport®between April 2014 and July *** patients were followed up for 5 years after their initial injection and interviewed on the ***:A total of 236 women with IDO aged from 18 years to 84 years(mean±standard deviation:49.6±15.9 years)were included in our *** median follow-up time for patients was 36.5(range:10-70)months,and the median recovery time after injection was 18.5(range:0-70)months.A total of 83(35.2%)patients stated that they had subjective improvement of their symptoms whereas 84(35.6%)patients did not report any improvement in *** initial International Consultation on Incontinence Questionnaire Overactive Bladder mean score was 6.9(standard deviation 3.4).There was a positive association between the median recovery time and the components of the International Consultation on Incontinence Questionnaire Overactive Bladder ***:In a sub-population of overactive bladder patients with IDO who have failed first-line therapy,a single intravesical Dysport®injection can resolve patient symptoms completely or reduce the symptoms to an acceptable level that can be controlled with antimuscarinics or re-injection on demands.

关键词： AbobotulinumtoxinA Dysport Intravesical ldiopathic Detrusor overactivity

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

New-fashioned solitons of coupled nonlinear Maccari systems describing the motion of solitary waves in fluid flow

引用

Journal of Ocean Engineering and Science 2024年第4期9卷 353-363页

作者： Tarikul Islam Ali Akbar hadi Rezazadeh Ahmet Bekir Department of Mathematics Hajee Mohammad Danesh Science and Technology UniversityDinajpurBangladesh Department of Applied Mathematics University of RajshahiBangladesh Faculty of Modern Technologies Engineering Amol University of Special Modern TechnologiesAmolIran Neighbourhood of Akcaglan Imarli StreetNo.28/4Eskisehir 26030Turkey

The Schrodinger equation type nonlinear coupled Maccari system is a significant equation that flourished with the wide-ranging arena concerning fluid flow and the theory of deep-water waves,physics of plasma,nonlinear optics,*** exploit the enhanced tanh approach and the rational(G/G)-expansion process to retrieve the soliton and dissimilar soliton solutions to the Maccari system in this *** suggested systems of nonlinear equations turn into a differential equation of single variable through executing some operations of wave variable ***,with the successful implementation of the advised techniques,a lot of exact soliton solutions are *** obtained solutions are depicted in 2D,3D,and contour traces by assigning appropriate values of the allied unknown *** diverse graphical appearances assist the researchers to understand the underlying processes of intricate phenomena of the leading *** individual performances of the employed methods are praise-worthy which justify further application to unravel many other nonlinear evolution equations ascending in various branches of science and engineering.

关键词： Rational(G'/G)-expansion method Coupled nonlinear schrodinger equations Soliton Improved tanh method Exact solutions

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：