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Prognostic value of cortisol and thyroid function tests in poisoned patients admitted to toxicology ICU

World Journal of Emergency Medicine 2018年第1期9卷 51-55页

作者： Shahin Shadnia Nasim Zamani Hossein Hassanian-Moghaddam Hamed Shafaroodi Mina Padandar mohammad hasan rezaeizadeh Toxicological Research Center Department of Clinical ToxicologyLoghman Hakim HospitalShahid Beheshti University of Medical Sciences Excellence Center of Clinical Toxicology Iranian Ministry of Health Pharmaceutical Sciences Branch Islamic Azad University(IAUPS)

BACKGROUND: Prognostic value of cortisol and thyroid function tests(TFTs) has previously been evaluated in medical ICUs. We aimed to evaluate prognostic efficacy of cortisol and TFTs in critically ill poisoned patients admitted to toxicology intensive care unit(ICU).METHODS: In a prospective study of consecutively enrolled subjects admitted to the toxicology ICU, lab analyses included TFTs(total T3 and T4 as well as TSH) and cortisol levels drawn between 8 am–10 am during period of the first 24 hours post-ingestion/exposure. Simplified Acute Physiology Score Ⅱ(SAPS Ⅱ) and Acute Physiology and Chronic Health Evaluation Ⅱ(APACHE Ⅱ) were recorded. All scores were compared to detect the best prognostic factor. Type of poisoning was also ***: In 200 patients evaluated, 129 were male and mean age was 31 years. In general, SAPS Ⅱ, T4, and cortisol could prognosticate death. After regression analysis, only cortisol had such efficacy(P=0.04; OR=1.06; 95%CI=1.05–1.08; cut-off=42 μg/d L; sensitivity=70%; specificity=82%). Between aluminium phosphide(ALP)-and non ALP-poisoned patients, level of consciousness, mean arterial pressure, and cortisol level could prognosticate death in ALP poisoning(all Ps<0.001 in both uni and multivariate analyses). Median(interquartile range; IQR) GCS was 7(6, 10) and 15(8, 15) in non-ALP and ALP-poisoned patients(P<0.003). SAPS Ⅱ and APACHE Ⅱ could not prognosticate death at ***: Cortisol best prognosticated outcomes for subjects admitted to the toxicology ICU. Its level is higher in ALP-poisoned patients probably due to the higher stress while they remain conscious till the final stages of toxicity and are aware of deterioration of their clinical condition or may be due to their significantly lower blood pressures.

关键词： Prognosis Intensive care unit Cortisol Thyroid function tests Poisoning

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Sensitivity of optimal double-layer grid designs to geometrical imperfections and geometric nonlinearity conditions in the analysis phase

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Frontiers of Structural and Civil Engineering 2024年第8期18卷 1209-1224页

作者： Amirali rezaeizadeh Mahsa ZANDI Majid ILCHI GHAZAAN School of Civil Engineering Iran University of Science and TechnologyTehran 16846-13114Iran

This study focuses on exploring the effects of geometrical imperfections and different analysis methods on the optimum design of Double-Layer Grids(DLGs),as used in the construction industry.A total of 12 notable metaheuristics are assessed and contrasted,and as a result,the Slime Mold Algorithm is identified as the most effective approach for size optimization of *** evaluate the influence of geometric imperfections and nonlinearity on the optimal design of real-size DLGs,the optimization process is carried out by considering and disregarding geometric nonlinearity while incorporating three distinct forms of geometrical imperfections,namely local imperfections,global imperfections,and combinations of *** light of the uncertain nature of geometrical imperfections,probabilistic distributions are used to define these imperfections randomly in direction and *** results demonstrate that it is necessary to account for these imperfections to obtain an optimal ***’s worth noting that structural imperfections can increase the maximum stress ratio by up to 70%.The analysis also reveals that the initial curvature of members has a more significant impact on the optimal design of structures than the nodal installation error,indicating the need for greater attention to local imperfection issues in space structure construction.

关键词： double-layer grid sizing optimization metaheuristic algorithms geometrical imperfections analysis approach

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Effect of fin attachment on thermal stress reduction of exhaust manifold of an off road diesel engine

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Journal of Central South University 2017年第3期24卷 546-559页

作者： Ali Akbar Partoaa Morteza Abdolzadeh Masoud rezaeizadeh Department of Mechanical Engineering Graduate University of Advanced Technology Kerman Iran

The effect of fin attachment on the thermal stress reduction of exhaust manifold of an off road diesel engine(Komatsu HD325-6) was *** doing this,coupled thermo-fluid-solid analysis of exhaust manifold of the off road diesel engine was carried *** thermal analysis,including thermal flow,thermal stress,and the thermal deformation of the manifold was *** flow inside the manifold was simulated and then its properties including velocity,pressure,and temperature were *** flow properties were transferred to the solid model and then the thermal stresses and the thermal deformations of the manifold under different operating conditions were ***,based on the predicted thermal stresses and thermal deformations of the manifold body shell,two fin types as well as body shell thickness increase were applied in the critical induced thermal stress area of the manifold to reduce the thermal stress and thermal *** results of the above modifications show that the combined modifications,*** thickness increase and the fin attachment,decrease the thermal stresses by up to 28% and the contribution of the fin attachment in this reduction is much higher compared to the shell thickness increase.

关键词： manifold exhaust simulation modification thermal stress deformation diesel engine

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Liver tonics:review of plants used in Iranian traditional medicine

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Asian Pacific Journal of Tropical Biomedicine 2015年第3期5卷 170-181页

作者： Tahmineh Akbarzadeh Reyhaneh Sabourian Mina Saeedi Hossein rezaeizadeh Mahnaz Khanavi mohammad Reza Shams Ardekani Department of Medicinal Chemistry Faculty of PharmacyTehran University of Medical Sciences Persian Medicine and Pharmacy Research Center Tehran University of Medical Sciences Medicinal Plants Research Center Tehran University of Medical Sciences Faculty of Traditional Medicine Tehran University of Medical Sciences Department of Pharmacognosy.Tehran University of Medical Sciences

Considering the fact that liver is one of the most important organs in our body,it deserves special attention and *** various recommended supplements,complementary and alternative medicines particularly herbal remedies have received much attention owing to their truly healing *** review profits from Iranian traditional medicine and presents advantageous herbal guide directions for liver *** to credible Iranian medical literature such as Al Qanun Fil ***-Havi and Makhzan-al-Aadvia.a wide spectrum of plants have been found to be useful for cleansing and protecting the *** herbs such as ghafes(Agrimonia eupatoria),kasni(Cichorium intybus),anar(Punica granatum),darchin(Cinnamomum zeylanicum),za'feran(Crocus sativus),gole-sorkh(Rosa damascena) and zereshk(Berberis vulgaris) appeared to get strong consideration and were well documented as outstanding liver *** conducted a comprehensive review of available Iranian medical resources such as scientific information database and medical sciences databases which cover all in vitro and in vivo studies of medicinal plants as liver tonics and hepatoprotcctive *** survey was accomplished using multiple databases including PubMed,ISI web of knowledge,and Google Scholar.

关键词： Iranian traditional medicine Liver tonic Hepatoprotective agents Herbal medicine

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Efficacy of a traditional Persian medicine preparation for radiation-induced xerostomia:a randomized,open-label,active-controlled trial

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Journal of Integrative Medicine 2017年第3期15卷 201-208页

作者： Ghazaleh Heydarirad Hossein rezaeizadeh Rasool Choopani Seyed Hamdollah Mosavat Ahmad Ameri Department of Traditional Medicine School of Traditional Medicine Shahid Beheshti University of Medical Sciences Tehran 15167-45811 Iran Department of Traditional Medicine School of Traditional Medicine Tehran University of Medical Science Tehran 16687-53961 Iran Research Center for Traditional Medicine and History of Medicine Shiraz University of Medical SciencesShiraz 71356-44144 Iran Essence of Parsiyan Wisdom Institute Traditional Medicine and Medicinal Plant Incubator Shiraz University of Medical Sciences Shiraz 71356-44144 Iran Department of Radiation Oncology Imam Hossein Hospital Shahid Beheshti University of Medical SciencesTehran 19946-15611 Iran

BACKGROUND： Xerostomia is one of the most common side effects of radiation therapy among patients with head and neck cancers （HNC）. However, conventional medicine lacks an effective treatment for radiation-induced xerostomia. OBJECTIVE： Synthesizing the traditional use ofAIcea digitata and Malva sylvestris with their known beneficial effects from recent studies, we evaluated the efficacy of the herbs in the quality of life （QOL） of HNC patients with radiation-induced xerostomia. DESIGN, SETTING, PARTICIPANTS AND INTERVENTIONS： This study is a randomized, double-arm, open-label active-controlled clinical trial. We evaluated the effect ofA. digitata and M. sy/vestris on QOL of HNC patients with radiation-induced xerostomia compared with Hypozalix （artificial saliva）. Patients were enrolled from the Imam Hossein Hospital＇s oncology clinic in Shahid Beheshti University of Medica Sciences. Tehran, Iran. MAIN OUTCOME MEASURES： Primary outcome measures in this trial were changes in patients＇ QOL assessed by the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire, Head and Neck Module （EORTC QLQ-H＆N 35）. RESULTS： Between-group analysis showed that the intervention group patients obtained significantly lower （better） total EORTC QLQ-H＆N 35 scores as compared to the control group at the end of the intervention period （P = 0.007）. Mean scores of dry mouth of EORTC QLQ-H＆N 35 was also significantly lower （better） in the intervention group as compared to the control group （P = 0.017）.

关键词： xerostomia medicine Persian traditional hollyhocks common mallow cancer

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Lavender and dodder combined herbal syrup versus citalopram in major depressive disorder with anxious distress: A double-blind randomized trial

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Journal of Integrative Medicine 2020年第5期18卷 409-415页

作者： Toktam Sadat Firoozeei Majid Barekatain Mehrdad Karimi Arman Zargaran Shahin Akhondzadeh Hossein rezaeizadeh Deportment of Persion Medicine School of Persian MedicineTehron University of Medical SciencesTehran ***Iran Department of Psychiatry 5chool of Medicine.lsfahan University of Medical Sctences.Isfahan ***Iran Depertment of Trditioniod Phormay School of Persion Medicine.Tehran Untiversity of Medical Sciences.Tehran *** Iran Pschitric Research Center Roozbeh HospitalTehran University of Medical Sctences.Tehran ***Iran

Background: Major depressive disorder(MDD) accompanied by anxious distress is a chronic and disabling disorder. Its conventional drug therapies often have low patient compliance due to drug-related side effects. In Persian medicine, lavender-dodder syrup is one formula often recommended for such ***: This study compares the effects of lavender-dodder syrup to the standard drug, citalopram, for treating MDD with anxious ***, setting, participants and intervention: This six-week, double-blind, randomized, clinical trial was carried out in a psychiatric outpatient clinic. During the six-week intervention period, patients in citalopram group received citalopram tablets 20 mg/d plus 5 mL placebo syrup every 12 h;patients in group B received placebo tablets once daily plus 5 mL of lavender-dodder herbal syrup every 12 *** outcome measures: Primary outcome measures, depression and anxiety, were evaluated using the Hamilton Depression/Anxiety Rating Scales, and were scored at the beginning of the study and at weeks three and six. Secondary outcome measures including response to treatment and remission rates were also compared between the two ***: Fifty-six participants with MDD and anxious distress were randomly assigned to two *** depression scores significantly decreased in citalopram and herbal groups at weeks three and six(time effect: P < 0.001), although the observed changes were not significantly different between the groups(intervention effect: P = 0.61). Mean anxiety scores were not significantly different between the two groups at week three(P = 0.75). However, at the end of week six, the observed decrease was significantly higher in the herbal syrup group than the citalopram group(intervention effect: P = 0.007).Conclusion: The herbal syrup is an effective and tolerable supplement for treating MDD with anxious *** registration number: IRCT2016102430459 N1 on Iranian Registry of Clinical Trials.

关键词： Persian medicine Traditional medicine Anxiety Depression Phytotherapy Lavender Dodder Citalopram

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Therapeutic effects of acupuncture on blood glucose level among patients with type-2 diabetes mellitus: A randomized clinical trial

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Journal of Traditional Chinese Medical Sciences 2019年第1期6卷 101-107页

作者： Amir Hooman Kazemi Wei Wang Yanping Wang Faezeh Khodaie Hossein rezaeizadeh School of Persian Medicine Tehran University of Medical SciencesTehranIran School of Chinese Medicine Beijing University of Chinese MedicineBeijing 100029China School of Acupuncture Moxibustion and TuinaBeijing University of Chinese MedicineBeijing 100029China

Objective:To compare the therapeutic effects of acupuncture with sham acupuncture on levels of fasting plasma glucose (FPG) and glycated hemoglobin (HbA1c) among patients with type-2 diabetes mellitus (T2DM) under treatment with ***:Eighty participants with T2DM were allocated randomly to treatment (n =40) and control (n =40) *** addition to metformin therapy,patients in the acupuncture group received acupoint stimulation with even manipulation at 15 acupoints,and needles were retained for 20 *** sham-acupuncture group was treated with very small needles inserted at a very shallow depth (3-5 mm) without manipulation at non-acupoints 1 cm around the actual acupuncture *** groups were treated for 14 sessions during 10 weeks of *** FPG level was measured before treatment as well as after 1,2,4,6 and 12 weeks of *** HbA1c percentage was assessed once before treatment and once 12 weeks after treatment ***:Levels of FPG and HbA1c in both groups were reduced significantly in comparison with baseline measurements (both P <.01).However,acupuncture treatment led to a significant reduction in the FPG level as compared with sham acupuncture after 4 weeks or 10 sessions of treatment [mean difference (MD) =10.18,95% confidence interval (CI) =1.74 to 18.6,P =.019],after 6 weeks or 12 sessions of treatment (MD =10.53,95% CI =2.22 to 18.83,P =.014) and after 12-week follow-up (MD =8.8,95% Cl =0.66 to 16.94,P =.034).Acupuncture treatment reduced the HbA1c level significantly in comparison with that in the shamacupuncture group (MD =0.27,95%Cl =0.08 to 0.47,P =.007).Conclusion:Our study revealed that acupuncture (as a type of Chinese therapy) combined with metformin (as a conventional hypoglycemic medication) had a greater effect on glycemic control than that elicited in the placebo control ***,acupuncture could be used as adjuvant therapy among patients with T2DM.

关键词： Diabetes mellitus type 2 Acupuncture Glycated hemoglobin

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