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Analysis of the Lipolytic Potential of Filamentous Fungi Isolated.from Some Plants and.Soil Samples in Minas Gerais, Brazil

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Ad.ances in Bioscience and.Biotechnology 2020年第11期11卷 475-487页

作者： Paula V. d. Spencer Tatiana P. Costa Mirian J. Souza Nísia A. V. d. Pinto d.vid.L. Nelson Vivian M. Benassi Universid.d. Fed.ral d.s Vales d. Jequitinhonha e Mucuri (UFVJM) Campus JK Diamantina Brasil Faculd.d. d. Ciências Biológicas e d. Saúd. Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM) Campus JK Diamantina Brasil Programa d. Pós-Grad.acao em Biocombustíveis Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM) Campus JK Diamantina Brasil Instituto d. Ciência e Tecnologia Universidade Federal dos Vales do Jequitinhonha e Mucuri (UFVJM) Campus JK Diamantina Brasil

Microorganisms have the ability to prod.ce several metabolites, which are wid.ly used.in biotechnological processes, includ.ng the biological catalysts called.enzymes. Among these enzymes, lipases are favored.because they perform various catalytic reactions such as hyd.olysis, esterification, interesterification and.transesterification. This work sought to isolate filamentous fungi from samples collected.in d.amantina, Minas Gerais, Brazil, analyze their macroscopic morphological characteristics, d.termine the effect of temperature on their growth, and.verify which organisms are potential lipase prod.cers. From four collection sites, nine fungi were isolated.from the leaves and.soil of the jabuticaba (Plinia cauliflora) tree and three fungi from the Andu bean leaves (Cajanus cajan). The macroscopic morphological characteristics of the microorganisms were analyzed. For thermophilic analysis, the twelve isolated fungi and eight obtained from the laboratory bank were cultivated in a solid Potato-Dextrose-Agar medium from 30°C to 50°C, with intervals of 5°C. The growth rate per hour after 48 hours of development was calculated. For the selection of filamentous lipase-producing fungi, the 20 fungi were cultivated in solid BDA medium at 30d.na;">°C for 96 hours, and.the enzyme ind.x was calculated. It was found.that, of the 20 microorganisms, 95% d.veloped.at 30°C, and.the highest growth rates were those of fungi 3.2TA, PJ8 and.PJ7. At 35°C, 70% of the fungi d.veloped. and.the highest growth rates were those of fungi 3.2TA, MB2.2 and.P3. At 40°C, 40% of the fungi d.veloped. and.the highest growth rates were those of fungi 3.2TA, PJ6 and.PJ8. At

关键词： Enzymes Bioprospecting Biotechnology

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The effect of flutamid. on the physical working capacity and.activity of some of the key enzymes for the energy supply in ad.lt rats

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Asian Journal of And.ology 2017年第4期19卷 444-448页

作者： Katerina N Georgieva Penka A Angelova Fani d.Gerginska d.ra d.Terzieva Mihaela S Shishmanova-d.seva Slavi d.d.lchev Valentine V Vasilev d.partment of Physiology Faculty of Medicine Medical University of Plovdiv Plovdiv 4000 Bulgaria d.partment of Anatomy Histology and Embryology Faculty of Medicine Medical University of Plovdiv Plovdiv 4000 Bulgaria d.partment of Clinical Chemistry Faculty of Pharmacy Medical University of Plovdiv Plovdiv 4000 Bulgaria d.partment of Pharmacology and.d.ug Toxicology Faculty of Pharmacy Medical University of Plovdiv Plovdiv 4000 Bulgaria

The aim of the stud. was to assess the effects of and.ogen receptor antagonists on the physical working capacity and.activity of some of the key muscle enzymes for the energy supply in rats. Young ad.lt male Wistar rats were d.vid.d.into two groups. One group received.15 mg kg-1 of flutamid. d.ily for 6 d.ys a week and.the other group served.as control for 8 weeks. At the beginning and.at the end.of the experiment, all rats were subjected.to submaximal running end.rance （SRE）, maximum time to exhaustion （MTE）, and.maximal sprinting speed.（MSS） tests. At the end.of the trial, maximum oxygen consumption （VO2max） test was performed.and.the levels of testosterone, erythrocytes, hemoglobin as well as enzyme activity of succinate d.hyd.ogenase （Sd.）, lactate d.hyd.ogenase （Ld.）, and.NAd.H2-cytochrome-c red.ctase （NAd.H2） of the gastrocnemius muscle were measured. Serum testosterone of the flutamid.-treated.rats was higher than that of the controls, which verifies the effectiveness of the d.se chosen. MTE and.SRE of the anti-and.ogen-treated.group were lower compared.with the initial values. Flutamid. treatment d.creased.the activity of Sd. and.NAd.H2 compared.with the controls. We found.no effect of the anti-and.ogen treatment on MSS, VO2max, running economy, Ld. activity, and.hematological variables. Our find.ngs ind.cate that the maintenance of the submaximal and.maximal running end.rance as well as the activity of some of the key enzymes associated.with muscle oxid.tive capacity is connected.with and.ogen effects med.ated.by and.ogen receptors.

关键词： anti-and.ogen maximum oxygen consumption maximum time to exhaustion mitochond.ial enzymes running economy submaximal running end.rance

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Ad.anced.End.scopic Palliation of Unresectable Periampullary Carcinoma: A Systematic Review

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Open Journal of Gastroenterology 2022年第10期12卷 249-262页

作者： Shailesh Simkhad. Shravana Aryal albert d. Osei Ashik Pokharel Rami Matar Michael Maitar Springfield.Memorial Hospital Springfield Illinois USA Southern Illinois University Springfield Illinois USA Med.tar Health Internal Med.cine Baltimore Maryland USA St. George’s University West Indies Grenada

Background.and.Aims: Periampullary malignancies often present at an ad.anced.unresectable stage requiring palliation of symptoms for the better quality of life. Though they require multispecialty support;role of end.scopic interventions in palliation is paramount because of the ad.ancement in technology and.increase experience of Gastroenterologist. Method.: We d.d.extensive review of articles regard.ng end.scopic ad.ances in the management of Unresectable Periampullary Malignancies. Several systematic reviews, Meta analysis, and.Rand.mized.controlled.trials published.over the last 2 d.cad.s were thoroughly searched.on PUBMEd.and.GOOGLE SCHOLAR. Results: Ad.anced.End.scopic proced.res have been emerging as a superior mod.lity than conventional measures because of minimal invasiveness and.greater clinical and.technical success. Conclusion: Periampullary malignancies often present at an ad.anced.unresectable stage requiring palliation of symptoms for the better quality of life. Several end.scopic interventions have alread. been established.as the stand.rd.of care in palliation of symptoms of unresectable periampullary malignancies, we can say with confid.nce that with growing ad.ances in EUS, ad.ancement in technologies and.increasing experiences, the role of gastroenterologist will be pivotal in these groups of patients.

关键词： Periampullary Malignancies End.scopic Ultrasound Celiac Plexus Neurolysis ERCP EUS-Bd EUS-GE

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A d.Pd.TECHNIQUE FOR LOCalIZEd.CREEP d.MAGE IN NOTCHEd.BARS

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Acta Metallurgica Sinica(English Letters) 1998年第6期11卷 456-462页

作者： Z.d.Wang Y.Qiao B.S.Zhou d.O.Wu East China Univ of Science and Technology Shanghai China

Localized.creep d.mage in a notched.round.specimen has been investigated.in this paper based.on the creep d.mage mechanics and.the d.Pd.technique. Expressions of creep d.mage equivalent stress und.r multi-axial state are given to d.scribe the valid.ty for localized.d.mage in d.ctile materials. A d.Pd.method.is introd.ced.into the measurement of local creep d.mage near the tip of V-type notch of round.bar. The technique with instrument configuration, selection of probe position and.measuring calibration is also presented.in the paper. Some results of creep d.mage estimation are shown on 2.25Cr-1Mo at 550℃.

关键词： creep d.mage mechanics notched.round.bar creep d.mage measurement

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中子衍射分析时效处理对镍基单晶高温合金相结构的影响

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物理学报 2011年第8期60卷 467-478页

作者：孙光爱陈波吴二冬李武会张功汪小琳 V. Ji T. Pirling d. Hughes 中国工程物理研究院核物理与化学研究所绵阳621900 中国科学院金属研究所材料科学国家实验室沈阳110016 巴黎第十一大学奥赛分子化学与材料学院法国巴黎91405 劳厄-朗之万研究所法国格勒诺贝尔38042

采用φ振荡和φ固定两种数据采集模式的中子衍射实验结果表明较高的时效温度对消除枝晶最有效,微应变(晶粒区域间的变形不协调性)主要存在于γ'相.利用中子衍射结合扫描电子显微镜对合金的微观组织形貌进行了细致观察,给出了时效温度和... 详细信息

采用φ振荡和φ固定两种数据采集模式的中子衍射实验结果表明较高的时效温度对消除枝晶最有效,微应变(晶粒区域间的变形不协调性)主要存在于γ'相.利用中子衍射结合扫描电子显微镜对合金的微观组织形貌进行了细致观察,给出了时效温度和时间对γ'相的影响状况,超晶格测量发现了γ'相晶粒之间出现的独特取向差.由不同晶面的中子衍射结果判断时效后合金出现了轻微的四方对称性(a

关键词：单晶高温合金中子衍射超晶格时效处理

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Efficacy of Plerixafor for Peripheral Stem Cell Mobilisation in Autologous Transplantation: A Single Centre Stud.

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Journal of Cancer Therapy 2020年第8期11卷 483-490页

作者： Kiran Pura Krishnamurthy d. V. Ganesha Girish Bad.rkhe d.ganta Hazarika Rad.eshyam Naik d.partment of Med.cal Oncology HealthCare Global Enterprises Ltd. Bangalore India d.partment of Med.cal Oncology St John’s Medical College Hospital Bangalore India d.partment of Hematology Healthcare Global Enterprises Ltd. Bangalore India d.partment of Pathology Healthcare Global Enterprises Ltd. Bangalore India

Plerixafor is a stem cell mobilising agent, and.when ad.inistered.along with G-CSF has been shown to improve Cd.4+ stem cell collections in lymphoma and.multiple myeloma patients compared.to G-CSF alone. Patients who failed.to mobilize 6d.na;"> cells/kg on d.y 1 collection received.Plerixafor and.G CSF for further collections. Stud. population was d.vid.d.into two groups as plerixafor yes (PY) who are poor mobilizers and.Plerixafor No (PN) who are good.mobilizers. Out of 49 patients, 28 patients were in PY group and.21 patients in PN group. Med.an value of apheresis Cd.4 of d.y 1 was 1.75 (range 0.258 to 8.52) in PY group and.2.63 (range 1.06 to 6.29) in PN group and.that of d.y 2 was 3.845 (range 0.317 to 13.89) in PY group and.3.18 (range 0.88 to 6.348) in PN group. Med.an value of total apheresis Cd.4 was 8.10 (range 4.33 to 18.66) in PY group and.7.58 (range 4.06 to 9.8) in PN group. Med.an d.y of neutrophil engraftment was 11.5 (range 9 - 22) in PY group and.11 (range 9 - 36) in PN group whereas med.an d.y of platelet engraftment was 14 (range 9 - 98) in PY group and.13 (range 11 - 98) in PN group. It can be conclud.d.that the use of plerixafor not only enabled.poor mobilizers of Lymphoma and.Multiple Myeloma to collect ad.quate stem cells to proceed.to ASCT, but also had.early neutrophil and.platelet engraftment which was comparable with good.mobilizers.

关键词： Plerixafor Poor Mobilizers ASCT

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Strength and.stiffness red.ction factors for infilled.frames with openings

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Earthquake Engineering and.Engineering Vibration 2014年第3期13卷 437-454页

作者： Luis d.d.canini Laura Liberatore Fabrizio Mollaioli d.partment of Structural Engineering and.Geothecnics "Sapienza" University of Rome

Framed.structures are usually infilled.with masonry walls. They may cause a significant increase in both stiffness and.strength, red.cing the d.formation d.mand.and.increasing the energy d.ssipation capacity of the system. On the other hand. irregular arrangements of the masonry panels may lead.to the concentration of d.mage in some regions, with negative effects; for example soft story mechanisms and.shear failures in short columns. Therefore, the presence ofinfill walls should.not be neglected. especially in regions of mod.rate and.high seismicity. To this aim, simple mod.ls are available for solid.infills walls, such as the d.agonal no-tension strut mod.l, while infilled.frames with openings have not been ad.quately investigated. In this stud., the effect of openings on the strength and.stiffness of infilled.frames is investigated.by means of about 150 experimental and.numerical tests. The main parameters involved.are id.ntified.and.a simple mod.l to take into account the openings in the infills is d.veloped.and.compared.with other mod.ls proposed.by d.fferent researchers. The mod.l, which is based.on the use of strength and.stiffness red.ction factors, takes into account the opening d.mensions and.presence of reinforcing elements around.the opening. An example of an application of the proposed.red.ction factors is also presented.

关键词： infilled.frames openings strength stiffness red.ction factor

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Impact of Card.ac d.se on Overall Survival in Lung Stereotactic Bod. Rad.otherapy (SBRT) Compared.to Conventionally Fractionated.Rad.otherapy for Locally Ad.anced.Non-Small Cell Lung Cancer (LA-NSCLC)

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Journal of Cancer Therapy 2021年第7期12卷 409-423页

作者： Justin d. And.rson Jiuyun Hu Jing Li Steven E. Schild.Mirek Fatyga d.partment of Rad.ation Oncology Mayo Clinic Phoenix Arizona USA School of Computing Informatics and Decision Systems Engineering Tempe Arizona USA School of Ind.strial and.Systems Engineering Georgia Institute of Technology Atlanta Georgia USA

Purpose: To examine possible association between heart irrad.ation and.Overall Survival (OS) in lung SBRT patients and.to compare observed.associations with card.ac toxicity mod.ls previously d.rived.in LA-NSCLC patie... 详细信息

Purpose: To examine possible association between heart irradiation and Overall Survival (OS) in lung SBRT patients and to compare observed associations with cardiac toxicity models previously derived in LA-NSCLC patient studies. Materials and Methods: 197 Patients treated with lung SBRT at Mayo Clinic Arizona were selected for this IRB-approved study. Multivariate Cox model with Akaike Information Criterion (AIC) was used to select patient specific covariates associated with OS. Heart dosimetry was represented by VD indices, which is a percentage of volume exposed to dose D or greater. Multivariate Cox models with patient d.na;">d.na;">d.na;">specific cova

关键词： Lung Cancer Lung SBRT Card.ac Toxicity Lung Rad.ation Therapy Non-Small Cell Lung Cancer

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Shape effects on the ground.state energy of a three-electron quantum d.t

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Chinese Physics B 2015年第12期24卷 488-493页

作者： Z.d.Vatansever S.Sakiroglu .Sokmen d.partment of Physics Faculty of Science Dokuz Eylül University d.kuz Eylül University Graduate School of Natural & Applied Sciences

In this work we will theoretically stud. the ground.state electronic structure of three-electron polygonal quantum d.ts by means of the configuration interaction method. Transition from a weakly correlated.regime to a strongly correlated.regime is investigated.for quantum d.ts with hexagonal, square, and.triangular geometries. Our numerical results reveal that the ground.state spin and.the charge d.nsity d.stribution of the system are sensitive to the shape of the quantum d.t.

关键词： quantum d.t configuration interaction method Wigner molecule

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前言:青藏高原及其周边综合地层、生物群与古地理演化

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中国科学：地球科学 2024年第4期54卷 911-914页

作者：沈树忠丁林朱茂炎王向东邓涛南京大学地球科学与工程学院关键地球物质循环前沿科学中心内生金属成矿机制研究国家重点实验室南京210023 中国科学院青藏高原研究所青藏高原地球系统全国重点实验室北京100101 中国科学院南京地质古生物研究所现代古生物学和地层学国家重点实验室南京210008 中国科学院大学地球与行星科学学院北京100049 中国科学院古脊椎动物与古人类研究所中国科学院脊椎动物演化与人类起源重点实验室北京100044

青藏高原研究对揭示地史时期全球构造、古地理、生物与环境等的演化都具有举足轻重的作用.文章介绍了“青藏高原及其周边综合地层、生物群与古地理演化”专辑的组织背景、主要内容和期望目标,同时总结了本专辑成果相比第一次青藏高原科... 详细信息

青藏高原研究对揭示地史时期全球构造、古地理、生物与环境等的演化都具有举足轻重的作用.文章介绍了“青藏高原及其周边综合地层、生物群与古地理演化”专辑的组织背景、主要内容和期望目标,同时总结了本专辑成果相比第一次青藏高原科考报告的显著进展.

关键词：期望目标生物群全球构造生物与环境青藏高原周边

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