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Numerical Solution of Model of Cancer Invasion with Tissue

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Applied Mathematics 2013年第7期4卷 1050-1058页

作者： Farhad Hatami mohammad bagher ghaemi Department of Mathematics Iran University of Science and Technology Tehran Iran

Chemotaxis-haptotaxis model of cancer invasion with tissue remodeling is one of the important PDE’s systems in medicine, mathematics and biomathematics. In this paper we find the solution of chemotaxis-haptotaxis model of cancer invasion using the new homotopy perturbation method (NHPM). Then by comparing some estimated numerical result with simulation laboratory result, it shows that NHPM is an efficient and exact way for solving cancer PDE’s system.

关键词： Chemotaxis Haptotaxis Model of Cancer Invasion New Homotopy Perturbation Method

Global Existence of Classical Solutions to a Cancer Invasion Model

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Applied Mathematics 2012年第4期3卷 382-388页

作者： Khadijeh Baghaei mohammad bagher ghaemi Mahmoud Hesaaraki Department of Mathematics Iran University of Science and Technology Tehran Iran Department of mathematics Sharif University of Technology Tehran Iran

This paper deals with a chemotaxis-haptotaxis model of cancer invasion of tissue. The model consists of three reaction- diffusion- taxis partial differential equations describing interactions between cancer cells, matrix degrading enzymes, and the host tissue. The equation for cell density includes two bounded nonlinear density-dependent chemotactic and haptotactic sensitivity functions. In the absence of logistic damping, we prove the global existence of a unique classical solution to this model by some delicate a priori estimate

关键词： Cancer Invasion Model Chemotaxis Haptotaxis Global Existence

A dicationic,podand-like,ionic liquid water system accelerated copper-catalyzed azide-alkyne click reaction

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Chinese Chemical Letters 2014年第12期25卷 1643-1647页

作者： mohammad Javaherian Foad Kazemi Masoumeh ghaemi Department of Chemistry College of ScienceShahid Chamran University Department of Chemistry University for Advanced Studies in Basic Sciences

In this work,an effective,task specific,dicationic,podand-like ionic liquid was synthesized and applied to improve the capability features of click ***,to broaden the scope and decreasing the serious limitations of preparation methods of organic azides,a simple green procedure for the preparation of alkyl azides,the fundamental starting materials in click reactions,from alcohols under solvent-free conditions and microwave irradiation has been reported,for the first time.

关键词： Dicationic ionic liquid Click chemistry 1 2 3-Triazoles Alkyl azides Alkynes Microwave irradiation

Tree-Temperature Monitoring for Frost Protection of Orchards in Semi-Arid Regions Using Sprinkler Irrigation

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Agricultural Sciences in China 2009年第1期8卷 98-107页

作者： Ali Asghar ghaemi mohammad Rafie Rafiee Ali Reza Sepaskhah Irrigation Department College of AgricultureShiraz University

Automated over-tree sprinkler irrigation systems were developed and tested in two orchards located in two separate locations in southern Iran （a 0.17 ha peach orchard and a 0.24 ha orange orchard） to protect peach blossoms and orange trees leaves and fruits from low temperature damage. The experiment used a system that monitored the trees and air temperatures using two thermistors. The water application rate by the irrigation system was determined by an energy balance as implemented by the software FROSTPRO, In the peach orchard, the system was tested during three frost events during the spring of 2003 and three other events during the spring of 2004. The system successfully kept peach flowers above the critical temperature, i.e., -4.0℃ in spring 2004 （control block -4.12℃, and sprinkled block ＋0.5℃） during all events. Similar results were obtained in the orange orchard during three frost events in the winter of 2004, during which the tree temperatures were at least 2.5℃ above the critical temperature. Results from field tests show that the system can effectively protect the peach blossoms from damage. Determination done after the frost events showed a 12% blossom kill in the sprinkled blocks while in the unsprinkled control block a 41.5% blossom kill. Calculations indicated that when using variable application rates, the amount of water used can be reduced by 54.3%. Spatial distribution of minimum temperatures during the three frosts was also studied in Jahrom, Iran. Results showed a significant temperature control in the experimental block, especially in the central part of the orchard, but the block margins （about 3.6% of the total area） were at the risk of low temperature due to the wind drift effects.

关键词： automated sprinkler irrigation FROSTPORO frost protection peach orchard orange orchard

Facies Analysis and Sequence Stratigraphy of Silurian Carbonate Ramps in the Turan(Kopeh-Dagh) and Central Iran Plates with Emphasis on Gondwana Tectonic Event

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Acta Geologica Sinica(English Edition) 2015年第4期89卷 1276-1295页

作者： Zohreh NOWROUZI Asadollah MAHBOUBI Reza MOUSSAVI-HARAMI mohammad Hossein MAHMUDY GHARAIE Farzin ghaemi Department of Geology Faculty of SciencesFerdowsi University of Mashhad

Two sections from the Silurian deposits in the Central Iran Micro and Turan Plates were measured and sampled. These deposits are mostly composed of submarine volcanic rocks, skeletal and non-skeletal limestone, shale and sandstone that were deposited in low to high energy conditions （from tidal flat to deep open marine）. According to gradual deepening trend, wide lateral distribution of facies as well as absence of resedimentation deposits, a depositional model of a homoclinal ramp was proposed for these deposits. Field observations and facies distribution indicate that, two depositional sequences were recognized in both sections. These sections show similarities in facies and depositional sequence during the Early Silurian in the area. Although there are some opinions and evidences that demonstrated Paleo-Tethys rifting phase started at the Late Ordovician-Early Silurian, similarities suggest that the Turan and Iran Plates were not completely detached tectonic block during this time, and that their depositional conditions were affected by global sea level changes and tectonic events.

关键词： facies sequence stratigraphy Silurian Central Iran Plate Turan Plate

Interaction effects of water salinity and hydroponic growth medium on eggplant yield,water-use efficiency,and evapotranspiration

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International Soil and Water Conservation Research 2016年第2期4卷 99-107页

作者： Farnoosh Mahjoor Ali Asghar ghaemi mohammad Hossein Golabi Water Engineering Department College of AgricultureShiraz University*** ShirazIslamic Republic of Iran College of Natural and Applied Sciences University of GuamMangilaoGU 96923USA

Eggplant(Solanum melongena L.)is a plant native to tropical regions of Southeast *** water crisis and drought on the one hand and eggplant greenhouse crop development as one of the most popular fruit vegetables for people on the other hand,led to the need for more research on the use of saline water and water stress to optimize salinity level and their impact on eggplant evapotranspiration and encounter better yield and crop *** objective of the present study was to investigate the interactions of water salinity and hydroponic growth medium on qualitative and quantitative properties of eggplant and its water-use *** study used the factorial experiment based on completely randomized design with three replications of four levels of water salinity(electrical conductivity of 0.8(control),2.5,5,and 7 dS m^(-1))and three growth media(cocopeat,perlite,and a 50–50 mixture of the two by volume).Total yield,yield components,evapotranspiration,and water-use efficiency were determined during two growing periods,one each in 2012 and *** of these indices decreased significantly as water salinity *** with of 0.8 dS m^(-1) produced an average eggplant yield of 2510 g per plant in 2012 and 2600 g in *** highest yield was observed in *** with 7 dS m^(-1) reduced yield to 906 g per plant in 2012 and to 960 g in *** yield was observed in *** highest evapotranspiration values occurred in cocopeat at the lowest salinity in both *** and the cocopeat–perlite mixture were equally good *** mixture significantly improved the quantitative and qualitative properties of eggplant yield.

关键词： Cocopeat Greenhouse Penman–Montith Qualitative Water stress Salinity

Investigating the Effects of Madden-Julian Oscillation on Climate Elements of Iran (1980-2020)

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Journal of Atmospheric Science Research 2023年第2期6卷 21-32页

作者： Kourosh mohammadpour Zahra Hejazizadeh Hooshang ghaemi mohammad Salighe Department of Natural Geography Kharazmi UniversityTehran15447-33111Iran Tehran Institute of Meteorology and Atmospheric Sciences Tehran15447-33111Iran

The Madden-Julian Oscillation is one of the large-scale climate change patterns in the maritime tropics,with sub-seasonal time periods of 30 to 60 days affecting tropical and subtropical *** phenomenon can cause changes in various quantities of the atmosphere and ocean,such as pressure,sea surface temperature,and the rate of evaporation from the ocean surface in tropical *** this research,the effects of Madden-Julian fluctuation on the weather elements of Iran have been investigated with the aim of knowing the effects of different phases in order to improve the quality of forecasts and benefits in territorial *** first,the daily rainfall data of 1980-2020 were received from the National Meteorological Organization and quality *** the Wheeler and Hendon method,the two main components RMM1 and RMM2 were analyzed,based on which the amplitude of the above two components is considered as the main indicator of the intensity and weakness of this *** index is based on the experimental orthogonal functions of the meteorological fields,including the average wind levels of 850 and 200 hectopascals and outgoing long wave radiation(OLR)between the latitudes of 20 degrees south and 20 degrees *** clustering of the 7-day sequence with a component above 1 was used as the basis for clustering all eight phases,and by calculating the abnormality of each phase compared to its long term in the DJF time frame,the zoning of each phase was produced *** the end,phases 1,2,7,8 were concluded as effective phases in Iran’s rainfall and phases 3,4,5,6 as suppressive phases of Iran’s rainfall.

关键词： Madden-Julian oscillation Tropical convection precipitation Long-wave radiation Sub-seasonal oscillation

Interleukin-12 as a Genetic Adjuvant Enhances Hepatitis C Virus NS3 DNA Vaccine Immunogenicity

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Virologica Sinica 2013年第3期28卷 167-173页

作者： Malihe Naderi Atefeh Saeedi Abdolvahab Moradi Mishar Kleshadi mohammad Reza Zolfaghari Ali Gorji Amir ghaemi Department of Microbiology Qom branch Islamic Azad University Department of Microbiology Lahijan Branch Islamic Azad University Golestan Research Center of Gastroenterology and Hepatology-GRCGH Department of Microbiology Golestan University of Medical Sciences Shefa Neuroscience Research Centre Institut für Physiologie I Westflische Wilhelms-Universitt Münster Klinik und Poliklinik für Neurochirurgie Westf lische Wilhelms-Universitt Münster

Hepatitis C virus (HCV) chronic infection is a worldwide health problem, and numerous efforts have been invested to develop novel vaccines. An efficient vaccine requires broad immune response induction against viral proteins. To achieve this goal, we constructed a DNA vaccine expressing nonstructural 3 (NS3) gene (pcDNA3.1-HCV-NS3) and assessed the immune response in C57BL/6 mice. In this study, the NS3 gene was amplified with a nested-reverse transcriptase-polymerase chain reaction (RT-PCR) method using sera of HCV-infected patients with genotype 1a. The resulting NS3 gene was subcloned into a pcDNA3.1 eukaryotic expression vector, and gene expression was detected by western blot. The resultant DNA vaccine was co-administered with interleukin-12 (IL-12) as an adjuvant to female C57BL/6 mice. After the final immunizations, lymphocyte proliferation, cytotoxicity, and cytokine levels were assessed to measure immune responses. Our data suggest that co-administration of HCV NS3 DNA vaccine with IL-12 induces production of significant levels of both IL-4 and interferon (IFN)-γ (p<0.05). Cytotoxicity and lymphocyte proliferation responses of vaccinated mice were significantly increased compared to control (p<0.05). Collectively, our results demonstrated that co-administration of HCV NS3 and IL-12 displayed strong immunogenicity in a murine model.

关键词： Hepatitis C virus (HCV) NS3 Interleukin-12 DNA vaccine