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Simple glycolipids of microbes:Chemistry,biological activity and metabolic engineering

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Synthetic and Systems Biotechnology 2018年第1期3卷 3-19页

作者： ahmad mohammad Abdel-Mawgoud Gregory Stephanopoulos Department of Chemical Engineering Massachusetts Institute of Technology77 Massachusetts Ave.CambridgeMA 02139USA

Glycosylated lipids(GLs)are added-value lipid derivatives of great *** their interesting surface activities that qualify many of them to act as excellent ecological detergents,they have diverse biological activities with promising biomedical and cosmeceutical ***,especially those of microbial origin,have interesting antimicrobial,anticancer,antiparasitic as well as immunomodulatory ***,GLs are hardly accessing the market because of their high cost of *** believe that experience of metabolic engineering(ME)of microbial lipids for biofuel production can now be harnessed towards a successful synthesis of microbial GLs for biomedical and other *** review presents chemical groups of bacterial and fungal GLs,their biological activities,their general biosynthetic pathways and an insight on ME strategies for their production.

关键词： Biosurfactant Glycolipids biosynthesis Glycosyl/acyl transferases Glycosides Physiological roles Lipid biotechnology

Multiplex qPCR for serodetection and serotyping of hepatitis viruses: A brief review

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World Journal of Gastroenterology 2016年第20期22卷 4824-4834页

作者： mohammad Irshad Priyanka Gupta Dhananjay Singh Mankotia mohammad ahmad Ansari Clinical biochemistry division Department of Laboratory Medicine All India Institute of Medical Sciences New Delhi 110029 India

The present review describes the current status of multiplex quantitative real time polymerase chain reaction(q PCR) assays developed and used globally for detection and subtyping of hepatitis viruses in body fluids. Several studies have reported the use of multiplex q PCR for the detection of hepatitis viruses, including hepatitis A virus(HAV), hepatitis B virus(HBV), hepatitis C virus(HCV), hepatitis D virus(HDV), and hepatitis E virus(HEV). In addition, multiplex q PCR has also been developed for genotyping HBV, HCV, and HEV subtypes. Although a single step multiplex q PCR assay for all six hepatitis viruses, i.e., A to G viruses, is not yet reported, it may be available in the near future as the technologies continue to advance. All studies use a conserved region of the viral genome as the basis of amplification and hydrolysis probes as the preferred chemistries for improved detection. Based on a standard plot prepared using varying concentrations of template and the observed threshold cycle value, it is possible to determine the linear dynamic range and to calculate an exact copy number of virus in the specimen. Advantages of multiplex q PCR assay over singleplex or other molecular techniques in samples from patients with co-infection include fast results, low cost, and a single step investigation process.

关键词： Co-infection Viral genome Quantitative real-time polymerase chain reaction Genotyping techniques Serotyping Hepatitis viruses

Robust design of sliding mode control for airship trajectory tracking with uncertainty and disturbance estimation

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Journal of Systems Engineering and Electronics 2024年第1期35卷 242-258页

作者： WASIM Muhammad ALI Ahsan CHOUDHRY mohammad ahmad SHAIKH Inam Ul Hasan SALEEM Faisal Department of Aeronautics and Astronautics Engineering Institute of Space TechnologyIslamabad 44000Pakistan Department of Electrical Engineering University of Engineering and TechnologyTaxila 47080Pakistan Department of Measurements and Control Systems Silesian University of TechnologyGliwice 44-101Poland The Joint Doctoral School Silesian University of TechnologyGliwice 44-100Poland

The robotic airship can provide a promising aerostatic platform for many potential *** applications require a precise autonomous trajectory tracking control for *** has a nonlinear and uncertain *** is prone to wind disturbances that offer a challenge for a trajectory tracking control *** paper addresses the airship trajectory tracking problem having time varying reference path.A lumped parameter estimation approach under model uncertainties and wind disturbances is opted against distributed *** uses extended Kalman filter(EKF)for uncertainty and disturbance *** estimated parameters are used by sliding mode controller(SMC)for ultimate control of airship trajectory *** comprehensive algorithm,EKF based SMC(ESMC),is used as a robust solution to track airship *** proposed estimator provides the estimates of wind disturbances as well as model uncertainty due to the mass matrix variations and aerodynamic model *** stability and convergence of the proposed method are investigated using the Lyapunov stability *** simulation results show that the proposed method efficiently tracks the desired *** method solves the stability,convergence,and chattering problem of SMC under model uncertainties and wind disturbances.

关键词： airship chattering extended Kalman filter(EKF) model uncertainties estimation sliding mode controller(SMC)

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Isolation,identification,characterization and antibiotic sensitivity profile of pathogenic Legionella pneumophila isolates from different water sources

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Asian Pacific Journal of Tropical Biomedicine 2017年第5期7卷 411-415页

作者： Kannan Subbaram Hemalatha Kannan Majed mohammad ahmad Masadeh Department of Medical Preparatory Year–Biology Al-Ghad International Colleges for Applied Medical Sciences(Male)RiyadhSaudi Arabia Department of Medical Laboratory Sciences&Pathology Jimma UniversityJimmaEthiopia Department of Pharmaceutical Technology Jordan University of Science and TechnologyIrbid 22110Jordan

Objective:To investigate the prevalence,isolation,identification,characterization,antibiotic profile and pathogenicity of Legionellae isolated from various set of ***:A total of 400 water samples were collected from different water *** samples were pretreated using acid treatment followed by concentration and culture on buffered charcoal yeast extract *** like ability of Legionella isolates to grow in various p H range,effect of different concentrations of chlorine and effect of different temperature optima were set *** tests were performed to separate Legionellae into *** sensitivity tests and test for pathogenicity were also conducted on isolated ***:The rates of isolation of Legionella pneumophila(***) in different water sources were found to be 20%(lakes),10%(ponds),8%(water-tanks) and 1%(rivers).Most of the isolates could grow in variable p H 6–8 and it could also survive the normal level of chlorination and even at temperature of 42 *** species of Legionellae resulted in identification of 5 different species,*** being the dominant *** of *** were resistant to many *** of Legionellae into intracerebral route of suckling mice revealed that *** was the most ***:Serious and fatal *** infections may be transmitted through *** can survive under various conditions in various water *** is the important pathogen causing human *** challenge prevails to health care professionals because these Legionellae acquired antibiotic resistance to many routinely prescribed antibiotics.

关键词： Legionella pneumophila Legionellae Animal pathogenicity Virulence Water sources Antibiotic resistance

Influence of diversion angle on water and sediment flow into diversion channel

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International Journal of Sediment Research 2020年第6期35卷 600-608页

作者： Nashwan Kamalaldeen Alomari Badronnisa Yusuf Thamer ahmad mohammad Abdul Halim Ghazali Department of Dams and Water Resources College of EngineeringUniversity of Mosul Department of Civil Engineering Faculty of EngineeringUniversiti Putra MalaysiaUPM Serdang Department of Water Resources Engineering University of Baghdad

Accumulation of the sediment in the stream of the diversion channels adversely affects its operational *** channels are often constructed perpendicular to the main *** this study,the water flow and sediment transport in the diversion channel with different angles were investigated in an attempt to maximize water discharge and minimize sediment discharge.A physical model with movable bed was used to simulate water and sediment flow with five diversion angles(θ) between(30°-90°).Moreover,three bed width ratios(Br)(the relation between diversion to main channel bed width) between 30% and 50% and five total discharges between(7.25 L/s to 12.25 L/s) were considered for each case of(θ).The results showed,up to 10%,increasing in proportion discharge ratios for 30 and 45 diversion angles compared with 90° diversion *** results also showed that the lowest diversion sediment concentration was provided by the(0) of *** all scenarios,the average proportion concentration reduction was 64%,compared with 90°diversion *** observation of the diversion system mechanism confirmed that decreased(θ) result in decreased sediment concentrations in the diversion *** conclusion,the diversion channel water and sediment discharge could be effectively managed by changing the(θ) to 30° or 45° instead of 90°.

关键词： Diversion channel Diversion angle Lowest diversion sediment concentration Bed width ratio Sediment concentration

CT Brain Image:Abnormalities Recognition and Segmentation

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Journal of Donghua University(English Edition) 2010年第2期27卷 246-249页

作者： TONG Hau-Lee mohammad Faizal ahmad Fauzi Ryoichi Komiya HAW Su-Cheng Faculty of Information Technology Multimedia UniversityJalan Multimedia Faculty of Engineering Multimedia UniversityJalan Multimedia

In order to develop an automated segmentation system for Computed Tomography （CT） brain images, a new approach which consists of several unsupervised segmcotation techniques was introduced. The system segments the CT brain images into three partitions, i. e., abnormalities, cerebrospinal fluid （CSF）, and brain matter. Our approach consists of two phase-segmentation methods. In the first phase segmentation, k-means and fuzzy cmeans （FCM） methods were implemented to segment and transform the images into the binary images. Based on the connected component in binary images, a decision tree was employed for the annotation of normal or abnormal regions. In the second phase segmentation, the modified FCM with population-diameter independent （PDI） segmentation was applied to segment the images into CSF and brain matter. The experimental results have shown that our proposed system is feasible and yield satisfactory results.

关键词： computed tomography ursupervised segmentation k-means fuzzy c-means population-diameter indepentdent

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A Novel Krill Herd Based Random Forest Algorithm for Monitoring Patient Health

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Computers, Materials & Continua 2023年第5期75卷 4553-4571页

作者： Md.Moddassir Alam Md Mottahir Alam Muhammad Moinuddin mohammad Tauheed ahmad Jabir Hakami Anis ahmad Chaudhary Asif Irshad Khan Tauheed Khan Mohd Department of Health Information Management and Technology University of Hafr Al-BatinSaudi Arabia Department of Electrical and Computer Engineering Faculty of EngineeringKing AbdulazizJeddah21589Saudi Arabia Center of Excellence in Intelligent Engineering Systems King Abdul Aziz UniversityJeddahSaudi Arabia College of Medicine King Khalid UniversityAbhaSaudi Arabia Department of Physics College of ScienceJazan UniversityP.O.Box.114Jazan45142Saudi Arabia Department of Biology College of ScienceImam Mohammad Ibn Saud Islamic University(IMSIU)Riyadh11623Saudi Arabia Computer Science Department Faculty of Computing and Information TechnologyKing Abdulaziz UniversityJeddah21589Saudi Arabia Department of Math and Computer Science Augustana CollegeIL61201United States

Artificial Intelligence(AI)is finding increasing application in healthcare *** learning systems are utilized for monitoring patient health through the use of IoT sensor,which keep track of the physiological state by way of various health ***,early detection of any disease or derangement can aid doctors in saving patients’***,there are some challenges associated with predicting health status using the common algorithms,such as time requirements,chances of errors,and improper *** propose an Artificial Krill Herd based on the Random Forest(AKHRF)technique for monitoring patients’health and eliciting an optimal prescription based on their health *** begin with,various patient datasets were collected and trained into the system using IoT *** a result,the framework developed includes four processes:preprocessing,feature extraction,classification,and result ***,preprocessing removes errors,noise,and missing values from the dataset,whereas feature extraction extracts the relevant ***,in the classification layer,we updated the fitness function of the krill herd to classify the patient’s health status and also generate a *** found that the results fromthe proposed framework are comparable to the results from other state-of-the-art techniques in terms of sensitivity,specificity,Area under the Curve(AUC),accuracy,precision,recall,and F-measure.

关键词： Healthcare system health monitoring clinical decision support internet of things artificial intelligence machine learning diagnosis

Traffic Priority-Aware Medical Data Dissemination Scheme for IoT Based WBASN Healthcare Applications

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Computers, Materials & Continua 2022年第6期71卷 4443-4456页

作者： Muhammad Anwar Farhan Masud Rizwan Aslam Butt Sevia Mahdaliza Idrus mohammad Nazir ahmad Mohd Yazid Bajuri Department of Computer Science NFC Institute of Engineering and Fertilizer ResearchFaisalabadPakistan Department of Statistics and Computer Science Faculty of Life Sciences Business ManagementUniversity of Veterinary and Animal SciencesLahorePakistan Department of Electronics Engineering NED University of Engineering and TechnologyKarachiPakistan School of Electrical Engineering Universiti Teknologi MalaysiaJohor BahruMalaysia Institute of IR4.0 Universiti Kebangsaan MalaysiaBangiSelangorMalaysia Department of Orthopedics and Traumatology Faculty of MedicineUniversiti Kebangsaan MalaysiaKuala LumpurMalaysia

Wireless Body Area Sensor Network(WBASN)is an automated system for remote health monitoring of *** under umbrella of Internet of Things(IoT)is comprised of small Biomedical Sensor Nodes(BSNs)that can communicate with each other without human *** BSNs can be placed on human body or inside the skin of the patients to regularly monitor their vital *** BSNs generate critical data as it is related to patient’s *** data traffic can be classified as Sensitive Data(SD)and Non-sensitive Data(ND)packets based on the value of vital *** data packets have different priority to *** ND packets may tolerate some delay or packet loss whereas,the SD packets required to be delivered on time with minimized packet loss otherwise it can be life threating to the *** this research,we propose a Traffic Priority-aware Medical Data Dissemination(TPMD2)scheme forWBASN to deliver the data packets according to their priority based on the sensitivity of the *** assessment of the proposed scheme is carried out in various *** simulation results of the TPMD2 scheme indicate a significant improvement in packets delivery,transmission delay and energy efficiency in comparison with the existing schemes.

关键词： WBANS wearable technology priority routing eHealth applications remote health monitoring

Improving power system dynamic performance using attuned design of dual-input PSS and UPFC PSD controller

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Frontiers of Electrical and Electronic Engineering in China 2012年第4期7卷 416-426页

作者： Yashar HASHEMI Rasool KAZEMZADEH mohammad Reza AZIZIAN ahmad SADEGHI YAZDANKHAH Faculty of Electrical Engineering Sahand University of TechnologyTabriz Iran

The objective of this work is the coordinated design of controllers that can enhance damping of power system swings. With presence of flexible AC transmission system （FACTS） device as unified power flow controller （UPFC）, three specific classes of the power system stabilizers （PSSs） have been investigated. The first one is a conventional power system stabilizer （CPSS）; the second one is a dual-input power system stabilizer （dual-input PSS）; and the third one is an accelerating power PSS model （PSS2B）. Dual-input PSS and PSS2B are introduced to maintain the robustness of control performance in a wide range of swing frequency. Uncoordinated PSS and UPFC damping controller may cause unwanted interactions; therefore, the simultaneous coordinated tuning of the controller parameters is needed. The problem of coordi- nated design is formulated as an optimization problem, and particle swarm optimization （PSO） algorithm is employed to search for optimal parameters of controllers. Finally, in a system having a UPFC, comparative analysis of the results obtained from application of the dual-input PSS, PSS2B, and CPSS is presented. The eigenvalue analysis and the time-domain simulation results show that the dual-input PSS ＆ UPFC and the PSS2B ＆ UPFC coordination provide a better performance than the conventional single-input PSS ＆ UPFC coordination. Also, the PSS2B ＆ UPFC coordination has the best performance.

关键词： simultaneous coordinated design unifiedpower flow controller (UPFC) power swing damping(PSD) dual-input power system stabilizer