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Depression among medical students in Tunisia:Prevalence and associated factors

World Journal of Psychiatry 2023年第10期13卷 772-783页

作者： Badii Amamou Sondess Alouani Amjed Ben Haouala Saoussen Alouani mohamed Ayoub tlili Ahmed Mhalla Ferid Zaafrane Lotfi Gaha Department of Psychiatry Fattouma Bourguiba University Hospital of MonastirMonastir 5000Tunisia Department of Family and Community Medicine Faculty of Medicine of SousseSousse 4002Tunisia

BACKGROUND Medical school is known for its lengthy process,which is both physically and emotionally ***’mental balance would shrink as they progress in their medical training.A systematic review and meta-analysis reported that the prevalence of depressive symptoms among medical students remained relatively constant at 27.2%.AIM To assess the prevalence of depressive symptoms among Tunisian medical students and evaluate its associated *** This is a descriptive cross-sectional study that was carried out in the second semester of the academic year 2017/2018,between April 2018 and July 2018 among 1138 medical *** were collected using a socio-demographic questionnaire and the Beck Depression Inventory-II(BDI-II).RESULTS Sixty-four percent(n=728)of the participants had depressive symptoms,of which 266(23.4%)met the criteria for mild,271(23.8%)for moderate,and 191(16.8%)for severe depressive *** gender,low socio-economic level,smoking habits and history of mental disorder,performing leisure and physical activities,satisfaction toward a career choice,and happiness perception were the main prognostic factors for depression among medical *** academic grades may not be considered a prognostic factor,final-year students appeared to be less depressive than their *** These findings give insight into mental health issues and comorbidities among Tunisian medical *** is a hopeful request for decision-makers and academic authorities to set serious measures and draw effective interventions to minimize the currency of psychological distress among this subpopulation.

关键词： Depression Psychiatry Medical students Mental health Beck Depression Inventory Tunisia

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Donnan Dialysis Removal of Nitrate from Water: Effects of Process Parameters

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American Journal of Analytical Chemistry 2015年第6期6卷 569-576页

作者： Thouraya Turki Raghda Hamdi mohamed tlili mohamed Ben Amor Laboratory of Natural Water Treatment Centre of Water Researches and Technologies Borj Cedria Science and Technology Park Soliman Tunisia

Excess or lack of levels of nitrate in drinking water is harmful to the human health, the concentration of NO-3 ions must be maintained at 50 mg/l. Donnan dialysis (DD) used as a driving force of the concentration gradient is an effective and simple technique for nitrate removal. In this paper, the transport of nitrate through an AMX anion-exchange membrane has been studied as a function of driving ion nature, receiver phase concentration, flow rate, temperature and agitation rate under Donnan dialysis condition. It was observed that the hydrodynamic conditions and temperature were the main variables affecting the transmembrane flow. As the driving ion, the chloride ion is more efficient than the hydrogeneocarbonate ion. The systematic study of the different parameters involved showed that the nitrate removal efficiency obtained with a feed synthetic nitrate solution (62 ppm) was off 96%. This efficiency slightly decreases for a tap water containing the same nitrate concentration;it was about 84%. This can be attributed to the complex ionic composition of the natural water.

关键词： Nitrate Natural Water Donnan Dialysis Anion Exchange Membrane

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Monitoring the variation of soil quality with sewage sludge application rates in absence of rhizosphere effect

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International Soil and Water Conservation Research 2020年第3期8卷 245-252页

作者： Rahma Inès Zoghlami Helmi Hamdi Sonia Mokni-tlili Sarra Hechmi mohamed Naceur Khelil Nadhira Ben Aissa mohamed Moussa Habib Bousnina Saoussen Benzarti Naceur Jedidi Arid Regions Institute University of GabèsMèdenine4119Tunisia Water Research and Technology Center University of CarthageP.O.Box 273Soliman8020Tunisia Center for Sustainable Development College of Arts and SciencesQatar UniversityP.O.Box 2713DohaQatar National Institute for Research in Rural Engineering Water and ForestryP.O.Box 10Ariana2080Tunisia National Institute of Agronomy 43 Av.Charles NicolleTunis1082Tunisia College of Agriculture at Mograne University of Carthage1121MograneTunisia

Agricultural soils in semi-arid regions have frequently been degraded due to adverse climatic conditions,organic matter depletion,and poor farming *** enhance soil quality,this study examines the reuse of sewage sludge(SS)as an available source of organic matter in a typical Mediterranean sandy-loam ***,we studied the cumulative effect of two annual applications of 40,80 and 120 tons of sludge per ha on soil quality in absence of *** dose-dependent improvement of organic matter content was the most significant event that reflected sludge application rates,and consequently influenced other soil ***,soil structural stability increased by 13.3%,28.8%and 59.4%for treatments SS-40,SS-80 and SS-120 respectively as compared to unamended *** stability improvement was also confirmed by the dose-dependent variation of other edaphic factors including calcium content,the microbial quotient as well as Welt and C:N *** param-eters are involved in cementing soil aggregates by cation bridging,the formation of microbial mucilage,and clay-humic *** magnetic susceptibility(SMS)was measured in situ as a possible rapid tool to evaluate soil *** showed significant correlation with sludge dose and stability amelioration testifying to the aggregation role that can play Al2O3 and particularly Fe2O3 minerals added by the hematite-rich ***,analytical results and field observations revealed no trends of soil salinization or acidification by excessive sludge *** avoiding the rhizosphere effect,outcomes could reflect the resilience and intrinsic capacity of the soil to cope with excessive sludge loads.

关键词： Sandy loam soil Urban sewage sludge Structural stability Soil degradation Aggregation Magnetic susceptibility

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Functionalized CVD monolayer graphene for label-free impedimetric biosensing

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Nano Research 2015年第5期8卷 1698-1709页

作者： Shimaa Eissa Gaston Contreras Jimenez Farzaneh Mahvash Abdeladim Guermoune Chaker tlili Thomas Szkopek Mohammed Zourob mohamed Siaj Institut national de la recherche scientifique Centre - Energie Matefiaux et Telecommunications 1650 BouL Lionel Boulet Varennes (Quebec) J3X 1S2 Canada Departemen t de Chimie et Biochimie Universite du Quebec a Montreal Mon trial Quebec H3C 3P8 Canada Dept. ofElectricaland Computer Engineering McGill University Montreal Quebec H3A 2A7 Canada Cranfield Health Vincent Building Cranfield University Cranfield Bedfordshire UK

Recent advances in large area graphene growth have led to many applications in different areas. In the present study, chemical vapor deposited （CVD） monolayer graphene supported on glass substrate electrochemical biosensing applications was examined as electrode material for We report a facile strategy for covalent functionalization of CVD monolayer graphene by electrochemical reduction of carboxyphenyl diazonium salt prepared in situ in acidic aqueous solution. The carboxyphenyl-modified graphene is characterized using Raman spectroscopy, X-ray photoelectron spectroscopy （XPS）, and atomic force microscopy （AFM）, as well as electrochemical impedance spectroscopy （hIS）. We also show that the number of grafted carboxyphenyl groups on the graphene surface can be controlled by the number of cyclic voltammetry （CV） scans used for electrografting. We further present the fabrication and characterization of an immunosensor based on immobilization of ovalbumin antibody on the graphene surface after the activation of the grafted carboxylic groups via EDC/NHS chemistry. The binding between the surface-immobilized antibodies and ovalbumin was then monitored using Faradaic EIS in [Fe（CN）6]^3-/4- solution. The percentage change of charge transfer resistance （Rct） after binding exhibited a linear dependence for ovalbumin concentrations ranging from 1.0 pg·mL^-1 to 100 ng·mL^-1, with a detection limit of 0.9 pg·mL^-1. Our results indicate good sensitivity of the developed functionalized CVD graphene platform, paving the way for using CVD monolayer graphene in a variety of electrochemical biosensing devices.

关键词： CVD graphene electrochemical impedance spectroscopy Biosensor diazoniumfunctionalization

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CRP Binding Kinetics Enhancement Using Local Narrowing into a Bent Channel: Finite Element Analysis

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Engineering（科研） 2022年第1期14卷 62-75页

作者： mohamed Bahri Imen Dermoul Marshet Getaye mohamed Amin Elaguech Khouloud Djebbi Mounir Ben Ali Chaker tlili Deqiang Wang Chongqing School University of Chinese Academy of Sciences Chongqing China Chongqing Institute of Green and Intelligent Technology Chinese Academy of Sciences Chongqing China University of Chinese Academy of Sciences Beijing China Preparatory Institute for Engineering of Nabeul IPEIN University of Carthage Campus Universitaire Merazka Tunisia NANOMISENE Lab LR16CRMN01 Centre for Research on Microelectronics and Nanotechnology of Sousse Technopole of Sousse Sousse Tunisia University of Sousse Higher Institute of Applied Sciences and Technology of Sousse GREENS-ISSAT Cité Ettafala Sousse Tunisia

Binding kinetics enhancement of a microfluidic biosensor into a micro-channel through the application of a supplementary mechanism has received tremendous attention because of the obtained significant enhancement factor. However, biosensor’s performance enhancement using only simple channel engineering is still rarely realized. Herein, we present a novel design of a complex reactive protein (CRP) biosensor into a U-shaped channel with a sensitive membrane located in the middle of the bent zone. Various critical factors affecting the equilibrium binding time are numerically investigated. The turn geometry is then optimized when the arc length along the inner and outer radii is almost the same, which leads to locally minimizing the channel height overhead the reaction surface and improves the analyte transport towards the sensing area. The numerical studies reveal that applying a local narrowing above the reaction surface can notably enhance the trapping and the surface formation of complex antibody-antigen, thus upgrading the biosensor performance. This work puts a significant advance towards microfluidic channel engineering and the exploration of micro-flow injection experimental studies.

关键词： Finite Elements Method Binding Reaction CRP Biosensor Microfluidic System Microchannel Turn Numerical Simulation

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