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Acute Toxicity and Anthelmintic Effects of Gomphrena serrata L. (Amaranthaceae) Extracts on Adult Worms and Eggs of Haemonchus contortus

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Pharmacology & Pharmacy 2024年第5期15卷 207-221页

作者： Hippolyte Ouedraogo mohamed Bonewendé Belemlilga Aristide Traore Gilchrist Abdoul Laurent Boly Félicité moyenga Gueswindé Geoffroy Ouedraogo Sylvain Ilboudo Lazare Belemnaba Sylvin Ouedraogo Laboratoire de Recherche-Dé veloppement de Phytom&#233dicaments et M&#233dicaments (LR-D/PM) Institut de Recherche en Sciences de la Sant&#233 (IRSS) Centre National de la Recherche Scientifique et Technologique (CNRST) Ouagadougou Burkina Faso Laboratoire de Dé veloppement du M&#233dicament (LADME) Centre de Formation deRecherche et d&#8217Expertises en Sciences du M&#233dicament (CEA-CFOREM) &#201cole Doctorale Sciences de la Sant&#233 (ED2S) Universit&#233 Joseph KI-ZERBO Ouagadougou Burkina Faso International Research Laboratory-Environnement Sant&#233 Soci&#233t&#233s (IRL 3189 ESS) CNRS/CNRST/UCAD/UGB/USTTB Ouagadougou Burkina Faso

Gomphrena serrata L. (Amaranthaceae) is a medicinal plant widely used traditionally in rural areas to treat many diseases, including gastrointestinal helminthiasis of small ruminants. This work aims to estimate the plant extracts phytochemical potential and study the activities of the aqueous decoction (GS_AD), aqueous macerate (GS_Am), and hydroalcoholic macerate (GS_HEm) of Gomphrena serrata extracts on two developmental stages (eggs and adult worms) of Haemonchus contortus. Phytochemical screening was carried out. The acute toxicity test was performed according to the Organisation for Economic Co-operation and Development (OECD) test guideline 423. The Haemonchus contortus eggs hatching inhibition test was performed left to incubate for 48 hours in the presence of the different plant extracts at increasing concentrations of 0.125;0.25;0.5;0.625;1;2;3 mg/mL. For the motility inhibition test on adult worms, the worms were contacted with the extracts at concentrations of 0.75;1;1.25;1.5;2;3;4 mg/mL and left to incubate for 24 hours. Albendazole and levamisole were used as standard. Phytochemical screening revealed the presence of tannins, saponins, reducing compounds, coumarins and derivatives, anthocyanins, steroids, triterpenes, and flavonoids. An acute toxicity study showed that the oral LD50 value of G. serrata was estimated to be 5000 mg/kg. All extracts showed an effect on both stages of parasite development. The hatching inhibition rate was 100% from 3 mg/mL for all three extracts. The rate of inhibition of motility was 100% from 4 mg/mL for each extract. HEm is more efficient on eggs and Haemonchus contortus adult worms than other extracts with IC50 of 0.457 mg/mL and LC50 of 1.329 mg/mL, respectively. These results suggest that Gomphrena serrata, a plant used by farmers, has anthelmintic properties.

关键词： Gomphrena serrata Haemonchus contortus Anthelmintic In Vitro

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Cement and Lime Stabilization Effect on the Evolutivity of an Expansive Overconsolidated Clay

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Journal of Civil Engineering and Architecture 2024年第3期18卷 134-140页

作者： mohamed Khemissa Geomaterials Development Laboratory Mohamed Boudiaf UniversityM'sila 28000Algeria

This paper presents and analyzes the results of a series of compaction,fragmentability and damage tests performed on an expansive overconsolidated clay treated with cement and *** clay was obtained from the urban site of Sidi-Hadjrès city(wilaya of m'sila,Algeria),where significant damages frequently appears in the road infrastructures,roadway systems and light *** results obtained show that the geotechnical parameters values deduced from these tests are concordant and confirm the evolutivity of this natural clay treated with composed Portland cement or extinct lime and compacted under optimum Proctor conditions.

关键词： Expansive clay evolutivity treatment cement lime fragmentability coefficient damage coefficient

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Cervical meningocele about 2 Operated Cases

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Open Journal of modern Neurosurgery 2024年第1期14卷 1-7页

作者： mohamed El Hassimi Cissé mamadou Salia Diarra N’Famara Sylla Abdoulaye Diop Izoudine Blaise Koumaré Théodore Habib maxime Coulibaly Oumar Diallo Drissa Kanikomo Neurosurgery Department of CHU mère-Enfant “Le Luxembourg” Bamako Mali Neurosurgery Unit of Army medico-Surgical Center of Bamako Bamako Mali Neurosurgery Department of CHNU de Fann Dakar Sénégal Neurosurgery Department of CHU Hospital du mali Bamako Mali Neurosurgery Department of CHU Gabriel Touré Bamako Mali

Cervical meningoceles are the least common forms of spina bifida, representing between 4% to 8% of all spinal dysraphisms. They are not accompanied by neurological deficit in childhood but attached cord syndrome can occur with growth. Surgical treatment, in addition to avoiding rupture and correcting the aesthetic damage, will preserve neurological functions. We report 2 cases that we took care of. They are a 5-month-old infant and a 3-year-old girl. The first presented a 7 cm rounded meningocele pedunculated through the C1 lamina defect. The second presented an 8.6 cm polylobed meningocele pedunculated through the C2 lamina defect. They both underwent surgery with good progress.

关键词： Cervical meningocele Spinal Dysraphism Spina Bifida

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Network Analysis for Projects with High Risk Levels in Uncertain Environments

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Computers, materials & Continua 2022年第1期70卷 1281-1296页

作者： mohamed Abdel-Basset Asmaa Atef mohamed Abouhawwash Yunyoung Nam Nabil m.AbdelAziz Faculty of Computers and Informatics Zagazig UniversityZagazig44519Egypt Department of mathematics Faculty of ScienceMansoura UniversityMansoura35516Egypt Department of Computational mathematics Scienceand Engineering(CMSE)Michigan State UniversityEast Lansing48824MIUSA Department of Computer Science and Engineering Soonchunhyang UniversityAsan31538Korea

The critical path method is one of the oldest and most important techniques used for planning and scheduling *** main objective of project management science is to determine the critical path through a network representation of *** critical path through a network can be determined by many algorithms and is useful for managing,monitoring,and controlling the time and cost of an entire *** essential problem in this case is that activity durations are uncertain;time presents considerable uncertainty because the time of an activity is not always easily or accurately *** issue increases the need to use neutrosophic theory to solve the critical path ***-world problems are characterized by a lack of precision,consistency,and *** concept of neutrosophic sets has been introduced as a generalization of fuzzy,intuitionistic fuzzy,and crisp sets to overcome the ambiguity surrounding real-world ***-,falsity-,and indeterminacy-membership functions are used to express neutrosophic *** study was performed to examine a neutrosophic event-oriented algorithm for determining the critical path in activity-on-arc *** activity time estimates are presented as trapezoidal neutrosophic numbers,and score and accuracy functions are used to obtain a crisp model of the *** appropriate numerical example is then used to explain the proposed method.

关键词： Project management project life cycle project planning project scheduling CPm neutrosophic set theory trapezoidal neutrosophic number

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Giant Cerebriform Nevus Cell Nevus of the Scalp: A Case Report

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Open Journal of modern Neurosurgery 2024年第1期14卷 8-13页

作者： mohamed El Hassimi Cissé N’daraw Ndoye Anne Aurore Sankale Pauline Diousse Abdoulaye Diop Alvine Nah Doe Sagar Diop momar Codé Ba Seydou Boubakar Badiane Neurosurgery Department of CHU mère-Enfant “Le Luxembourg” Bamako Mali Neurosurgery Department of CHNU de Fann Dakar Sénégal Plastic and Cosmetic Surgery Department of CHU Le Dantec Dakar Sénégal Dermatology Department of Thiès Regional Hospital Thiès Sénégal

Giant cerebriform nevus cell nevus of the scalp is an extremely rare form of congenital melanocytic nevus. Giant cerebriform nevus of the scalp has a major psychosocial impact because of its unsightly appearance with fetid maceration. We report the case of a 35-year-old woman who had a painless, malodorous swelling of the cerebriform scalp measuring 20 × 17 cm in diameter with a wide base of insertion at the occipital level adhering to the deep planes. The excision associated with a skin plasty was carried out. Histology concluded that there was a giant cerebriform naevo-cellular nevus of the scalp.

关键词： Giant Nevus Tumor of the Scalp Resection

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Advantages and disadvantages of nuclear reactions used in reactors or cyclotrons,in addition to a theoretical study based on photodisintegration on natural indium for^(111)Ag production

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Nuclear Science and Techniques 2022年第2期33卷 1-13页

作者： Khaled m.El-Azony Nader m.A.mohamed Dalal A.Aloraini Radioactive Isotopes and Generators Department Hot Labs.CenterEgyptian Atomic Energy AuthorityP.O.Box 13759CairoEgypt Reactors Department Egyptian Atomic Energy AuthorityP.O.Box 13759CairoEgypt Physics Department College of SciencePrincess Nourah Bint Abdulrahman UniversityRiyadhKingdom of Saudi Arabia

Production routes were recorded on available reactions for^(111)Ag production from nuclear reactors or cyclotrons using a natural palladium target based on^(110)Pd(n,γ)and^(110)pd(d,n)reactions,respectively.^(nat)Cd(γ,x)based on^(110)Cd(γ,p)has also been studied as a prospective reaction for the production of^(111)***,these nuclear reactions are difficult to utilize because,in some cases,they reduce the specific activity of^(111)*** is a consequence of the stable silver isotopes produced in high *** isotopes include^(107,109)Ag and,in other cases,the high impurity of silver radioisotopes,such as^(110)m,^(106)m,^(105)Ag,that are produced during parallel nuclear *** to a scarcity of data regarding the(γ,α)reaction,the gamma reaction on natural indium for^(111)Ag production based on the^(115)In(γ,α)reaction was *** ^(nat)In(γ,α)reaction satisfies the criteria as a possible reaction to produce^(111)Ag with a sufficient yield and purity as consequence of the high^(115)In(95.7%)abundance as an enriched form and a relatively soft background caused by the parallel nuclear reactions.

关键词： Silver-111 Nuclear data Natural cadmium Natural palladium Natural indium

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Citrus reticulata Blanco (the common mandarin) fruit:An updated review of its bioactive,extraction types,food quality,therapeutic merits,and bio-waste valorization practices to maximize its economic value

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Food Bioscience 2022年第3期47卷 67-80页

作者： mohamed Shorbagi Nesrin m.Fayek Ping Shao mohamed A.Farag Department of Special Chemistry Faculty of ScienceBenha UniversityAl Qalyubia GovernorateEgypt Pharmacognosy Department College of PharmacyCairo UniversityKasr El Aini st.11562CairoEgypt College of Food Science and Technology Zhejiang University of TechnologyZhejiangHangzhou310014PR China

Fruits are regarded as the richest dietary sources of polyphenols,carotenoids,terpenoids,and limonoids,making them highly desired prospects for the functional food *** waste that remains after fruit processing is also regarded as a valuable source of value-added phytochemicals.A comprehensive analysis of mandarin composition as a determinant of fruit functional properties,health benefits,and valorization into useful products is represented together with the effect of different processes such as light,wax coating,auxin addition,ozone treatment,and ethylene *** reviewing evidence is an essential precondition for improving the selling market of mandarin and highlighting its waste valorization potential and its incorporation into useful products produced by pharmaceutical *** this study,the phytochemical and biological reports presented to emphasize the needed priority for agricultural techniques to provide a certain mandarin product or *** addition,the paper summarizes the optimum conditions applied for the updated extraction techniques for phenolic acids,flavonoids,and oils at a commercial scale from mandarin peels and to enhance its global marketing.A brief representation is given towards potential mandarin patents and the valorization of its bio-waste fruits into commercial products of added *** review can guide researchers to produce future potentially marketed functional food enriched with mandarin extracts and/or bioactives.

关键词： Citrus reticulata Phytochemical composition Biological effects Waste valorization Extraction techniques Processing effect

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An Approximate Numerical methods for mathematical and Physical Studies for Covid-19 models

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Computer Systems Science & Engineering 2022年第9期42卷 1147-1163页

作者： Hammad Alotaibi Khaled A.Gepreel mohamed S.mohamed Amr m.S.mahdy Department of mathematics College of ScienceTaif UniversityTaif21944Saudi Arabia

The advancement in numerical models of serious resistant illnesses is a key research territory in different fields including the nature and the study of disease *** of the aims of these models is to comprehend the elements of conduction of these *** the new strain of Covid-19(Coronavirus),there has been no immunization to protect individuals from the virus and to forestall its spread so *** things being equal,control procedures related to medical services,for example,social distancing or separation,isolation,and travel limitations can be adjusted to control this *** article reveals some insights into the dynamic practices of nonlinear Coronavirus models dependent on the homotopy annoyance strategy(HPm).We summon a novel sign stream chart that is utilized to depict the Coronavirus *** the numerical investigations,it is uncovered that social separation of the possibly tainted people who might be conveying the infection and the healthy virus-free people can diminish or interrupt the spread of the *** mathematical simulation results are highly concurrent with the statistical *** free balance and dependability focus for the Coronavirus model is discussed and the presence of a consistently steady arrangement is demonstrated.

关键词： Covid-19 model optimal control existence of uniformly stable signal stream chart homotopy perturbation technique

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Controlled drainage in the Nile River delta of Egypt:a promising approach for decreasing drainage off-site effects and enhancing yield and water use efficiency of wheat

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Journal of Arid Land 2023年第4期15卷 460-476页

作者： mohamed K EL-GHANNAm Fatma WASSAR Sabah mORSY mohamed HAFEZ Chiter m PARIHAR Kent O BURKEY Ahmed m ABDALLAH Soil Water and Environment Research InstituteAgricultural Research CenterGiza 12112Egypt Higher Institute of Water Sciences and Techniques of Gabès University of GabèsGabès 6072Tunisia Institute of Arid Regions Medenine 4119Tunisia Crop Science Department Faculty of AgricultureDamanhour UniversityDamanhour 22516Egypt Land and Water Technologies Department Arid Lands Cultivation Research InstituteCity of Scientific Research and Technological ApplicationsNew Borg El-Arab 21934Egypt Indian Council of Agricultural Research(ICAR)-Indian Agricultural Research Institute(IARI) New Delhi 110012India United States Department of Agriculture(USDA)-Agricultural Research Services(ARS) Plant Science Research UnitNorth Carolina 27607USA Natural Resources and Agricultural Engineering Department Faculty of AgricultureDamanhour UniversityDamanhour 22516Egypt

North Africa is one of the most regions impacted by water *** implementation of controlled drainage(CD)in the northern Nile River delta of Egypt is one strategy to decrease irrigation,thus alleviating the negative impact of water *** study investigated the impacts of CD at different levels on drainage outflow,water table level,nitrate loss,grain yield,and water use efficiency(WUE)of various wheat *** levels of CD,i.e.,0.4 m below the soil surface(CD-0.4)and 0.8 m below the soil surface(CD-0.8),were compared with subsurface free drainage(SFD)at 1.2 m below the soil surface(SFD-1.2).Under each drainage treatment,four wheat cultivars were grown for two growing seasons(November 2018–April 2019 and November 2019–April 2020).Compared with SFD-1.2,CD-0.4 and CD-0.8 decreased irrigation water by 42.0%and 19.9%,drainage outflow by 40.3%and 27.3%,and nitrate loss by 35.3%and 20.8%,*** CD treatments,plants absorbed a significant portion of their evapotranspiration from shallow groundwater(22.0%and 8.0%for CD-0.4 and CD-0.8,respectively).All wheat cultivars positively responded to CD treatments,and the highest grain yield and straw yield were obtained under CD-0.4 *** the initial soil salinity as a reference,the soil salinity under CD-0.4 treatment increased two-fold by the end of the second growing season without negative impacts on wheat *** the drainage system by raising the outlet elevation and considering shallow groundwater contribution to crop evapotranspiration promoted water-saving and *** responses could be obtained based on the different plant tolerance to salinity and water stress,crop characteristics,and growth ***-specific soil salinity management practices will be required to avoid soil salinization due to the adoption of long-term shallow groundwater in Egypt and other similar agroecosystems.

关键词： drainage ratio nitrate loss water use efficiency yield soil salinity Nile River delta

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Optimal FOPID Controllers for LFC Including Renewables by Bald Eagle Optimizer

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Computers, materials & Continua 2022年第12期73卷 5525-5541页

作者： Ahmed m.Agwa mohamed Abdeen Shaaban m.Shaaban Department of Electrical Engineering College of EngineeringNorthern Border UniversityArar1321Saudi Arabia Electrical Engineering Department Faculty of EngineeringAl-Azhar UniversityCairo11651Egypt Department of Engineering Basic Science Faculty of EngineeringMenoufia UniversityShebin El-Kom32511Egypt

In this study,a bald eagle optimizer(BEO)is used to get optimal parameters of the fractional-order proportional-integral-derivative(FOPID)controller for load frequency control(LFC).SinceBEOtakes only a very short time in finding the optimal solution,it is selected for designing the FOPID controller that improves the system stability and maintains the frequency within a satisfactory range at different *** and demonstrations are carried out using *** performance of the BEOFOPID controller is evaluated using a two-zone interlinked power system at different loads and under uncertainty of wind and solar *** robustness of the BEO-FOPID controller is examined by testing its performance under varying system time *** results obtained by the BEOFOPID controller are compared with those obtained by BEO-PID and PID controllers based on recent metaheuristics optimization algorithms,namely the sine-cosine approach,Jaya approach,grey wolf optimizer,genetic algorithm,bacteria foraging optimizer,and equilibrium optimization *** results confirm that the BEO-FOPID controller obtains the finest result,with the lowest frequency *** results also confirm that the BEOFOPID controller is stable and robust at different loads,under varying system time constants,and under uncertainty of wind and solar energies.

关键词： Fractional order PID control load frequency control renewable energy bald eagle optimizer

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