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International Journal of Ophthalmology(English edition) 2020年第1期13卷 129-134页

作者： Amr Mounir Engy mohamed Mostafa Hatem Ammar Osama Ali Mohammed Alahmady Hamad Alsmman Mahmoud mohamed Farouk mohamed gamal elghobaier Department of Ophthalmology Sohag Faculty of MedicineSohag UniversitySohag 82524Egypt Egyptian Police Hospitals Cairo 11765Egypt

AIM: To evaluate the safety and efficacy of transepithelial photorefractive keratectomy(t-PRK) with adjuvant mitomycin C(MMC) versus femtosecond laser assisted keratomileusis(Femto-LASIK) in correction of high ***: Prospective randomized comparative study including 156 eyes of 156 patients with high myopia and a spherical equivalent refraction(SER) <-6.00 D. They were divided randomly into two groups: Group A included 72 eyes treated with t-PRK with adjuvant MMC and Group B included 84 eyes treated with Femto-LASIK. Visual acuity, SER, corneal topography, pachymetry and keratometry were assessed for 12 mo ***: The preoperative mean SER was-8.86±1.81 and-9.25±1.70 D in t-PRK MMC group and Femto-LASIK respectively(P=0.99) which improved to-0.65±0.43 D and-0.69±0.50 D at 12 mo follow up. Mean SER remained stable during the 12 mo of follow-up, with no statistically significant difference between the two groups(P=0.64). In t-PRK MMC group, only six eyes needed retreatment after six months of follow up. And two eyes showed haze(one reversible haze grade 2, while the other had dense irreversible haze grade 4).CONCLUSION: t-PRK MMC provides safe and satisfactory visual outcomes and acceptable risk as Femto-LASIK in patients with high myopia.

关键词： transepithelial photorefractive keratectomy femtosecond laser assisted keratomileusis high myopia corneal haze Egypt

Contemporary construction in historical sites:The missing factors

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Frontiers of Architectural Research 2024年第3期13卷 487-504页

作者： Sina Kamali Tabrizi mohamed gamal Abdelmonem School of Architecture Design and the Built EnvironmentNottingham Trent UniversityNottinghamUK Department of Architecture and the Built Environment University of YorkYorkUK

Historical sites(HSs)are akin to living entities,and their existence is perpetuated through the erection of new buildings or *** HSs need sustainable development and new construction,as existing monuments fail to meet contemporary user *** the urgent demand,many new buildings within HSs have been constructed without considering the influencing factors on contextual value,built,and natural *** oversight has led to irreversible damage to their historical *** studies have independently explored interventions,construction,and development within ***,there is a conspicuous absence of comprehensive research that concurrently addresses these issues while preserving the intrinsic value of the *** study aims to identify the variables and factors contributing to the successful design and construction of new buildings within HSs,satisfying user needs,conserving contextual values,and achieving sustainability with the natural and built *** research employs a mixed-method approach,gathering raw data through literature reviews,case studies,and expert *** study population comprised 97 experts in architectural heritage conservation and sustainable *** factor analysis was utilized for data analysis,leading to the identification of influential *** study highlights the significance of the location,function,scale,form,material,skyline,viewpoint,accessibility,reversibility,topography,sustainability,technology,structural system,lifespan,and interior design in constructing new buildings within a ***,the design of new additions should adhere to five guiding principles:integrated design,volume design,green design,compatible design,and modern *** this context,the new structures will fulfill user needs,preserve or enhance contextual values,and harmonize with the built and natural environment.

关键词： New building Contemporary construction Historical sites Sustainable development Architectural heritage

Jellyfish-inspired alginate composite hydrogel filter prepared by macro-micro double bionic strategy for efficient water purification

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Frontiers of Environmental Science & Engineering 2024年第4期18卷 141-157页

作者： Huiting Peng Yan Chen Jiaopan Lin Chelsea Benally mohamed gamal El-Din Junkai Gao School of Naval Architecture and Marinetime Zhejiang Ocean UniversityZhoushan 316022China Department of Civil and Environmental Engineering University of AlbertaEdmontonAB T6G 1H9Canada

Recently,research on hydrogel materials with a porous structure and superior water absorption capabilities significantly ***,the hydrogel under gravity-driven separation conditions often exhibit an unstable pore structure,poor mechanical properties,and limited *** this end,this work presents a novel approach that combines a macro-micro double bionic strategy with a triple crosslinking method to develop a multifunctional alginate composite hydrogel filter(2%-SA-κCG-PVA-Ca^(2+),2%-SKP-Ca^(2+)for short)with a stable pore structure and superior mechanical properties,which possessed an umbrella-shaped structure resembling that of *** 2%-SKPCa^(2+)filter was synthesized using polyvinyl alcohol(PVA)as a stable structure-directing agent,and sodium alginate(SA)andκ-carrageenan(κ-CG)as polymer *** distinctive umbrellashaped hydrogel of 2%-SKP-Ca^(2+)filter,formed through the triple crosslinking method,overcomes the limitations of unstable pore structure and poor durability seen in hydrogels prepared by traditional crosslinking ***,the utilization of the 2%-SKP-Ca^(2+)filter in water treatment demonstrates its good selective permeability,excellent resistance to fouling,and extended longevity,which enables it to simultaneously achieve the multifunctional water purification and the coating of multi-substrate anti-fouling ***,not only does this research provide an efficient,multifunctional,highly pollution-resistant preparation method for designing a new filter,but it also confirms the application prospect of the macro-micro dual bionic strategy developed in this study in complex water treatment.

关键词： Triple crosslinking method Alginate Umbrella-shaped Jellyfish Water purification

Experimental and theoretical insight into carbamazepine degradation by chlorine-based advanced oxidation processes:Efficiency,energy consumption,mechanism and DBPs formation

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Journal of Environmental Sciences 2024年第5期139卷 72-83页

作者： Chunwei Liu Zuo Tong How Yue Ju Li Feng Xuefeng Ren mohamed gamal El-Din Key Laboratory ofCoal Processing and Efficient Utilization of Ministry of Education School of Chemical Engineering and TechnologyChina University of Mining and TechnologyJiangsu 221116China Department of Civil and Environmental Engineering University of AlbertaEdmonton T6G 1H9AlbertaCanada School of Environment and Spatial Informatics China University of Mining and TechnologyJiangsu 221116China Key Laboratory of Agro-Forestry Environmental Processes and Ecological Regulation ofHainan Province School of Ecology and EnvironmentHainan UniversityHainan 570228China

Chlorine has been widely used in different advanced oxidation processes(AOPs)for micropollutants *** this study,different chlorine-based AOPs,namely medium pressure(MP)UV/chlorine,low pressure(LP)UV/chlorine,and in-situ chlorination,were compared for carbamazepine(CBZ)removal efficiency,energy consumption,and disinfection by-products(DBPs)*** three processes could achieve nearly 100%CBZ removal,while the reaction time needed by in-situ chlorination was double the time required by UV/chlorine *** energy consumed per magnitude of CBZ removed(EE/O)of MP UV/chlorine was 13 times higher than that of LP UV/chlorine,and relative to that of in-situ chlorination ***,MP and LP UV/chlorine processes generated one to two orders of magnitude more hydroxyl radicals(^(·)OH)and reactive chlorine species(RCS)than in-situ ***,RCS were the dominant reactive species,contributing to 78.3%,75.6%,and 71.6% of CBZ removal in MP,LP UV/chlorine,and in-situ chlorination,*** to the Gibbs free energy barriers between CBZ and RCS/^(·)OH calculated based on density functional theory(DFT),RCS had more reaction routes with CBZ and showed lower energy barrier in the main CBZ degradation pathways like epoxidation and formation of *** applied to secondary wastewater effluent,UV/chlorine and in-situ chlorination produced overall DBPs ranging from 104.77 to 135.41μg/***,the production of chlorate during UV/chlorine processes was 15 times higher than that during in-situ chlorination.

关键词： UV/chlorine In-situ chlorination Energy efficiency Role of reactive species DFT calculation Disinfection by-products

A statistical approach to enhance the productivity of Streptomyces baarensis MH-133 for bioactive compounds

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Synthetic and Systems Biotechnology 2024年第2期9卷 196-208页

作者： mohamed H.Kalaba gamal M.El-Sherbiny Osama M.Darwesh Saad A.Moghannem Botany and Microbiology Department Faculty of Science(Boys)Al-Azhar UniversityCairo 11884Egypt Agricultural Microbiology Department National Research CentreDokkiCairoEgypt

The goal of this study was to use statistical optimization to change the nutritional and environmental conditions so that Streptomyces baarensis MH-133 could make more active *** trials were used to screen for critical variables influencing productivity using the Placket-Burman Design *** MH-133 is significantly influenced by elicitation,yeast extract,inoculum size,and incubation period in terms of antibacterial activity.A total of 27 experimental trials with various combinations of these factors were used to carry out the response surface technique using the Box-Behnken *** analyses revealed that the model was highly significant(p<0.001),with a lack-of-fit of 0.212 and a coefficient determination(R2)of ***,the model predicted that the response as inhibition zone diameter would reach a value of 27 *** optimal conditions,*** MH-133 produced 18.0 g of crude extract to each 35L and was purified with column *** active fraction exhibiting antibacterial activity was characterized using spectroscopic *** MIC and MBC values varied between 37.5 and 300μg/ml and 75 and 300μg/ml,*** conclusion,the biostatistical optimization of the active fraction critical variables,including environmental and nutritional conditions,enhances the production of bioactive molecules by Streptomyces species.

关键词： S.baarensis MH-133 Placket-Burman designBox-Behnken design ESKAPE Antibacterial activity

Ultralong hydroxyapatite-based forward osmosis membrane for freshwater generation

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Frontiers of Chemical Science and Engineering 2024年第9期18卷 37-49页

作者： mohamed gamal Gomaa Hamdy Maamoun Abdel-Ghafar Francesco Galiano Francesca Russo Alberto Figoli El-Sayed Ali Abdel-Aal Abdel-Hakim Taha Kandil Bahaa Ahmed Salah Central Metallurgical Research and Development Institute(CMRDI) 11421 CairoEgypt Chemistry Department Faculty of ScienceHelwan University11795 CairoEgypt Institute on Membrane Technology(CNR-ITM) 87036 RendeItaly

Increasing global water shortages are accelerating the pace of membrane manufacturing,which generates many environmentally harmful *** challenges need a radical rethink of developing innovative membranes that can address freshwater production without generating environmentally harmful *** work utilized the synthesized ultra-long hydroxyapatite(UHA)by the solvothermal method using the green solvent oleic acid in preparing UHA-based forward osmosis *** membranes were developed using different loading ratios of graphene oxide(GO)by vacuum-assisted filtration *** prepared GO/UHA membranes were identified using X-ray diffraction,scanning electron microscope,Fourier-transform infrared spectroscopy,and X-ray photoelectron *** contact angle and pore size distribution were determined for the obtained GO/UHA *** obtained hierarchical porous structure in the prepared membranes with interconnected channels results in a stable water flux with reverse salt *** best water flux rate of 42±2 L·m^(–2)·h^(–1)was achieved using the 50 mg GO/UHA membrane,which is 3.3 times higher than the pristine membrane,and a reverse salt flux of 67 g·m^(-2)·h^(–1).The obtained results showed a promising capability of a new generation of sustainable inorganic-based membranes that can be utilized in freshwater generation by energy-efficient techniques such as forward osmosis.

关键词： forward osmosis ultra-long hydroxyapatite graphene oxide inorganic-based membrane

Asymptomatic bile duct stones:The devil is in the details

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World Journal of Gastrointestinal Endoscopy 2024年第5期16卷 227-231页

作者： Mohammed Omar Khalifa Elsayed mohamed gamal Talkhan Department of Gastroenterology South Tees Hospitals NHS Foundation TrustMiddlesbrough TS43BWUnited Kingdom

Common bile duct(CBD)stones are a common biliary tract *** asymp-tomatic CBD stones,stone removal by endoscopic retrograde cholangiopancreato-graphy(ERCP)is recommended in available *** asymptomatic CBD stones is a benign disease with no noticeable symptoms,the risk vs benefit strategy should be thoroughly considered before performing ERCP in these *** care review,technical aspects of the procedure,and patient preferences should also be considered.

关键词： Asymptomatic Common bile duct stones Endoscopic retrograde cholangiopancreatography Outcome Guidelines

Selenoprotein-p and insulin resistance in children and adolescents with obesity

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World Journal of Clinical Pediatrics 2024年第3期13卷 40-52页

作者： Amany Elbarky Kholoud gamal Ismail Yousef Fouad Yousef Rasha mohamed gamal Elshafiey Radwa Mahmoud Elsharaby Asmaa El-Kaffas Mohammed Al-Beltagi Gastroenterology and Clinical Nutrition Unit Pediatric DepartmentFaculty of MedicineTanta UniversityTanta 31511AlghrabiaEgypt Department of Pediatric Faculty of MedicineTanta UniversityTanta 31511AlghrabiaEgypt Department of Clinical Pathology Faculty of MedicineTanta UniversityTanta 31511AlghrabiaEgypt Department of Paediatric University Medical CenterKing Abdulla Medical CityArabian Gulf UniversityManama 26671ManamaBahrain

BACKGROUND Insulin resistance and obesity present significant challenges in pediatric *** P1(SEPP1)serves as a biomarker for assessing selenium levels in the *** its association with metabolic syndrome is established in adults,its relevance in children remains *** To ascertain SEPP1 blood levels in children and adolescents diagnosed with obesity and to assess its correlation with insulin resistance and adiposity *** 170 children participated in this study,including 85 diagnosed with obesity and an equal number of healthy counterparts matched for age and *** participant underwent a comprehensive medical evaluation,encompassing a detailed medical history,clinical examination,and anthropometric measurements like waist circumference and waist-to-height ***,routine blood tests were conducted,including serum SEPP1,visceral adiposity index(VAI),and Homeostatic Model Assessment of Insulin Resistance(HOMA-IR)*** Our findings revealed significantly lower serum SEPP1 levels in children with obesity compared to their healthy ***,notable negative correlations were observed between serum SEPP1 levels and body mass index,VAI,and *** The study suggests that SEPP1 could serve as a valuable predictor for insulin resistance among children and adolescents diagnosed with *** highlights the potential utility of SEPP1 in pediatric metabolic health assessment and warrants further investigation.

关键词： Obesity Childhood obesity Selenium status Selenoprotien P1 Insulin resistance

A coal rib monitoring study in a room-and-pillar retreat mine

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International Journal of Mining Science and Technology 2021年第1期31卷 127-135页

作者： gamal Rashed Khaled mohamed Robert Kimutis GCB/PMRD//NIOSH/CDC PittsburghPA 15236USA

The National Institute for Occupational Safety and Health(NIOSH)conducted a comprehensive monitoring program in a room-and-pillar mine located in Southern *** deformation and the stress change in an instrumented pillar were monitored during the progress of pillar retreat mining at two sites of different geological conditions and depths of *** main objectives of the monitoring program were to better understand the stress transfer and load shedding on coal pillars and to quantify the rib deformation due to pillar retreat mining;and to examine the effect of rib geology and overburden depth on coal rib *** instrumentation at both sites included pull-out tests to measure the anchorage capacity of rib bolts,load cells mounted on rib bolts to monitor the induced loads in the bolts,borehole pressure cells(BPCs)installed at various depths in the study pillar to measure the change in vertical pressure within the pillar,and roof and rib extensometers installed to quantify the vertical displacement of the roof and the horizontal displacement of the rib that would occur during the retreat mining *** outcome from the monitoring program provides insight into coal pillar rib support optimization at various depths and geological ***,this study contributes to the NIOSH rib support database in U.S coal mines and provides essential data for rib support design.

关键词： Coal rib performance Coal rib design Coal rib monitoring Coal rib failure Load transfer Retreat mining

Loading characteristics of mechanical rib bolts determined through testing and numerical modeling

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International Journal of Mining Science and Technology 2020年第1期30卷 17-24页

作者： Khaled mohamed gamal Rashed Zorica Radakovic-Guzina Centers for Disease Control National Institute for Occupational Safety and HealthPittsburghPA 15236USA ITASCA Consulting Group MinneapolisMN 55401USA

Underground coal mines use mechanical bolts in addition to other types of bolts to control the rib deformation and to stabilize the yielded coal *** research has been conducted to understand the performance of the mechanical bolts in coal *** from the National Institute for Occupational Safety and Health(NIOSH)conducted this work to understand the loading characteristics of mechanical bolts(stiffness and capacity)installed in coal ribs at five underground coal *** pull-out tests were performed in this study to define the loading characteristics of mechanical rib *** installation torques were applied to the tested bolts based on the strength of the coal seam.A typical tri-linear load-deformation response for mechanical bolts was obtained from these *** was found that the anchorage capacity depended mainly on the coal *** for modeling mechanical bolts have been developed using the tri-linear load-deformation *** outcome of this research provides essential data for rib support design.

关键词： Coal rib Mechanical bolt Conventional bolt Tension bolt Point-anchored bolt Rib support Pull-out test Numerical modeling FLAC3D