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Palinopsia as a Rare Presenting Symptom of Occipital Stroke “Case Report”

Case Reports in Clinical Medicine 2021年第7期10卷 203-212页

作者： Muaz Abdellatif Elsayed mohamed atif makdum Sheena Shirmilon Salim Nuzrath Salmin Abdul Razak University Hospital Sharjah Sharjah UAE

Palinopsia is the recurrence or persistence of visual images after cessation of the stimulus. Palinopsia has been associated with a wide variety of etiologies and mechanisms such as drug induced, seizures, migraine, psychiatric conditions, head trauma and structural lesions in the brain. We report a case of occipital stroke who presented with oscillating palinopsia. Sudden-onset palinopsia is a very rare symptom of stroke, but it must be recognized early as it is a highly time dependent, and potentially treatable condition. A 57-year-old woman with a history of poorly controlled type 2 diabetes, hyperlipidemia, and hypertension presented with sudden onset right sided palinopsia with images of her face and right forearm with hand, occurring several times in a day, lasting for a few minutes each time, and appearing in the same location each time. There are few case reports in literature secondary to stroke and what makes it interesting also is that she reported persistence of image even when her eyes are closed. Moreover, the sudden onset is not common in literature. The Magnetic Resonance Imaging (MRI) of the brain showed evidence of left Posterior Cerebral Artery (PCA) territorial (Fusiform gyrus) subacute ischemic infarction. Visual field assessment showed a right homonymous hemianopia. She was treated with aspirin and clopidogrel. The frequency and intensity of palinopsia reduced subsequently. The face image disappeared in the first week while the forearm image disintegrated gradually over the next few weeks. Palinopsia may be a rare presenting symptom of stroke. It is important for the clinician or emergency room doctors to be alert to the possibility of undiagnosed structural neurological lesions like occipital stroke and differentiate it from non-organic causes, as prompt management may reduce the risk of visual or motor disability.

关键词： Palinopsia Oscillating Occipital Stroke Hemianopia Case Report

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Terlipressin and hepatorenal syndrome: What is important for nephrologists and hepatologists

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World Journal of Gastroenterology 2010年第41期16卷 5139-5147页

作者： Ahmed A Magan atif A Khalil mohamed H Ahmed Department of Surgery Cambridge Uni-versity Hospital NHS foundation Trust Hills Road Cambridge CB2 0QQ United Kingdom Department of Nephrology Royal Liverpool and Broadgreen University Hospitals Liverpool L7 8XP United Kingdom Division of Acute Medicine James Cook University Hospital Marton Road Middlesbrough TS4 3BW United Kingdom

Hepatorenal syndrome (HRS) is a reversible form of functional renal failure that occurs with advanced hepatic cirrhosis and liver failure. Despite mounting research in HRS, its etiology and medical therapy has not been resolved. HRS encompasses 2 distinct types. Type 1 is characterized by the rapid development of renal failure that occurs within 2 wk and involves a doubling of initial serum creatinine. Type 2 has a more insidious onset and is often associated with ascites. Animal studies have shown that both forms, in particular type 1 HRS, are often precipitated by bacterial infections and cir-culatory changes. The prognosis for HRS remains very poor. Type 1 and 2 both have an expected survival time of 2 wk and 6 mo, respectively. Progression of liver cir-rhosis and the resultant portal hypertension leads to the pooling of blood in the splanchnic vascular bed. The ensuing hyperdynamic circulation causes an ineffective circulatory volume which subsequently activates neuro-hormonal systems. Primarily the sympathetic nervoussystem and the renin angiotensin system are activated, which, in the early stages of HRS, maintain adequate circulation. Both advanced cirrhosis and prolonged ac-tivation of neurohormonal mechanisms result in fatal complications. Locally produced nitric oxide may have the potential to induce a deleterious vasodilatory effect on the splanchnic circulation. Currently medical therapy is aimed at reducing splanchnic vasodilation to resolve the ineffective circulation and maintain good renal per-fusion pressure. Terlipressin, a vasopressin analogue, has shown potential benefit in the treatment of HRS. It prolongs both survival time and has the ability to re-verse HRS in the majority of patients. In this review we aim to focus on the pathogenesis of HRS and its treatment with terlipressin vs other drugs.

关键词： Heptorenal syndrome Terlipressin Kidney Liver

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Coronavirus disease 2019 and renal transplantation

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World Journal of Clinical Cases 2021年第27期9卷 7986-7997页

作者： Mahmoud Nassar Nso Nso Jonathan Ariyaratnam Jasmine Sandhu Mahmoud mohamed Bahaaeldin Baraka atif Ibrahim Mostafa Alfishawy David Zheng Harangad Bhangoo Karim M Soliman Matthew Li Vincent Rizzo Ahmed Daoud Department of Medicine Icahn School of Medicine at Mount Sinai(NYC Health and Hospitals:Queens)New YorkNY 10029United States Department of Medicine University of Tennessee Health Science CenterMemphisTN 38163United States Department of Oncology Southend University HospitalNHS Foundation TrustEssex SS00RYUnited Kingdom Renal Division Department of MedicineUniversity of Tennessee Health Science CenterMemphisTN 38163United States Infectious Diseases Infectious Diseases Consultants and Academic Researchers of Egypt IDCARECairo 0000Egypt Department of Medicine Medical University of South CarolinaCharlestonSC 29425United States Department of Clinical Pharmacy Icahn School of Medicine at Mount Sinai(NYC Health and Hospitals:Queens)New YorkNY 10029United States Department of Medicine Icahn School of Medicine at Mount Sinai(NYC Health and Hospitals:Queens)New YorkNY 11373United States Department of Medicine Kasr Alainy Medical SchoolCairo UniversityCairo 11562Egypt

Ever since the severe acute respiratory syndrome virus causing coronavirus disease 2019(COVID-19)struck the world,global health strategies have changed *** to the Centers for Disease Control and Prevention,kidney transplant recipients are stratified as being high risk of developing fatal illness from COVID-19 *** transplant is the gold-standard treatment for end-stage kidney disease *** the pandemic,significant concerns have emerged regarding continuation of kidney transplant surgeries and management of kidney transplant recipients *** added risk of immunosuppression in this cohort was and remains a theoretical concern,posing a potential risk of transplantation rather than *** comprehensive review aims to cover most of the faced challenges in kidney transplantation in different stages of the *** addition,it will elucidate the epidemiology,nature,course of the disease,surgical consideration in donors and recipients as well as role of immunosuppression and management of COVID-19 infected kidney transplant recipients during these extraordinary circumstances.

关键词： Renal transplantation COVID-19 SARS-CoV-2 Kidney failure

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Role of Antioxidants in Female Fertility

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Open Journal of Obstetrics and Gynecology 2018年第2期8卷 85-91页

作者： Amal Al Mulla atif B. E. Fazari mohamed Elkhouly Natalie Moghaddam Dubai Fertility & Gynecology Center Dubai UAE Latifa Hospital Dubai Health Authority Dubai UAE University of Medical Sciences & Technology Faculty of Medicine Khartoum Sudan Bourn Hall Fertility Centre Dubai UAE

The last decade has seen a noticeable advance in diagnosing and treating infertility, however, the overall incidence has remained the same, with an estimated 40% - 50% resulting from factors related to the female [1]. Unexplained infertility where the cause remains elusive, still accounts for up to 30% of cases. Increasing evidence demonstrates the significant of antioxidants in all physiological and biochemical processes in humans, including human reproduction.

关键词： Female Fertility Antioxidants Free Rdaicals Reactive Oxygen Species Assisted Reproductive Technique

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Eltrombopag Managed Severe Immune Thrombocytopenic Purpura in Pregnancy: A Case Report, Latifa Hospital, DHA, Dubai, UAE

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Open Journal of Obstetrics and Gynecology 2019年第7期9卷 991-996页

作者： Komal Sundeep Hazari atif Bashir E. Fazari Taghrid Gergawi Hasan mohamed A. Aal-Yaseen Nighat Aftab Department of Obstetrics & Gynecology Latifa Hospital DHA Dubai UAE Faculty of Medicine University of Medical Sciences & Technology Khartoum Sudan Department of Medicine Clinical Haematology Dubai Hospital DHA Dubai UAE

Immune thrombocytopenic purpura (ITP) is an acquired autoimmune disorder, defined by a platelet count of less than 100 × 109/L, secondary to impaired production and immune destruction of platelets. Bleeding tendency is the main presentation of this condition. Clinical symptoms and investigations will confirm the diagnosis. Steroid is the first line of treatment. Although Rituximab and Thrombopoietin receptor agonists are useful second line agents in non-pregnant adults, the data about their role in pregnancy are still limited. We present the case of a 30 year old primigravida, who was a known case of chronic ITP since childhood;the course of her disease was fluctuating, for which oral steroids were used accordingly. She presented with gum bleeding and petechial rash with very low platelets count. She was sponsored by the Patient Support Program and was given Eltrombopag during the third trimester. She responded well to Eltrombopag with no noticeable side effects, neither to the mother nor to the baby so far. Eltrombopag has been assigned Category C by the Federal Drugs Agency (FDA) nevertheless there are no well controlled data in the literature about its role in pregnancy.

关键词： Immune Thrombocytopenic Purpura Eltrombopag Pregnancy

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Ovarian Vein Thrombosis, Critical Diagnosis at Al-Hasahisa Obstetrics & Gynecology Teaching Hospital in Geziera State, Sudan

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Open Journal of Obstetrics and Gynecology 2023年第6期13卷 1020-1024页

作者： mohamed ElAmin M. A. Elkhazein atif B. E. Fazari mohamed Bakry Habeeb Parveen B. Mohammed Elrasheed H. A. Mohammed Al-Hasahisa Obstetrics & Gynecology Teaching Hospital Rufaa Sudan Faculty of Medicine Albutana University Rufaa Sudan Latifa Hospital DHA Dubai UAE Faculty of Medicine University of Medical Sciences & Technology Khartoum Sudan

Ovarian vein thrombosis (OVT) is a rare thrombotic condition commonly attributed to the puerperium. The complications of OVT can be significant, and diagnosis relies on a high clinical index of suspicion. It can occur with lower quadrant pain that may mimic a surgical abdomen, especially in the setting of recent pregnancy, abdominal surgery, inflammatory disease, or malignancy. Diagnosis can be made with confidence using ultrasound, computed tomography, or magnetic resonance imaging. Management of OVT is particularly important in postpartum patients, with anticoagulation therapy being the treatment of choice.

关键词： Ovarian Vein Thrombosis Puerperium Pregnancy

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Viral respiratory infections among Hajj pilgrims in 2013

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Virologica Sinica 2014年第6期29卷 364-371页

作者： Osamah Barasheed Harunor Rashid Mohammad Alfelali mohamed Tashani Mohammad Azeem Hamid Bokhary Nadeen Kalantan Jamil Samkari Leon Heron Jen Kok Janette Taylor Haitham El Bashir Ziad A.Memish Elizabeth Haworth Edward C.Holmes Dominic E Dwyer atif Asghar Robert Booy National Centre for Immunisation Research and Surveillance (NCIRS) The Children’s Hospital at WestmeadNSWAustralia Department of Family and Community Medicine Faculty of MedicineKing Abdulaziz UniversityRabighSaudi Arabia The Custodian of the two Holy Mosques Institute for Hajj and Umrah Research Umm Al-Qura UniversityMakkahSaudi Arabia King Abdulaziz Medical City JeddahSaudi Arabia Centre for Infectious Diseases and Microbiology Laboratory Services Westmead HospitalNSWAustralia Hamad Medical Corporation DohaQatar Ministry of Health RiyadhSaudi Arabia Menzies Research Institute Tasmania HobartTasmaniaAustralia Sydney Medical School The University of SydneyNSWAustralia Marie Bashir Institute for Infectious Diseases and Biosecurity The University of SydneyNSWAustralia

Middle East respiratory syndrome coronavirus(MERS-Co V) has emerged in the Arabian Gulf region, with its epicentre in Saudi Arabia, the host of the ‘Hajj' which is the world's the largest mass gathering. Transmission of MERS-Co V at such an event could lead to its rapid worldwide dissemination. Therefore, we studied the frequency of viruses causing influenza-like illnesses(ILI) among participants in a randomised controlled trial at the Hajj 2013. We recruited 1038 pilgrims from Saudi Arabia, Australia and Qatar during the first day of Hajj and followed them closely for four days. A nasal swab was collected from each pilgrim who developed ILI. Respiratory viruses were detected using multiplex RT-PCR. ILI occurred in 112/1038(11%) pilgrims. Their mean age was 35 years, 49(44%) were male and 35(31%) had received the influenza vaccine pre-Hajj. Forty two(38%) pilgrims had laboratory-confirmed viral infections; 28(25%) rhinovirus, 5(4%) influenza A, 2(2%) adenovirus, 2(2%) human coronavirus OC43/229 E, 2(2%) parainfluenza virus 3, 1(1%) parainfluenza virus 1, and 2(2%) dual infections. No MERS-Co V was detected in any sample. Rhinovirus was the commonest cause of ILI among Hajj pilgrims in 2013. Infection control and appropriate vaccination are necessary to prevent transmission of respiratory viruses at Hajj and other mass gatherings.

关键词： Hajj influenza-like illness mass gathering MERS-CoV pilgrim respiratory infections

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Effect of aortic valve replacement on ventricular recovery and functional class in patients with reduced left ventricular function

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World Journal of Cardiovascular Diseases 2013年第9期3卷 543-550页

作者： Mahdi Ait Houssa Younes Moutakiallah Abdessamad Abdou Abdedaim Hatim mohamed Drissi Brahim Amahzoune Youssef El Bekkali atif Benyass Abdelatif Boulahya Cardiac Surgery Department Mohammed V Military HospitalRabatMorocco ICU of Cardiac Surgery Department Mohammed V Military HospitalRabatMorocco Cardiology Department Mohammed V Military HospitalRabatMorocco

Objective: The aim of the study was to assess the effects of aortic valve replacement (AVR) in patients with aortic stenosis (AS) or regurgitation (AR) and left ventricular (LV) dysfunction. Patients and methods: Retrospective analysis identified 75 consecutive patients with left ventricular ejection fraction (LVEF) assessed by echocardiography < 40% who underwent AVR for AS (n = 40) or AR (n = 35) between 1994 and 2011. Exclusion criteria were previous myocardial infarction or concomitant valvular disorders other than aortic disease. Follow-up evaluated the New York Heart Association (NYHA) functional class, LVEF and survival rate. Results: Mean ages were respectively 56.5 ± 9.3 and 47.9 ± 11.7 years in AS and AR groups, p = 0.001. Before surgery, 88% and 75% of patients were in NYHA III-IV respectively in AS and AR. In the AS group, the mean LVEF and aortic valve area (AVA) were respectively 32.2% ± 8% and 0.65 ± 0.15 cm2. AR group had a mean LVEF of 33.8 ± 6.7% and a mean LV systolic diameter of 62 ± 8.8 mm. All patients underwent AVR under cardiopulmonary bypass. There were 5 operative deaths (12.5%) in AS group and 6 (17.6%) in AR group, p = 0.57. LVEF increased to 49% ± 14.7% and 51.2% ± 10.9% in the AS and AR groups after echocardiography control. The survival rates at 1, 5 and 10 years were respectively 94.4%, 87% and 80% in AS group and 95.2%, 93% and 89% in AR group. Conclusion: Despite higher perioperative mortality in patients with aortic valve disease (AS or AR) and LV dysfunction, long-term outcome is excellent. We, therefore, conclude that AVR can be performed and it should not be denied to patients on the basis of low EF alone.

关键词： Aortic Valve Disease Aortic Valve Replacement Left Ventricular Dysfunction

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The Impact of Behavioural Insights on Effective Prescription of Antibiotics by Doctors: A Case Study from Latifa Hospital for Women and Children, Dubai Health Authority

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Health 2023年第6期15卷 517-524页

作者： Muna A. Tahlak atif B. Fazari Fareeda Khan Raid Abukaf Lyla G. Zadeh Alawi Alsheikh Abdulaziz Istaitieh Latifa Hospital for Women and Children Dubai Health Authority Dubai UAE mohamed Bin Rashid University Dubai UAE Mohammed Bin Rashid School of Government Dubai UAE

Introduction: Wise prescription of antibiotics is an ethical duty of physicians in view of rising antimicrobial resistance in the community, it should be balanced between the health requirements of the patients and resulting long-term antibiotics resistance. Overuse of antimicrobials is a major cause of emerging resistance to antimicrobials. There are multiple factors in the community that influence the physician’s antibiotic prescriptions. Methods: This is a systematic case-control study on antibiotics prescription for paediatric patients attending Latifa Hospital for Women and Children (LWCH), Dubai Health Authority, to know the effects of behavioral interventions on rates of inappropriate antimicrobials prescription by doctors in the Paediatric Emergency Department. Results: The results of our study showed the effectiveness of behavioral insights by peer comparison in antibiotic use among paediatricians in Latifa Hospital had a statistical significance (P = 0.0038). The rate of the prescription decreased from 41% to 21%, a difference of 20%. Conclusion: The study concluded behavioural intervention is an effective measure in reducing the improper prescription of antibiotics in the hospital setting.

关键词： Behavioural Intervention Antibiotics Prescription Behavioral Economics Health Economics Behavioural Insight

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How does epidemiological and clinicopathological features affect survival after gastrectomy for gastric cancer patientssingle Egyptian center experience

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World Journal of Gastrointestinal Surgery 2016年第6期8卷 444-451页

作者： Ehab El Hanafy Ayman El Nakeeb Helmy Ezzat Emad Hamdy Ehab atif Tharwat Kandil Amgad Fouad mohamed Abdel Wahab Ahmed Monier Gastroenterology Surgical Center Mansoura University

AIM:To investigate the clinicopathological features and the significance of different prognostic factors which predict surgical overall survival in patients with gastric ***:This retrospective study includes 80 patients diagnosed and treated at gastroenterology surgical center,Mansoura University,Egypt between February 2009 to February *** factors were assessed by cox proportional hazard ***:There were 57 male and 23 *** median age was 57 years(24-83).One,3 and 5 years survival rates were 71%,69% and 46% *** median survival was 69.96 *** the follow-up period,13 patients died(16%).Hospital morbidity was reported in 10 patients(12.5%).The median number of lymph nodes removed was 22(4-41).Lymph node(LN) involvement was found in 91% of *** R0 resection,depth of wall invasion,LN involvement and the number(> 15) of retrieved LN,LN ratio and tumor differentiation predict *** multivariable analysis,tumor differentiation,curability of resection and a number of resected LN superior to 15 were found to beindependent prognostic ***:Surgery remains the cornerstone of *** differentiation,curability of resection and a number of resected LN superior to 15 were found to be independent prognostic *** LN dissection does not increase the morbidity or mortality rate but markedly improves long term survival.

关键词： Cancer stomach Prognostic factors Lymph node metastasis Recurrence after gastrectomy Lymph node ratio

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