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Salivary C-reactive protein and mean platelet volume as possible diagnostic markers for late-onset neonatal pneumonia

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World Journal of Clinical Pediatrics 2024年第1期13卷 41-51页

作者： Wafaa ahmed Metwali abdelrahman mohamed Elmashad Sahar Mohey Eldin Hazzaa Mohammed Al-Beltagi mohamed Basiony Hamza Department of Pediatric Faculty of MedicineTanta UniversityTanta 31511AlgahrbiaEgypt Department of Clinical Pathology Faculty of MedicineTanta UniversityTanta 31511AlgahrbiaEgypt Department of Pediatric University Medical CenterDr.Suliaman Al Habib Medical GroupManama 26671ManamaBahrain Department of Pediatric University Medical CenterKing Abdulla Medical CityArabian Gulf UniversityManama 26671ManamaBahrain

BACKGROUND Neonatal sepsis,a formidable threat to newborns,is a leading cause of neonatal mortality,with late-onset sepsis manifesting after 72 hours post-birth being particularly ***,a prevalent sepsis presentation,poses a significant risk,especially during the neonatal phase when lung defenses are *** diagnosis of pneumonia is imperative for timely and effective ***,a minimally invasive diagnostic medium,holds great promise for evaluating infections,especially in *** To investigate the potential of serum C-reactive protein(CRP),salivary CRP(sCRP),and mean platelet volume(MPV)as diagnostic markers for late-onset neonatal pneumonia(LONP).METHODS Eighty full-term neonates were systematically examined,considering anthropometric measurements,clinical manifestations,radiology findings,and essential biomarkers,including serum CRP,sCRP,and *** The study reveals noteworthy distinctions in serum CRP levels,MPV,and the serum CRP/MPV ratio between neonates with LONP and healthy *** exhibited a robust discriminatory ability[area under the curve(AUC)=0.87]with high sensitivity and specificity at a cutoff value of>*** between serum CRP,sCRP,and MPV were also ***,sCRP demonstrated excellent predictive value for serum CRP levels(AUC=0.89),underscoring its potential as a diagnostic *** This study underscores the diagnostic promise of salivary and serum biomarkers,specifically MPV and CRP,in identifying and predicting LONP among *** findings advocate for further research to validate their clinical utility in larger neonatal cohorts.

关键词： Neonatal sepsis Late-onset pneumonia Salivary C-reactive protein Mean platelet volume Diagnostic markers Newborn infections

Sero-Prevalence and Risk factors of Contagious Bovine Pleuropneumonia (CBPP) in Afgoye District Lower Shabelle Region, Somalia

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Open Journal of Veterinary Medicine 2024年第2期14卷 11-20页

作者： ahmed mohamed ahmed Sumaya Hassan Ali Abdisalam mohamed Ali Abdirazack Saleban Osman Binti Abubakar mohamed Abdifatah Mohamud Ibar Shafii Abdullahi mohamed mohamed abdelrahman mohamed ahmed Ali Omar Zakaria Ibrahim Issack College of Veterinary Medicine Abrar University Mogadishu Somalia Faculty of Veterinary Medicine and Animal Husbandry Somali National University Mogadishu Somalia Faculty of Veterinary Science Benadir University Mogadishu Somalia

Contagious bovine Pleuropneumonia (CBPP) is an infectious and highly contagious respiratory disease of cattle and water buffalo, caused by the Mycoplasma mycoides subspecies mycoides. It induces significant economic losses and leads to a severe livestock production problem, negatively influencing people’s livelihoods of affected countries. In Somalia, there is no updated data on the prevalence and distribution of the disease. Hence, a descriptive cross-sectional study was conducted from September 2022 to June 2023 in different villages under the Afgoye District of lower Shabelle region, Somalia. The main purpose of this study is to assess the sero-prevalence and identify the associated risk factors for the occurrence of the disease. In this study, villages, age, sex, breed, and body condition were considered as risk factors. A total of 90 blood samples were collected and tested in the laboratory using the Anti-CBPP Elisa kit test. Out of 90 serum samples from herd cattle, 32 were positive, resulting in an overall prevalence of 35.5%. In addition, we found a statistically significant variation between the prevalence of the disease and factors such as sex, age, body condition and breeds. In summary, the overall prevalence of Contagious bovine pleuropneumonia in this study area is worth to be considered because there is a low quality of health care and less awareness of the Contagious bovine Pleuropneumonia effects on herds, which warrants the official authorities to act and follow appropriate preventive and control measures to reduce the incidence of the disease and generate appropriate controlling and prevention measures in all regions of Somalia.

关键词： Contagious Bovine Pleuropneumonia Sero-Prevalence Cattle Somalia Mycoplasma Cross Sectional Study

Hematological picture of pediatric Sudanese patients with visceral leishmaniasis and prediction of leishmania donovani parasite load

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World Journal of Clinical Cases 2024年第30期12卷 6374-6382页

作者： Zeinab Ibrahim ahmed Elnoor Omaima Abdelmajeed Alamin Mustafa Thuraya Gasim Shima Algam mohamed Musa abdelrahman Hamza Abdelmoneim Islamia Ibrahim ahmed Omer Hiba Awadelkareem Osman Fadl Department of Pathology Faculty of MedicineOmdurman Ahilia UniversityOmdurmanKhartoumSudan Mohammed Alamin Hamid Pediatric Hospital Omdurman KhartoumSudan Department of Hematology and Blood Transfusion Medicine Federal Ministry of HealthKhartoumSudan Department of Pediatrics Faculty of MedicineOmdurman Islamic UniversityOmdurmanKhartoumSudan Tropical Diseases Teaching Hospital OmdurmanKhartoumSudan Faculty of Medicine Al-Neelain UniversityKhartoumSudan Faculty of Medicine Omdurman Islamic UniversityOmdurmanKhartoumSudan Department of Pediatrics Faculty of MedicineUniversity of Science and TechnologyKhartoumSudan Department of Hematology Faculty of Medical Laboratory SciencesAl-Neelain UniversityKhartoumSudan

BACKGROUND Visceral leishmaniasis(VL)is a systemic protozoan infection caused by Leishmania donovani(***)and transmitted by sand flies,causing macrophage invasion in the liver,spleen,and bone *** of VL is currently based on clinical signs,symptoms,and specific in-vitro markers and bone marrow ***,VL's specific hematological and bone marrow manifestation in Sudanese pediatric patients is not well *** To examine the blood and bone marrow characteristics in pediatric patients from Sudan who have *** This is a retrospective hospital-based study with a sample of 107 consecutive Sudanese pediatric *** data focused on hematological and bone marrow *** included only the completed records of the pediatric patients with VL in the Tropical Disease Teaching Hospital in Khartoum,Sudan from the period of 2016 to *** The majority of pediatric patients included in this study are below 5-years-old(n=59,55.2%).Moreover,anemia,thrombocytopenia,and leukopenia were among the prevalent characteristics in the population under *** further analyze the data,we developed a machine learning model using boosted forest algorithms to predict *** parasites load,with a mean accuracy of 0.88 for the training dataset and an accuracy of 0.46,0.50,and 0.74 for mild,moderate,and severe *** parasite load in the validation *** This study shows that the most common bone marrow change among Sudanese VL children was increased chronic inflammatory cells(n=88,82.2%)with present macrophage hemophagocytes(n=103,96.3%).While anemia and thrombocytopenia were the most common hematological *** results will hopefully lead to an early diagnosis and hence better management for Sudanese pediatric patients with suspected VL.

关键词： Machine learning Bone marrow Hematological changes Tropical diseases Leishmania donovani Visceral leishmaniasis

Evaluation of implanted perforated lacrimal punctal plugs using anterior segment optical coherence tomography

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Eye and Vision 2021年第1期8卷 366-373页

作者： Raafat Mohyeldeen abdelrahman Abdallah ahmed mohamed Kamal Elshafei Heba Radi AttaAllah Ophthalmology Department Minia UniversityEl‑MiniaEgypt Ophthalmology Department Minia University HospitalEl‑MiniaEgypt

Purpose:Evaluation of the patency and position of perforated lacrimal punctal plugs implanted for treating punctal stenosis together with quantitative assessment of the precorneal tear film using anterior segment optical coherence tomography(AS-OCT).Methods:In a prospective study,the lower punctum of 54 eyes of 29 patients implanted with perforated punctal plugs were examined using AS-OCT during the early postoperative *** tear meniscus height(TMH)and tear meniscus area(TMA)were ***,the patency of the plug,its position,TMH and TMA were evaluated,and the results were correlated with postoperative *** scale was used for epiphora ***:Using AS-OCT,48(88.9%)plugs were found in proper position while 6(11.1%)were *** lumen of the plugs was completely patent in 47(87%)plugs,partially obstructed in 2(3.7%)plugs and completely occluded in 5(9.2%)*** was a statistically significant postoperative decrease of TMH and TMA(P<0.001)and postoperative epiphora Munk score(P<0.001).Conclusion:AS-OCT is a valuable,reliable,and noninvasive investigative tool that can detect the proper positioning,patency,and contents of the implanted perforated lacrimal punctal plugs in addition to measurement of TMH and TMA.

关键词： AS-OCT Perforated plugs Plugs

Techno-economic analysis to develop the first wind farm in the Egyptian western desert at Elkharga Oasis

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Clean Energy 2022年第1期6卷 211-225页

作者： mohamed A.abdelrahman Radwan H.Abdel-Hamid Maged ahmed Abo Adma mohamed Daowd Electrical Power and Machines Department Faculty of EngineeringHelwan UniversityCairoEgypt

During the past few years,Egypt has increased the share of electricity generation from renewable energy sources to achieve the renewable-energy *** Egyptian Ministry of Electricity and Renewable Energy has set an ambitious target to increase the share of renewable energy among the total energy mix to be 20%by 2022 and 42%by *** target will be achieved using several approved policies such as feed-in tariffs,build-own-operate and independent power producers under a merchant *** paper presents a full analysis of wind-potential characteristics at Elkharga Oasis in Egypt based on an actual wind-measurement campaign taken by a met mast at two height levels of 10 and 25 m,*** measurements show an average annual wind speed of 5.72 m/s at 10-m height and 6.53 m/s at>25-m *** estimated wind speed,however,is 8.38 m/s at 120 m,which is technically convenient to generate electricity from wind *** this paper,the wind potential in the area is assessed using the statistical method of the Weibull probability density *** different methods to estimate the Weibull distribution parameters are presented and the relevant accuracy is verified based on the root mean square error.A techno-economic assessment and selection of the optimal wind-turbine size with ideal micro-sitings are performed using the software package *** cases of study for three typical wind-turbine models with various rotor diameters,power capacity,layout configuration and annual yield are assessed at the *** selection of the most convenient wind turbine is determined based on the IEC 61400 standard criteria and the turbine that produces the lowest levelized cost of electricity.

关键词： wind energy wind-resource assessment Weibull distribution windPRO levelized cost of electricity

The Utilization of Eucalyptus Oil for Reducing Methane Production in Ruminants under in Vitro Conditions

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The Utilization of Eucalyptus Oil for Reducing Methane Produ...

作者： Safwat mohamed abdelrahman ahmed Attia 吉林农业大学

学位级别：硕士

畜牧业产生的甲烷是引起全球变暖的主要因素。地球气候变暖成为全球重要问题之一。本研究中在体外条件下研究不同浓度的桉叶油对瘤胃中生产甲烷的抑制作用。试验设计为:不同精粗比的饲粮,分别为70:30和60:40。饲粮干物质中桉叶油的浓度... 详细信息

畜牧业产生的甲烷是引起全球变暖的主要因素。地球气候变暖成为全球重要问题之一。本研究中在体外条件下研究不同浓度的桉叶油对瘤胃中生产甲烷的抑制作用。试验设计为:不同精粗比的饲粮,分别为70:30和60:40。饲粮干物质中桉叶油的浓度分别为0 mL/kg、2 mL/kg、4 mL/kg、6 mL/kg、8 mL/kg和10 mL/kg。试验采用的瘤胃原液从两只健康瘘管绵羊获取,分别在3 h、6 h、9 h、12 h、24 h、36 h、48 h和72 h,检测气压(GP)、甲烷产量(CH4)。发酵(72 h)结束后,检测挥发性脂肪酸(VFA)、氨态氮(NH3)、干物质降解率(DMD)及有机物降解率(OMD)、pH值和原生动物数等。结果表明,不同浓度的桉叶油处理条件下,甲烷产量有所降低(P<0.05)。在精粗比30:70的处理中,2 mL/kg组的甲烷产量较对照组减少32%,10 mL/kg组的甲烷产量较对照组减少38%。在精粗比60:40的处理中,2 mL/kg组的甲烷产量较对照组减少42%,10 mL/kg组的甲烷产量较0 mL/kg组减少46%。在所有精粗比处理中,通过提高桉叶油的浓度,与0 mL/kg组相比,原虫数量显著下降(P<0.05)。NH3浓度较0 mL/kg组下降,在精粗比为60:40组中不显著,在70:30中显著(P<0.05)。在所有精粗比处理中,随着桉叶油浓度的提高,A/P值、DMD和OMD都显著下降(P<0.05)。除了精粗比70:30处理中的10 mL/kg组,其他各组的pH值没有显著差异。综上,2 mL/kg组为效率最高组。该浓度的桉叶油降低甲烷气体为最佳浓度。同时成本也是最低的。

关键词：污染瘤胃桉叶油甲烷反刍动物

Assessment of fibroblast growth factor 19 as a non-invasive serum marker for hepatocellular carcinoma

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World Journal of Hepatology 2022年第3期14卷 623-633页

作者： Ghada abdelrahman mohamed Ehab Hasan Nashaat Hadeer mohamed Fawzy ahmed mohamed ElGhandour Department of Internal Medicine Gastroenterology and Hepatology UnitFaculty of MedicineAin Shams UniversityCairo 11591Egypt

BACKGROUND Fibroblast growth factor 19(FGF-19)is one of the founding members of the endocrine FGF ***,it has been the subject of much interest owing to its role in various physiological processes affecting glucose and lipid metabolism and the regulation of bile acid secretion as well as cell proliferation,differentiation,and ***,FGF-19 secretion in an autocrine style has reportedly contributed to cancer progression in various types of malignancies including hepatocellular carcinoma(HCC).AIM To estimate the serum FGF-19 concentrations in HCC cases and assess its diagnostic performance for the detection of *** We recruited 90 adult participants and divided them into three equal groups:Healthy controls,cirrhosis patients,and HCC *** FGF-19 concentrations were measured using the Human FGF-19 ELISA *** We detected a high statistically significant difference in serum FGF-19 levels among the three *** highest level was observed in the HCC group,followed by the cirrhosis and control groups(236.44±40.94 vs 125.63±31.54 vs 69.60±20.90 pg/mL,respectively,P≤0.001).FGF-19 was positively correlated with alpha fetoprotein(AFP;r=0.383,P=0.003)and international normalised ratio(r=0.357,P=0.005),while it was negatively correlated with albumin(r=-0.500,P≤0.001).For the detection of HCC,receiver operating characteristic curve analysis showed that the best cut-off point of AFP was>8.2 ng/mL with an area under the curve(AUC)of 0.78,sensitivity of 63.33%,specificity of 83.33%,positive predictive value(PPV)of 79.2%,negative predictive value(NPV)of 69.4%,and total accuracy of 78%.However,FGF-19 at a cut-off point>180 pg/mL had an AUC of 0.98,sensitivity of 100%,specificity of 90.0%,PPV of 90.0%,NPV of 100%,and total accuracy of 98%.CONCLUSION FGF-19 represents a possible novel non-invasive marker for *** may improve the prognosis of HCC patients due to its utility in several aspects of HCC detection and management.

关键词： Fibroblast growth factor 19 FGF-19 Fibroblast growth factors Tumour biomarkers Hepatocellular carcinoma Detection Cirrhosis

Schistosomal(bilharzial)polyps:Travel through the colon and beyond

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World Journal of Gastroenterology 2023年第26期29卷 4156-4165页

作者： mohamed H Emara Aya M Mahros abdelrahman M ahmed Rasheda mohamed I Radwan Besher mohamed Osama Abdelrazik Mostafa Elazab Hassan Elbatae Department of Hepatology Gastroenterology and Infectious DiseasesKafrelsheikh UniversityKafr-Elshikh 33516Egypt Department of Internal Medicine Gastroenterology UnitSecurity Forces HospitalRyiadh 11481Saudi Arabia Department of Tropical Medicine Zagazig UniversityZagazig 44519Egypt Department of Gastroenterology Surrey and Sussex Hospitals NHS TrustSurrey RH15RHUnited Kingdom Department of Hepato-Gastroenterology and Infectious Diseases Al-Azhar UniversityCairo 11651Egypt

Schistosomiasis(bilharziasis)is a major neglected tropical *** is endemic in many tropical and subtropical *** polyps(***)are not uncommon presentation of this *** the colon is the most commonly affected organ,many other organs are *** are associated with a variable range of morbidity independent of the Schistosomal *** are frequently described in endemic areas and increasingly reported in non-endemic areas mainly among immigrants and visitors to the endemic *** review aimed to increase awareness of practitioners,especially gastroenterologists,for this peculiar type of polyps caused by this neglected infection hence improving patient ***-based search of different databases was conducted for the literature focusing the development of *** in the colon and other organs with analysis of the clinical manifestations,diagnosis and *** following key words were used in the search,“Schistosomiasis”OR“Bilharziasis”AND“Polyps”OR“Polyp”AND“Colon”OR“Small intestine”OR“Duodenum”OR“Stomach”OR“Esophagus”OR”Gallbladder”OR”Pharynx”OR“Larynx”OR“Trachea”OR”Urinary bladder”OR“Ureter”OR“Renal Pelvis”OR“Urethra”.All publication types including case reports,case series,original research,and review articles were retrieved and *** are not infrequent presentation of acute or chronic Schistosomal *** are described in many organs including the bowel,genitourinary tract,skin,gallbladder and the *** of *** is variable and depends on the site,number as well as the polyp *** relationship of *** to malignant transformation is a matter of *** of *** is sometimes the only manifestation of *** polyps can be treated medically with praziquantel,while large accessible polyps are amendable for endoscopic excision through different polyp resection ***,huge,complicated,non-accessible and sus

关键词： Schistosomiasis Bilharziasis Schistosomal polyps Colon Praziquantel

Performance Analysis with Channel Estimation and Adaptive Equalization in Slow Rayleigh Fading Channel for8-QPSK and256-QAM

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Performance Analysis with Channel Estimation and Adaptive Eq...

作者： ahmed mohamed Ali abdelrahman 湖南大学

学位级别：硕士

在过去的几十年里,因为在对抗多径衰落信道中支持高数据速率和有效性,人们已经对多载波系统进行广泛的研究。多载波调制(MCM)是将数据流分成几个并行的比特流,每个比特率要低得多,并通过使用这些比特流传输数据。多载波调制(MCM)代表目... 详细信息

在过去的几十年里,因为在对抗多径衰落信道中支持高数据速率和有效性,人们已经对多载波系统进行广泛的研究。多载波调制(MCM)是将数据流分成几个并行的比特流,每个比特率要低得多,并通过使用这些比特流传输数据。多载波调制(MCM)代表目前和未来的高速数字通信。许多新的有线和无线通信应用要求高数据速率和大的带宽。MCM通过正交频分复用(OFDM)的形式应用于在一些如数字音频广播(DAB),数字视频广播(DVB)和无线局域网(WLAN)的无线通信系统中。正交频分复用(OFDM)引入了有限的物理信道带宽内分配更多的交通信道的概念。因此,可用带宽分成几个同时传输的窄带通道。在频分复用,保护带提供个人之间的通道,分隔不同的渠道,能够使用特殊的频段检测通道。在相邻信道的OFDM中不同的频率划分重叠类似于相邻信道干扰,但子载波之间保持正交关系。通过采用OFDM,这是有可能实现对多径信道的高的频率利用率和鲁棒性。在OFDM系统中,调制技术,如BPSK(二进制相移键控)和多级正交调幅(M-QAM)映射到信号星座符号固定数量的信息比特。每个信号的星座符号代表在二维的基带信号空间的一个点。在这篇论文中,我们将测试三种不同的通道(AWGN信道,平坦衰落信道,频率选择性信道)下,数据和图像通过256-QAM和8-QPSK调制接收星座和误码率(BER)。为了比较模拟信道衰落和接收器的设计,我们首先需要选择的相应的标准。目前有很多的根据信道衰落和需要估计标准,如OFDM, CDMA RAKE接收机,MIMO技术等。在本文中,我们选择OFDM标准。我们首先使用MATLAB建立一个无线通信模拟器,包括灰度编码,调制,三通道模式,信道估计,自适应均衡和解调。在我们的模拟中,我们测试不同的信道模式下的256-QAM和8-QPSK的调制星座图和误码率(BER)。在此模型中,我们使用的基于导频信道估计。这是因为导频信息是由接收器使用以便更好地估计在传播符号的频率衰落下有者更高数据接收率。在我们的模型,试验数据的长度是数据总长度的8%,并插入到每个相干时间源数据的头节点。我们还可以使用最小均方(LMS),自适应均衡,以帮助消除无线通道的影响以方便解调。对于图像而言,我们比较在不同的渠道收到的图像和原始图像。在瑞利慢平坦衰落信道,我们比较接收和调整后的图像。另一方面,在瑞利慢衰落信道频率选择性,我们测试在两个不同的模式(判决引导和训练)下接受到的图像。在我们的模型,测试图像文件给我们不同的信道比较下直观的印象。最后,我们给出详细结果和分析在慢瑞利衰落信道下信道估计和自适应均衡的性能改善。仿真结果表明,不像8QPSK在随机数据下平坦衰落信道仿真结果,256-QAM的误码率性能几乎与理论误码率相同。此外,使用256-QAM编码,在频率选择性衰落信道的中决策指示比培训模式的误码率更好,大多数情况下接近理论值。此外,通过比较图像文件,我们可以得到,在频率选择性衰落信道中,决策指挥模式下的256-QAM几乎接近原始图像的质量。这意味着,在256-QAM,均衡的图像不受任何噪音影响。这是因为256-QAM可以发送8位符号这是非常有效率,不同于8-QPSK,受到一些随机噪声导致图像的重叠。

关键词：信道估计 AWGN 慢衰落平坦衰落和频率选择性衰落