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Salivary C-reactive protein and mean platelet volume as possible diagnostic markers for late-onset neonatal pneumonia

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World Journal of Clinical Pediatrics 2024年第1期13卷 41-51页

作者： Wafaa Ahmed Metwali abdelrahman mohamed Elmashad Sahar Mohey Eldin Hazzaa Mohammed Al-Beltagi mohamed Basiony Hamza Department of Pediatric Faculty of MedicineTanta UniversityTanta 31511AlgahrbiaEgypt Department of Clinical Pathology Faculty of MedicineTanta UniversityTanta 31511AlgahrbiaEgypt Department of Pediatric University Medical CenterDr.Suliaman Al Habib Medical GroupManama 26671ManamaBahrain Department of Pediatric University Medical CenterKing Abdulla Medical CityArabian Gulf UniversityManama 26671ManamaBahrain

BACKGROUND Neonatal sepsis,a formidable threat to newborns,is a leading cause of neonatal mortality,with late-onset sepsis manifesting after 72 hours post-birth being particularly ***,a prevalent sepsis presentation,poses a significant risk,especially during the neonatal phase when lung defenses are *** diagnosis of pneumonia is imperative for timely and effective ***,a minimally invasive diagnostic medium,holds great promise for evaluating infections,especially in *** To investigate the potential of serum C-reactive protein(CRP),salivary CRP(sCRP),and mean platelet volume(MPV)as diagnostic markers for late-onset neonatal pneumonia(LONP).METHODS Eighty full-term neonates were systematically examined,considering anthropometric measurements,clinical manifestations,radiology findings,and essential biomarkers,including serum CRP,sCRP,and *** The study reveals noteworthy distinctions in serum CRP levels,MPV,and the serum CRP/MPV ratio between neonates with LONP and healthy *** exhibited a robust discriminatory ability[area under the curve(AUC)=0.87]with high sensitivity and specificity at a cutoff value of>*** between serum CRP,sCRP,and MPV were also ***,sCRP demonstrated excellent predictive value for serum CRP levels(AUC=0.89),underscoring its potential as a diagnostic *** This study underscores the diagnostic promise of salivary and serum biomarkers,specifically MPV and CRP,in identifying and predicting LONP among *** findings advocate for further research to validate their clinical utility in larger neonatal cohorts.

关键词： Neonatal sepsis Late-onset pneumonia Salivary C-reactive protein Mean platelet volume Diagnostic markers Newborn infections

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大学生创业企业中变革型领导行为对其企业绩效的影响研究

大学生创业企业中变革型领导行为对其企业绩效的影响研究

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作者： abdelrahman NASR abdelrahman mohamed 华东师范大学

学位级别：硕士

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Sero-Prevalence and Risk factors of Contagious Bovine Pleuropneumonia (CBPP) in Afgoye District Lower Shabelle Region, Somalia

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Open Journal of Veterinary Medicine 2024年第2期14卷 11-20页

作者： Ahmed mohamed Ahmed Sumaya Hassan Ali Abdisalam mohamed Ali Abdirazack Saleban Osman Binti Abubakar mohamed Abdifatah Mohamud Ibar Shafii Abdullahi mohamed mohamed abdelrahman mohamed Ahmed Ali Omar Zakaria Ibrahim Issack College of Veterinary Medicine Abrar University Mogadishu Somalia Faculty of Veterinary Medicine and Animal Husbandry Somali National University Mogadishu Somalia Faculty of Veterinary Science Benadir University Mogadishu Somalia

Contagious bovine Pleuropneumonia (CBPP) is an infectious and highly contagious respiratory disease of cattle and water buffalo, caused by the Mycoplasma mycoides subspecies mycoides. It induces significant economic losses and leads to a severe livestock production problem, negatively influencing people’s livelihoods of affected countries. In Somalia, there is no updated data on the prevalence and distribution of the disease. Hence, a descriptive cross-sectional study was conducted from September 2022 to June 2023 in different villages under the Afgoye District of lower Shabelle region, Somalia. The main purpose of this study is to assess the sero-prevalence and identify the associated risk factors for the occurrence of the disease. In this study, villages, age, sex, breed, and body condition were considered as risk factors. A total of 90 blood samples were collected and tested in the laboratory using the Anti-CBPP Elisa kit test. Out of 90 serum samples from herd cattle, 32 were positive, resulting in an overall prevalence of 35.5%. In addition, we found a statistically significant variation between the prevalence of the disease and factors such as sex, age, body condition and breeds. In summary, the overall prevalence of Contagious bovine pleuropneumonia in this study area is worth to be considered because there is a low quality of health care and less awareness of the Contagious bovine Pleuropneumonia effects on herds, which warrants the official authorities to act and follow appropriate preventive and control measures to reduce the incidence of the disease and generate appropriate controlling and prevention measures in all regions of Somalia.

关键词： Contagious Bovine Pleuropneumonia Sero-Prevalence Cattle Somalia Mycoplasma Cross Sectional Study

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Techno-economic analysis to develop the first wind farm in the Egyptian western desert at Elkharga Oasis

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Clean Energy 2022年第1期6卷 211-225页

作者： mohamed A.abdelrahman Radwan H.Abdel-Hamid Maged Ahmed Abo Adma mohamed Daowd Electrical Power and Machines Department Faculty of EngineeringHelwan UniversityCairoEgypt

During the past few years,Egypt has increased the share of electricity generation from renewable energy sources to achieve the renewable-energy *** Egyptian Ministry of Electricity and Renewable Energy has set an ambitious target to increase the share of renewable energy among the total energy mix to be 20%by 2022 and 42%by *** target will be achieved using several approved policies such as feed-in tariffs,build-own-operate and independent power producers under a merchant *** paper presents a full analysis of wind-potential characteristics at Elkharga Oasis in Egypt based on an actual wind-measurement campaign taken by a met mast at two height levels of 10 and 25 m,*** measurements show an average annual wind speed of 5.72 m/s at 10-m height and 6.53 m/s at>25-m *** estimated wind speed,however,is 8.38 m/s at 120 m,which is technically convenient to generate electricity from wind *** this paper,the wind potential in the area is assessed using the statistical method of the Weibull probability density *** different methods to estimate the Weibull distribution parameters are presented and the relevant accuracy is verified based on the root mean square error.A techno-economic assessment and selection of the optimal wind-turbine size with ideal micro-sitings are performed using the software package *** cases of study for three typical wind-turbine models with various rotor diameters,power capacity,layout configuration and annual yield are assessed at the *** selection of the most convenient wind turbine is determined based on the IEC 61400 standard criteria and the turbine that produces the lowest levelized cost of electricity.

关键词： wind energy wind-resource assessment Weibull distribution windPRO levelized cost of electricity

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HDR Image Reconstruction from a Single LDR Image Using Deep CNN

HDR Image Reconstruction from a Single LDR Image Using Deep ...

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作者： mohamed abdelrahman Ahmed Dafaallah 山东大学

学位级别：硕士

高动态范围（HDR）成像是图像处理和计算机图形方面的快速增长领域。这是一种可以代表各种现实世界亮度的摄影技术。相比之下,传统成像也称为低动态范围（LDR）成像不能代表真实世界的强度和颜色,因为大多数数码相机都可以在自然场景中... 详细信息

高动态范围（HDR）成像是图像处理和计算机图形方面的快速增长领域。这是一种可以代表各种现实世界亮度的摄影技术。相比之下,传统成像也称为低动态范围（LDR）成像不能代表真实世界的强度和颜色,因为大多数数码相机都可以在自然场景中捕获有限的光强度范围。HDR成像克服了这种限制,允许捕获和传递可以与人类视觉系统的动态范围相匹配的信息。此HDR信息可用于各种应用程序,例如音调映射,基于图像的照明,HDR显示器,计算机视觉和其他后处理操作。HDR成像已经有了很多开发,但是尽管如此,就内容而言,LDR成像仍然是当今的标准。要在不同的HDR应用程序中使用此内容,需要将LDR内容转换为HDR,并将由于饱和或量化而丢失的信息需要恢复。本文工作的目的是开发深神网络,目的是从单个暴露LDR图像中重建HDR图像。我们利用卷积神经网络能力来克服先前作品的局限性,并处理重建HDR内容（例如暴露面积过度,暴露面积不足的区域,量化和线性化）时遇到的问题。在这项工作中,我们提出了两个用于HDR图像重建的新型CNN。使用深度学习的最新进展,在大型HDR图像数据集上对网络进行了培训。第一种方法在卷积自动编码网络上使用深度监督技术。除了输出层的总体损耗函数外,深度监督还增加了每个隐藏层的伴侣损失功能。这有助于网络轻松恢复较低分辨率的结构,并以更高分辨率恢复纹理。第二种方法采用了卷积自动编码器,该自动编码器使用剩余学习技术来加速培训,注意机制以增强有用的功能和上下文注意模块,以帮助恢复在暴露区域中丢失的信息。公共HDR数据集的广泛定量和定性实验表明,与现有方法相比,我们提出的方法有效地重建视觉上令人愉悦的HDR图像并显示出更好的性能的能力。

关键词：深度学习卷积神经网络计算摄影 HDR成像单幅图像HDR重建

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Assessment of fibroblast growth factor 19 as a non-invasive serum marker for hepatocellular carcinoma

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World Journal of Hepatology 2022年第3期14卷 623-633页

作者： Ghada abdelrahman mohamed Ehab Hasan Nashaat Hadeer mohamed Fawzy Ahmed mohamed ElGhandour Department of Internal Medicine Gastroenterology and Hepatology UnitFaculty of MedicineAin Shams UniversityCairo 11591Egypt

BACKGROUND Fibroblast growth factor 19(FGF-19)is one of the founding members of the endocrine FGF ***,it has been the subject of much interest owing to its role in various physiological processes affecting glucose and lipid metabolism and the regulation of bile acid secretion as well as cell proliferation,differentiation,and ***,FGF-19 secretion in an autocrine style has reportedly contributed to cancer progression in various types of malignancies including hepatocellular carcinoma(HCC).AIM To estimate the serum FGF-19 concentrations in HCC cases and assess its diagnostic performance for the detection of *** We recruited 90 adult participants and divided them into three equal groups:Healthy controls,cirrhosis patients,and HCC *** FGF-19 concentrations were measured using the Human FGF-19 ELISA *** We detected a high statistically significant difference in serum FGF-19 levels among the three *** highest level was observed in the HCC group,followed by the cirrhosis and control groups(236.44±40.94 vs 125.63±31.54 vs 69.60±20.90 pg/mL,respectively,P≤0.001).FGF-19 was positively correlated with alpha fetoprotein(AFP;r=0.383,P=0.003)and international normalised ratio(r=0.357,P=0.005),while it was negatively correlated with albumin(r=-0.500,P≤0.001).For the detection of HCC,receiver operating characteristic curve analysis showed that the best cut-off point of AFP was>8.2 ng/mL with an area under the curve(AUC)of 0.78,sensitivity of 63.33%,specificity of 83.33%,positive predictive value(PPV)of 79.2%,negative predictive value(NPV)of 69.4%,and total accuracy of 78%.However,FGF-19 at a cut-off point>180 pg/mL had an AUC of 0.98,sensitivity of 100%,specificity of 90.0%,PPV of 90.0%,NPV of 100%,and total accuracy of 98%.CONCLUSION FGF-19 represents a possible novel non-invasive marker for *** may improve the prognosis of HCC patients due to its utility in several aspects of HCC detection and management.

关键词： Fibroblast growth factor 19 FGF-19 Fibroblast growth factors Tumour biomarkers Hepatocellular carcinoma Detection Cirrhosis

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The Utilization of Eucalyptus Oil for Reducing Methane Production in Ruminants under in Vitro Conditions

The Utilization of Eucalyptus Oil for Reducing Methane Produ...

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作者： Safwat mohamed abdelrahman Ahmed Attia 吉林农业大学

学位级别：硕士

畜牧业产生的甲烷是引起全球变暖的主要因素。地球气候变暖成为全球重要问题之一。本研究中在体外条件下研究不同浓度的桉叶油对瘤胃中生产甲烷的抑制作用。试验设计为:不同精粗比的饲粮,分别为70:30和60:40。饲粮干物质中桉叶油的浓度... 详细信息

畜牧业产生的甲烷是引起全球变暖的主要因素。地球气候变暖成为全球重要问题之一。本研究中在体外条件下研究不同浓度的桉叶油对瘤胃中生产甲烷的抑制作用。试验设计为:不同精粗比的饲粮,分别为70:30和60:40。饲粮干物质中桉叶油的浓度分别为0 mL/kg、2 mL/kg、4 mL/kg、6 mL/kg、8 mL/kg和10 mL/kg。试验采用的瘤胃原液从两只健康瘘管绵羊获取,分别在3 h、6 h、9 h、12 h、24 h、36 h、48 h和72 h,检测气压(GP)、甲烷产量(CH4)。发酵(72 h)结束后,检测挥发性脂肪酸(VFA)、氨态氮(NH3)、干物质降解率(DMD)及有机物降解率(OMD)、pH值和原生动物数等。结果表明,不同浓度的桉叶油处理条件下,甲烷产量有所降低(P<0.05)。在精粗比30:70的处理中,2 mL/kg组的甲烷产量较对照组减少32%,10 mL/kg组的甲烷产量较对照组减少38%。在精粗比60:40的处理中,2 mL/kg组的甲烷产量较对照组减少42%,10 mL/kg组的甲烷产量较0 mL/kg组减少46%。在所有精粗比处理中,通过提高桉叶油的浓度,与0 mL/kg组相比,原虫数量显著下降(P<0.05)。NH3浓度较0 mL/kg组下降,在精粗比为60:40组中不显著,在70:30中显著(P<0.05)。在所有精粗比处理中,随着桉叶油浓度的提高,A/P值、DMD和OMD都显著下降(P<0.05)。除了精粗比70:30处理中的10 mL/kg组,其他各组的pH值没有显著差异。综上,2 mL/kg组为效率最高组。该浓度的桉叶油降低甲烷气体为最佳浓度。同时成本也是最低的。

关键词：污染瘤胃桉叶油甲烷反刍动物

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Validated stability indicating methods for determination of nitazoxanide in presence of its degradation products

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Journal of Pharmaceutical Analysis 2012年第2期2卷 105-116页

作者： Nouruddin W.Ali Samah Sayed Abbas Hala El-Sayed Zaazaa Maha mohamed abdelrahman mohamed Abdelkawy Analytical Chemistry Department Faculty of PharmacyBeni-Suef UniversityHussin El-Shafey StreetBeni-Suef CityEgypt Analytical Chemistry Department Faculty of PharmacyCairo UniversityKasr El-Aini Street11562CairoEgypt

Three sensitive,selective and reproducible stability-indicating methods are presented for determination of nitazoxanide (NTZ),a new anti-protozoal drug,in presence of its degradation *** A utilizes the first derivative of ratio spectra spectrophotometry by measurement of the amplitude at 364.4 nm using one of the degradation products as a *** B is a chemometric-assisted spectrophotometry,where principal component regression (PCR) and partial least squares (PLS) were *** two approaches were successfully applied to quantify NTZ in presence of degradation products using the information included in the absorption spectra in the range 260-360 *** C is based on the separation of NTZ from its degradation products followed by densitometric measurement of the bands at 254 *** separation was carried out on silica gel 60F 254,using chloroform-methanol-ammonia solution-glacial acetic acid (95:5:1:1 by volume,pH=5.80) as a developing *** methods are suitable as stability-indicating methods for the determination of NTZ in presence of its degradation products either in bulk powder or in pharmaceutical *** analysis of the results has been carried out revealing high accuracy and good precision.

关键词： Nitazoxanide Degradation Derivative spectrophotometry Chemometrics TLC-densitometry Stability-indicating methods

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Engineering Broad-Spectrum Resistance to Bacterial Blight by CRISPR/Cas9-Mediated Precise Homology Directed Repair in Rice

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Molecular Plant 2021年第8期14卷 1215-1218页

作者： Zheng Wei mohamed abdelrahman Ying Gao Zhiyuan Ji Rukmini Mishra Hongda Sun Yi Sui Chuanyin Wu Chunlian Wang Kaijun Zhao National Key Facility for-Crop Gene Resources and Genetic Improvement Institute of Crop SciencesChinese Academy of Agricultural SciencesBeijingChina Rice Research and Training Center Field Crops Research InstituteAgricultural Research CenterKafrelsheikhEgypt

Dear Editor,Rice(Oryza sativa)is one of the most important food crops as well as a model plant for basic *** bacterial blight(BB)caused by Xanthomonas oryzae ***(Xoo)is a devastating bacterial disease worldwide(Mew et al.,1993),affecting millions of hectares of rice annually,with an estimated crop loss of as high as 75%.Upon invasion of rice cells,Xoo secretes transcription activator-like effectors(TALEs)to activate the host Sugars Will Eventually be Exported Transporters(SWEET)genes to obtain nutrition for bacterial growth,because the induced SWEET transports more sugars to where the bacteria reside(Boch and Bonas,2010).

关键词： sativa CRISPR/Cas9 blight

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Combination of Diclofenac Potassium and Propolis in the Therapy of Oral Aphthosis: A Randomized, Clinical, Double-Blind, Placebo-Controlled Study

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Open Journal of Stomatology 2023年第11期13卷 422-432页

作者： mohamed Ismail Assadawy Hisham mohamed Abozaid Abdelraheem Ramadan Elgendy abdelrahman mohamed Galal Department of Oral Medicine Periodontology Oral Diagnosis and Oral Radiology Faculty of Dental Medicine (Boys-Cairo) Al-Azhar University Cairo Egypt Department of Oral Biology Faculty of Dental Medicine (Boys-Cairo) Al-Azhar University Cairo Egypt

Background: Oral aphthosis has a negative impact on oral health. This study aimed to assess the effectiveness of gel formulation including diclofenac and propolis in the treatment of oral ulcers. Methods: Participants included 100 normal individuals with aphthous, excluding those having allergies to any ingredient in the diclofenac formulation. Patients were randomly assigned into two groups: one group received treatment with a combination of diclofenac potassium 3% (10 mg/g, 60 g) and propolis 5% gel (Group II), and the other group received a placebo (Group 1). The patient was evaluated using standard digital photographs and chronic oral mucosal questionnaires on days 1, 3, 5, and 7 after healing. Utilizing the Mann-Whitney U test, the two groups were compared. Each group’s changes were examined using Friedman’s test. Results: There was a statistically dramatic change over time in Group II. After one day, the median total score dropped statistically significantly, and from one to three days with effect size (d) 2.485, Group II demonstrated 48% complete healing and 52% partial healing, while Group I demonstrated 4% partial healing and 96% no change. Effect size (V): 0.995. Conclusions: The combination of diclofenac and propolis provided instant relief and an affordable new regimen for treating oral aphthosis.

关键词： Ulcer Biology Healing Inflammation Corticosteroids Propolis Diclofenac Potassium Oral Aphthosis

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