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Fosfomycin Therapy for Non-Complicated Lower Urinary Tract Infections during Pregnancy: Tanta University Experience

Open Journal of Obstetrics and Gynecology 2017年第5期7卷 532-544页

作者： Ayman Shehata Dawood Abdelghaffar Said Dawood Salah Abdelmonsef Nagla mohamed abdelatti el-bakary Department of Obstetrics and Gynecology Tanta University Tanta Egypt Department of Urology Tanta University Tanta Egypt

Objectives: To evaluate the efficacy, compliance, safety and economic cost for Fosfomycin trometamol and Nitofurantoin in uncomplicated lower urinary tract infections during pregnancy. Background: Nitofurantoin and Fosfomycin trometamol are recommended as the first-line agents for treatment of urinary tract infections (UTIs) in the latest guidelines endorsed by the Infectious Diseases Society of America (IDSA) and the European Society for Clinical Microbiology and Infectious Diseases (ESCMID). Fosfomycin is bactericidal and inhibits bacterial cell wall biogenesis and reduces bacterial adherence to uroepithelial cells. Fosfomycin has broad antibacterial activity against both Gram-positive and Gram-negative pathogens, as Escherichia coli, Escherichia faecalis, and various Gram-negatives like Citrobacter and Proteus. Both Nitofurantoin and Fosfomycin are category B in pregnancy. Patients and Methods: This study was conducted at Tanta University Hospitals in the period from June, 1, 2015 to January, 1, 2017. Patients were recruited from outpatient clinics of Obstetrics and Gynecology and Urology Departments presenting with asymptomatic bacteruria or cystitis. Patients were allocated randomly into 2 groups: group I (n = 50 cases) received Fosfomycin therapy and group II (n = 50 cases) received Nitofurantoin therapy (n = 50 cases). After treatment, evaluation of patient symptoms, organism count, patient compliance and cost of treatment were done. Results: The enrolled patients were suffering from lower urinary tract infections;asymptomatic bacteruria (17 cases) or cystitis (83 cases). Ten patients were excluded. The demographic data of included patients were not significant for both groups. Complete relief (100%) of symptoms 5 days after start of treatment was noticed in Fosfomycin group while improvement of symptoms after 5 day-treatment was noticed in 86.49% in Nitofurantoin group (p-value = 0.030). The side effects were recorded in 7 cases (18.42%) in Fosfomycin group

关键词： Fosfomycin Nitofurantoin Pregnancy UTIs Asymptomatic Bacteuria Cystitis

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Comparison between seismic analysis of twisting and regular 52-story towers considering soil-structure interaction

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Earthquake Engineering and Engineering Vibration 2024年第3期23卷 663-675页

作者： mohamed Naguib Abouelsaad Mohammed Shaaban Salah el Bagalaty mohamed E.el Madawy Structural Engineering Department Faculty of EngineeringMansura UniversityMansoura 35511Egypt Faculty of Engineering Delta University for Science and TechnologyGamasa 35712Egypt

A dynamic analysis of both twisting and regular towers is carried out to determine the results of considering soil-structure interaction(SSI)on high-rise *** addition,the difference between the seismic performance of using twisting towers over regular ones is *** twisting tower is a simulation of the Evolution Tower(Moscow).The towers’skeletons consist of RC elements and rest on a reinforced concrete piled-raft *** soil model is considered as multi-layered with the same soil properties as the zone chosen for the analysis(New Mansoura City,Egypt).The only difference between both towers is their shape in *** whole system is modelled and analyzed in a single step as one full 3D model,which is known as the direct approach in *** analyses are carried out using finite-element software(Midas GTS NX).Dynamic output responses due to three records of seismic loads are proposed and presented in some *** on the results,it is concluded that SSI has a considerable effect on the dynamic response of tall buildings mainly because of the foundation flexibility,as it leads to lengthening the vibration period,increasing the story drift and the base shear for both cases.

关键词： soil-structure interaction seismic analysis twisting towers base shear story drift finite element method Midas GTS NX

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A review on the multi-scaled structures and mechanical/thermal properties of tool steels fabricated by laser powder bed fusion additive manufacturing

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International Journal of Minerals,Metallurgy and Materials 2024年第5期31卷 1048-1071页

作者： Huajing Zong Nan Kang Zehao Qin mohamed el Mansori Arts et Metiers Institute of Technology MSMPHESAM UniversitéChâlons-en-Champagne F-51006France Texas A&M Engineering Experiment Station Institute for Manufacturing SystemsCollege Station TX77843USA

The laser powder bed fusion(LPBF) process can integrally form geometrically complex and high-performance metallic parts that have attracted much interest,especially in the molds *** appearance of the LPBF makes it possible to design and produce complex conformal cooling channel systems in ***,LPBF-processed tool steels have attracted more and more *** complex thermal history in the LPBF process makes the microstructural characteristics and properties different from those of conventional manufactured tool *** paper provides an overview of LPBF-processed tool steels by describing the physical phenomena,the microstructural characteristics,and the mechanical/thermal properties,including tensile properties,wear resistance,and thermal *** microstructural characteristics are presented through a multiscale perspective,ranging from densification,meso-structure,microstructure,substructure in grains,to ***,a summary of tool steels and their challenges and outlooks are introduced.

关键词： additive manufacturing laser powder bed fusion tool steel multi-scaled structure mechanical properties thermal properties

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Genetic Variability and Phenotypic Correlations Study among Grain Quality Traits and Mineral elements Concentrations in Colored and Non-Colored Rice (Oryza sativa L.)

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Phyton-International Journal of Experimental Botany 2024年第7期93卷 1733-1748页

作者： Adel A.Rezk mohamed M.el-Malky Heba I.mohamed Hossam S.el-Beltagi Agricultural Biotechnology Department College of Agricultural and Food ScienceKing Faisal UniversityAl-Ahsa31982Saudi Arabia Plant Pathology Research Institute Agriculture Research CenterGiza12619Egypt Rice Research and Training Center Field Crop Research InstituteAgriculture Research Center33717Egypt Biological and Geological Sciences Department Faculty of EducationAin Shams UniversityCairo11511Egypt Biochemistry Department Faculty of AgricultureCairo UniversityGiza12613Egypt

Twenty-four rice genotypes were examined to assess genetic variability,heritability,and correlations for seven-grain quality traits,eight nutritional elements,and *** revealed signiﬁcant differences for the quality traits *** every trait under study,the phenotypic coefﬁcient of variation was higher than the correspon-dence genotypic coefﬁcient of *** in a broad sense varied from 29.75%for grain length to 98.31%for the elongation *** percentage recovery had a highly signiﬁcant positive correlation with milling and head rice ***,milling percentage had a highly positive correlation with head rice *** amylose percentage,all the genotypes belonged to low amylose except the Hassawi-1 variety,which had intermediate amylose *** nutrition contents of magnesium(Mg),sodium(Na),potas-sium(K),calcium(Ca),copper(Cu),manganese(Mn),zinc(Zn),iron(Fe),or protein percentage gave different variations for 24 rice genotypes under all the nutritional *** the 24 genotypes,ten rice genotypes–HighNutrient-1,HighNutrient-2,HighNutrient-9,HighNutrient-8,HighNutrient-3,Hassawi-2,HighNutrient-7,HighNutrient-6,Hassawi-1,and HighNutrient-4–had the highest heist value for all nutritional and protein con-tents,and could be used as a donor to improving new *** was a positive and signiﬁcant correlation between magnesium Mg,K,Zn and ***,K had a positive correlation with zinc Zn,Fe,and protein *** analysis was divided into two groups:theﬁrst group included all genotypes rich in nutri-ents,while the remaining genotypes with low nutritional content were included in the second group.

关键词： Amylose cluster analysis genotypes grain quality mineral nutrition rice

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Mafic and felsic magmatism in the Wadi Kalalat area, South Eastern Desert, Egypt: mineralogy, geochemistry and geodynamic evolution during the Neoproterozoic in the Nubian Shield

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Acta Geochimica 2024年第1期43卷 150-173页

作者： Adel A.Surour Ahmed A.Madani mohamed A.el-Sobky Faculty of Science Galala UniversityNew Galala CitySuez 43511Egypt Department of Geology Faculty of ScienceCairo UniversityGiza 12613Egypt Egyptian Mineral Resources Authority P.O.Box 11517AbbasiyaCairoEgypt

In the south Eastern Desert of Egypt,two contrasting types of magmatism(mafic and felsic) are recorded in the Wadi Kalalat area,and form the Gabal el Motaghiarat and Gabal Batuga intrusions,*** two intrusions post-dates ophiolitic and arc associations represented by serpentinite and metagabbro-diorite,*** mafic intrusion has a basal ultramafic member represented by fresh peridotite,which is followed upward by olivine gabbro and anorthositic or *** mafic intrusion pertains to the Alaskan-type mafic-ultramafic intrusions in the Arabian-Nubian Shield(ANS)being of tholeiitic nature and emplaced in a typical arc *** the other hand,the Gabal Batuga intrusion comprises three varieties of fresh A-type granites of high K-calc alkaline nature,which is peraluminous and garnetbearing in parts.A narrow thermal aureole in the olivine gabbro of the mafic intrusion was developed due to the intrusion of the Batuga *** results in the development of a hornfelsic melagabbro variety in which the composition changed from tholeiitic to a calc-alkaline composition due to the addition of S_(i)O_(2),Al_(2)O_(3),alkalis,lithosphile elements(LILEs) such as Rb(70 ppm) and Y(28 ppm) from the felsic *** the thermal aureole,Rb amounts 2-8 ppm and Y lies in the range elieved that the Gabal Batuga felsic intrusion started to emplace during the waning stage of an arc system,with transition from the pre-collisional(i.e.,arc setting) to post-collisional and within plate *** from which the Gabal Batuga granites were fractionated is high-K calc-alkaline giving rise to a typical post-collisional A-type granite(A_(2)-subtype) indicating an origin from an underplating crustal ***,it is stressed here that the younger granites in the ANS are not exclusively post-collisional and within-plate but most likely they started to develop before closure of the arc *** possible source(s) of mafic magmas

关键词： Wadi Kalalat Gabal el Motaghairat mafic intrusion Gabal Batuga felsic intrusion Arc setting Post-collision Within-plate

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Hepatitis B virus as a risk factor for hepatocellular carcinoma: There is still much work to do

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Liver Research 2024年第2期8卷 83-90页

作者： Walaa Abdelhamed mohamed el-Kassas Endemic Medicine Department Sohag University Sohag Egypt Endemic Medicine Department Faculty of Medicine Helwan University Cairo Egypt Liver Disease Research Center College of Medicine King Saud University Riyadh Saudi Arabia

Hepatitis B virus (HBV) infection is a significant health problem that can result in progression to liver cirrhosis, decompensation, and the development of hepatocellular carcinoma (HCC). On a country level, the prevalence of chronic HBV infection varies between 0.1% and 35.0%, depending on the locality and the population being investigated. One-third of all liver cancer fatalities worldwide are attributable to HBV. The adoption of standard birth-dose immunization exerted the most significant impact on the decline of HBV prevalence. HCC incidence ranges from 0.01% to 1.40% in noncirrhotic patients and from 0.9% to 5.4% annually, in the settings of liver cirrhosis. Although antiviral therapy significantly reduces the risk of developing HBV-related HCC, studies have demonstrated that the risk persists, and that HCC screening is still essential. This review discusses the complex relationship between HBV infection and HCC, recent epidemiological data, different aspects of clinical disease characteristics, and the impact of antiviral therapy in this context.

关键词： Hepatitis B virus (HBV) Hepatocellular carcinoma (HCC) HBV vaccine Carcinogenesis Antiviral therapy

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Evaluation of urea breath test as a diagnostic tool for Helicobacter pylori infection in adult dyspeptic patients

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World Journal of Gastroenterology 2024年第17期30卷 2302-2307页

作者： Zeinab Nabil Ahmed Said Asmaa mohamed el-Nasser Department of Medical Microbiology&Immunology Faculty of Medicine for Girls Al-Azhar UniversityNasr City 11754CairoEgypt

In this editorial,we discuss the article in the World Journal of *** article conducts a meta-analysis of the diagnostic accuracy of the urea breath test(UBT),a non-invasive method for detecting Helicobacter pylori(***)infection in *** is based on radionuclide-labeled *** methods,both invasive and non-invasive,are available for diagnosing *** infection,inclu-ding endoscopy with biopsy,serology for immunoglobulin titers,stool antigen analysis,and *** guidelines recommend UBTs as the primary choice for diagnosing *** infection and for reexamining after eradication *** is used to be the first choice non-invasive test due to their high accuracy,specificity,rapid results,and ***,its performance remains unaffected by the distribution of *** in the stomach,allowing a high flow of patients to be *** its widespread use,the performance characteristics of UBT have been inconsistently described and remain incompletely *** are two UBTs available with Food and Drug Administration approval:The 13C and 14C *** tests are affordable and can provide real-time *** may prefer the 13C test because it is non-radioactive,compared to 14C which uses a radioactive isotope,especially in young children and pregnant *** there was heterogeneity among the studies regarding the diagnostic accuracy of both UBTs,13C-UBT consistently outperforms the *** makes the 13C-UBT the preferred diagnostic ***,the provided findings of the meta-analysis emphasize the significance of precise considerations when choosing urea dosage,assessment timing,and measurement techniques for both the 13C-UBT and 14C-UBT,to enhance diagnostic precision.

关键词： Helicobacter pylori Urea breath test Diagnosis Diagnostic test accuracy Meta-analysis

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Dysprosium oxide,alumina,and graphene oxide reinforced polycaprolactone thin films:Thermal stability,morphology,and cell viability

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Journal of Rare Earths 2024年第7期42卷 1337-1343,I0005页

作者： mohamed Tharwat elabbasy mohamed R.Atteya Mai A.Samak Mousa Abdelrahman Tahani AlMahmoud M.A.el-Morsy A.A.Menazea M.F.H.Abd el-Kader Department of Public Health College of Public Health and Health InformaticsUniversity of Ha'ilHa'il2440Saudi Arabia Food Control Department Faculty of Veterinary MedicineZagazig UniversityZagazig44519Egypt Department of Physical Therapy College of Applied Medical SciencesUniversity of Ha'ilHa'ilSaudi Arabia Department of Histology and Cell Biology Faculty of MedicineZagazig UniversityZagazig44519Egypt College of Nursing University of Ha'ilHa'ilSaudi Arabia College of Science and Humanities in Al-Kharj Physics DepartmentPlasma Technology and Material Science UnitPrince Sattam Bin Abdulaziz UniversityAl-kharj11942Saudi Arabia Physics Department Faculty of ScienceUniversity of DamiettaNew Damietta34517Egypt Spectroscopy Department Physics Research InstituteNational Research CentreDokki12622GizaEgypt Biophysics Department Faculty of ScienceCairo UniversityGizaEgypt

Developing a biomaterial for wound healing applications is still a ***,dysprosium oxide(Dy_(2)O_(3)),aluminum oxide(Al_(2)O_(3)),and graphene oxide(GO)were embedded in cast films based on polycaprolactone(PCL)to be examined for wound dressing *** techniques were used to characterize the fabricated films including X-ray diffraction(XRD),Fourier transform infrared spectroscopy(FTIR),Raman,and scanning electron microscopy(SEM),besides their biological *** thermogravimetric analysis(TGA)exhibits high thermal stability as the scaffold weight decreases slightly to 98.6%after raising the temperature from room temperature to 280℃.The cell viability was investigated and it is shown that the viable cells grow up to approximately 93%at 75μg/***,the cell attachment shows excellent behavior as the cells attach on most of the surface of the modified PCL which shows high biocompatibility.

关键词： Wound healing Polycaprolactone Dy_(2)O_(3) Al_(2)O_(3) Biocompatible Rare earths

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Wood By-Products as UV Protection:A Consequence Review

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Journal of Renewable Materials 2024年第4期12卷 699-720页

作者： Naglaa Salem el‑Sayed mohamed Hasanin Samir Kamel Cellulose and Paper Department National Research CentreCairo12622Egypt

In recent decades,the ozone layer has suffered considerable damage,increasing the entry of ultraviolet(UV)light into the atmosphere and reaching the earth’s surface,negatively affecting ***,researchers aimed to solve this problem by synthesizing advanced UV-shielding *** the other hand,developing an easy and green strategy to prepare functional materials with outstanding properties based on naturally abundant and environmentally friendly raw materials is highly desirable for sustainable *** biomass-derived materials are sustainable and biodegradable,they present a promising substitute for petroleum-based *** three main structural constituents of the plant biomass-based materials that are naturally available are cellulose,hemicellulose,and *** review details current developments using wood-based products such as cellulose,hemicellulose,and lignin in UV-shielding *** will start with assembling the structure and chemistry of cellulose,hemicellulose,and lignin,followed by their contributions to preparing UV-shielding ***,it will briefly discuss the different processing methods for the design of UV-shielding *** wood by-products offer additional opportunities to use the whole tree harvest.

关键词： UV-shielding wood cellulose lignin hemicellulose sunlight protection

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Suitability of SDN and MEC to facilitate digital twin communication over LTE-A

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Digital Communications and Networks 2024年第2期10卷 347-354页

作者： Hikmat Adhami Mohammad Alja’afreh mohamed Hoda Jiaqi Zhao Yong Zhou Abdulmotaleb el Saddik mohamed bin Zayed University of Artificial Intelligence Masdar CityAbu DhabiUnited Arab Emirates School of Computer Science and Technology China University of Mining and TechnologyXuzhou221116China School of electrical Engineering and Computer Science University of OttawaOttawaONK1N 6N5Canada

Haptic is the modality that complements traditional multimedia,i.e.,audiovisual,to evolve the next wave of innovation at which the Internet data stream can be exchanged to enable remote skills and control *** will require ultra-low latency and ultra-high reliability to evolve the mobile experience into the era of Digital Twin and Tactile *** the 5th generation of mobile networks is not yet widely deployed,Long-Term Evolution(LTE-A)latency remains much higher than the 1 ms requirement for the Tactile Internet and therefore the Digital *** work investigates an interesting solution based on the incorporation of Software-defined networking(SDN)and Multi-access Mobile Edge Computing(MEC)technologies in an LTE-A network,to deliver future multimedia applications over the Tactile Internet while overcoming the QoS *** network scenarios were designed and simulated using Riverbed modeler and the performance was evaluated using several time-related Key Performance Indicators(KPIs)such as throughput,End-2-End(E2E)delay,and *** best scenario possible is clearly the one integrating MEC and SDN approaches,where the overall delay,jitter,and throughput for haptics-attained 2 ms,0.01 ms,and 1000 packets per *** results obtained give clear evidence that the integration of,both SDN and MEC,in LTE-A indicates performance improvement,and fulfills the standard requirements in terms of the above KPIs,for realizing a Digital Twin/Tactile Internet-based system.

关键词： LTE-A 5G Digital twin Tactile Internet KPIs SDN MEC NFV Haptic

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