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Studies of Electron Energy Distribution Function (EEDF) in Lithium Va.or Excita.ion a. 2S→3D Two-Photon Resona.ce

Optics a.d Photonics Journa. 2014年第8期4卷 195-212页

作者： mohamed a. mahmoud Kholoud a. Ha.a. Physics Depa.tment Faculty of Science Sohag University Sohag Egypt Physics Depa.tment Sciences Faculty for Girls King AbdUlaziz University Jeddah KSA

We ha.e developed a.computa.iona. model which qua.tita.ively studies the Electron Energy Distribution Function (EEDF) in la.er excited lithium va.or a. 2s→3d two-photon resona.ce. a.kinetic model ha. been constructed which includes essentia.ly a.l the importa.t collisiona. ioniza.ion, photoioniza.ion, electron collisions a.d ra.ia.ive intera.tions tha. come into pla. when lithium va.or (density ra.ge 1013?- 1014 cm-3) is subject to a.sudden pulse of intense la.er ra.ia.ion (power ra.ge 105?- 106 W·cm-2) a. wa.elength 639.1 nm a.d pulse dura.ion 20 ns. The a.plied computer simula.ion model is ba.ed on the numerica. solution of the time-dependent Boltzma. equa.ion a.d a.set of ra.e equa.ions tha. describe the ra.e of cha.ge of the formed excited sta.es popula.ions. Using the mea.ured va.ues for the cross-sections a.d ra.e coefficients of ea.h physica. process considered in the model a.a.la.le in litera.ure, rela.ions a.e obta.ned a. a.function of the electron energy a.d included in the computa.iona. model. We ha.e a.so studied the time evolution a.d the la.er power dependences of the ion popula.ion (a.omic a.d molecula. ions) a. well a. the electron density which a.e produced during the intera.tion. The energy spectra.of the electrons emerging from the intera.tion conta.ns a.number of pea.s corresponding to the low-energy electrons produced by photoioniza.ion a.d collisiona. ioniza.ion such a. a.sosica.ive a.d Penning ioniza.ion processes. The non-equilibrium sha.e of these electrons occurs due to rela.a.ion of fa.t electrons produced by super-ela.tic collisions with residua. excited lithium a.oms. Moreover, a.rea.ona.le a.reement between McGeoch results a.d our ca.cula.ions for the tempora. beha.iour of the electron density is obta.ned.

关键词： Two-Photon Resona.ce Excita.ion La.er Lithium Collisiona. Ioniza.ion Energy Pooling Photoioniza.ion Electron Energy Distribution Function

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Multi-Detector Row Computed Tomogra.hy Urogra.hy (MDCTU) in the Eva.ua.ion of Microscopic Hema.uria.in a.ults

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Open Journa. of Ra.iology 2015年第1期5卷 20-27页

作者： mohamed a. mahmoud Musta.a.Z. mahmoud Moha.med a. a.i Omer mohamed E. M. Ga.a.na.i a.med a.ukonna.Ma.a. a. Fa.iri Ba.ic Sciences Depa.tment College of Medical Radiological Sciences Sudan University of Science and Technology Khartoum Sudan Ra.iology a.d Medica. Ima.ing Depa.tment College of Applied Medical Sciences Salman Bin Abdulaziz University Al-Kharj Kingdom of Saudi Arabia Depa.tment of Ra.iologic Technology College of Applied Medical Sciences Qassim University Al-Qassim Kingdom of Saudi Arabia Ra.iothera.y a.d Nuclea. Medicine Depa.tment College of Medical Radiological Sciences Sudan University of Science and Technology Khartoum Sudan

Multi-detector row computed tomogra.hy urogra.hy (MDCTU) becomes the ima.ing moda.ity of choice for eva.ua.ion of the kidneys a.d urina.y tra.t. The a.m of this study wa. to discuss a.d illustra.e the role of MDCTU, on a.32-row CT sca.ner in the eva.ua.ion a.va.iety of entities tha. were frequently a.socia.ed with microscopic hema.uria.in a.ults. This prospective cohort study wa. performed in the period of a.gust 2013 to October 2014. Fifty positive pa.ticipa.ts to microscopic hema.uria.were exa.ined a. the ra.iology depa.tment of a.nilin Dia.nostic Medica. Center a.d a.ta.ya.Medica. Center. Computed tomogra.hy urogra.hy (CTU) sca.ning wa. performed using two powerful performa.ces, high speed multi-detector row on 32-row CT sca.ners (Siemens Hea.thca.e Globa., Soma.om Emotion Duo Eco). Sta.istica. a.a.ysis wa. done through the sta.da.d Sta.istica. Pa.ka.e for the Socia. Sciences (SPSS Inc., Chica.o, IL, USa. version 15 for windows. MDCTU esta.lished the correct ca.se of microscopic hema.uria.in (44;88%) of pa.ticipa.ts. In (6;12%) of pa.ticipa.ts, no ca.se of hema.uria.wa. identified ba.ed on the sta.da.d of references. The ca.ses of hema.uria.in (41;82%) pa.ticipa.ts were disea.es in the upper urina.y tra.t, while urina.y bla.der neopla.ms (2;4%) a.d diverticulum (1;2%) were the ca.ses of hema.uria.(3;6%) in the lower urina.y tra.t. Thirty two-row MDCTU sca.ner demonstra.ed sa.isfa.tory results in the investiga.ion of microscopic hema.uria. being a.le to demonstra.e a.wide spectrum of disea.es a.fecting the urina.y tra.t is the ma.n a.va.ta.e of the technique.

关键词： Hema.uria Ima.ing Three-Dimensiona. Multi-Detector Computed Tomogra.hy Urologic Disea.es

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Tra.ma.to the solid a.domina. orga.s:The missed da.k box of colonoscopy

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World Journa. of Ga.troenterology 2024年第7期30卷 624-630页

作者： mohamed H Ema.a.Usa.a.Ma.id Ya.mine a.Elsha.r mahmoud a.Elkerda.y Dila.er Fa.ooq Ma.ik a.a.M Ma.ros Depa.tment of Hepa.ology Gastroenterologyand Infectious DiseasesKafrelsheikh UniversityKafr-Elshikh 33516Egypt Depa.tment of Medicine Alyousif HospitalAlkhobar 31952Saudi Arabia

Colonoscopy is a. integra. pa.t of the lower bowel ca.e a.d is genera.ly considered a.potentia.ly sa.e dia.nostic a.d thera.eutic procedure performed a. a.da.ca.e outpa.ient *** is a.socia.ed with different complica.ions tha. a.e not limited to a.verse events rela.ed to the bowel prepa.a.ion solutions used,the seda.ives used,but to the procedure rela.ed a. well including bleeding a.d *** to the extra.lumina. a.domina. orga.s during colonoscopy a.e uncommon,however,serious complica.ions rela.ed to the procedure ha.e been reported infrequently in the *** threa.ening injuries to the spleen,liver,pa.crea.,mesentery,a.d urina.y bla.der ha.e been reported a. ea.ly a. in *** injuries should not be overlooked by clinicia.s a.d *** increa.ing a.domina. pa.n,a.domina. distension,a.d hemodyna.ic insta.ility in a.sence of recta. bleeding should ra.se the possibility of severe orga. *** a.d hepa.ic injury following colonoscopy a.e usua.ly serious a.d ma. be life *** conserva.ive ma.a.ement ma. help,yet they usua.ly need interventiona. ra.iology or surgica. *** pa.crea.itis following colonoscopy is usua.ly mild a.d is mostly ma.a.ed *** mecha.ism of a.domina. orga. injuries during colonoscopy is not fully understood,however ma.y risk fa.tors ha.e been identified,which ca. be cla.sified a.-orga. rela.ed,procedure rela.ed,a.d loca. a.domina. *** colonoscopy a.d prior intra.a.domina. a.hesions a.e proba.ly the most releva.t risk fa.tors for these *** la.era. position,a.oida.ce of looping a.d excessive force during the procedure would proba.ly reduce the risk of such injuries.

关键词： Colonoscopy Pa.crea.itis Tra.ma Complica.ions a.hesions

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Insulin thera.y in type 2 dia.etes: Insights into clinica. effica.y, pa.ient-reported outcomes, a.d a.herence cha.lenges

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World Journa. of Dia.etes 2024年第5期15卷 828-852页

作者： mahmoud Ema.-Eldin Geha. F Ba.a.a.Ema. a.Elshorba.y Mona.S Ha.ed mohamed S a.tia Depa.tment of Pha.ma.y Pra.tice Faculty of PharmacyZagazig UniversityZagazig HFQM+872Al-Sharqia GovernorateEgypt Depa.tment of Pha.ma.y Pra.tice Faculty of PharmacyHeliopolis UniversityCairo 44519Egypt Depa.tment of Pha.ma.eutics Faculty of PharmacyZagazig UniversityZagazig 44519Al-Sharqia GovernorateEgypt Depa.tment of Interna. Medicine Faculty of MedicineZagazig UniversityZagazig 44519Al-Sharqia GovernorateEgypt Depa.tment of Community a. Fa.ulty of Medicine Zagazig UniversityZagazig 44519Al-Sharqia GovernorateEgypt

Insulin thera.y pla.s a.crucia. role in the ma.a.ement of type 2 dia.etes a. the disea.e *** the pa.t century,insulin formula.ions ha.e undergone significa.t modifica.ions a.d bioengineering,resulting in a.diverse ra.ge of a.a.la.le insulin *** products show distinct pha.ma.okinetic a.d pha.ma.odyna.ic ***,va.ious insulin regimens ha.e em-erged for the ma.a.ement of type 2 dia.etes,including premixed formula.ions a.d combina.ions of ba.a. a.d bolus *** utiliza.ion of different insulin regimens yields dispa.a.e clinica. outcomes,a.verse events,a.d,nota.ly,pa.ient-reported outcomes(PROs).PROs provide va.ua.le insights from the pa.ient’s perspective,serving a. a.va.ua.le mine of informa.ion for enha.cing hea.thca.e a.d informing clinica. *** to insulin thera.y,a.critica. pa.ient-reported outcome,significa.tly a.fects clinica. outcomes a.d is influenced by multiple *** review provides insights into the clinica. effectiveness of va.ious insulin prepa.a.ions,PROs,a.d fa.tors impa.ting insulin thera.y a.herence,with the a.m of enha.cing hea.thca.e pra.tices a.d informing clinica. decisions for individua.s with type 2 dia.etes.

关键词： a.herence Dia.etes Insulin Pa.ient-reported outcomes Pha.ma.okinetic Pha.ma.odyna.ic

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Estima.ion of Genera.ized Pa.eto under a. a.a.tive Type-II Progressive Censoring

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Intelligent Informa.ion Ma.a.ement 2013年第3期5卷 73-83页

作者： mohamed a. W. mahmoud a.med a. Solima. a.med H. a.d Ella. Ra.ha. M. El-Sa.heer Fa.ulty of Science Islamic University Madinah Saudi Arabia Ma.hema.ics Depa.tment Faculty of Science A1-Azhar University Nasr-City Cairo Egypt Ma.hema.ics Depa.tment Sohag University Sohag Egypt

In this pa.er, ba.ed on a.new type of censoring scheme ca.led a. a.a.tive type-II progressive censoring scheme introduce by Ng et a.. [1], Na.a. Resea.ch Logistics is considered. Ba.ed on this type of censoring the ma.imum likelihood estima.ion (MLE), Ba.es estima.ion, a.d pa.a.etric bootstra. method a.e used for estima.ing the unknown pa.a.eters. a.so, we propose to a.ply Ma.kov cha.n Monte Ca.lo (MCMC) technique to ca.ry out a.Ba.esia. estima.ion procedure a.d in turn ca.cula.e the credible interva.s. Point estima.ion a.d confidence interva.s ba.ed on ma.imum likelihood a.d bootstra. method a.e a.so proposed. The a.proxima.e Ba.es estima.ors obta.ned under the a.sumptions of non-informa.ive priors, a.e compa.ed with the ma.imum likelihood estima.ors. Numerica. exa.ples using rea. da.a.set a.e presented to illustra.e the methods of inference developed here. Fina.ly, the ma.imum likelihood, bootstra. a.d the different Ba.es estima.es a.e compa.ed via.a.Monte Ca.lo simula.ion study.

关键词： Genera.ized Pa.eto (GP) Distribution a. a.a.tive Type-II Progressive Censoring Scheme Ba.esia. a.d Non-Ba.esia. Estima.ions Gibbs a.d Metropolis Sa.pler Bootstra.

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Pyrona.idine combined with dimina.ene a.etura.e inhibits Ba.esia.in vitro a.d in vivo

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a.ia. Pa.ific Journa. of Tropica. Biomedicine 2024年第3期14卷 93-99页

作者： Shima. a.d El-Sa.a. El-Sa.ed mohamed Z.Sa.ed-a.med Sha.ma. a.med a.a. a.i Noura. a.sa.a.n Na.a.ish a.a. mahmoud S.a.khouda.y Ikuo Iga.a.hi mohamed a.do Rizk Na.iona. Resea.ch Center for Protozoa. Disea.es Obihiro University of Agriculture and Veterinary MedicineInada-ChoObihiroHokkaido 080-8555Japan Depa.tment of Biochemistry a.d Chemistry of Nutrition Faculty of Veterinary MedicineMansoura UniversityMansoura 35516Egypt Depa.tment of Clinica. Pha.ma.y College of PharmacyJazan UniversityJazan 45142Saudi Arabia Medica.-Surgica. Depa.tment College of NursingJouf UniversitySakaka 72388Saudi Arabia Critica. Ca.e a.d Emergency Nursing Faculty of NursingMansoura UniversityEgypt College of Nursing Jouf UniversitySakaka 72388Saudi Arabia Fa.ulty of Pha.ma.y Mansoura UniversityMansoura 35516DakahliaEgypt Depa.tment of Interna. Medicine a.d Infectious Disea.es Faculty of Veterinary MedicineMansoura UniversityMansoura 35516Egypt

Objective:To eva.ua.e the combina.ion thera.y of pyrona.idine tetra.hospha.e a.d dimina.ene a.etura.e a.a.nst Ba.esia.in vitro a.d in ***:Bioinforma.ic a.a.ysis wa. performed using a.om pa.r *** in vitro combina.ion test wa. performed a.a.nst Ba.esia.bovis a.d Theileria.***,the in vivo chemothera.eutic effica.y of pyrona.idine tetra.hospha.e in combina.ion with dimina.ene a.etura.e wa. investiga.ed a.a.nst the growth of Ba.esia.microti in mice using a.fluorescence inhibitory ***:Pyrona.idine tetra.hospha.e a.d dimina.ene a.etura.e exhibited nea.ly simila. molecula. *** in vitro combina.ion of pyrona.idine tetra.hospha.e a.d dimina.ene a.etura.e wa. synergistic on Ba.esia.bovis a.d a.ditive on Theileria.*** a.dition,5 mg/kg pyrona.idine tetra.hospha.e combined with 10 mg/kg dimina.ene a.etura.e inhibited Ba.esia.microti growth significa.tly compa.ed with those observed a.ter trea.ment with 25 mg/kg dimina.ene a.etura.e a.one from da. 6 post trea.ment to da. 12 post *** combina.ion thera.y a.so norma.ized the hema.ologica. pa.a.eters of infected ***:a. ora. dose of pyrona.idine tetra.hospha.e combined with a.subcuta.eous dose of dimina.ene a.etura.e inhibits Ba.esia.in vitro a.d in mice,suggesting it might be a.new pa.a.igm for the trea.ment of ba.esiosis.

关键词： Ba.esia Pyrona.idine tetra.hospha.e Dimina.ene a.etura.e Ba.esiosis Theileria

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a.New Speed Limit Recognition Methodology Ba.ed on Ensemble Lea.ning:Ha.dwa.e Va.ida.ion

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Computers, Ma.eria.s & Continua 2024年第7期80卷 119-138页

作者： mohamed Ka.ra. Nesrine Triki mohamed Ksa.tini ESME ESME Research LabIvry Sur Seine94200France CEM Lab ENISUniversity of SfaxSfax3038Tunisia

a.va.ced Drivera.sista.ce Systems(a.a.)technologies ca. a.sist drivers or be pa.t of a.toma.ic driving systems to support the driving process a.d improve the level of sa.ety a.d comfort on the *** Sign Recognition System(TSRS)is one of themost importa.t components *** the cha.lengeswith TSRS is being a.le to recognize roa. signs with the highest a.cura.y a.d the shortest processing ***,this pa.er introduces a.new rea. time methodology recognizing Speed Limit Signs ba.ed on a.trio of developed ***,the Speed Limit Detection(SLD)module uses the Ha.r Ca.ca.e technique to genera.e a.new SL detector in order to loca.ize SL signs within ca.tured ***,the Speed Limit Cla.sifica.ion(SLC)module,fea.uring ma.hine lea.ning cla.sifiers a.ongside a.newly developed model ca.led DeepSL,ha.nesses the power of a.CNN a.chitecture to extra.t intrica.e fea.ures from speed limit sign ima.es,ensuring efficient a.d precise *** a.dition,a.new Speed Limit Cla.sifiers Fusion(SLCF)module ha. been developed by combining tra.ned ML cla.sifiers a.d the DeepSL model by using the Dempster-Sha.er theory of belief functions a.d ensemble lea.ning’s voting *** rigorous softwa.e a.d ha.dwa.e va.ida.ion processes,the proposedmethodology ha. a.hieved highly significa.t F1 scores of 99.98%a.d 99.96%for DS theory a.d the votingmethod,***,a.prototype encompa.sing a.l components demonstra.es outsta.ding relia.ility a.d effica.y,with processing times of 150 ms for the Ra.pberry Pi boa.d a.d 81.5 ms for the Na.o Jetson boa.d,ma.king a.significa.t a.va.cement in TSRS technology.

关键词： Driving a.toma.ion a.va.ced driver a.sista.ce systems(a.a.) tra.fic sign recognition(TSR) a.tificia. intelligence ensemble lea.ning belief functions voting method

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Childhood a.thma.bioma.kers including zinc: a. explora.ory crosssectiona. study

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World Journa. of Clinica. Pedia.rics 2024年第1期13卷 31-40页

作者： Hoda.a.ef a.delsa.ta. Ibra.im Mona.Mohsen Boles Sa.ep a.iz Ha.na.Dina.mahmoud Kha.ed mohamed a.delha.id El-Kha.ha. Pedia.ric Clinica. Nutrition Unit Faculty of MedicineCairo UniversityCairo 12613Egypt Depa.tment of Pedia.rics Faculty of MedicineCairo UniversityCairo 12613Egypt Depa.tment of Clinica. Pa.hology Faculty of MedicineCairo UniversityCairo 12613Egypt

Ba.KGROUND Childhood bronchia. a.thma.Ba.is a.chronic infla.ma.ory respira.ory *** conditions,including zinc deficiency,ca. a.fect such a.lergic *** To outline the difference in serum zinc levels between a.thma.ic children a.d hea.thy *** a.cross-sectiona. study wa. ca.ried out a. Children’s Hospita.,Ca.ro University,investiga.ing serum zinc levels in children with Ba.n=40)a.d hea.thy children(n=21).Other ma.kers included serum ferritin,iron,hemoglobin(Hb),a.d immunoglobulin E(IgE)*** t-tests a.d Ma.n-Whinny tests were used for *** Kruska.-Wa.lis test wa. a.plied to compa.e serum ferritin a.d IgE levels with rega.d to a.thma.***'s ra.k correla.ion wa. performed to explore the rela.ionship between serum ferritin levels a.d both iron a.d Hb levels in a.thma.ic *** Children with Ba.ha. higher levels of zinc,yet the difference wa. not significa.t(P=0.115).Serum ferritin a.d IgE levels were significa.tly higher in a.thma.ic children(P=0.006 a.d 0.001,respectively),yet their levels did not differ significa.tly by severity(P=0.623 a.d 0.126,respectively).There wa. a.nonsignifica.t wea. correla.ion between serum ferritin levels a.d both serum iron a.d Hb *** Serum zinc levels do not seem to differ between a.thma.ic children a.d hea.thy *** ferritin levels ma. be a.ma.ker of a.thma.*** IgE levels a.e not ma.kers of a.thma.severity.

关键词： Children a.thma Zinc Ferritin

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a.Distributiona.ly Robust Optimiza.ion Scheduling Model for Regiona. Integra.ed Energy Systems Considering Hot Dry Rock Co-Genera.ion

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Computer Modeling in Engineering & Sciences 2024年第8期140卷 1387-1404页

作者： Ha. Qi mohamed Sha.a. a.dres a.nuk a.ria. Ilinca.mohamed a.mohamed College of Electrica. a.d New Energy China Three Gorges UniversityYichang443002China Depa.tment of Industria. Engineering College of EngineeringKing Saud UniversityRiyadh11421Saudi Arabia Institute of Forestry a.d Engineering Estonian University of Life SciencesTartu51006Estonia Depa.tment of Mecha.ica. Engineering école de Technologie SupérieureMontréalQC H3C 1K3Canada Electrica. Engineering Depa.tment Faculty of EngineeringMinia UniversityMinia61519Egypt

Hot dry rock(HDR)is rich in reserve,widely distributed,green,low-ca.bon,a.d ha. broa. development potentia. a.d *** this pa.er,a.distributiona.ly robust optimiza.ion(DRO)scheduling model for a.regiona.ly integra.ed energy system(RIES)considering HDR co-genera.ion is ***,the HDR-enha.ced geotherma. system(HDR-EGS)is introduced into the ***-EGS rea.izes the thermoelectric decoupling of combined hea. a.d power(CHP)through coordina.ed opera.ion with the regiona. power grid a.d the regiona. hea. grid,which enha.ces the system wind power(WP)feed-in ***,pea.-hour loa.s a.e shifted using price dema.d response guida.ce in the context of time-of-da. ***,the optimiza.ion objective is esta.lished to minimize the tota. cost in the RIES scheduling cycle a.d construct a.DRO scheduling model for RIES with *** simula.ing a.rea. sma.l-sca.e RIES,the results show tha. HDR-EGS ca. effectively promote WP consumption a.d reduce the opera.ing cost of the system.

关键词： Energy ha.vesting integra.ed energy systems optimum scheduling time-of-use pricing dema.d response geotherma. energy

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Ca.culus bovis in hepa.ocellula. ca.cinoma.Tumor molecula. ba.is,Wnt/β-ca.enin pa.hwa. role,a.d protective mecha.ism

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World Journa. of Ga.troenterology 2024年第35期30卷 3959-3964页

作者： Kha.ed mohamed mohamed Koriem Depa.tment of Medica. Physiology Medical Research and Clinical Studies InstituteNational Research CentreGiza 12622Egypt

In this editoria.,we comment on the recent a.ticle by Hua.g et *** editoria. focuses specifica.ly on the molecula. mecha.isms of hepa.ocellula. ca.cinoma.HCC),mecha.ism of Wnt/β-ca.enin pa.hwa. in HCC,a.d protective mecha.ism of Ca.culus bovis(CB)in *** ca.cer is the fourth most common ca.se of ca.cer-rela.ed dea.hs *** most preva.ent kind of prima.y liver ca.cer,HCC,is typica.ly brought on by long-term vira. infections(hepa.itis B a.d C),non-a.coholic stea.ohepa.itis,excessive a.cohol consumption,a.d other conditions tha. ca. ca.se the liver to become chronica.ly infla.ed a.d *** is a.wellknown tra.itiona. remedy in China.a.d Ja.a. a.d ha. been used extensively to trea. a.va.iety of disea.es,such a. high fever,convulsions,a.d *** in lipid meta.olism,cholesterol meta.olism,bile a.id meta.olism,a.cohol meta.olism,a.d xenobiotic detoxifica.ion lea. to fa.ty liver disea.e a.d liver ***,which is a.trica.boxylic a.id cycle intermedia.e,is vita. to energy production a.d mitochondria. *** is a.so thought to be a.signa.ing molecule in meta.olism a.d in the development a.d sprea. of liver *** Wnt/β-ca.enin pa.hwa. is ma.e up of a.group of proteins tha. a.e essentia. for both a.ult tissue homeosta.is a.d embryonic *** is frequently ca.sed by the dysregula.ion of the Wnt/β-ca.enin signa.ing *** HCC liver ca.cinogenesis,Wnt/β-ca.enin signa.ing is a.tiva.ed by the expression of downstrea. ta.get *** between the liver a.d the gut exists via.the porta. vein,bilia.y tra.t,a.d systemic ***"gutliver a.is"controls intestina. *** of the ma.n fa.tors contributing to the development,progression,a.d trea.ment resista.ce of HCC is the a.norma. a.tiva.ion of the Wnt/β-Ca.enin signa.ing ***,understa.ding this pa.hwa. is essentia. to trea.ing *** ingredients of CB,pa.ticula.ly olea.olic a.id,ergosterol,a.d ursolic a.id,ha.e a.ti-p

关键词： Hepa.ocellula. ca.cinoma MicroRNa. Wnt/β-ca.enin pa.hwa. Ca.culus bovis a.optosis

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