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Agricultural Sciences 2015年第1期6卷 152-158页

作者： Bakry Ahmed Bakry Osama Anour Nofal mohamed soliman zeidan Mahmoud Hozayn Field Crops Department National Research Centre Cairo Egypt Plant Nutrition Department National Research Centre Cairo Egypt

Two field experiments were carried out at the experimental station of National Research Centre, Al-Nubaria District, El-Behira Governorate, Egypt during winter seasons of 2011/2012 and 2012/2013 to study the effect of potassium soil application at the rates (0, 50, 75 and 100 kg/fed.) with or without chelated zinc foliar application 5% at the rate of (0.03 kg/fed.) on the yield and quality of two flax varieties (Sakha-2 and Amon) in newly reclaimed sandy soil. The obtained results could be summarized as follow: Sakha-2 variety significantly surpassed Amon in plant height, technical length, number of branches/plant, seed yield/plant, straw yield/plant, 1000 seed weight, seed yield/fed., straw yield/fed., fiber %, fiber yield/fed. and oil yield/fed. Amon variety surpassed Sakha-2 in fruiting zone length, number of capsules/plant and oil % in both seasons. Potassium soil application at the rate of (100 kg/fed.) with chelated zinc foliar application 5% at the rate of (0.03 kg/fed.) gave the highest value for all studied characters.

关键词： Flax Potassium Fertilizer Zinc Fertilizer

Linearly and Quadratically Separable Classifiers Using Adaptive Approach

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Journal of Computer Science & Technology 2011年第5期26卷 908-918页

作者： mohamed Abdel-Kawy mohamed Ali soliman Rasha M.Abo-Bakr Department of Computer and Systems Engineering Faculty of EngineeringZagazig UniversityZagazigEgypt Departement of Mathematics Faculty of ScienceZagazig UniversityZagazigEgypt

This paper presents a fast adaptive iterative algorithm to solve linearly separable classification problems in R *** each iteration,a subset of the sampling data （n-points,where n is the number of features） is adaptively chosen and a hyperplane is constructed such that it separates the chosen n-points at a margin and best classifies the remaining *** classification problem is formulated and the details of the algorithm are ***,the algorithm is extended to solving quadratically separable classification *** basic idea is based on mapping the physical space to another larger one where the problem becomes linearly *** illustrations show that few iteration steps are sufficient for convergence when classes are linearly *** nonlinearly separable data,given a specified maximum number of iteration steps,the algorithm returns the best hyperplane that minimizes the number of misclassified points occurring through these *** with other machine learning algorithms on practical and benchmark datasets are also presented,showing the performance of the proposed algorithm.

关键词： linear classification quadratic classification iterative approach adaptive technique

Robust Malicious Executable Detection Using Host-Based Machine Learning Classifier

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Computers, Materials & Continua 2024年第4期79卷 1419-1439页

作者： Khaled soliman mohamed Sobh Ayman M.Bahaa-Eldin Department of Computer and Systems Engineering Ain Shams UniversityCairo11517Egypt Department of Computer Engineering Technology ElSewedy University of TechnologyCairo44629Egypt

The continuous development of cyberattacks is threatening digital transformation endeavors worldwide and leadsto wide losses for various organizations. These dangers have proven that signature-based approaches are insufficientto prevent emerging and polymorphic attacks. Therefore, this paper is proposing a Robust Malicious ExecutableDetection (RMED) using Host-based Machine Learning Classifier to discover malicious Portable Executable (PE)files in hosts using Windows operating systems through collecting PE headers and applying machine learningmechanisms to detect unknown infected files. The authors have collected a novel reliable dataset containing 116,031benign files and 179,071 malware samples from diverse sources to ensure the efficiency of RMED *** most effective PE headers that can highly differentiate between benign and malware files were selected totrain the model on 15 PE features to speed up the classification process and achieve real-time detection formalicious executables. The evaluation results showed that RMED succeeded in shrinking the classification timeto 91 milliseconds for each file while reaching an accuracy of 98.42% with a false positive rate equal to 1.58. Inconclusion, this paper contributes to the field of cybersecurity by presenting a comprehensive framework thatleverages Artificial Intelligence (AI) methods to proactively detect and prevent cyber-attacks.

关键词： Portable executable malware intrusion detection cybersecurity zero-day threats Host IntrusionDetection System(HIDS) machine learning Anomaly-based Intrusion Detection System(AIDS) deep learning

A spatiotemporal algebra in Hadoop for moving objects

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Geo-Spatial Information Science 2018年第2期21卷 102-114页

作者： mohamed S.Bakli Mahmoud A.Sakr Taysir Hassan A.soliman Faculty of Computers and Information Assiut UniversityAssiutEgypt Faculty of Computer and Information Sciences Ain Shams UniversityCairoEgypt Universitélibre de Bruxelles BruxellesBelgium

Spatiotemporal data represent the real-world objects that move in geographic space over *** enormous numbers of mobile sensors and location tracking devices continuously produce massive amounts of such *** leads to the need for scalable spatiotemporal data management *** systems shall be capable of representing spatiotemporal data in persistent storage and in *** shall also provide a range of query processing operators that may scale out in a cloud ***,very few researches have been conducted to meet this *** paper proposes a Hadoop extension with a spatiotemporal *** algebra consists of moving object types added as Hadoop native types,and operators on top of *** Hadoop file system has been extended to support parameter passing for files that contain spatiotemporal data,and for operators that can be unary or *** the types and operators are accessible for the MapReduce *** an extension allows users to write Hadoop programs that can perform spatiotemporal *** queries may call more than one operator for different jobs and keep these operators running in *** paper describes the design and implementation of this algebra,and evaluates it using a benchmark that is specific to moving object databases.

关键词： Spatiotemporal algebra Hadoop MapReduce moving objects

Transcriptome analysis revealing the mechanism of soybean protein isolates and soybean peptides on Lacticaseibacillus rhamnosus Lra05

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Food Bioscience 2022年第3期47卷 736-744页

作者： Yinxiao Zhang Shuya Zhu Chi Zhang mohamed mohamed soliman He Li Xinqi Liu Beijing Advanced Innovation Center for Food Nutrition and Human Health Beijing Engineering and Technology Research Center of Food AdditivesNational Soybean Processing Industry Technology Innovation CenterBeijing Technology and Business UniversityBeijing100048China Clinical Laboratory Sciences Department Turabah University CollegeTaif University21995Saudi Arabia

To further investigate the promoting effect of soybean protein and peptides on Lacticaseibacillus rhamnosus Lra05(*** Lra05),the overall changes of gene expression of it was investigated through transcriptome analysis treated with dPEP and dSPI The results showed that there were 890,113,and 1073 differentially expressed genes(DEGs)in dPEP/MRS,dSPI/MRS and dPEP/dSPI comparison,***,we found dPEP could promote the expression of acc and fab family genes related to fatty acid biosynthesis,but dSPI played the opposite ***,dPEP stimulated genes clustered in pur family and ribosome protein,responsible for purine and protein ***,dPEP suppressed genes regulating peptides and amino acids transportation and dSPI specially inhibited the pyr family genes involved in pyrimidine *** data revealed the knowledge about the metabolic pathways affected by dPEP and dSPI and provide a preliminary understanding of the relationship between soybean proteins and peptides and *** Lra05.

关键词： Lacticaseibacillus rhamnosus Soybean protein isolates Soybean peptides Transcriptome analysis

Estimation of the novel antipyretic, anti-inflammatory, antinociceptive and antihyperlipidemic effects of silymarin in Albino rats and mice

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Asian Pacific Journal of Tropical Biomedicine 2015年第8期5卷 605-609页

作者： mohamed Mahmoud Amin Mahmoud soliman Arbid Department of Pharmacology Medical Division National Research Centre

Objective: To evaluate the other pharmacological actions of silymarin in Albino rats and mice such as antipyretic, anti-inflammatory, antinociceptive and antihyperlipidemic effects. Methods: Rats were injected intramuscularly with pyrogenic dose of brewer's yeast for the antipyretic test of silymarin. Another group of rats injected with 0.1 mL of 1% carrageenan solution in saline at the subplanter area of the right hind paw for the anti-inflammatory test of silymarin. Another group of mice tested by hot plate method for determination of antinociceptive effect of silymarin. Hyperlipidemia was induced using high fat diet for 2 months to estimate the antihyperlipidemic activity of silymarin. Results: Silymarin showed a significant antipyretic effect of both doses(50 and 100 mg/kg) compared with control untreated group. Moreover, silymarin elucidated a significant anti-inflammatory effect of both doses reflected on the decrease of the rat paw edema every hour interval for 4 h after administration in comparison with control positive group. By the same taken, both doses of silymarine revealed a significant antinociceptive action in hot plate method at 30 and 60 min post administration. Besides, it lowered significantly the serum levels of prostaglandin E2, tumor necrosis factor alpha and interleukin 1 beta after 2 h of silymarin administration in carrageenan induced rat paw edema besides the significant decrease of total cholesterol, triglycerides, low density lipoprotein and significantly elevated high density lipoprotein after 2 weeks of silymarin administration. Conclusions: These outcomes delivered a new vision into the possible pharmacological mechanisms by which silymarin advances antipyretic, anti-inflammatory, antinociceptive and antihyperlipidemic effects.

关键词： Silymarin Antipyretic Anti-inflammatory Antinociceptive Antihyperlipidemic PGE2 TNF-α IL-1β

Evaluation of GALAD Score in Diagnosis and Follow-up of Hepatocellular Carcinoma after Local Ablative Therapy

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Journal of Clinical and Translational Hepatology 2023年第2期11卷 334-340页

作者： Rasha Eletreby Marwa Elsharkawy Alaa Awad Taha mohamed Hassany Amr Abdelazeem mohamed El-Kassas Ahmed soliman Endemic Medicine Department Faculty of MedicineCairo UniversityCairoEgypt Clinical and Chemical Pathology Department Faculty of MedicineCairo UniversityCairoEgypt Hepatogastroenterology Department Theodore Bilharz Research InstituteGizaEgypt Hepatogastroenterology Department National Hepatology and Tropical Medicine Research InstituteCairoEgypt Endemic Medicine Department Faculty of MedicineHelwan UniversityCairoEgypt

Background and Aims:Strategies for detection of early hepatocellular carcinoma(HCC)are still *** GALAD score is a serum biomarker-based model designed to predict the probability of having *** aimed to assess the ability of GALAD score to diagnose early HCC and its validity to follow patients after local ablation ***:This multicenter prospective study included 108 patients in two groups,58 HCC patients(67 focal lesions)with local ablative therapy(study group),and a control group of 50 patients with liver *** GALAD scores of the study and control groups,and of the HCC patients before and after ablative therapy were ***:Most patients were men(74.1%in study group and 76%in controls)with hepatitis C virus infection(98.30%in the study group,and 94%in controls).GALAD scores were significantly higher in HCC patients than in those with benign cirrhosis(2.65 vs.−0.37,p=0.001).Ablative therapy was successful in 94.4%of focal lesions<2 cm,and in 86.10%of 2–5 cm *** GALAD score was also significantly lower at 1 month after ablation in patients with well-ablated tumors(2.19 vs.0.98,p=0.001).The best cutoff values of GALAD score for diagnosis of early HCC,and for prediction of well ablation of HCC were 0.74 and≤3.31(areas under the curve of 0.92 and 0.75,sensitivities of 84.48%and 76.19%,specificities of 89.13%and 83.33%,positive predictive values of 90.74%and 94.1%,and negative predictive values of 82%and 35.7%respectively).Conclusion:The GALAD score was effective for the diagnosis of early HCC and for followup after ablative therapy.

关键词： GALAD score HCC Ablative therapy Liver cirrhosis Egypt

Characterization of some bacterial strains isolated from the Egyptian eastern and northern coastlines with antimicrobial activity of Bacillus zhangzhouensis OMER4

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Acta Oceanologica Sinica 2022年第3期41卷 86-93页

作者： mohamed O.soliman Waleed B.Suleiman mohamed M.Roushdy Eman N.Elbatrawy Ahmed M.Gad Department of Botany and Microbiology Faculty of ScienceAl-Azhar UniversityCairo 11884Egypt The Regional Center for Mycology and Biotechnology Al-Azhar UniversityCairo 11884Egypt Microbiology Laboratory Marine Environmental DivisionNational Institute of Oceanography and FisheriesAlexandria 11865Egypt

Marine microorganisms were considered to be important sources of marine bioactive *** major objective of the study was to isolate and characterize bacteria with antimicrobial activities from the various marine environment of *** this respect,thirty-five bacterial isolates were recovered from sediment samples collected from different spots along the Egyptian Red Sea coastline and Alexandria coastline during the summer season of 2017 and *** to the morphological,physiological,and biochemical characteristics,the bacterial isolates were clustered into 13 groups designated as A,B,…,***,14 Gram-negative and 21 Grampositive bacteria were *** isolated bacterial strains were screened for their potentiality for antimicrobial agent(s)production against ten indicator *** Mo13 was showed high antimicrobial activity against all empirical ***,the most promising marine bacterial isolate with code MO13 was identified as Bacillus zhangzhouensis OMER4 according to the phenotypic characterization through morphological,physiological,and biochemical tests as well as genotypic characterization through the 16 S rDNA *** bioactive components were extracted with ethyl acetate,then analyzed using GC-MS and the substantial component was recognized as phenol,2,4-bis(1,1-dimethyl ethyl).

关键词： marine bacteria natural product Egyptian coastline antimicrobial Bacillus zhangzhouensis GC-MS characterization

Effect of single subconjunctival injection of bevacizumab on primary pterygium:clinical,histopathological and immunohistochemical study

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International Journal of Ophthalmology(English edition) 2018年第5期11卷 797-801页

作者： Tarek A mohamed Wael soliman Ahmed M.Fathalla Abeer El Refaie Department of Ophthalmology Assiut University Hospital Department of Pathology Faculty of MedicineAssiut University

AIM：To evaluate the effect（clinically,histopathologically and immunohistochemically） and safety of a single intrapterygium injection of ***：Prospective interventional study comprised 40 eyes of 40 patients with primary fleshy pterygia who attended the Outpatient Clinic of Department of Ophthalmology,Assiut University Hospitals,Egypt from May 2015 to May *** were randomly classified into 2 groups：the first group received a single intralesional injection of bevacizumab（Avastin;Genentech,San Francisco,CA,USA）;the second group comprised patients who did not receive subconjunctival *** of pterygium and conjunctival auto graft was done in both *** excised pterygium tissues were subjected to histopathological and immunohistochemical ***：The study comprised 40 eyes of 40 patients（33 men,7 women） of age range from 31-58 *** study group included 22 *** control group included 18 eyes.A decrease in the vascularity of the pterygium was noted in all injected *** mean vessel count was higher in non-injected pterygia than that in injected pterygia and the difference was statistically significant（P=0.001）.Also,the mean vessel count in both groups was significantly higher than normal conjunctive（P=0.005 and 0.001）.A statistically significant difference in vascular endothelial growth factor（VEGF） expression between injected and non-injected cases was detected in the epithelial,stromal and endothelial cells（P=0.0001,0.016,0.014）.No serious intraoperative complications occurred in both ***：The use of single intra lesional injection of Avastin in pterygium decreased vascularity and decreased VEGF expression in injected pterygium after one *** study proved the effect of single intra lesional injection of Avastin on *** studies may enable limiting the need for surgery and improve quality of life for patients with pterygia.

关键词： pterygiurn vascularity bevacizumab vessel count

Evaluation of phosphorus bioavailability in El Mex Bay and Lake Mariut sediments

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International Journal of Sediment Research 2017年第3期32卷 432-441页

作者： Naglaa F.soliman Gehan M.El Zokm mohamed A.Okbah Department of Environmental Studies Institute of Graduate Studies and Research University of Alexandria National Institute of Oceanography and Fisheries

Phosphorus(P) fractions and their bioavailability in the sediments from El Mex Bay and Lake Mariut in Egypt were investigated using different chemical extraction methods. Sodium bicarbonate(NaHC03)extractable P(Olsen-P) was the largest fraction(14.42%), followed by algal available P(AAP)(3.56%),water soluble P(WSP)(0.79%), and readily desorbable P(RDP)(0.06%) for El Mex Bay. While AAP contributed 9.94% to total P in sediments from Lake Mariut, Olsen-P 8.53%, WSP 4.11%, and RDP 0.92%.Summation of the bioavailable P fractions didn’t exceed the sediment quality guidelines, and, therefore, P doesn’t represent a danger to marine organisms. Correlation coefficients showed that no apparent relations between total P(TP) and iron(Fe), aluminum(Al), and calcium(Ca) in the sediments. Furthermore, Fe:P ratio was less than 15 indicting that there was not enough Fe in surface sediments to bind to P at most of the sampling sites. The positive correlation between TP and organic matter(OM) for Lake Mariut and El Mex Bay sediments indicated that the organic matter content of the sediment was a useful predictor of the total phosphorus content. Data from this study constitute a baseline of phosphorus bioavailability in sediments from El Mex Bay and Lake Mariut and could be used as a reference for future studies on the changes of bioavailable and residual phosphorus fractions over time.

关键词： Phosphorus bioavailability Sediments El Mex Bay Lake Mariut