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Postnatal ex vivo rat model for longitudinal bone growth investigations

Animal Models and Experimental Medicine 2019年第1期2卷 34-43页

作者： Adamu Abdul Abubakar Sahar Mohammed Ibrahim Ahmed Khalaf Ali Kareem Obayes Handool Mohammad Shuaib Khan mohamed noordin mustapha Tengku Azmi Ibrahim Ubedullah Kaka Loqman Mohamad Yusof Department of Companion Animal Medicine and Surgery Universiti Putra Malaysia Department of Veterinary Surgery and Radiology Usmanu Danfodiyo University Department of Surgery and Theriogenology College of Veterinary Medicine University of Mosul Faculty of Veterinary and Animal Science Gomal University Department of Veterinary Pathology and Microbiology Universiti Putra Malaysia Department of Pre-Clinical Veterinary Sciences Universiti Putra Malaysia Laboratory of Sustainable Animal Production and Biodiversity Institute of Tropical Agriculture and Food SecurityUniversiti Putra Malaysia

Background: Chondrocytes in the growth plate(GP) undergo increases in volume during different cascades of cell differentiation during longitudinal bone growth. The volume increase is reported to be the most significant variable in understanding the mechanism of long bone ***: Forty-five postnatal Sprague-Dawley rat pups, 7-15 days old were divided into nine age groups(P7-P15). Five pups were allocated to each group. The rats were sacrificed and tibia and metatarsal bones were harvested. Bone lengths were measured after 0, 24, 48, and 72 hours of ex vivo incubation. Histology of bones was carried out, and GP lengths and chondrocyte densities were ***: There were significant differences in bone length among the age groups after 0 and 72 hours of incubation. Histological sectioning was possible in metatarsal bone from all age groups, and in tibia from 7-to 13-day-old rats. No significant differences in tibia and metatarsal GP lengths were seen among different age groups at 0 and 72 hours of incubation. Significant differences in chondrocyte densities along the epiphyseal GP of the bones between 0 and 72 hours of incubation were observed in most of the age ***: Ex vivo growth of tibia and metatarsal bones of rats aged 7-15 days old is possible, with percentage growth rates of 23.87 ± 0.80% and 40.38 ± 0.95%measured in tibia and metatarsal bone, respectively. Histological sectioning of bones was carried out without the need for decalcification in P7-P13 tibia and P7-P15 metatarsal bone. Increases in chondrocyte density along the GP influence overall bone elongation.

关键词： bone growth model chondrocytes endochondral ossification growth plate Sprague-Dawley rat

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LMI solutions for H-two and H-infinity decentralized controllers applied to an aerothermic process

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控制理论与应用（英文版） 2013年第2期11卷 247-254页

作者： Najib BENNIS mustapha RAMZI mohamed HALOUA Hussein YOULAL ENSET de Rabat Avenue de l'Arme'e Royale Madinat Al Irfane 10100 B. P. 6207 Rabat-InstitutsMorocco LASTIMI EST de sale' Universite' Mohamed V Agdal Avenue Prince sidi Mohammed B.P 227 Sale' Me'dinaMorocco EMI Avenue IbnSina B. P. 765 Agdal RabatMorocco UFR Automatique et Technologies de l'Information Faculte' des Sciences de Rabat Avenue Ibn Batouta B. P. 1014 RabatMorocco

In this paper, we present a linear matrix inequality （LMI）-based solution to implement H-two and H- infinity decentralized robust control strategies. Appropriate parametrization of optimal H-two and H-infinity controllers is used. The general formulation of the decentralized control design leads to the optimal determination of both the state feedback gains and the observer gains of the decentralized controllers. This formulation is two folds： first, a centralized controller is obtained, and then, a simplified decentralized solution is derived by optimizing only the observer gains. The mathematical determination of these gains is formulated as an LMI optimization problem that can be easily solved using LMI solvers. As an experimental evaluation of these controllers, a real time application to an aerothermic process is carried out. A continuous-time model of the process obtained with a suitable direct continuous-time identification approach is elaborated. Results illustrating the real performance obtained from the H-two and H-infinity decentralized controllers are di^cu^ge.d and comnare, d with th~ ce^ntraliTed nn^g

关键词： Parametrization approach Decentralized control H-two/H-infinity control Parameters optimization Lin-ear matrix inequality (LMI) Subspace identification Aerothermic process

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Effect of the synthesis route on the structural and dielectric properties of SrBi1.8Y0.2Nb2O9 ceramics

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International Journal of Minerals,Metallurgy and Materials 2018年第11期25卷 1304-1312页

作者： mohamed Afqir Amina Tachafine Didier Fasquelle mohamed Elaatmani Jean-Claude Carru Abdelouahad Zegzouti mustapha El Hammioui Laboratoire des Sciences des Matériaux Inorganiques et leurs Applications Facultédes Sciences SemlaliaUniversitéCadi AyyadMarrakech 40000Maroc Unite de Dynamique et Structure des Materiaux Moleculaires Universite du Littoral-Cote d’OpaleCalais 62100France Laboratoire de recherche sur la réactivitédes matériaux et l’optimisation des procédés Facultédes Sciences SemlaliaUniversitéCadi Ayyad 40000MarrakechMaroc

This work is devoted to the synthesis and characterization of yttrium-doped SrBi_2Nb_2O_9 ceramics prepared by three methods: solid state reaction, co-precipitation, and hydrothermal. Multiple characterizations, specifically scanning electron microscopy(SEM), X-ray powder diffraction(XRD), and Fourier transform infrared spectroscopy(FTIR), were used to validate the structural feature. The crystallite size was estimated by Scherrer's formula and the Williamson–Hall plot. The effect of the process on the band intensities of the FTIR spectra was investigated. The crystallite size and microstructure of ceramics prepared from different synthesis processes were strongly influenced by the sinterability. SEM images revealed nanograin ceramics for materials prepared by co-precipitation and hydrothermal methods and micrograin ceramics prepared by the solid state method. The synthesized compounds underwent phase transitions at 480–465°C. The dielectric and electrical properties of these Y-doped SrBi_2Nb_2O_9 ceramics appear to be dependent on the grain size.

关键词： Aurivillius,synthesis routes crystallite size microstructure dielectric

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Spectral transformation-based technique for reducing effect of limited pre-correlation bandwidth in the GNSS receiver filter in presence of noise and multipath

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Journal of Systems Engineering and Electronics 2020年第2期31卷 252-265页

作者： TITOUNI Salem ROUABAH Khaled ATIA Salim FLISSI mustapha MEZAACHE Salaheddine BOUHLEL mohamed Salim Electronics and Advanced Telecommunications Laboratory of Electronics Department University of Mohamed El Bachir El IbrahimiBordj Bou Arreridj 34031Algeria Sciences of Electronics Technologies of Information and Telecommunications Research UnitHigher Institute of Biotechnology of SfaxSfax 3038Tunisia

This paper proposes an efficient scheme to reduce the pre-correlation bandwidth effect in the global navigation satellite system(GNSS)receiver filtering *** is mainly based on the application of a spectral transformation to the satellite-emitted signal that effectively reduces its *** the receiver's end,this operation causes the spreading of noise over a much wider band than that used by the radio frequency ***,the resulting auto-correlation function in the acquisition process acquires properties that enhance considerably the performance of the receiver in the presence of the multipath and noise disturbing *** simulation results demonstrate that the proposed method is a plausible solution for both multipath and noise problems in the GNSS applications for any limited value of the pre-correlation bandwidth in the receiver filter.

关键词： precorrelation bandwidth spectral transformation multipath noise

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Partition of Unity Finite Element Analysis of Nonlinear Transient Diffusion Problems Using p-Version Refinement

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Computer Modeling in Engineering & Sciences 2020年第7期124卷 61-78页

作者： Abdelkarim El Kahoui mustapha Malek Nouh Izem MShadi mohamed Mohammed Seaid Laboratory of Engineering Sciences Faculty of ScienceIbn Zohr UniversityAgadirMorocco School of Energy GeoscienceInfrastructure and SocietyHeriot-Watt UniversityEdinburghEH144ASUK Department of Engineering Durham UniversityDurhamDH13LEUK International Water Research Institute University Mohammed VI PolytechnicBenguerirMorocco

We propose a high-order enriched partition of unity finite element method for linear and nonlinear time-dependent diffusion *** solution of this class of problems often exhibits non-smooth features such as steep gradients and boundary layers which can be very challenging to recover using the conventional low-order finite element methods.A class of steady-state exponential functions has been widely used for enrichment and its performance to numerically solve these challenges has been ***,these enrichment functions have been used only in context of the standard h-version refinement or the so-called q-version *** this paper we demonstrate that the p-version refinement can also be a very attractive option in terms of the efficiency and the accuracy in the enriched partition of unity finite element ***,the transient diffusion problem is integrated in time using a semi-implicit scheme and the semi-discrete problem is then integrated in space using the p-version enriched finite *** results are presented for three test examples of timedependent diffusion problems in both homogeneous and heterogeneous *** computed results show the significant improvement when using the p-version refined enriched approximations in the finite element *** addition,these results support our expectations for a robust and high-order accurate enriched partition of unity finite element method.

关键词： Partition of unity finite element method p-version refinement

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The Effects of Gamma Irradiation on Molecular Weight, Morphology and Physical Properties of PHBV/Cloisite 30B Bionanocomposites

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Journal of Renewable Materials 2019年第9期7卷 807-820页

作者： Kahina Iggui mustapha Kaci mohamed Mahlous Nicolas Le Moigne Anne Bergeret Laboratoire des Matériaux Polymères Avancés(LMPA) Universitéde Bejaia06000 BejaiaAlgeria Institut de Technologie UniversitéAkli Mohand OulhadjBouira 10000Algeria Centre de Recherche Nucléaire d'Alger(CRNA) Boulevard Frantz FanonAlger 16000Algeria Centre des Matériaux des Mines d’Alès(C2MA)a IMT Mines AlèsUniversitéde Montpellier6 avenue de Clavières30319 Alès CedexFrance.

In this paper,the effects of gamma irradiation on Cast poly(3-hydroxybutyrate-co-3-hydroxyvalerate)(PHBV)and PHBV/Cloisite 30B(C30B)(3 wt%)bionanocomposite prepared by melt compounding,were evaluated at various doses,i.e.,5,15,20,50 and 100 kGy at room temperature in *** in molecular weight,morphology and physical properties were *** study showed that the main degradation mechanism occurring in gamma irradiation in both Cast PHBV and C-PHBV/3C30B bionanocomposite is chain scission,responsible for the decrease of molecular *** scanning calorimetry(DSC)data indicated a regular decrease in crystallization temperature,melting temperature and crystallinity index for all irradiated samples with increasing the ***,DSC thermograms of both Cast PHBV and PHBV bionanocomposite exhibited double melting peaks due probably to changes in the PHBV crystal *** and DMA data showed a reduction in Young’s modulus,strength,elongation at break and storage modulus with the radiation dose;the decrease was however more pronounced for Cast *** morphological damages were much less pronounced for the PHBV bionanocomposite sample compared to Cast PHBV,for which some irregularities and defects were observed at 100 *** study highlighted the ability of C30B to counterbalance the detrimental effect of radiolytic degradation on the functional properties of PHBV up to 100 kGy,thus acting as a potential anti-rad.

关键词： Poly(3-hydroxybutyrate-co-3-hydroxyvalerate)(PHBV) bionano-composite cloisite 30B gamma irradiation degradation

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Versatile synthesis of cadalene and iso-cadalene from himachalene mixtures:Evidence and application of unprecedented rearrangements

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Chinese Chemical Letters 2020年第7期31卷 1851-1854页

作者： mustapha Ait El Had Abdelouahd Oukhrib mohamed Zaki Martine Urrutigoity Ahmed Benharref Remi Chauvin Laboratoire de Chimie Biomoleculaire Substances Naturelies et Reactivite(URAC 16)Faculte des Sciences SemlaliaUniversite Cadi AyyadB.P.2390MarrakechMorocco CNRS LCC(Laboratoire de Chimie de Coordination)BP 4409931077Toulouse Cedex 4France INP-ENSIACET 4 allee Emile Monso31030Toulouse CedexFrance Universite de Toulouse UPSICT-FR 259931062Toulouse Cedex 9France

From a mixture of α-,β-and y-himachalenes extracted from waste wood of Atlas cedar(Cedrus atlantica),cadalene(1,6-dimethyl-4-isopropylnaphthalene)and iso-cadalene(1,6-dimethyl-3-isopropylnaphthalene)were produced in two steps with up to 71%±5%yield through the ar-himachalene intermediate using I2 and/or AlCl3 as *** selectivity is shown to sharply depend on the operating conditions:while I2/AlCl3 in dichloromethane promotes the formation of cadalene,the formation of iso-cadalene is favored in the presence of AlCl3 in *** bicyclic aromatic compounds were thus obtained through unique rearrangements involving sequential C—C bond cleavage/fo rmation and hydride transfer *** the absence of AlCl3 or I2,dihydrocurcumene was also found to be formed with up to 70%selectivity.A tentative mechanism is proposed and discussed.

关键词： Aromatic reactivity Cadalenes Dihydrocurcumene Himachalenes Rearrangements

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On an Axiomatic about Functional Means

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Analysis in Theory and Applications 2018年第1期34卷 36-44页

作者： mustapha Raissouli mohamed Chergui Abdellah Alla Department of Mathematics Science Faculty Taibah University AI Madinah AI Munawwarah P.O.Box 30097 Zip Code 41477 Saudi Arabia Department of Mathematics Science Faculty Moulay Ismail University Meknes Morocco Department of Mathematics LaREAMA Lab Centre Regional des Metiers de l'Education et de la Formation (CRMEF) Kenitra Morocco Department of Mathematics Mohammed V University Faculty of Sciences LAMA-ANLIMAD Rabat Morocco

In this paper, we introduce an axiomatic approach about functional means. This includes that of operator means already introduced in the literature.

关键词： Functional mean operator mean convex function.

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Contribution of phytoecological data to spatialize soil erosion:Application of the RUSLE model in the Algerian atlas

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International Soil and Water Conservation Research 2021年第4期9卷 502-519页

作者： Lynda Boussadia-Omari Sylvain Ouillon Aziz Hirche mustapha Salamani mohamed Said Guettouche Akli Ihaddaden Dalila Nedjraoui University of Science and Technology Houari Boumediene(USTHB) Faculty of BiologyLaboratory of Plant Ecology and Environment(EVE)BPN°32 El AliaBab EzzouarAlgerAlgeria LEGOS IRDCNRSCNESUPSUniversity of ToulouseToulouseFrance University of Science and Technology of Hanoi(USTH) Vietnam Academy of Science and Technology(VAST)HanoiViet Nam University of Science and Technology Houari Boumediene Faculty of Earth SciencesGeography and Spatial PlanningLaboratory of Geomorphology and Georisk(G&G)AlgerAlgeria

Among the models used to assess water erosion,the RUSLE model is commonly *** makers can act on cover(C-factor)and conservation practice(P-factor)to reduce erosion,with less costly action on soil surface ***,the widespread use of vegetation indices such as NDVI does not allow for a proper assessment of the C-factor in drylands where stones,crusted surfaces and litter strongly influence soil *** sub-factors of C,canopy cover(CC)and soil cover(SC),can be assessed from phytoecological measurements that include gravel-pebbles cover,physical mulch,annual and perennial *** paper introduces a method to calculate the C-factor from phytoecological data and,in combination with remote sensing and a geographic information system(GIS),to map it over large areas.A supervised classification,based on field phytoecological data,is applied to radiometric data from Landsat-8/OLI satellite ***,a C-factor value,whose SC and CC subfactors are directly derived from the phytoecological measurements,is assigned to each land cover *** method and RUSLE are implemented on a pilot region of 3828 km^(2) of the Saharan Atlas,composed of rangelands and steppe formations,and intended to become an *** protective effect against erosion by gravel-pebbles(50%)is more than twice that of vegetation(23%).The C-factor derived from NDVI(0.67)is higher and more evenly distributed than that combining these two contributions(0.37 on average).Finally,priorities are proposed to decision-makers by crossing the synthetic map of erosion sensitivity and a decision matrix of management priorities.

关键词： Water erosion Vulnerability Remote sensing Land-use mapping Aridity Soil protection Algerian atlas

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Effects of the hydro-ethanolic extract of Marrubium vulgare in female rats

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Asian Pacific Journal of Tropical Medicine 2017年第2期10卷 154-158页

作者： Rim Aouni Mossadok Ben Attia mohamed Habib Jaafoura Amina Bibi-Derbel mustapha Haouari Faculty of Sciences of Bizerte Department of life Sciences7021 JarzounaUniversity of Carthage INNTA SURVEN Research Laboratory(Monitoring and nutritional epidemiology in Tunisia) Laboratoire Biomonitoring of the Environment Faculty of Sciences of Bizerte.7021 JarzounaUniversity of Carthage Orthopedic Institutemohamed Kassab Laboratory of Cyto-Morphology and Anatomy Pathologic National Institute of Nutrition and Food technology Clinical laboratory of biochemistry Ecole Superior of Science and Technology of Health of Tunis University of Tunis El Manar

Objective:To evaluate the effects of ethanol–water(80:20) extract of Marrubium vulgare(***) on the hematological parameters,macroscopic and histological aspects of the uterus and fetus in non-pregnant and pregnant ***:Female rats were divided into 4 equal groups(n = 9),group N(normal rats) and group G(pregnant rats) considered as control groups,group NE(normal rats treated with the ethanol–water(80:20,v/v) extract of ***) and group GE(pregnant rats treated with the extract).The ethanol–water(80:20) plant extract was administered in a single daily dose 1 g/kg at the morning,during 19 *** the 19 day of the experiment,animals were sacrificed,the uterus and fetuses were removed for the morphological and histological studies and the blood was collected in EDTA tubes for the measurement of hematological parameters with the use of an automate ‘HORIBA ABX Micros 60 Hematology Analyzer'.Results:Our results showed,in group NE and GE,a significant decrease on hematological parameters:red blood cells(NE:18.6%;GE:38.4%),hematocrit(NE:13.8%;GE:20.4%),hemoglobin(NE:12.1%;GE:8.3%) and mean corpuscular volume(NE:6.4%;GE:2%) with P more less a ***,the extract of *** caused a significant decrease on the mean implantations of fetuses(82.5%,P<0.001) and their size(47.2%,P< 0.01).As for the macroscopic and histological appearance of uterus,our data showed no change in normal treated *** contrast,the treated pregnant rats showed a severe histological change characterized by the existence of location of stopped ***,it was also found in the uterus of these rat lyses placental and embryo ***:All these results support the hypothesis of an abortifacient effect of ***.

关键词： Vegetal extract Abortificiant effect Hematological parameters Fetuses Uterus Histology

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