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Toxicology Communications 2022年第2期4卷 23-28页

作者： Siddig Ibrahim Abdelwahab Abdullah Farasani Ahmed Jerah manal mohamed elhassan Taha Anil Bidwai medical Research Centre Jazan UniversityJazan 45142Saudi Arabia College of Applied medical Sciences Jazan UniversityJazan 45142Kingdom of Saudi Arabia Substance Abuse Research Center Jazan UniversityJazan 45142Saudi Arabia

Interaction of amphetamine,cathine and cathinone with the enzyme dihydrofolate reductase was studied by molecular docking using AutoDock 4.2 as the docking software *** 4.2 software serves as a valid and acceptable docking application to study the interactions of small compounds with *** of amphetamine,cathine and cathinone with dihydrofolate reductase were compared to those of methotrexate,a known inhibitor of the *** calculated free energy of binding(ΔG binding)shows that the three ligands(ΔG=-6.87 to-7.21 kcal/mol;Ki=9.15 to 5.18μm)bind with affinity slightly lower than methotrexate(ΔG=-8.78 kcal/mol;Ki=363 nm).Binding interactions of the three ligands with active site residues of the enzyme are also *** the ligands appear to bind in a similar conformation making extensive VDW contacts in the active site of the *** bonding and pi-pi interaction with key active site residues is also ***,a probable inhibition of dihydrofolate reductase by khat alkaloids can be explained on the basis of this in silico binding and khat alkaloids can be considered as potential lead compounds in the development of new inhibitors of dihydrofolate reductase which is a potential target of anti-cancer *** results of these studies can serve as a starting point for further computational and experimental studies.

关键词： amphetamine cathine cathinone methotrexate docking AutoDock DHFR khat alkaloids

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坚强芽孢杆菌——鳞翅目害虫新的病原菌

微生物学杂志 1988年第2期 64-64页

作者： R.V.Varma m.I.mohamed AIi 张敏鹰印度Kerala森林研究所昆虫病理学研究室印度Kerala森林研究所昆虫病理学研究室

Ailanthus tryphysa是一种软木树,它生长在印度南部的人造林中,这种树上有两种主要害虫:臭椿皮蛾(EIigma narcissus鳞翅目,夜蛾科)。和乔椿巢蛾(Atteva fabriciella鳞翅目,巢蛾科)1983年9—12月间,当这个地区的害虫大。量集聚时,发现有... 详细信息

Ailanthus tryphysa是一种软木树,它生长在印度南部的人造林中,这种树上有两种主要害虫:臭椿皮蛾(EIigma narcissus鳞翅目,夜蛾科)。和乔椿巢蛾(Atteva fabriciella鳞翅目,巢蛾科)1983年9—12月间,当这个地区的害虫大。量集聚时,发现有许多***死幼虫挂在树叶上,感染幼虫的肠溶物和分泌物中都有一种杆状菌。我们怀疑这些幼虫是受该菌寄生而死,为了证实这种可能

关键词：芽抱杆菌病原菌鳞翅目幼虫害虫

Evaluation of blended internet and face-to-face continuous medical education for cupping providers in Saudi Arabia

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TmR Non-Drug Therapy 2021年第1期4卷 28-35页

作者： Abdullah A.Al-mudaiheem Nasser A.Al-Hamdan Abdullah AlBedah Saud Al Sanad Tamer S.Aboushanab Ahmed T.elolemy mohamed K.m.Khalil National Center for Complementary and Alternative medicine Ministry of HealthRiyadhSaudi Arabia Faculty of medicine King Fahad Medical CityRiyadhSaudi Arabia College of medicine Al-Imam Mohammad Ibn Saud Islamic University(IMSIU)RiyadhSaudi Arabia Faculty of medicine Tanta UniversityTantaEgypt

Background:In regulating cupping therapy in Saudi Arabia,there was a need to develop a system for continuous medical and professional development for cupping *** current study aimed to evaluate the effect of blended-internet continuing-medical-education(CmE)on knowledge,knowledge retention,and intellectual skills in cupping providers compared with conventional,face-to-face ***:Participants were recruited from a list of registered cupping providers(physicians,nurses,and physiotherapists trained and licensed to practice cupping therapy)for a randomized,open,controlled *** providing informed consent,participants were allocated into three groups(classes).Classes were randomized to(1)blended-internet CmE(n=31);(2)conventional,face-to-face CmE(n=31);and(3)control group receiving no intervention(n=32).Results:Posttest knowledge scores were increased to a greater extent by blended-internet CmE training compared to conventional CmE(P=0.002)or no training(Pmilarly,knowledge retention was significantly higher in the blended-internet CmE group compared to the conventional CmE group(P=0.011).Posttest skills scores immediately after the course were significantly higher in the blended-internet CmE group compared to the conventional CmE group(mean difference:1.408,95%confidence interval:0.728–2.088,Pmed to determine if blended-internet CmE is as effective as conventional,face-to-face CmE,the results showed that cupping providers who participated in blended-internet CmE had significantly higher scores for posttest knowledge,knowledge retention,and posttest intellectual skills.

关键词： Cupping therapy Complementary medicine Education Internet Saudi Arabia

响应面法优化碱催化亮斑扁角水虻幼虫虫脂制备生物柴油工艺

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中国油脂 2023年第4期48卷 69-74页

作者：彭乔烽张栋马小梅刘高强丁功涛周雪雁皮尔·穆罕默德·阿卜杜勒西北民族大学中国-马来西亚国家联合实验室兰州730030 西北民族大学生命科学与工程学院兰州730030 西北民族大学生物医学研究中心兰州730030 马来西亚国立大学工程与建筑环境学院马来西亚雪兰莪州万宜43600

为实现亮斑扁角水虻幼虫(Black soldier fly larvae, BSFL)虫脂能源化利用,采用石油醚提取BSFL虫脂,通过碱催化BSFL虫脂甲酯化制备生物柴油。在单因素试验的基础上,利用响应面试验设计优化BSFL虫脂合成生物柴油的工艺条件;使用气质联用... 详细信息

为实现亮斑扁角水虻幼虫(Black soldier fly larvae, BSFL)虫脂能源化利用,采用石油醚提取BSFL虫脂,通过碱催化BSFL虫脂甲酯化制备生物柴油。在单因素试验的基础上,利用响应面试验设计优化BSFL虫脂合成生物柴油的工艺条件;使用气质联用仪分析生物柴油的脂肪酸组成,并评价生物柴油性能。结果表明:BSFL虫脂合成生物柴油的最优工艺条件为醇油体积比7.2∶1、反应时间2.0 h、KOH添加量为反应体系总质量的1.0%,在此条件下生物柴油产率达93.7%;生物柴油主要脂肪酸组分及含量为C12∶0 12.8%、C14∶0 3.8%、C16∶0 16.2%、C16∶1 1.9%、C18∶0 4.4%、C18∶1 24.2%、C18∶2 26.8%、C18∶3 4.1%;生物柴油运动黏度(40℃) 3.842 5 mm^(2)/s、运动黏度(25℃) 5.311 mm^(2)/s、动力黏度(25℃) 4.640 mPa·s、密度(25℃) 874 kg/m^(3)、密度(15℃) 879 kg/m^(3)、酸值(KOH) 0.12 mg/g、硫含量26 mg/kg、开口闪点160℃、闭口闪点142℃、残炭小于0.10%。碱催化BSFL虫脂甲酯化制备生物柴油的C14~C18含量较高,性能较好。

关键词：亮斑扁角水虻幼虫虫脂生物柴油甲酯化响应面法优化

Gastric Atrophy, Intestinal metaplasia in Helicobacter pylori Gastritis: Prevalence and Predictors Factors

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Journal of Biosciences and medicines 2016年第10期4卷 43-49页

作者： S. Adadi B. Bennani m. elabkari A. Ibrahimi S. Alaoui m. elkhadir T. Harmouch m. mahmoud C. Nejjari D. Benajah Service of Hepatology and Gastroenterology Hassan II University Hospital of Fez University Sidi Mohamed Ben Abdellah Fez Morocco microbiology and molecular Biology Laboratory Hassan II University Hospital of Fez University Sidi Mohamed Ben Abdellah Fez Morocco Service of Pathology Hassan II University Hospital of Fez University Sidi Mohamed Ben Abdellah Fez Morocco Service of Biology Hassan II University Hospital of Fez University Sidi Mohamed Ben Abdellah Fez Morocco Service of épidémiology Hassan II University Hospital of Fez University Sidi Mohamed Ben Abdellah Fez Morocco

Gastric atrophy and intestinal metaplasia represent the most important premalignant lesions in gastric carcinogenesis. The severity of gastric mucosal inflammation depends on the bacterium Helicobacter pylori (HP), on the host and on environmental factors. The aim of our study is to determine the prevalence and factors associated with Gastric atrophy and intestinal metaplasia in patients infected with Helicobacter pylori. methods: This is a prospective study over a period of 4 years (may 2009 - January 2015) conducted in the service of Hepatology and Gastroenterology in hospital university Hassan II of Fez in collaboration with microbiology and molecular biology laboratory and epidemiology service of Faculty of medicine and Pharmacy Fes. We included in our study all patients aged over 15 years, having ulcerative dyspepsia, peptic ulcer disease, gastritis or esophagitis. Results: During the study period, 1190 patients were included of which 70% had HP infection (N = 833). The average age was 48.21 years [16 - 99 years], sex ratio m/F was 1, 11. 60% of patients were older than 45 years. Chronic smoking was found in 12% of patients. Gastric atrophy was observed in 84% (N = 699) of patients infected with HP. Gastric atrophy was localized in 70% in the antrum and 30% in the fundus and 24% in both. The activity of gastritis (p = 0.0001) and the density of the HP (p = 0.005) were factors associated with atrophy. Intestinal metaplasia was observed in 13.5% of patients (N = 112). The density of HP (p = 0.037) and severe atrophy (p = 0.001) were factors associated with metaplasia. Other factors studied: age, sex, smoking, CagA+ genotype were not associated with either gastric atrophy or intestinal metaplasia. Conclusion: In our study, the prevalence of atrophic gastritis and intestinal metaplasia in patients infected with Helicobacter pylori was 84% and 13.5% respectively, which was a high prevalence. The activity of gastritis, and density of HP were factors associ

关键词： Gastric Atrophy Intestinal metaplasia Helicobacter pylori Gastritis

Families of Sordariomycetes

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Fungal Diversity 2016年第4期79卷 1-317页

作者： Sajeewa S.N.maharachchikumbura Kevin D.Hyde E.B.Gareth Jones E.H.C.mcKenzie Jayarama D.Bhat monika C.Dayarathne Shi-Ke Huang Chada Norphanphoun Indunil C.Senanayake Rekhani H.Perera Qiu-Ju Shang Yuanpin Xiao melvina J.D’souza Sinang Hongsanan Ruvishika S.Jayawardena Dinushani A.Daranagama Sirinapa Konta Ishani D.Goonasekara Wen-Ying Zhuang Rajesh Jeewon Alan J.L.Phillips mohamed A.Abdel-Wahab Abdullah m.Al-Sadi Ali H.Bahkali Saranyaphat Boonmee Nattawut Boonyuen Ratchadawan Cheewangkoon Asha J.Dissanayake Jichuan Kang Qi-Rui Li Jian Kui Liu Xing Zhong Liu Zuo-Yi Liu JJennifer Luangsa-ard Ka-Lai Pang Rungtiwa Phookamsak Itthayakorn Promputtha Satinee Suetrong marc Stadler Tingchi Wen Nalin N.Wijayawardene Guizhou Key Laboratory of Agricultural Biotechnology Guizhou Academy of Agricultural SciencesGuiyang 550006GuizhouChina Center of Excellence in Fungal Research and School of ScienceMae Fah Luang UniversityChiang Rai 57100Thailand Department of Crop Sciences College of Agricultural and Marine SciencesSultan Qaboos UniversityP.O.Box 34Al-Khod 123Oman Department of Botany and microbiology College of ScienceKing Saud UniversityP.O.Box 2455Riyadh 11451Kingdom of Saudi Arabia manaaki Whenua Landcare Research Private Bag 92170AucklandNew Zealand No.128/1-J Azad Housing SocietyCurcaP.O.Goa Velha403108 GoaIndia Department of Botany Goa UniversityGoa 403206India Engineering Research Center of Southwest Bio-Pharmaceutical Resources Ministry of EducationGuizhou UniversityGuiyang 550025Guizhou ProvinceChina Institute of Plant and Environment Protection Beijing Academy of Agriculture and Forestry SciencesNo 9 of ShuGuangHuaYuanZhangLuHaidian District Beijing 100097China State Key Laboratory of mycology Institute of MicrobiologyChinese Academy of SciencesBeijing 100101China Department of Health Sciences Faculty of ScienceUniversity of MauritiusReduitMauritius Faculty of Sciences Biosystems and Integrative Sciences Institute(BioISI)University of LisbonCampo Grande1749-016 LisbonPortugal Department of Botany Faculty of ScienceSohag UniversitySohagEgypt Fungal Biodiversity Laboratory BIOTECNational Science and Technology Development Agency(NSTDA)113 Thailand Science ParkThanon PhahonyothinTombon Khlong NuengAmphoe Khlong LuangPathum Thani 12120Thailand Department of Plant Pathology Faculty of AgricultureChiang Mai UniversityChiang Mai 50200Thailand Department of Pharmacy Guiyang Medical UniversityGuiyangGuizhou 550025China microbe Interaction Laboratory BIOTECNational Science and Technology Development Agency(NSTDA)113 Thailand Science ParkThanon PhahonyothinTombon Khlong NuengAmphoe Khlong LuangPathum Thani 12120Thailand Institute of marine Biology and Center of Excell

Sordariomycetes is one of the largest classes of Ascomycota that comprises a highly diverse range of fungi characterized mainly by perithecial ascomata and inoperculate unitunicate *** class includes many important plant pathogens,as well as endophytes,saprobes,epiphytes,coprophilous and fungicolous,lichenized or lichenicolous *** occur in terrestrial,freshwater and marine habitats *** paper reviews the 107 families of the class Sordariomycetes and provides a modified backbone tree based on phylogenetic analysis of four combined loci,with a maximum five representative taxa from each family,where *** paper brings together for the first time,since Barrs’1990 Prodromus,descriptions,notes on the history,and plates or illustrations of type or representative taxa of each family,a list of accepted genera,including asexual genera and a key to these taxa of *** of taxa is supported where possible by molecular *** outline is based on literature to the end of 2015 and the Sordariomycetes now comprises six subclasses,32 orders,105 families and 1331 *** family Obryzaceae and Pleurotremataceae are excluded from the class.

关键词： Amplistromatales Annulatascales Boliniales Calosphaeriales Chaetosphaeriales Coniochaetales Conioscyphales Cordanales Coronophorales Diaporthales Falcocladiales Glomerellales Hypocreales Jobellisiales Koralionastetales Lulworthiales magnaporthales melanosporales meliolales microascales Ophiostomatales Phylogeny Phyllachorales Pisorisporiales Pleurotheciales Sordariales Savoryellales Tirisporellales Togniniales Torpedosporales Trichosphaeriales Taxonomy Trichosphaeriales Type species Xylariales

Thermodynamic Analysis of Hydrocarbon Refrigerants-Based Ethylene BOG Re-liquefaction System

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Journal of marine Science and Application 2016年第3期15卷 321-330页

作者： Boumedienne m. Beladjine Ahmed Ouadha Yacine Addad Laboratoire des Sciences et Ingenierie maritimes Faculte de Genie Mecanique Universite des Sciences et de la Technologie Mohamed BOUDIAF d'Oran Oran E1-Mnouar 31000 Oran Algerie Khalifa University of Science Technology and Research P.O. Box 127788 Abu Dhabi UAE

The present study aims to make a thermodynamic analysis of an ethylene cascade re-liquefaction system that consists of the following two subsystems: a liquefaction cycle using ethylene as the working fluid and a refrigeration cycle operating with a hydrocarbon refrigerant. The hydrocarbon refrigerants considered are propane(R290), butane(R600), isobutane(R600a), and propylene(R1270). A computer program written in FORTRAN is developed to compute parameters for characteristic points of the cycles and the system's performance, which is determined and analyzed using numerical solutions for the refrigerant condensation temperature, temperature in tank, and temperature difference in the cascade condenser. Results show that R600 a gives the best performance, followed by(in order) R600, R290, and R1270. Furthermore, it is found that an increase in tank temperature improves system performance but that an increase in refrigerant condensation temperature causes deterioration. In addition, it is found that running the system at a low temperature difference in the cascade condenser is advantageous.

关键词： ethylene BOG re-liquefaction thermodynamic analysis hydrocarbon refrigerants

臭椿树上鳞翅目害虫的一种新病原——坚硬芽孢杆菌

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林业科技通讯 1987年第6期 34-34页

作者： R.V.VARmA ,m.I.mohamed ALI ,戴连韵

在印度南部的臭椿树上有两种引人瞩目的鳞翅目害虫臭椿皮蛾和乔椿巢蛾。1983年9月至12月,此地蔓延一种疫病,使很多臭椿皮蛾致死。死虫悬挂于树叶上。从感病幼虫的肠道内含物和渗出物中,相继发现一种杆状细菌,为确定此种细菌的致病性,进... 详细信息

在印度南部的臭椿树上有两种引人瞩目的鳞翅目害虫臭椿皮蛾和乔椿巢蛾。1983年9月至12月,此地蔓延一种疫病,使很多臭椿皮蛾致死。死虫悬挂于树叶上。从感病幼虫的肠道内含物和渗出物中,相继发现一种杆状细菌,为确定此种细菌的致病性,进行了试验研究。将在营养琼脂培养基上生长48—72小时的细菌培养物,悬浮在无菌蒸馏水中,制备成悬浮液。用1×1010CFU/ml 活细胞数在420毫微米处给出10D 值的吸收率来标定该悬浮液。接种试验材料为不同龄期的健康幼虫。用一个经灭菌的无菌喷雾器,把细菌悬浮液喷在臭椿叶上或用刷子把菌液刷在叶片上,然后将10条幼

关键词：芽抱杆菌臭椿树臭椿皮蛾鳞翅目害虫

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抑郁症的非药物治疗：系统性综述与证据图

英国医学杂志中文版 2017年第11期20卷 660-667页

作者： Wigdan H Farah mouaz Alsawas maria mainou Fares Alahdab magdoleen H Farah Ahmed T Ahmed Essa A mohamed Jehad Almasri michael R Gionfriddo Ana Castaneda-Guarderas Khaled mohammed Zhen Wang Noor Asi Craig N Sawchuk mark D Williams Larry J Prokop m Hassan murad Annie LeBlanc Evidence-Based Przctiee Center Mayo Clinic Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery Mayo Clinic Rochester Minnesota USA Knowledge and Evaluation Research Unit Mayo Clinic Rochester Minnesota USA Division of Preventive. Occupational and Aerospace medicine mayo Clinic Rochester Minnesota USA Integrated Behavioral Health Departmenl of Psychiatry and Psychology Mayo Clinic Rochester Minnesota USA mayo GraduateSchool Mayo ClinicRochesterMinnesota USA Center for PharmacyInnovation and Outcomes Geislnger Health System Forty Fort PennsylvaniaUSA Department of Emergency medicine Mayo ClinicRochesterMinnesota USA mayo Clinic

背景抑郁症非药物治疗的疗效比较目前仍然不清楚。方法我们对一些系统性综述作了概述，回顾了随机对照试验（RCT），比较抑郁症非药物治疗的有效性和认知行为治疗（CBT）。对多个电子数据库在2016年2月之前发表的所有文献进行了检索，... 详细信息

背景抑郁症非药物治疗的疗效比较目前仍然不清楚。方法我们对一些系统性综述作了概述，回顾了随机对照试验（RCT），比较抑郁症非药物治疗的有效性和认知行为治疗（CBT）。对多个电子数据库在2016年2月之前发表的所有文献进行了检索，不限制语言。成对的评阅人进行资料纳入、数据提炼并评估偏倚的风险。在适用的时候进行了荟萃分析。结果我们收录了367项RCT，纳入了约2000名患者，进行了11种治疗，导出17项独立的头对头比较。通过标准化的量表评估，发现CBT、自然疗法、行为干预与躯体活动干预可以降低抑郁的严重程度。然而，这些非药物干预的相对疗效仍然缺乏。这些干预对临床缓解和复发的效果不清楚。CBT的发生率比抗抑郁药物更低。局限性由于证据缺乏一致性、证据不清或偏倚风险高，导致证据的质量只是低到中等，限制了我们研究结果的可信度。结论抑郁症的非药物治疗能减少抑郁症状，在轻度到重度抑郁症患者中，应当合并抗抑郁药物治疗，一同进行。对于非药物治疗的选择，应当根据患者的价值观、偏好、临床和社会因素来与患者共同作出决定。

关键词：抑郁症非药物治疗系统性综述证据图

一种装有水利能源回收设备的小型反渗透脱盐系统的技术性能和有效性能的试验性比较研究

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水处理信息报导 2007年第3期 34-34页

作者： mohamed,Essam Sh. Agricultural University of Athens Greece

本文提供了一种具有1．7^3／d可饮用水生产能力的小型常用海水反渗透（SWRO）系统，通过安装一种水力能源回收设备且完全改变泵使该系统得到改良。在试验中测得的被建议使用系统的比能量消耗为3．3kWh／m^3，与常用系统20kWh／m^3相比... 详细信息

本文提供了一种具有1．7^3／d可饮用水生产能力的小型常用海水反渗透（SWRO）系统，通过安装一种水力能源回收设备且完全改变泵使该系统得到改良。在试验中测得的被建议使用系统的比能量消耗为3．3kWh／m^3，与常用系统20kWh／m^3相比是一个理想值。降低比能量消耗导致整个系统装机能量的降低，进而使透过产品成本降低。这种改良的目的是测试、

关键词：脱盐系统回收设备水力能源试验性反渗透有效性能技术性能水利