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Advances in Applied Mathematics and Mechanics 2021年第1期13卷 119-139页

作者： mohamed kara Salim Mesbahi Philippe Angot Applied Mathematics Laboratory Department of MathematicsFaculty of SciencesFerhat Abbas UniversitySetifAlgeria Fundamental and Numerical Mathematics Laboratory Department of MathematicsFaculty of SciencesFerhat Abbas UniversitySetifAlgeria Aix-Marseille Universit´e Institut de Math´ematiques de MarseilleCNRS UMR 7373MarseilleFrance

In framework of the fictitious domain methods with immersed interfaces for the elasticity problem,the present contribution is to study and numerically validate the jump-integrated boundary conditions method with sharp interface for the vector elasticity system discretized by a proposed finite volume *** main idea of the fictitious domain approach consists in embedding the original domain of study into a geometrically larger and simpler one called the fictitious ***,we present a cell-centered finite volume method to discretize the fictitious domain *** proposed method is numerically validated for different test *** work can be considered as a first step before more challenging problems such as fluid-structure interactions or moving interface problems.

关键词： Fictitious domain method sharp interface elasticity system jump embedded boundary conditions finite volume method

Valorization of a Good Bioceramic from Moroccan Waste Fish Bone by a Heat Treatment Method

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Journal of Renewable Materials 2019年第1期7卷 1-7页

作者： Kaoutar kara Fatiha Ouanji El Mostapha LOTFI Mohammed El Mahi mohamed Kacimi Laboratory of Spectroscopy Molecular ModelingMaterialsNanomaterialsWater and EnvironmentEnvironmental Materials TeamENSETMohammed V UniversityRabatMorocco Laboratory of Nanomaterial Nanotechnology and EnvironmentPhysico-chemical of Material and Catalysis(URAC26)Faculty of SciencesUniversity of Mohammed VRabat.Morocco

A tricalcium phosphate(TCP)material was produced from sardine and mackerel waste using a heat treatment method after a Soxhlet extraction to obtain the non-soluble portion of fish *** bones were annealed at temperatures between 400℃ and 1200℃.The thermal analysis(TG-DTA)was carried out to investigate the thermal stability of TCP and to confirm the removal of organic matter from the raw *** calcined bones were characterized by Fourier transform infrared spectroscopy(FT-IR),X-ray diffraction(XRD),and field emission scanning electron microscopy(FESEM).The calcium to phosphorous weight ratio was determined by ***-IR and XRD confirmed the similarities to syntheticβ-TCP(JCPDS-09-169),FE-SEM results revealed the formation of nanostructured *** results suggest that varying the isolation temperature between 600-1200℃ has tremendous impact on the production of TCP from fish bone waste with the required properties.

关键词： Hydroxyapatite tri-calcium phosphate fish bone heat treatement bioceramic

Assessment of Oral Anticoagulation with Vitamin K Antagonists in Patients Living in a Low-Income Country of West Africa

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World Journal of Cardiovascular Diseases 2024年第1期14卷 27-42页

作者： Komlavi Yayehd Tchaa Tcherou Hervé Libérus A. Edorh Agossou Defodji mohamed Kpelafia Ekpé Togbossi Ablawa Adzodo Soulemane Pessinaba Machihude Pio Soodogoua Baragou Findibe Damorou Department of Cardiology Faculty of Health Sciences University of Lomé Lomé Togo Department of Cardiology Faculty of Health Sciences University of Kara Kara Togo

Introduction: Despite the rise of direct oral anticoagulants (DOACs), vitamin K antagonists (VKA) remain the most widely used oral anticoagulants in developing countries. The aim of this study was to estimate the prevalence of good anticoagulation in patients treated with VKA in Lomé and describe associated factors. Methods: This was a cross-sectional study conducted from November 2019 to October 2020 in the cardiology departments of two University teaching hospitals in Lomé (CHU Sylvanus Olympio and CHU Campus), involving patients on VKA for ≥3 months, with a target international normalized ratio (INR) of 2.5 and a therapeutic margin between 2 and 3. The quality of anticoagulation was assessed by the time in therapeutic range (TTR) which was assessed by the Rosendaal method. Good anticoagulation was defined by a TTR > 70%. Results: A total of 344 patients were included (mean age = 58 ± 13.8 years, women = 56.1%). Indications for VKA treatment were represented by venous thromboembolic disease (43.3%), supraventricular arrhythmia (28.2%), severe left ventricular systolic dysfunction (19.8%) and pulmonary hypertension (8.7%). The average TTR was 47.6 ± 20.8%. The rate of good anticoagulation was 17.7%. Factors associated with good anticoagulation were the use of fluindione vs acenocoumarol (OR = 11.17;95% CI: 3.2 - 39.6;p = 0.0002), concomitant low-dose aspirin (OR 4.44;95% CI: 1.4 - 13.9;p = 0.01) and INR monitoring exclusively by the patient himself (OR = 4.92;95% CI: 1.5 - 16.3;p = 0.008). The rate of thromboembolic and hemorrhagic complications was each 2.6% and was not correlated with the quality of anticoagulation. Quality of anticoagulation by VKAs was poor in our practice. Factors associated with good anticoagulation were the use of fluindione vs acenocoumarol, concomitant low-dose aspirin and monitoring of INR exclusively by the patient himself. Conclusion: The quality of oral anticoagulation by VKAs could be improved in our practice by the creation of antico

关键词： Vitamin K Antagonists Time in Therapeutic Range Lomé Togo

Associated Factors to Poor Blood Pressure Control in Hypertensives Followed Up at the Campus University Hospital of Lome (Togo)

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World Journal of Cardiovascular Diseases 2024年第6期14卷 374-380页

作者： Soulemane Pessinaba Yaovi Mignazonzon Afassinou Wiyao Dieudonné Kaziga Komlavi Yayehd Kolani Lamboni Sélim Bolarinwa mohamed Kpélafia Ekpe Togbossi Akpe Adzodo Machihude Pio Soodougoua Baragou Findibé Damorou Cardiology Department University Hospital of Campus Lome Togo Cardiology Department Sylvanus Olympio University Hospital Lome Togo Cardiology Department Kara University Hospital Kara Togo

Introduction: Hypertension is a real public health issue and its control is very difficult. We aim to determine the frequency of uncontrolled hypertension in hypertensive patients followed up as an outpatient at the campus university hospital of Lome (Togo) and to search for the associated factors. Methodology: The study was cross-sectional, descriptive and analytical, carried out from February (2022) to August 2022 in 260 hypertensive patients aged 22 years old, followed up (on an) as an outpatient for at least 3 months at the Lome University Hospital campus. A univariate then multivariate analysis were conducted in order to highlight the most common factors significantly linked to uncontrolled. Results: The mean age of hypertensives was 56.4 ± 12.7 years, the sex ratio (M/F) was 0.59. Prevalence of uncontrolled blood pressure was 42%. Associated Factors to poor blood pressure control in our study were age > 60 years (OR = 1.6 CI [1.17 - 2.50]), low socio-economic level (OR = 2.2 CI [1.96 - 4.33]), high cardiovascular risk level (OR = 3.1 CI [2.18 - 4.52]), non-adherence to regular blood pressure monitoring (OR = 3.3 CI [2.21 - 5.55]), low compliance to treatment (OR = 4.1 CI [2.33 - 6.76]) and a chronic renal failure (OR = 2.1 CI [1.21 - 3.10]). Conclusion: Nearly half of the hypertensives in our study had poorly controlled blood pressure by antihypertensive treatment medication. The factors of this poor control were age > 60 years, low socio-economic level, high or very high level of cardiovascular risk, low compliance to treatment, and renal failure.

关键词： Hypertension Poor Control Associated factors Togo

A Simple and Efficient Procedure for a 2-Pyridones Synthesis under Solvent-Free Conditions

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International Journal of Organic Chemistry 2011年第4期1卷 242-249页

作者： Zahira Kibou Nawel Cheikh Didier Villemin Noureddine Choukchou-Braham Bachir Mostefa-kara mohamed Benabdallah 不详

A new series of 3-cyano-2-pyridones derivatives have been prepared by reaction of enaminonitriles with pri-mary amine under solvent free condition. This procedure have the advantage of high yields and being environ-me... 详细信息

关键词： 2-Pyridones Solvent-Free Enaminonitriles Green Chemistry

COVID-19 Infection and Acute Kidney Injury: About 43 Cases Report Collected at the Nephrology Department of the Farah Polyclinic in Abidjan

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Open Journal of Nephrology 2022年第4期12卷 410-425页

作者： Badomta Dolaama Serge Didier Konan Sery Patrick Diopoh mohamed Alex Moudachirou Komlan Georges Tona Eyram Yoan Makafui Amekoudi Mawufemo Claude Tsevi Kouamé Hubert Yao Farah Polyclinic Abidjan Cote d’Ivoire Nephrology and Hemodialysis Department Teaching Hospital of Sylvanus Olympio Lome Togo Nephrology Department Teaching Hospital of Treichville Treichville Cote d’Ivoire Nephrology Department Teaching Hospital of Kara Lome Togo

Background: Acute kidney injury (AKI) is one of the increasingly described complications of coronavirus infection. Objectives: To identify factors associated with death in patients with acute kidney injury (AKI) during Coronavirus disease (COVID-19) in Abidjan, C?te d’Ivoire. Material and Method: This was a monocentric retrospective analytical study of all patients over 18 years of age with AKI during COVID-19 at the Farah Polyclinic in Abidjan, C?te d’Ivoire. AKI was defined and ranked according to Kidney Disease Improving Global Outcomes (KDIGO) 2012. The data were collected from the medical record and processed using RStudio. Results: Forty-three cases were collected. The average age was 58.5 12 years. The sex ratio (M/F) was 4.4. The main comorbidities were high blood pressure (60.4%) and diabetes (37.2%). AKI was at KDIGO stage 3 in 58%, KDIGO 2 in 21% and KDIGO 1 in 21%. The diagnosis of acute tubular necrosis was retained in 44.2% of patients followed by acute functional kidney injury in 32.6%. Hemodialysis was initiated in 48.8% of cases. The main indication of dialysis was anuria (46.6%). In total, 55.8% of patients died. Factors associated with death were KDIGO stage (p = 0.049), and invasive ventilation (p Conclusion: Mortality is high in patients with AKI during COVID-19 infection.

关键词： Coronavirus Acute Kidney Injury Abidjan 2020

Ventricular Non-Compaction: About the First Cases Reported in Lomé(Togo)

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World Journal of Cardiovascular Diseases 2020年第12期10卷 775-783页

作者： Soodougoua Baragou Soulemane Pessinaba Tchalla Abéna Ekpé Togbossi Wiyaou Kaziga Komlavi Yayehd mohamed Kpélafia Nkenon Watani N’Da El Nassirine Oloudé Machihude Pio Findibe Damorou Cardiology Department Sylvanus Olympio Teaching Hospital Lomé Togo Cardiology Department Campus Teaching Hospital Lomé Togo Cardiology Department Tomde Hospital Kara Togo Cardiology Department Kara Teaching Hospital Kara Togo

Introduction: Ventricular non-compaction, a cardiomyopathy recently described as likely to be rare, belongs to the group of unclassified cardiomyopathy according to European Society of Cardiology. Few studies have been published on the ventricular non-compaction in sub-Saharan Africa. We aim to find out the various aspects, being diagnosis, therapeutic, in Togolese patients carrying the ventricular non-compaction. Methodology: This is a three-year prospective and descriptive study conducted from January 2017 to December 2019 in the two University Hospital of Lomé. Patients having echocardiographic criteria of ventricular non-compaction were included in our study. Results: 10 patients (6 men and 4 women) were diagnosed for ventricular non-compaction during the study period. The mean age of patients was 32.3 years. The most frequent clinical manifestation was heart failure (7 patients). The main electrocardiogram anomaly was left ventricle hypertrophy (9 patients). The preferential segments were: apical (9 cases), apicolateral (8 cases), and septoapical (7 cases). The average ratio of non-compaction/compaction was 3.31. The main complication was thromboembolic event (4 patients). Angiotensin converting enzyme inhibitors and beta-blockers were essentially the medicines used. After a three (3) year follow-up, two (2) of the patients died. Conclusion: Tough ventricular non-compaction has been recently described. It is present in Togo. It displays many clinical manifestations and the prognosis is often guarded.

关键词： Ventricular Non-Compaction Hypertrophy Sub-Saharan Africa Heart Failure Togo

Brugada Syndrome Type 1 Electrocardiogram Pattern Induced by Fever in a Black African: A Case Report

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World Journal of Cardiovascular Diseases 2020年第8期10卷 558-562页

作者： Soulemane Pessinaba Ekpé Togbossi Wiyaou Kaziga Baete Koudéma Pizeriwé Dossim Komlavi Yayehd mohamed Kpélafia Nkenon Watani N’Da Borgatia Atta Tchaa Tchérou Yaovi Afassinou Machihude Pio Soodougoua Baragou Adama Kane Findibe Damorou Cardiology Department Campus Teaching Hospital Lome Togo Cardiology Department Kara Teaching Hospital Kara Togo Cardiology Department Sylvanus Olympio Teaching Hospital Lome Togo Cardiology Department Saint-Louis Hospital Saint-Louis Senegal

Brugada syndrome is a channelopathy that can be familial or sporadic. It is a major cause of sudden death in young people with no obvious heart structural abnormality. The electrocardiogram can be dynamic over time with sometimes normalization. Several pathophysiological conditions are known to induce the electrocardiographic expression of the syndrome. We report here the case of a 65-year-old hypertensive man, without syncope or family sudden death history who was hospitalized for shigella gastroenteritis. Electrocardiogram during fever showed an incomplete block and ST segment elevation with negative T waves in V1 and V2 suggested type 1 Brugada syndrome. Troponin was negative. Electrocardiogram after fever recovered an incomplete right block and normalization of the ST segment. Electrocardiogram should be performed in patients admitted to the emergency unit for infectious syndrome in our countries. This may reveal a number of patients with Brugada syndrome abnormalities.

关键词： Brugada Syndrome Electrocardiogram Fever