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Analysing user daylight preferences in heritage buildings using virtual reality

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Building Simulation 2022年第9期15卷 1561-1576页

作者： mohamed Marzouk Maryam elsharkawy Ayman Mahmoud Department of Structural Engineering Faculty of EngineeringCairo University12613GizaEgypt Department of Architecture Engineering Faculty of EngineeringCairo University12613GizaEgypt

Technology has always been creating effective ways to support human *** virtual reality(IVR)has emerged to engage users in a simulated world,and this has gained the interest of a wide variety of users in the heritage industry.A historical case study built in the early 19th century is considered for an adaptive reuse *** palace is located in Cairo,Egypt,and named after Prince Omar *** current palace state incorporates a smashed top-lit zone,which is being studied and analyzed for daylighting *** simulated distinct optimum skylight configurations are suggested for the redesign where the selection should not be based solely on simulation data,but should consider real-user *** daylight design criteria are previously based on simulation data that do not necessarily indicate the users'*** utilizing user interactive tools such as IVR to test daylight redesign options,a whole new dimension is *** this study,the VR users’survey data is statistically analyzed using Statistical Package for Social Sciences(SPSS),where results revealed that the assessment attributes succeeded in reflecting the users'preferences;which,motivated designers to consider potential users’daylight preferences in reused *** paper highlights the most significant emotional attributes that provide cost-effective and reliable information concerned with the performance of daylight in IVR before design *** study compares and analyzes the effect of three skylight designs(Cases A,B&C)on the users'perception before design implementation using(IVR)***-eight participants have contributed to the study,providing their feedback on six attributes namely:Pleasant,Contrasting,Brightness,Uniform Distribution,Visual Comfort,and *** attributes are evaluated for the three cases in space using five scale rating values to reveal that the"Pleasant"attribute is most reliable in the study to reflect th

关键词： daylight preferences heritage buildings rehabilitation immersive virtual reality statistical analysis

Fibrosis regression following hepatitis C antiviral therapy

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World Journal of Hepatology 2022年第6期14卷 1120-1130页

作者： Aisha elsharkawy Reham Samir mohamed El-Kassas Department of Endemic Medicine and Hepatogastroenterology Faculty of MedicineCairo UniversityCairo 11566Egypt Department of Endemic Medicine Faculty of MedicineHelwan UniversityCairo 11795Egypt

Hepatitis C virus(HCV)infection is one of the most common causes of liver *** is a major etiological factor of continuous liver injury by triggering an uncontrolled inflammatory response,causing liver fibrosis and *** fibrosis is a dynamic process that can be reversible upon timely cessation of the injurious agent,which in cases of HCV is represented by the sustained virological response(SVR)following antiviral ***-acting antiviral therapy has recently revolutionized HCV therapy and minimized *** fibrosis can be assessed with variable invasive and non-invasive methods,with certain *** the broad validation of the diagnostic and prognostic value of non-invasive modalities of assessment of liver fibrosis in patients with HCV,the proper interpretation of liver stiffness measurement in patients after SVR remains *** is also still a debate whether this regression is caused by the resolution of liver injury following treatment of HCV,rather than true fibrosis *** of liver fibrosis can possess a positive impact on patient's quality of life reducing the incidence of ***,fibrosis regression does not abolish the risk of developing hepatocellular carcinoma,which mandates regular screening of patients with advanced fibrosis.

关键词： Fibrosis regression Hepatitis C virus Direct-acting antivirals Hepatocellular carcinoma Liver fibrosis Cirrhosis

Evaluation of GALAD Score in Diagnosis and Follow-up of Hepatocellular Carcinoma after Local Ablative Therapy

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Journal of Clinical and Translational Hepatology 2023年第2期11卷 334-340页

作者： Rasha Eletreby Marwa elsharkawy Alaa Awad Taha mohamed Hassany Amr Abdelazeem mohamed El-Kassas Ahmed Soliman Endemic Medicine Department Faculty of MedicineCairo UniversityCairoEgypt Clinical and Chemical Pathology Department Faculty of MedicineCairo UniversityCairoEgypt Hepatogastroenterology Department Theodore Bilharz Research InstituteGizaEgypt Hepatogastroenterology Department National Hepatology and Tropical Medicine Research InstituteCairoEgypt Endemic Medicine Department Faculty of MedicineHelwan UniversityCairoEgypt

Background and Aims:Strategies for detection of early hepatocellular carcinoma(HCC)are still *** GALAD score is a serum biomarker-based model designed to predict the probability of having *** aimed to assess the ability of GALAD score to diagnose early HCC and its validity to follow patients after local ablation ***:This multicenter prospective study included 108 patients in two groups,58 HCC patients(67 focal lesions)with local ablative therapy(study group),and a control group of 50 patients with liver *** GALAD scores of the study and control groups,and of the HCC patients before and after ablative therapy were ***:Most patients were men(74.1%in study group and 76%in controls)with hepatitis C virus infection(98.30%in the study group,and 94%in controls).GALAD scores were significantly higher in HCC patients than in those with benign cirrhosis(2.65 vs.−0.37,p=0.001).Ablative therapy was successful in 94.4%of focal lesions<2 cm,and in 86.10%of 2–5 cm *** GALAD score was also significantly lower at 1 month after ablation in patients with well-ablated tumors(2.19 vs.0.98,p=0.001).The best cutoff values of GALAD score for diagnosis of early HCC,and for prediction of well ablation of HCC were 0.74 and≤3.31(areas under the curve of 0.92 and 0.75,sensitivities of 84.48%and 76.19%,specificities of 89.13%and 83.33%,positive predictive values of 90.74%and 94.1%,and negative predictive values of 82%and 35.7%respectively).Conclusion:The GALAD score was effective for the diagnosis of early HCC and for followup after ablative therapy.

关键词： GALAD score HCC Ablative therapy Liver cirrhosis Egypt

GnRH-Agonist Trigger versus Human Chorionic Gonadotrophin (HCG) Trigger in Cases of Controlled Ovarian Stimulation;Randomized Controlled Trial

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Open Journal of Obstetrics and Gynecology 2021年第11期11卷 1452-1460页

作者： mohamed Elmahdy Suzan elsharkawy Department of Obstetrics and Gynecology Faculty of Medicine Alexandria University Alexandria Egypt

Objectives: The aim of the study was to compare the efficacy and safety of GnRH-agonist to the human chorionic gonadotrophin (HCG) trigger in cases of simple ovarian stimulation. Study design: Randomized controlled trial was conducted on 291 women complaining of unexplained infertility visiting Elshatby Maternity University Hospital from February to December 2019. Trial registration unique ID is PACTR202001787868341 (https://***/). Age included from 20 - 43 years. All patients were stimulated by the sequential stimulation protocol using letrozole then FSH injection, when the criteria of ovulation trigger were reached; cases were randomized into two groups using closed envelopes method.

关键词： GnRH Agonist HCG Ovulation Trigger OHSS

Anti-inflammatory and Chemical Composition of Two Plants Family Asteraceae Growing in Saudi Arabia

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Journal of Chemistry and Chemical Engineering 2014年第2期8卷 157-162页

作者： Eman elsharkawy Mona Alshathly mohamed Helal Plant Ecology and Range Department Desert Research Center Cairo 15753 Egypt Chemistry Department Northern Border University Afar 054 Saudi Arabia Zoology Department Northern Border University Arar 054 Saudi Arabia Chemistry Department Northern Border University RaJha 054 Saudi Arabia

The study was designed to investigate the anti-inflammatory and composition of essential oil of two plant family Asteraceae, Achillea fragrantissima and Lactuca serriola growing under dry desert condition. The anti-inflammatory effect of volatile oil extracted by hydrodistillation of plants was studied using carrageenan induced paw edema. Essential oil （100 mg/kg） and （200 mg/kg） were tested the two plant show high inhibition after 4 h, concentration （200 mg/kg） show high inhibition than （100 mg/kg） after 4 h. Sesqui sabinene hydrate, Azuline and u-Bisabolol are the main constituents of the volatile oil were investigated by capillary GC （gas chromatography） and GC-MS （gas chromatography-mass spectrometry）. The discussion shows the role of chemical compound azulene in inflammatory inhibition.

关键词： Achillea fragrantissima Lactuca serriola anti-inflammatory azulene.

Prediction and Modelling of Corrosion in Steel Storage Tank Using Non-destructive Inspection

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材料科学与工程（中英文B版） 2013年第12期3卷 785-792页

作者： Mosaad mohamed Sadawy Eltohamy Rabie elsharkawy Faculty of Engineering AI-Azhar University Cairo Egypt Nuclear & Radiological Regulatory Authority Cairo Egypt

Effect of Cumulus Cells on the Efficiency of Vitrified-Thawed Immature Cattle Oocytes

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Open Journal of Obstetrics and Gynecology 2019年第5期9卷 669-678页

作者： Samia mohamed Abd-El Rheem Suzan elsharkawy Theriogenology Department Faculty of Veterinary Medicine Alexandria University Alexandria Egypt Gynecology and Obstetrics Department Faculty of Medicine Alexandria University Alexandria Egypt

The present work was designed to examine the effect of the presence or absence of cumulus cells on the efficiency of vitrification of immature cattle oocytes. In our experiment, we had two groups: group 1, immature cattle oocytes with cumulus cells and group 2, immature cattle oocytes without cumulus cells. The two groups underwent vitrification using 20% ethylene glycol and 20% DMSO, and then thawed, and in vitro matured in TCM-199 medium and examined after 22 hours for assessment of nuclear maturation. Higher survival rate (p < 0.05) after thawing was observed in group 1 (84.6%) than group 2 (57.8%). After in-vitro maturation, the rate of MII oocytes was significantly higher (p < 0.05) in group 1 (74.4%) than group 2 (47.7%). In conclusion, the cumulus cells are very important in increasing the survivability and developmental rate of vitrified-thawed immature cattle oocytes.

关键词： Cumulus Cells Vitrified-Thawed Immature Oocytes Cattle

The Tumor Infiltrating Lymphocytes (TILs): Did We Find the Missed Piece of the Huge Puzzle?

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Open Journal of Obstetrics and Gynecology 2021年第2期11卷 146-161页

作者： Suzan Samir elsharkawy mohamed Abd Elrheem Samia Abd Elrheem Department of Obstetrics and Gynecology Faculty of Medicine Alexandria University Alexandria Egypt

Tumor infiltrating lymphocytes (TILs) are used in evaluating the prognosis and determining treatment of different types of cancer with variable degrees of success. The usage of checkpoint inhibitor immunotherapy as a treatment variety for cancer and Adoptive cell therapy is associated with many complications, severe side effects and high expenses. Recently, in a limited number of metastatic GIT and breast cancers, the identification of T-cell specific against so-called tumor neo-antigens and Adoptive transfer of those lymphocytes resulted in some improvement. In 2020, Detection of a T cell receptor (TCR) in a T cell clone that recognized and killed most human cancer cell lines in vitro via the monomorphic MHC class I-related protein MR1, offers an opportunity for pan-cancer therapy Twenty three years earlier, Moist Heat was used successfully to activate a whole different and new immune response that was able to detect genetic mutation in the affected cancer cells and cured many cases of squamous and basal cell carcinomas. In this commentary review, we aimed to revise the literature for updates of TILs usage in cancer prognosis and treatment.

关键词： Tumor Infiltrating Lymphocytes Cancer Checkpoint Inhibitor Adoptive Cell Therapy T Cell Receptor (TCR) Moist Heat Pan-Cancer Therapy Squamous Cell Carcinoma Basal Cell Carcinomas

Formation and Characterization of Zinc Phosphate Coating on Reinforcing Steel Rebars

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材料科学与工程（中英文A版） 2013年第7期3卷 481-487页

作者： Mosaad Mohamad Sadawy mohamed Taha Nooman Eltohamy Rabie elsharkawy Mining and Petroleum Engineering Department Faculty of Engineering Al-Azhar University Nasr City 11884 Cairo Egypt Civil Engineering Department Faculty of Engineering Al-Azhar University Nasr City 11884 Cairo Egypt Nuclear & Radiological Regulatory Authority. Cairo Egypt