检索结果-南通市图书馆

Anti-inflammatory and analgesic properties of Moroccan medicinal plants:Phytochemistry,in vitro and in vivo investigations,mechanism insights,clinical evidences and perspectives

引用

Journal of Pharmaceutical Analysis 2022年第1期12卷 35-57页

作者： Abdelhakim Bouyahya Fatima-Ezzahrae Guaouguaou Nasreddine el Omari Naoual el Menyiy Abdelaali Balahbib mohamed el-shazly Youssef Bakri Laboratory of Human Pathologies Biology Department of BiologyFaculty of Sciencesand Genomic Center of Human PathologiesFaculty of Medicine and PharmacyMohammed Ⅴ University in Rabat4014Morocco Mohammed Ⅴ University in Rabat LPCMIOMaterials Science Center(MSC)Ecole Normale SuperieureRabat1014Morocco Laboratory of Histology Embryology and CytogeneticFaculty of Medicine and PharmacyMohammed Ⅴ University in Rabat10100Morocco Department of Biology Faculty of Sciences Dhar El MahrazUniversity Sidi Mohamed Ben AbdellahFez30003Morocco Laboratory of Zoology and General Biology Faculty of SciencesMohammed Ⅴ University in RabatRabat1014Morocco Department of Pharmacognosy Faculty of PharmacyAin-Shams UniversityCairo11566Egypt Department of Pharmaceutical Biology Faculty of Pharmacy and BiotechnologyGerman University in CairoCairo11835Egypt

Moroccan medicinal plants exhibit several pharmacological properties such as antimicrobial,anticancer,antidiabetic,analgesic,and anti-inflammatory effects,which are related to the presence of numerous bioactive compounds,including phenolic acids,flavonoids,and *** the present review,we systematically evaluate previously published reports on the anti-inflammatory and analgesic effects of Moroccan medicinal *** in vitro investigations revealed that Moroccan medicinal plants inhibit several enzymes related to inflammatory processes,whereas in vivo studies noted significant anti-inflammatory and analgesic effects as demonstrated using different experimental *** bioactive compounds exhibiting in vitro and in vivo anti-inflammatory and analgesic effects,with diverse mechanisms of action,have been *** plants and their bioactive compounds reveal specific secondary metabolites that possess important anti-inflammatory effects in clinical *** review proposes the potential applications of Moroccan medicinal plants as sources of anti-inflammatory and analgesic agents.

关键词： Inflammation Medicinal plants Bioactive compounds Anti-inflammatory Analgesic

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Radiographic and magnetic resonances contrast agents:Essentials and tips for safe practices

引用

World Journal of Radiology 2017年第9期9卷 339-349页

作者： mohamed R Nouh mohamed A el-shazly Department of Radiology and Clinical Imaging Faculty of MedicineAlexandria UniversityAlexandria 21563Egypt

With extended and continued expansion of medical imaging utilization in modern medical practice over last decade, radiologists as well as other faculty staff dealing with radiographic and magnetic resonances contrast media(CM) have to be well oriented with their potential hypersensitivity reactions and recognize high-risk groups liable to develop it so as to enable early recognition. Radiologists and other medical staff involved in administration and dealing with CM have to be ready to implement prompt, practical and effective management plan to deal with these scenarios should they emerge. Strategies to prevent potential contrastinduced acute and delayed renal injuries have to be routinely exercised. Paying attention to the pregnant and nursing women, pediatrics, diabetics, as well as other fragile populations is of utmost importance for patient safety during contrast administrations. Radiologists should play a pivotal role in orienting patients about necessity to use CM for their imaging studies, in case it is needed, and assure them about its safety. Moreover, they have to be oriented with the medico-legal issues related to use of CM. These will pay as improved patient safety as well as safe daily working environmentat different levels of radiology practices.

关键词： Radiographic Magnetic resonances Contrast Safe practice Medico-legal

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Uncoupling tumor necrosis factor-αand interleukin-10 at tumor immune microenvironment of breast cancer through miR-17-5p/MALAT-1/H19 circuit

引用

BIOCelL 2022年第3期46卷 769-783页

作者： RAGHDA A.SOLIMAN RANA A.YOUNESS TAMER M.MANIE EMAD KHALLAF mohamed el-shazly MONA ABDelMOHSEN HEBA HANDOUSSA mohamed Z.GAD Pharmaceutical Biology Department Faculty of Pharmacy and BiotechnologyGerman University in CairoCairo11835Egypt School of Life and Medical Sciences University of Hertfordshire Hosted by Global Academic FoundationNew Administrative Capital11578Egypt Breast Surgery Department National Cancer InstituteCairo UniversityCairoEgypt General Surgery Department Faculty of MedicineCairo UniversityCairoEgypt Department of Phytochemistry National Research CentreGiza12622Egypt Biochemistry Department Faculty of Pharmacy and BiotechnologyGerman University in CairoCairo11835Egypt

Triple Negative Breast Cancer(TNBC)immunotherapy has recently shown promising ***,some TNBC patients presented with *** of the reasons was attributed to the excessive release of cytokines at the tumor microenvironment(TME)such as Tumor necrosis factor alpha(TNF-α)and Interleukin-10(IL-10).Fine regulation of these cytokines’levels via non-coding RNAs(ncRNAs)might alleviate the immune quiescent nature of TME at TNBC ***,the extrapolation of ncRNAs as therapeutic tools is highly ***,disentanglement the nature for the isolation of natural compounds that could modulate the ncRNAs and their respective targets is an applicable translational therapeutic ***,this study aimed to targeting the chief immune suppressive cytokines at the TME(TNF-αand IL-10)via ncRNAs and to examine the effects of Rosemary aerial parts extract on the expression levels of these ncRNAs in *** revealed miR-17-5p as a dual regulator of TNF-αand ***,an intricate interaction has been shown between miR-17-5p and the oncogenic lncRNAs:MALAT1 and *** down of MALAT1 and/or H19 caused an induction in miR-17-5p and reduction in TNF-αand IL-10 expression ***-17-5p was found to be down-regulated,while TNF-α,IL-10,MALAT1 and H19 were up-regulated in BC *** expression of miR-17-5p in MDA-MB-231 cells reduced TNF-α,IL-10,MALAT1 and H19 expression levels,as well as several BC *** a translational approach,ursolic acid(UA)isolated from rosemary induced the expression of miR-17-5p,MALAT1 and decreased H19 expression *** conclusion,this study suggests miR-17-5p as a tumor suppressor and an immune-activator miRNA in BC through tuning up the immunological targets TNF-α,IL-10 at the TME and the oncological mediators MALAT1 and H19 lncRNAs.

关键词： Breast cancer Tumor microenvironment Cytokines TNF-α IL-10 miR-17-5p MALAT1 H19 lncRNAs miRNA Ursolic acid

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Comparison between seismic analysis of twisting and regular 52-story towers considering soil-structure interaction

引用

Earthquake Engineering and Engineering Vibration 2024年第3期23卷 663-675页

作者： mohamed Naguib Abouelsaad Mohammed Shaaban Salah el Bagalaty mohamed E.el Madawy Structural Engineering Department Faculty of EngineeringMansura UniversityMansoura 35511Egypt Faculty of Engineering Delta University for Science and TechnologyGamasa 35712Egypt

A dynamic analysis of both twisting and regular towers is carried out to determine the results of considering soil-structure interaction(SSI)on high-rise *** addition,the difference between the seismic performance of using twisting towers over regular ones is *** twisting tower is a simulation of the Evolution Tower(Moscow).The towers’skeletons consist of RC elements and rest on a reinforced concrete piled-raft *** soil model is considered as multi-layered with the same soil properties as the zone chosen for the analysis(New Mansoura City,Egypt).The only difference between both towers is their shape in *** whole system is modelled and analyzed in a single step as one full 3D model,which is known as the direct approach in *** analyses are carried out using finite-element software(Midas GTS NX).Dynamic output responses due to three records of seismic loads are proposed and presented in some *** on the results,it is concluded that SSI has a considerable effect on the dynamic response of tall buildings mainly because of the foundation flexibility,as it leads to lengthening the vibration period,increasing the story drift and the base shear for both cases.

关键词： soil-structure interaction seismic analysis twisting towers base shear story drift finite element method Midas GTS NX

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Laryngopharengeal Reflux in Gastroesophageal Reflux Disease: Does “Silent Laryngopharengeal Reflux” Really Exist?

引用

Open Journal of Gastroenterology 2014年第3期4卷 130-140页

作者： Iman Ramzy mohamed el shazly Raghda Marzaban Tamer elbaz Mina Safwat Botros Latif Endemic Medicine and Hepatogastroenterology Faculty of Medcinie Cairo University Cairo Egypt Hepatogastroenterology Police Recruits Hospital Cairo Egypt Otorhinolaryngeology Faculty of Medicine Cairo University Cairo Egypt

Background: Gastroesophageal reflux disease (GERD) is a disorder resulting from the reversed flow of gastroduodenal contents into the esophagus, and producing different symptoms, while laryngopharyngeal reflux (LPR) is a disorder resulting from the reversed flow of gastric contents into the hypopharynx. The aim of this work is to evaluate LPR in cases of GERD. Methods: The present study was performed on fifty GERD patients diagnosed by gastroscope. LPR was assessed by reflux symptoms score (RSI) and reflux finding score (RFS). Accordingly, patients are classified into: Group I = 25 patients with manifest LPR, and Group II = 25 control patients without LPR symptoms. Results: GERD accounts for 17.4% of attendants of gastroscope unit, where manifest LPR accounts for 29.1% of GERD cases recording mean RSI and RFS 16.48 and 8.44 respectively. Silent LPR accounts for 8% recording mean RFS 7. Conclusion: There is a significant direct proportional relationship between severity of GERD and the RSI and RFS (p = 0.015 and 0.005 respectively).

关键词： Gastroesophageal Reflux Disease (GERD) Laryngopharyngeal Reflux (LPR) Reflux Symptoms Index (RSI) Reflux Finding Score (RFS)

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Optimized system for combined production of electricity/green hydrogen for multiple energy pathways:a case study of Egypt

引用

Clean Energy 2024年第4期8卷 219-236页

作者： Reda Ragab mohamed HamdiHafez A.el Salmawy mohamed A.Ismail Mechanical Power Engineering Department Zagazig UniversityZagazig 44519Egypt Mechanical Engineering Department College of EngineeringKing Faisal UniversityAl-Ahsa 31982Saudi Arabia

By optimal sizing of a wind/photovoltaic hybrid renewable-energy(RE)system,trimming the surplus capacity to reduce the fluctuations in the electricity supplied to the grid,and using it to produce green hydrogen through electrolysis,a stable output with maximum possible capacity factor(CF)is generated to maintain the electricity grid ***,the trimmed energy is used in a secondary conversion path that minimizes the weighted average cost of the energy generated from the entire *** surplus power-to-gas conversion allows the use of green hydrogen to produce electricity,methanol,or ammonia subject to the resource availability,site characteristics,and financial *** on robust site selection criteria,the best performance is obtained at two sites:Ras Ghareb and Minya,achieving the lowest energy cost with some variance in their *** the Ras Ghareb site,the optimally sized RE plant provided the grid with a quasi-steady capacity of 423 MW with a CF of 80.04%and was capable of injecting 2965.8648 GWh throughout the year with the lowest cost of 2.4355¢/kWh.A surplus of 3.9%of the total energy produced from the plant was directed to produce 1922-ton H_(2)/year,achieving the lowest cost of hydrogen production of$1.9745/kg H_(2).For the other selected site,Minya,the clipped energy is used to produce 3330.47-ton H_(2)/year with an optimized lowest cost of$3.5268/kg H_(2).The difference in hydrogen costs was attributed to the number of full operating hours of the electrolyser in both *** cost is mainly affected by the electricity price and the electrolyser *** both tending to decrease,future forecasts show hydrogen cost reductions.

关键词： hybrid renewable-energy system(HRES) green hydrogen electrolysis power-to-gas methanol ammonia

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A review on the multi-scaled structures and mechanical/thermal properties of tool steels fabricated by laser powder bed fusion additive manufacturing

引用

International Journal of Minerals,Metallurgy and Materials 2024年第5期31卷 1048-1071页

作者： Huajing Zong Nan Kang Zehao Qin mohamed el Mansori Arts et Metiers Institute of Technology MSMPHESAM UniversitéChâlons-en-Champagne F-51006France Texas A&M Engineering Experiment Station Institute for Manufacturing SystemsCollege Station TX77843USA

The laser powder bed fusion(LPBF) process can integrally form geometrically complex and high-performance metallic parts that have attracted much interest,especially in the molds *** appearance of the LPBF makes it possible to design and produce complex conformal cooling channel systems in ***,LPBF-processed tool steels have attracted more and more *** complex thermal history in the LPBF process makes the microstructural characteristics and properties different from those of conventional manufactured tool *** paper provides an overview of LPBF-processed tool steels by describing the physical phenomena,the microstructural characteristics,and the mechanical/thermal properties,including tensile properties,wear resistance,and thermal *** microstructural characteristics are presented through a multiscale perspective,ranging from densification,meso-structure,microstructure,substructure in grains,to ***,a summary of tool steels and their challenges and outlooks are introduced.

关键词： additive manufacturing laser powder bed fusion tool steel multi-scaled structure mechanical properties thermal properties

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Research and development of Cordyceps in Taiwan

引用

Food Science and Human Wellness 2016年第4期5卷 177-185页

作者： Ching-Peng Chiu Tsong-Long Hwang You Chan mohamed el-shazly Tung-Ying Wu I-Wen Lo Yu-Ming Hsu Kuei-Hung Lai Ming-Feng Hou Shyng-Shiou Yuan Fang-Rong Chang Yang-Chang Wu Graduate Institute of Natural Products College of PharmacyKaohsiung Medical UniversityKaohsiung 80708TaiwanChina Graduate Institute of Natural Products College of MedicineChang Gung UniversityTaoyuan 33302TaiwanChina Research Center for Industry of Human Ecology and Graduate Institute of Health Industry Technology Chang Gung University of Science and TechnologyTaoyuan 33302TaiwanChina Department of Anesthesiology Chang Gung Memorial HospitalTaoyuan 33302TaiwanChina Department of Microbiology and Immunology and Institute of Microbiology and ImmunologySchool of MedicineChung Shan Medical UniversityTaichung 40201TaiwanChina Department of Pharmacognosy and Natural Products Chemistry Faculty of PharmacyAin-Shams UniversityCairoEgypt Chinese Medicine Research and Development Center China Medical University HospitalTaichung 40402TaiwanChina Cancer Center Kaohsiung Medical University HospitalKaohsiung 80708TaiwanChina Lipid Science and Aging Research Center Kaohsiung Medical UniversityKaohsiung 80708TaiwanChina Department of Marine Biotechnology and Resources National Sun Yat-sen UniversityKaohsiung 80424TaiwanChina Research Center for Environmental Medicine Kaohsiung Medical UniversityKaohsiung 80708TaiwanChina Center for Infectious Disease and Cancer Research Kaohsiung Medical UniversityKaohsiung 80708TaiwanChina School of Pharmacy College of PharmacyChina Medical UniversityTaichung 40402TaiwanChina Center of Molecular Medicine China Medical University HospitalTaichung 40402TaiwanChina

Cordyceps is treasured entomopathogenic fungi that have been used as antitumor,immunomodulating,antioxidant,and pro-sexual ***,also called DongChongXiaCao in Chinese,Yartsa Gunbu(Tibetan),means winter worm-summer *** Cordyceps sinensis with parasitic hosts is difficult to be collected and the recent findings on its potential pharmacological functions,resulted in skyrocketing ***,finding a mass-production method or an alternative for *** products is a top-priority *** this review,we describe current status of Cordyceps research and its recent developments in *** content and pharmacological activities of four major industrial species of Cordyceps(***,Cordyceps militaris,Cordyceps cicadae and Cordyceps sobolifera)used in Taiwan,were ***,we highlighted the effect of using different methods of fermentation and production on the morphology and chemical content of Cordyceps ***,we summarized the bottle-necks and challenges facing Cordyceps research as well as we proposed future road map for Cordyceps industry in Taiwan.

关键词： Entomopathogenic fungi Biofunction Cordyceps sp. C.sinensis C.militaris C.cicadae C.sobolifera

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Machine Learning and Data Fusion Approach for elastic Rock Properties Estimation and Fracturability Evaluation

引用

Energy and AI 2024年第2期16卷 1-13页

作者： Yiwen Gong Ilham el-Monier mohamed Mehana The Ohio State University SimTech LLC Los Alamos National Laboratory

Accurate rock elastic property determination is vital for effective hydraulic fracturing,particularly Young’s modulus due to its link to rock *** study integrates interdisciplinary data for better predictions of elastic modulus,combining data mining,experiments,and calibrated *** used the microstructural insights extracted from rock images for geomechanical facies ***,the petrophysical data and well logs were correlated with shear wave velocity(Vs)and Young’s *** developed a machine-learning workflow to predict Young’s modulus and assess rock fracturability,considering mineral composition,geomechanics,and *** findings indicate that artificial neural networks effectively predict Young’s modulus,while K-Means clustering and hierarchical support vector machines excel in identifying rock and geomechanical *** Microscale thin section analysis in conjunction with fracture modeling enhances our understanding of fracture geometries and facilitates fracturability ***,fracturability is controlled by specific geomechanical facies during initiation and propagation and influenced by continuity of geomechanical facies in small depth *** conclusion,this study demonstrates data mining and machine learning potential for predicting rock properties and assessing fracturability,aiding hydraulic fracturing design optimization through diverse data and advanced methods.

关键词： Young’s modulus prediction fracability evaluation landing point selection rock mechanics machine learning

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Genetic Variability and Phenotypic Correlations Study among Grain Quality Traits and Mineral elements Concentrations in Colored and Non-Colored Rice (Oryza sativa L.)

引用

Phyton-International Journal of Experimental Botany 2024年第7期93卷 1733-1748页

作者： Adel A.Rezk mohamed M.el-Malky Heba I.mohamed Hossam S.el-Beltagi Agricultural Biotechnology Department College of Agricultural and Food ScienceKing Faisal UniversityAl-Ahsa31982Saudi Arabia Plant Pathology Research Institute Agriculture Research CenterGiza12619Egypt Rice Research and Training Center Field Crop Research InstituteAgriculture Research Center33717Egypt Biological and Geological Sciences Department Faculty of EducationAin Shams UniversityCairo11511Egypt Biochemistry Department Faculty of AgricultureCairo UniversityGiza12613Egypt

Twenty-four rice genotypes were examined to assess genetic variability,heritability,and correlations for seven-grain quality traits,eight nutritional elements,and *** revealed signiﬁcant differences for the quality traits *** every trait under study,the phenotypic coefﬁcient of variation was higher than the correspon-dence genotypic coefﬁcient of *** in a broad sense varied from 29.75%for grain length to 98.31%for the elongation *** percentage recovery had a highly signiﬁcant positive correlation with milling and head rice ***,milling percentage had a highly positive correlation with head rice *** amylose percentage,all the genotypes belonged to low amylose except the Hassawi-1 variety,which had intermediate amylose *** nutrition contents of magnesium(Mg),sodium(Na),potas-sium(K),calcium(Ca),copper(Cu),manganese(Mn),zinc(Zn),iron(Fe),or protein percentage gave different variations for 24 rice genotypes under all the nutritional *** the 24 genotypes,ten rice genotypes–HighNutrient-1,HighNutrient-2,HighNutrient-9,HighNutrient-8,HighNutrient-3,Hassawi-2,HighNutrient-7,HighNutrient-6,Hassawi-1,and HighNutrient-4–had the highest heist value for all nutritional and protein con-tents,and could be used as a donor to improving new *** was a positive and signiﬁcant correlation between magnesium Mg,K,Zn and ***,K had a positive correlation with zinc Zn,Fe,and protein *** analysis was divided into two groups:theﬁrst group included all genotypes rich in nutri-ents,while the remaining genotypes with low nutritional content were included in the second group.

关键词： Amylose cluster analysis genotypes grain quality mineral nutrition rice

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：