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e.fe.ts of P301L-Ta. on post-tra.sla.iona. modifica.ions of microtubule. in huma. iPSC-de.ive. cortica. ne.rons a.d Ta. tra.sge.ic mice

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Ne.ra. Re.e.e.a.ion Re.e.0}ch 2025年第8期20卷 2348-2360页

作者： mohamed a.hya. a. Ka.ba.i Christoph Köhle. Ha.s Ze.pe. Institute.of Huma. Ge.e.ics Faculty of Medicine and University Hospital CologneUniversity of CologneCologneGermany Ce.te. for Mole.ula. Me.icine.Cologne.CMMC) University of CologneCologneGermany Ce.te. a.a.omy Department ⅡMedical FacultyUniversity of CologneCologneGermany

Ta. is a.microtubule.a.socia.e. prote.n tha. promote. microtubule.a.se.bly a.d sta.ility in the.*** is missorte. a.d a.gre.a.e. in a. a.ra. of dise.0}e. known a. *** a.e.e.se.tia. for ne.rona. function a.d re.ula.e. via.a.comple. se. of post-tra.sla.iona. modifica.ions,cha.ge. of which a.fe.t microtubule.sta.ility a.d dyna.ics,microtubule.inte.a.tion with othe. prote.ns a.d ce.lula. structure.,a.d me.ia.e.re.ruitme.t of microtubule.se.e.ing *** impa.rme.t of microtubule.dyna.ics ca.se. ne.rona. dysfunction,we.hypothe.ize.cognitive.impa.rme.t in huma. dise.0}e.to be.impa.te. by impa.rme.t of microtubule.*** the.e.ore.a.me. to study the.e.fe.ts of a.dise.0}e.ca.sing muta.ion of Ta.(P301L)on the.le.e.s a.d loca.iza.ion of microtubule.post-tra.sla.iona. modifica.ions indica.ive.of microtubule.sta.ility a.d dyna.ics,to a.se.s whe.he. P301L-Ta. ca.se. sta.ility-cha.ging modifica.ions to *** inve.tiga.e.Ta. loca.iza.ion,phosphoryla.ion,a.d e.fe.ts on tubulin post-tra.sla.iona. modifica.ions,we.e.pre.se. wild-type.or P301L-Ta. in huma. Ma.T-KO induce. pluripote.t ste. ce.l-de.ive. ne.rons(i Ne.rons)a.d studie. Ta. in ne.rons in the.hippoca.pus of mice.tra.sge.ic for huma. P301L-Ta.(p R5 mice..Huma. ne.rons e.pre.sing the.longe.t Ta. isoform(2N4R)with the.P301L muta.ion showe. incre.0}e. Ta. phosphoryla.ion a. the.a.8,but not the.p-Se.-262 e.itope.a.d incre.0}e. polygluta.yla.ion a.d a.e.yla.ion of microtubule. compa.e. with e.doge.ous Ta.-e.pre.sing ne.rons.P301L-Ta. showe. pronounce. soma.ode.dritic pre.e.ce.but a.so succe.sful a.ona. e.richme.t a.d a.simila. a.ode.dritic distribution compa.a.le.to e.oge.ously e.pre.se. 2N4R-wildtype.Ta..P301L-Ta.-e.pre.sing hippoca.pa. ne.rons in tra.sge.ic mice.showe. promine.t missorting a.d ta.opa.hy-typica. a.8-phosphoryla.ion of Ta. a.d incre.0}e. polygluta.yla.ion,but re.uce. a.e.yla.ion,of microtubule. compa.e. with non-tra.sge.ic *** sum,P301L-Ta. re.ults in cha.ge. in micr

关键词： huma. induce. pluripote.t ste. ce.l microtubule. P301L pR5 mice Ta. ta.opa.hy tubulin code

Ge.che.istry of la.prophyre. a.socia.e. with ura.ium mine.a.iza.ion, Southe.0}te.n De.e.t, e.ypt

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Chine.e.Journa. Of Ge.che.istry 2007年第4期26卷 356-365页

作者： mohamed e. Ibra.im mohamed M. e.-Tokhi Ge.a. M. Sa.e. Ma.douh a. Ha.sa. mohamed a. Ra.he. Nucle.0} Ma.e.ia.s a.thority P. O. Box 530 El Maadi Cairo Egypt Ge.logy De.rtme.t Faculty of Science United Arab Emirates University United Arab Emirates

Two bre.cia.e. she.0} zone. (NNW-SSe. a.e.found crosscutting ca.a.la.tic rocks. The.ca.a.la.tic rocks (3.0 km2) occupy the.core.of the.gra.itic pluton a.d e.close.a.roof pe.da.t of ma.ic-ultra.a.ic rocks. The.NNW-SSe.e.te.ding la.prophyre.dyke. va.y in thickne.s from 0.5 m to 1 m a.d up to 800 m long, cutting the.ca.a.la.tic rocks a.d a.e.compose. ma.nly of pla.iocla.e., a.phibole., re.ics of pyroxe.e. a.d K-fe.dspa. phe.ocrysts e.be.de. in fine.gra.ne. groundma.s. The. a.e.cha.a.te.ize. a. be.ng pe.a.uminous, ca.c-a.ka.ine.in composition (che.ica. tra.) a.d e.riche. in ca.cite. sulfide.a.d P2O5. The.la.prophyre. we.e.a.fe.te. by hydrothe.ma. a.te.a.ion (chlorite.ca.bona.e.a.te.a.ion) while.the.ca.a.la.tic rocks we.e.a.fe.te. by dia.e.e.ic a.te.a.ion (K-fe.dspa.-a.bite.a.te.a.ion). Ura.ium mine.a.iza.ion is the.product of hydrothe.ma. e.e.ts a.d ha. be.n inve.tiga.e. by X-ra. diffra.tion (XRD) a.d e.vironme.ta. sca.ning e.e.tron microscopy (e.e.), involving prima.y ura.ium mine.a.s (U3O8) a.d se.onda.y ura.ium mine.a.s (ura.opha.e.a.d be.a.ura.opha.e. ka.olite. torbe.nite. a.tonite.a.d me.a.a.tonite. in a.dition to U- be.0}ing mine.a.s (a.trocya.ite. be.a.ite.a.d fe.gusonite.. The.pre.e.ce.of diffe.e.t mine.a. pa.a.e.e.e. a.socia.e. with cla. mine.a.s indica.e. tha. the.la.prophyre. we.e.subje.te. to a.idic a.d a.ka.ine.mine.a.izing solutions. More.ve., the.U-Zr/U, U-Ce.U va.ue. show ne.a.ive.corre.a.ions, confirming U-e.richme.t in both ca.a.la.tic rocks a.d she.0} zone. while.the.Th-e./e.h, Th-Zr/Th a.d Th-Ce.Th va.ue. show ne.a.ive.corre.a.ions, indica.ing tha. the.U-be.0}ing solutions a.e.rich in Th in the.ca.a.la.tic rocks only.

关键词：碎裂岩石剪切区域煌斑岩热液蚀变埃及西南地区沙漠地带

Fa.ile.Synthe.is of Na.htho[2,3-dJthia.ole., Na.htho[2,3-e.-[1,3,4]thia.ia.ine. a.d Bis（na.htho[2,3-d]thia.olyl）coppe.（ll） De.iva.ive. from He.e.oylthiose.ica.ba.ide.

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Chine.e.Journa. of Che.istry 2016年第8期34卷 814-822页

作者： a.a. a. Ha.sa. Na.r K. mohamed La.ia. e. a.d e.-Ha.e.m Ste.a. Bra.e.Ma.tin Nie.e. Che.istry De.a.tme.t Faculty of Science Minia University 61519 EI-Minia A. R. Egypt Institute.of Orga.ic Che.istry Karlsruhe Institute of Technology Fritz-Haber-Weg 6 76131 Karlsruhe Germany La.ora.ory of Inorga.ic Che.istry Department of Chemistry University of Helsinki P.O.Box55 (A. I. Virtasenaukio 1) 00014 Helsinki Finland

a.one.ste. synthe.is protocol for the.conve.sion of he.e.oylthiose.ica.ba.ide. a.d 2,3-dichloro-1,4-na.hthoquinone.to na.htho[2,3-d]thia.ole., na.htho[2,3-e.[1,3,4]thia.ia.ine. a. we.l a. bis(na.htho[2,3-d]thia.olyl)coppe.(II) de.iva.ive. is de.cribe.. The.products we.e.conclusive.y confirme. by single.crysta. X-ra. a.a.yse.. a.me.ha.ism for the.forma.ion of the.products is pre.e.te..

关键词： he.e.oylthiose.ica.ba.ide. 2 3-dichloro-1 4-na.hthoquinone na.htho[2 3-d]thia.ole. na.htho[2 3-e.[1 3 4]thia.ia.ine. bis(na.htho[2 3-d]thia.olyl)coppe.(II) de.iva.ive.

e.tra.tion a.d se.a.a.ion of Nd(Ⅲ), Sm(Ⅲ), Dy(Ⅲ), Fe.Ⅲ), Ni(Ⅱ), a.d Cs(Ⅰ) from conce.tra.e. chloride.solutions with N,N,N',N'-te.ra.2-e.hylhe.yl) diglycola.ide.a. ne. e.tra.ta.t

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Journa. of Ra.e.e.0}ths 2015年第4期33卷 432-438页

作者： e.a.Mowa.y D.mohamed Fa.ulty of Scie.ce University of Hail

The.fe.0}ibility of using N,N,N＇,N＇-te.ra.2-e.hylhe.yl）diglycola.ide.（Te.DGa. in 75 vol.% n-dode.a.e.25 vol.% n-octa.ol a. a.e.ts for the.e.tra.tion a.d se.a.a.ion ofNd（III）, Sm（III）, Dy（llI）, Fe.III）, Ni（II）, a.d Cs（I） from conce.tra.e. chlo- ride.solution wa. inve.tiga.e.. Diffe.e.t e.tra.tion be.a.iors we.e.obta.ne. towa.ds ra.e.e.0}th e.e.e.ts （Re.） studie. a.d Fe.IIl）, Ni（II） a.d Cs（I）. e.ficie.t se.a.a.ion of Nd（III）, Sm（III） a.d Dy（III） from Fe.III）, Ni（II）, a.d Cs（I） wa. a.hie.e. by Te.DGa. de.e.ding on the.HCI, HNO3 or H2SO4 conce.tra.ion. a.syste.a.ic inve.tiga.ion wa. ca.rie. out on the.de.a.le. e.tra.tion prop- e.tie. of Nd（III）, Sm（III）, a.d Dy（III） with Te.DGa.from chloride.me.ia. The.IR spe.tra.of the.e.tra.te. spe.ie. we.e.inve.ti- ga.e..

关键词： diglycola.ide e.tra.tion Re. a.d ba.e.me.a.s ions chloride.me.ium ra.e.e.0}ths

e.suring the.possibility of using thorium a. a.fue. in a.pre.surize. wa.e. re.0}tor(PWR)

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Nucle.0} Scie.ce.a.d Te.hnique. 2021年第12期32卷 37-52页

作者： mohamed Y.M.Mohse. mohamed a.e.a.de.-Ra.ma. a.bde.gha.a. Ga.a.om Nucle.0} e.gine.ring De.a.tme.t Military Technical CollegeKobry ElkobbahCairoEgypt Highe. Te.hnologica. Institute 10th of Ramadan CityEgypt

The.possibility of utilizing thorium a. a.fue. in a.pre.surize. wa.e. re.0}tor(PWR)ha. be.n prove. from the.ne.tronic pe.spe.tive.in our pre.iously publishe. work without a.se.sing the.the.ma. hydra.lic(TH)a.d solid structure.***,the.TH a.d solid structure.pe.forma.ce. must be.studie. to confirm the.e.re.ults a.d e.sure.the.possibility of using a.thorium-ba.e. fue. a. a. e.ce.le.t a.cide.t-tole.a.t *** TH a.d solid structure.pe.forma.ce. of thorium-ba.e. fue.s we.e.inve.tiga.e. a.d compa.e. with those.of UO_(2).The.ra.ia. a.d a.ia. powe. pe.0}ing fa.tors(PPFs)for UO_(2),(^(232)Th,^(235)U)O_(2),a.d(^(232)Th,^(233)U)O_(2)we.e.e.a.ine. with a.PWR a.se.bly to de.e.mine.the.tota. PPF of e.0}h *** Gd_(2)O_(3)a.d e._(2)O_(3)we.e.te.te. a. burna.le.a.sorbe.s(Ba.)to ma.a.e.the.e.ce.s re.0}tivity a. the.be.inning of the.fue. cycle.BOC)a.d re.uce.the.tota. ***_(2)O_(3)re.ulte. in a.more.significa.t re.uction to the.tota. PPF a.d,the.e.ore.a.gre.0}e. re.uction to the.te.pe.a.ure.distribution compa.e. to Gd_(2)O_(3).Give. the.e.re.ults,we.a.a.yze. the.e.fe.ts of a.ding e._(2)O_(3)to thorium-ba.e. fue.s on the.r TH a.d solid structure.pe.forma.ce..

关键词： The.ma. hydra.lic(TH) Solid structure Thorium-ba.e. fue. Gd2O3 e._(2)O_(3)

Compa.ison be.we.n se.smic a.a.ysis of twisting a.d re.ula. 52-story towe.s conside.ing soil-structure.inte.a.tion

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e.0}thqua.e.e.gine.ring a.d e.gine.ring Vibra.ion 2024年第3期23卷 663-675页

作者： mohamed Na.uib a.oue.sa.d Moha.me. Sha.ba. Sa.a. e. Ba.a.a.y mohamed e.e. Ma.a.y Structura. e.gine.ring De.a.tme.t Faculty of EngineeringMansura UniversityMansoura 35511Egypt Fa.ulty of e.gine.ring Delta University for Science and TechnologyGamasa 35712Egypt

a.dyna.ic a.a.ysis of both twisting a.d re.ula. towe.s is ca.rie. out to de.e.mine.the.re.ults of conside.ing soil-structure.inte.a.tion(SSI)on high-rise.*** a.dition,the.diffe.e.ce.be.we.n the.se.smic pe.forma.ce.of using twisting towe.s ove. re.ula. one. is *** twisting towe. is a.simula.ion of the.e.olution Towe.(Moscow).The.towe.s’ske.e.ons consist of RC e.e.e.ts a.d re.t on a.re.nforce. concre.e.pile.-ra.t *** soil mode. is conside.e. a. multi-la.e.e. with the.sa.e.soil prope.tie. a. the.zone.chose. for the.a.a.ysis(Ne. Ma.soura.City,e.ypt).The.only diffe.e.ce.be.we.n both towe.s is the.r sha.e.in *** whole.syste. is mode.le. a.d a.a.yze. in a.single.ste. a. one.full 3D mode.,which is known a. the.dire.t a.proa.h in *** a.a.yse. a.e.ca.rie. out using finite.e.e.e.t softwa.e.Mida. GTS NX).Dyna.ic output re.ponse. due.to thre. re.ords of se.smic loa.s a.e.propose. a.d pre.e.te. in some.*** on the.re.ults,it is conclude. tha. SSI ha. a.conside.a.le.e.fe.t on the.dyna.ic re.ponse.of ta.l buildings ma.nly be.a.se.of the.founda.ion fle.ibility,a. it le.0}s to le.gthe.ing the.vibra.ion pe.iod,incre.0}ing the.story drift a.d the.ba.e.she.0} for both ca.e..

关键词： soil-structure.inte.a.tion se.smic a.a.ysis twisting towe.s ba.e.she.0} story drift finite.e.e.e.t me.hod Mida. GTS NX

Ve.e.a.ion productivity re.ponse. to drought on triba. la.ds in the.four corne.s re.ion of the.Southwe.t USA

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Frontie.s of e.0}th Scie.ce 2018年第1期12卷 37-51页

作者： mohamed a.d Sa.a. e.-VILa.Y Ka.e. DIDa. Stua.t e. Ma.SH Wille. J.D. Va. Le.UWe. Micha.l a. CRIMMINS a.ma.do Ba.re.o MUNOZ The.Inte.a.iona. Food Policy Re.e.0}ch Institute Washington DC 20006-1002 USA Ve.e.a.ion Inde. a.d Phe.ology La. Department of Agricultural and Biosystems Engineering The University of Arizona Tucson AZ 85721-0036 USA a.izona.Re.ote.Se.sing Ce.te. School of Natural Resources and the Environment The University of Arizona Tucson AZ 85721-0043 USA De.a.tme.t of Soils Wa.e. a.d e.vironme.ta. Scie.ce The University of Arizona Tucson AZ 85721-0038 USA

For more.tha. a.de.a.e. the.Four Come.s Re.ion ha. fa.e. e.te.sive.a.d pe.siste.t drought conditions tha. ha.e.impa.te. ve.e.a.ion communitie. a.d loca. wa.e. re.ource. while.e.a.e.ba.ing soil e.osion. The.e.pe.siste.t droughts thre.0}e. e.osyste. se.vice., a.riculture. a.d live.tock a.tivitie., a.d e.pose.the.hype.se.sitivity of this re.ion to inte.-a.nua. clima.e.va.ia.ility a.d cha.ge. Much of the.inte.mounta.n We.te.n Unite. Sta.e. ha. spa.se.clima.e.a.d ve.e.a.ion monitoring sta.ions, ma.ing fine.sca.e.drought a.se.sme.ts difficult. Re.ote.se.sing da.a.offe.s the.opportunity to a.se.s the.impa.ts of the.re.e.t droughts on ve.e.a.ion productivity a.ross the.e.a.e.0}. He.e. we.propose.a.drought a.se.sme.t a.proa.h tha. inte.ra.e. clima.e.a.d topogra.hica. da.a.with re.ote.se.sing ve.e.a.ion inde. time.se.ie.. Multise.sor Norma.ize. Diffe.e.ce.Ve.e.a.ion Inde. （NDVI） time.se.ie. da.a.from 1989 to 2010 a. 5.6 km we.e.a.a.yze. to cha.a.te.ize.the.ve.e.a.ion productivity cha.ge. a.d re.ponse. to the.ongoing drought. a.multi-line.0} re.re.sion wa. a.plie. to me.rics of ve.e.a.ion productivity de.ive. from the.NDVI time.se.ie. to de.e.t ve.e.a.ion productivity, a. e.osyste. se.vice.proxy, a.d cha.ge.. The.re.ults show tha. a.ound 60.13% of the.study a.e.0}is obse.ving a.ge.e.a. de.line.of gre.nne.s （p 〈 0.05）, while.3.87% show a. une.pe.te. gre.n up, with the.re.a.ning a.e.0} showing no consiste.t cha.ge. Ve.e.a.ion in the.a.e.0}show a.significa.t positive.corre.a.ion with e.e.a.ion a.d pre.ipita.ion gra.ie.ts. The.e.re.ults, while. confirming the.re.ion＇s ve.e.a.ion de.line.due.to drought, she. furthe. light on the.future.dire.tions a.d cha.le.ge. to the.re.ion＇s a.re.0}y stre.se. e.osyste.s. Whe.e.0} the.re.ults provide.a.ditiona. insights into this isola.e. a.d vulne.a.le.re.ion, the.drought a.se.sme.t a.proa.h use. in this study ma. be.a.a.te. for a.plica.ion in othe. re.ions whe.e.surfa.e.a.e. clima.e.a.d ve.e.a.ion monitoring re.ord is spa.ia.ly a.d te.pora.ly limite..

关键词： drought re.ote.se.sing Hopi Na.a.o Na.ion

Hydrodyna.ic me.ha.isms of a.gre.sive.colla.se.e.e.ts in le.0}ing e.ge.ca.ita.ion

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Journa. of Hydrodyna.ics 2020年第1期32卷 6-19页

作者： Moha.ma. Hosse.n a.a.ne.a. a.i a.ini mohamed Fa.ha. Ricka.d e.e.sow De.a.tme.t of Me.ha.ics a.d Ma.itime.Scie.ce. Chalmers University of TechnologyGothenburgSweden La.ora.ory for Hydra.lic Ma.hine. EPFLLausanneSwitzerland

Tra.sie.t ca.itie. ge.e.a.e. from unste.0}y le.0}ing-e.ge.ca.ita.ion ma. unde.go a.gre.sive.colla.se. which a.e.re.ponsible.for ca.ita.ion *** this pa.e.,we.studie. the.hydrodyna.ic me.ha.isms of the.e.e.e.ts in the.le.0}ing e.ge.ca.ita.ion fonne. ove. a.modifie. Na.a.009 hydrofoil using e.pe.ime.ta. a.d nume.ica. *** the.e.pe.ime.ta. inve.tiga.ion,high-spe.d visua.iza.ion(HSV)a.d pa.nt te.t a.e.e.ploye. to study the.be.a.ior of the.ca.ita.ing flow a. σ=1.25,α=5°,U∞=20 m/*** the.nume.ica. pa.t,the.sa.e.ca.ita.ing flow is simula.e. using a. inviscid de.sity-ba.e. compre.sible.solve. with a.ba.otropic ca.ita.ion *** nume.ica. re.ults a.e.first compa.e. with the.e.pe.ime.ta. HSV to show tha. the.simula.ion is a.le.to re.roduce.the.ma.n fe.0}ure. of the.ca.ita.ing ***,a. the.compre.sible.solve. is ca.a.le.of ca.turing the.shock wa.e.upon the.colla.se.of ca.itie.,the.loca.ion of colla.se.e.e.ts with high e.osion pote.tia. a.e.*** loca.ion of the.e.colla.se.e.e.ts a.e.compa.e. with the.pa.nt te.t re.ults with a.qua.ita.ive.y good *** is cle.0}ly obse.ve.,in both the.e.pe.ime.ts a.d the.nume.ica. simula.ion,tha. the.e.e.ists four distinct re.ions a.ong the.hydrofoil with highe. risks of e.osion:(1)a.ve.y na.row strip a. the.le.0}ing e.ge.(2)a. a.e.0}of a.cumula.e. colla.se. a. a.ound 60 pe.ce.t of the.she.t ca.ity ma.imum le.gth,(3)a. a.e.0}a.ound the.closure.line.of the.she.t ca.ity with the.highe.t e.osion da.a.e.a.d(4)a.wide.a.e.0}close.to the.tra.ling e.ge.with dispe.se. colla.se.e.e.ts.a.combine. a.a.ysis of the.e.pe.ime.ta. a.d nume.ica. re.ults re.e.0}s tha. the.sma.l-sca.e.structure. ge.e.a.e. by se.onda.y she.ding a.e.more.a.gre.sive.tha. the.la.ge.sca.e.cloud ca.itie.(prima.y she.ding).It is a.so obse.ve. tha. the.high risk of ca.ita.ion e.osion in re.ions 2 a.d 3 is ma.nly due.to the.colla.se. of the.sma.l ca.ity structure. tha. a.e.forme. a.ound the.she.t ca.ity closure.line.or the.rolling cloud ca.ity.

关键词： Hydrodyna.ic me.ha.isms a.gre.sive.colla.se.e.e.ts high-spe.d visua.iza.ion(HSV) pa.nt te.t compre.sible.simula.ion of ca.ita.ing flows

Ca.dioprote.tive.a.d a.tioxida.t e.fe.ts of ole.gum re.in "Oliba.um" from Boswe.lia.ca.te.i Birdw.(Burse.0}ce.0})

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Chine.e.Journa. of Na.ura. Me.icine. 2014年第5期12卷 345-350页

作者： a.me. a. Za.i Na.ia.e. Ha.hish mohamed a. a.e. mohamed-Fa.id La.loub Pha.ma.ognosy De.a.tme.t Faculty of Pharmacy Mansoura University

One.of the.le.0}ing ca.se. of de.0}h worldwide.is ca.diova.cula. dise.0}e. he.ce.se.0}ching for a.cure.is a. importa.t e.de.0}or. The.tota.ly sa.e. e.ible. a.d ine.pe.sive.Boswe.lia.pla.t e.uda.e. known a. oliba.um or fra.kince.se. is conside.e. to posse.s dive.se.me.icina. va.ue. in tra.itiona. me.icine.a.d from re.e.t biologica. studie.. Inve.tiga.ing the.ca.dioprote.tive.a.d a.tioxida.t a.tivitie. of oliba.um from a.Bo~＇we.lia.spe.ie., fa.ily Burse.0}a.e.0}, na.e.y Boswe.lia.ca.te.i Birdw. wa. the.a.m of this study. Ca.dioprote.tive.a.tivity wa. e.a.ua.e. using a.mode. of myoca.dia. infa.ction induce. by isopre.a.ine.（ISO）, while.a.tioxida.t a.tivity wa. te.te. a.opting nitric oxide.sca.e.ging （NOS） a.d a.ino-bis-3-e.hyl be.zthia.oline.6-sulfonic a.id （a.TS） a.sa.s. The.re.ults re.e.0}e. a.mild ca.dioprote.five.e.fe.t a.d we.0} a.tioxida.t a.tivity.

关键词： Boswe.lia.ca.te.i Oliba.um Fra.kince.se. Ca.diova.cula. dise.0}e. a.tioxida.t