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A Review on the Advancement of Renewable Natural Fiber Hybrid Composites: Prospects, Challenges, and Industrial Applications

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Journal of Renewable Materials 2024年第7期12卷 1237-1290页

作者： Mohammed Mohammed Jawad K.Oleiwi Aeshah M.Mohammed Anwar Ja’afar mohamad Jawad Azlin F.Osman Tijjani Adam Bashir O.Betar Subash C.B.Gopinath Center of Excellence Geopolymer&Green Technology(CEGeoGTech) Universiti Malaysia PerlisArau02600Malaysia Faculty of Chemical Engineering Technology Universiti Malaysia Perlis(UniMAP)Arau02600Malaysia Department of Materials Engineering University of TechnologyBaghdad10070Iraq Department of Chemical Materials University of Bagdad College of Education for Pure Science Ibn-AlhaithamBaghdad10001Iraq Department of Computer Techniques Engineering Al-Rafidain University CollegeBaghdad10001Iraq Faculty of Electronics Engineering Technology Universiti Malaysia PerlisKampus Uniciti Alam Sg.ChuchuhPerlis02100Malaysia Research Center(NANOCAT) University of MalayaKuala Lumpur50603Malaysia Institute of Nano Electronic Engineering Universiti Malaysia PerlisPerlis01000Malaysia Center for Global Health Research Saveetha Medical College&HospitalSaveetha Institute of Medical and Technical Sciences(SIMATS)Tamil Nadu602105India

Naturalﬁbre(NFR)reinforced functional polymer composites are quickly becoming an indispensable sustainable material in the transportation industry because of their lightweight,lower cost in manufacture,and adaptability to a wide variety of ***,the major difﬁculties of using theseﬁbres are their existing poor dimensional stability and the extreme *** assessing the mechanical properties(MP)of composites,the interfacial bonding(IB)happening between the NFR and the polymer matrix(PM)plays an incredibly signiﬁcant *** compared to NFR/syntheticﬁbre hybrid composites,hybrid composites(HC)made up of two separate NFR are less prevalent;yet,these hybrid composites also have the potential to be valuable materials in terms of environmental issues.A new dimension to theﬂexibility of composites reinforced with NFR is added by the cost-effective manufacture of hybrid composites utilising *** purpose of this study is to offer an over-view of the keyﬁndings that were presented on hybrid *** emphasis was focused on the factors that inﬂuence the performance of the naturalﬁber composites,diverse approaches to enhancing MP,physical,electri-cal,and thermal characteristics of the *** study in polymer science gains interest for applications in con-struction and automotive industries.

关键词： Renewable naturalﬁber hybrid composites sustainability nanomaterial greener material

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Driving forces of continuing evolution of rotaviruses

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World Journal of Virology 2024年第2期13卷 58-70页

作者： mohamad Saifudin hakim Faris Muhammad Gazali Suci Ardini Widyaningsih Mohammad Khalid Parvez Postgraduate School of Molecular Medicine Erasmus MC-University Medical CenterRotterdam 3015GDNetherlands Viral Infection Working Group International Society of Antimicrobial ChemotherapyLondon EC4R 9ANUnited Kingdom Master Program in Biotechnology Postgraduate SchoolUniversitas Gadjah MadaYogyakarta55281Indonesia Master of Medical Sciences in Clinical Investigation Harvard Medical SchoolBostonMA 02115United States Department of Pharmacognosy College of PharmacyKing Saud UniversityRiyadh11451Saudi Arabia

Rotaviruses are non-enveloped double-stranded RNA virus that causes acute diarrheal diseases in children(<5 years).More than 90%of the global rotavirus infection in humans was caused by Rotavirus group *** infection h... 详细信息

Rotaviruses are non-enveloped double-stranded RNA virus that causes acute diarrheal diseases in children(han 90%of the global rotavirus infection in humans was caused by Rotavirus group *** infection has caused more than 200000 deaths annually and predominantly occurs in the low-income *** evolution is indicated by the strain dynamics or the emergence of the unprecedented *** major factors that drive the rotavirus evolution include the genetic shift that is caused by the reassortment mechanism,either in the intra-or the ***,other factors are also known to have an impact on rotavirus *** review discusses the structure and types,epidemiology,and evolution of *** article also reviews other supplemental factors of rotavirus evolution,such as genetic reassortment,mutation rate,glycan specificity,vaccine introduction,the host immune respo-nses,and antiviral drugs.

关键词： Rotavirus Epidemiology Evolution Reassortment Vaccine

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乾隆朝清厘僧道停颁牒照档案(下)

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历史档案 2024年第3期 4-18页

作者：哈恩忠中国第一历史档案馆

广西巡抚臣杨锡绂谨奏,为奏明事。乾隆八年四月十二日准兵部加封递到大学士鄂等字寄内开,乾隆八年三月初七日奉上谕:二氏之教由来已久,其遵守戒律闭户焚修者固于民无害,即寻常僧道,或因无力营生,藉此以免饥寒,亦难尽行沙汰。但游手之徒... 详细信息

广西巡抚臣杨锡绂谨奏,为奏明事。乾隆八年四月十二日准兵部加封递到大学士鄂等字寄内开,乾隆八年三月初七日奉上谕:二氏之教由来已久,其遵守戒律闭户焚修者固于民无害,即寻常僧道,或因无力营生,藉此以免饥寒,亦难尽行沙汰。但游手之徒借名出家,耗民财而妨民俗,自不可听其引而日盛不为清厘。

关键词：广西巡抚乾隆朝僧道八年民俗杨锡绂

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A dose-dependent bimodal switch by homologous Aux/IAA transcriptional repressors

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Molecular Plant 2024年第9期17卷 1407-1422页

作者： Hyung-Taeg Cho Minsu Lee Hee-Seung Choi Kwang-Ho Maeng Kyeonghoon Lee ha-Yeon Lee Anindya Ganguly Hoonyoung Park Chang-Hoi Ho Department of Biological Sciences Seoul National UniversitySeoulKorea School of Earth and Environmental Sciences Seoul National UniversitySeoulKorea Department of Climate and Energy Systems Engineering Ewha Womans UniversitySeoulKorea

Combinatorial interactions between different regulators diversify and enrich the chance of transcriptional regulation in eukaryotic ***,a dose-dependent functional switch of homologous transcriptional repressors has rarely been ***,we show that SHY2,an auxin/indole-3-acetic acid(Aux/IAA)repressor,exhibits a dose-dependent bimodal role in auxin-sensitive root-hair growth and gene transcrip-tion in Arabidopsis,whereas other Aux/lAA homologs consistently repress the auxin *** co-repressor(TOPLESS[TPL])-binding affinity of a bimodal Aux/IAA was lower than that of a consistently re-pressing Aux/*** switch of a single amino acid residue in the TPL-binding motif between the bimodal form and the consistently repressing form switched their TPL-binding affinity and transcriptional and bio-logical roles in auxin *** on these data,we propose a model whereby competition between homologous repressors with different co-repressor-binding affinities could generate a bimodal output at thetranscriptional anddevelopmental levels.

关键词： auxin Aux/IAA dose-dependent regulation root hair transcription TOPLESS(TPL)

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CYP3A5 unexpectedly regulates glucose metabolism through the AKT-TXNIP-GLUT1 axis in pancreatic cancer

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Genes & Diseases 2024年第4期11卷 381-399页

作者： Ming Shao Qingfei Pan haiyan Tan Jing Wu ha Won Lee Andrew D.Huber William C.Wright Ji-Hoon Cho Jiyang Yu Junmin Peng Taosheng Chen Department of Chemical Biology and Therapeutics St.Jude Children's Research HospitalMemphisTN 38105USA Department of Computational Biology St.Jude Children's Research HospitalMemphisTN 38105USA Center for Proteomics and Metabolomics St.Jude Children's Research HospitalMemphisTN 38105USA Department of Structural Biology St.Jude Children's Research HospitalMemphisTN 38105USA Department of Developmental Neurobiology St.Jude Children's Research HospitalMemphisTN 38105USA

CYP3A5 is a cytochrome P450(CYP)enzyme that metabolizes drugs and contributes to drug resistance in ***,it remains unclear whether CYP3A5 directly influences cancer *** this report,we demonstrate that CYP3A5 regulates glucose metabolism in pancreatic ductal ***-omics analysis showed that CYP3A5 knockdown re-sults in a decrease in various glucose-related metabolites through its effect on glucose trans-port.A mechanistic study revealed that CYP3A5 enriches the glucose transporter GLUT1 at the plasma membrane by restricting the translation of TXNIP,a negative regulator of ***,CYP3A5-generated reactive oxygen species were proved to be responsible for atten-uating the AKT-4EBP1-TXNIP signaling ***3A5 contributes to cell migration by maintaining high glucose uptake in pancreatic *** together,our results,for the first time,reveal a role of CYP3A5 in glucose metabolism in pancreatic ductal adenocarcinoma and identify a novel mechanism that is a potential therapeutic target.

关键词： Cell migration CYP3A5 Glucose metabolism GLUT1 Pancreatic cancer TXNIP

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乾隆朝清厘僧道停颁牒照档案(上)

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历史档案 2024年第2期 4-20页

作者：无哈恩忠中国第一历史档案馆不详

度牒是官方颁发给出家僧道之合法身份证明。一般认为度牒始于北魏时期,唐代设立度牒制度,持有度牒的僧道可免除租税徭役、云游各处。清初依然沿袭度牒制度,康熙初年停止。乾隆帝登基后,为管理和控制僧道数量,予以恢复。由于度牒的特殊作... 详细信息

度牒是官方颁发给出家僧道之合法身份证明。一般认为度牒始于北魏时期,唐代设立度牒制度,持有度牒的僧道可免除租税徭役、云游各处。清初依然沿袭度牒制度,康熙初年停止。乾隆帝登基后,为管理和控制僧道数量,予以恢复。由于度牒的特殊作用,致遁入空门的僧道人数众多,“若辈不耕而食,不织而衣,且甘食美衣,公然以为分所应得”,其中鱼龙混杂,不免有“无赖游手”,甚至混入获罪逃匿者。加之度牒买卖转让,管理人员乘机借端需索,亦有害吏治。鉴于种种原因,乾隆三十九年(1774)六月颁布上谕:“所有礼部奏请给发牒照之处,着永远停止。”实行千年的度牒制度终被废除。档案中所称牒照亦指度牒。本组档案史料选编自中国第一历史档案馆藏内阁题本、宫中朱批奏折、军机处录副奏折及上谕档等,涉及乾隆中期以前清廷清厘僧道停颁度牒的系列内容,可供研究参考。

关键词：度牒录副奏折僧道身份证明乾隆朝北魏时期管理人员档案

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Prevalence and risk factors associated with metabolic dysfunctionassociated steatohepatitis in patients with Helicobacter pylori infection: A population-based study

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World Journal of Hepatology 2024年第10期16卷 1169-1176页

作者： Rashid Abdel-Razeq Lynn Bitar Elio R Bitar Chidera Onwuzo mohamad-Noor Abu-hammour Barish Eren Islam Mohamed Adejoke Johnson Antoine Boustany Somtochukwu Onwuzo Imad Asaad Department of Internal Medicine Cleveland Clinic FoundationClevelandOH 44111United States Faculty of Medicine Saint Joseph University of BeirutBeirut 11042020Lebanon Faculty of Medicine American University of BeirutBeirut 11072020Lebanon Department of Medicine&Surgery General Hospital Lagos IslandLagos Island 101223LagosNigeria Department of Internal Medicine Jacobi Medical Center/North Central Bronx HospitalBronxNY 10461United States Division of Gastroenterology Department of Internal MedicineUniversity of Florida College of MedicineJacksonvilleFL 32209United States Department of Gastroenterology Allegheny General HospitalPittsburghPA 15212United States Department of Gastroenterology Firelands HealthSanduskyOH 44870United States

BACKGROUND Helicobacter pylori(***)is associated with the development of gastrointestinal disorders ranging from gastritis to gastric *** evidence of the association between metabolic dysfunction-associated steatohepatitis(MASH)and *** infection in the literature is ***,we aim to evaluate the risk of developing MASH in patients who have had a diagnosis of *** infection independently of any confounding *** To evaluate the risk of developing MASH in patients who have had a diagnosis of *** *** This study used a validated multicenter research database of over 360 hospitals across 26 healthcare systems across the United States from 1999 to *** regression analysis assessed the risk of developing MASH,adjusting for confounders including *** infection,obesity,type 2 diabetes,hypertension,dyslipidemia,and male gender.A two-sided P value<0.05 was considered as statistically significant,and all statistical analyses were performed using R version 4.0.2(R Foundation for Statistical Computing,Vienna,Austria,2008).RESULTS A total of 79476132 individuals were screened in the database and 69232620 were selected in the final analysis after accounting for inclusion and exclusion ***(14.30%),patients with hyperlipidemia(70.35%),hypertension(73.86%),diabetes mellitus type 2(56.46%),and obese patients(58.15%)were more common in patients with MASH compared to *** a multivariate regression analysis,the risk of MASH was increased in diabetics[odds ratio(OR):3.55;95%CI:3.48-3.62],obese(OR:5.93;95%CI:5.81-6.04),males(OR:1.49;95%CI:1.46-1.52),individuals with hyperlipidemia(OR:2.43;95%CI:2.38-2.49)and *** infection(OR:2.51;95%CI:2.31-2.73).CONCLUSION This is the largest population-based study in the United States illustrating an increased prevalence and odds of developing MASH in patients with *** infection after adjusting for risk factors.

关键词： Metabolic dysfunction-associated steatohepatitis Metabolic dysfunction-associated steatotic liver disease Helicobacter Pylori Cirrhosis Liver

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Application of artifcial intelligence in cataract management:current and future directions

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Eye and Vision 2024年第1期10卷 21-30页

作者： Laura Gutierrez Jane Sujuan Lim Li Lian Foo Wei Yan Ng Michelle Yip Gilbert Yong San Lim Melissa Hsing Yi Wong Allan Fong mohamad Rosman Jodhbir Singth Mehta.ha.tian Lin Darren Shu Jeng Ting Daniel Shu Wei Ting Singapore Eye Research Institute SingaporeSingapore Singapore National Eye Center 11 Third Hospital AvenueSingapore 168751Singapore Academic Ophthalmology School of MedicineUniversity of NottinghamNottinghamUK Zhongshan Ophthalmic Center Sun Yet Sen UniversityGuangzhouChina

The rise of artifcial intelligence(AI)has brought breakthroughs in many areas of *** ophthalmology,AI has delivered robust results in the screening and detection of diabetic retinopathy,age-related macular degeneration,glaucoma,and retinopathy of *** management is another feld that can beneft from greater AI *** is the leading cause of reversible visual impairment with a rising global clinical *** diagnosis,monitoring,and surgical management are necessary to address this *** addition,patients in large developing countries often sufer from limited access to tertiary care,a problem further exacerbated by the ongoing COVID-19 *** on the other hand,can help transform cataract management by improving automation,efcacy and overcoming geographical ***,AI can be applied as a telediagnostic platform to screen and diagnose patients with cataract using slit-lamp and fundus *** utilizes a deep-learning,convolutional neural network(CNN)to detect and classify referable cataracts ***,some of the latest intraocular lens formulas have used AI to enhance prediction accuracy,achieving superior postoperative refractive results compared to traditional ***,AI can be used to augment cataract surgical skill training by identifying diferent phases of cataract surgery on video and to optimize operating theater workfows by accurately predicting the duration of surgical ***,some AI CNN models are able to efectively predict the progression of posterior capsule opacifcation and eventual need for YAG laser *** advances in AI could transform cataract management and enable delivery of efcient ophthalmic *** key challenges include ethical management of data,ensuring data security and privacy,demonstrating clinically acceptable performance,improving the generalizability of AI models across heterogeneous populations,and improving the trust of e

关键词： Artifcial intelligence Telemedicine Cataract Cataract screening Cataract surgery IOL calculations Biometry Machine learning

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越南学生汉语动物成语习得偏误分析

越南学生汉语动物成语习得偏误分析

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作者： TRUONG LE ha NHU 重庆交通大学

学位级别：硕士

汉语成语一直被认为是中华文化的精华,是汉语学习过程中不可忽视的一部分。现在学习汉语的越南人越来越多。对越南学生来说,仅会简单说一点汉语是不够的,他们希望了解更多成语,更深层次地了解汉语成语背后的文化,提高汉语运用能力。但... 详细信息

汉语成语一直被认为是中华文化的精华,是汉语学习过程中不可忽视的一部分。现在学习汉语的越南人越来越多。对越南学生来说,仅会简单说一点汉语是不够的,他们希望了解更多成语,更深层次地了解汉语成语背后的文化,提高汉语运用能力。但由于动物成语的丰富性、结构的稳定性、意义的整体性和语法功能的多样性以及汉语文化背景、风俗习惯的多元性,再加上两国的地理环境及国家的民族思维方式存在差异,两国人民对同一种动物的联想在认知和理解上也存在很多差异。这导致越南学生很难掌握动物成语知识,在应用成语中常常出现偏误。因此,笔者作为越南学生,为了帮助越南学生更深入地学习和理解汉语动物成语,拟研究越南学生在汉语动物成语习得过程中遇到的偏误,归纳偏误类型,分析偏误原因并提出针对性的学习策略。本研究通过深入分析汉语与越南语动物成语的构词特点和文化内涵差异,揭示了语言结构和文化背景理解不足是导致越南学生在学习汉语动物成语时产生偏误的主要原因。通过设计并实施调查问卷,详细分析了越南学生在汉语动物成语学习中的具体偏误类型,包括语义偏误、语法偏误和语用偏误。调查结果显示,这些偏误不仅影响了学生运用语言的准确性,也限制了他们对汉语文化深层次的理解。针对发现的问题,本文提出了相应的对策,旨在帮助越南学生克服学习障碍,深化对汉语动物成语及其背后文化的理解。这些对策包括加强文化背景知识学习、采用成语分类和归纳法,以及通过多样化的学习活动和资源创造丰富的学习环境。研究强调通过多媒体资源、实践互动和中越文化交流活动等手段,激发学生的学习兴趣,提高其汉语成语的实际应用能力。本研究对于汉语作为第二语言的教学实践具有重要意义。通过实施本研究提出的学习对策,不仅可以有效减少越南学生在汉语成语学习中的偏误,还可以促进中越文化的交流与理解,为越南学生提供一条深入学习汉语、提升跨文化交际能力的有效途径。

关键词：越南学生动物成语偏误分析学习策略

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Neuroprotective effect of liraglutide and memantine in a rat model of Alzheimer’s disease

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Asian Pacific Journal of Tropical Biomedicine 2024年第5期14卷 207-214页

作者： Duaa M.Bakhshwin Foziya W.a.ha.abi mohamad Omar Barasheed Ahmed M.Bakhshwin Maha H.Jamal Mohammed A.Bazuhair Fatemah O.Kamel Rania M.Magadmi Zoheir A Damanhouri Samar M.Alsaggaf Department of Clinical Pharmacology Faculty of MedicineKing Abdulaziz UniversityJeddahSaudi Arabia Hera General Hospital MakkahSaudi Arabia Department of Pathology Faculty of MedicineKing Abdulaziz UniversityJeddahSaudi Arabia Department of Clinical Anatomy Faculty of MedicineKing Abdulaziz UniversityJeddahSaudi Arabia

Objective:To assess the effect of memantine combined with liraglutide on aluminum chloride(AlCl_(3))and D-galactose(D-GAL)-induced neurotoxicity in ***:Male Wistar rats were divided into 5 groups of 5 animals each:the positive control,the negative control,the memantine-treated group,the liraglutide-treated group,and the combination group treated with memantine and ***_(3)and D-GAL were used to induce *** tests,brain beta-amyloid protein,and oxidative stress biomarkers were ***:The Morris water maze test indicated an enhanced memory in the combination ***,the combination treatment of liraglutide and memantine resulted in a remarkable reduction in the beta-amyloid protein level in the brain *** inflammation and oxidative stress biomarkers were significantly reduced,and the levels of antioxidant parameters were ***:The combination of liraglutide and memantine exerts neuroprotective effects and enhances memory and cognitive functions in rats with Alzheimer’s disease.

关键词： Alzheimer’s disease Cognitive function Glucagonlike peptide-1 Liraglutide Memantine

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