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mapping global research trends: Nutrition associations with nonalcoholic fatty liver disease - a Scopus bibliometric analysis

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World Journal of Gastroenterology 2024年第24期30卷 3106-3119页

作者： muna Shakhshir Sa'ed H Zyoud Department of Nutrition An-Najah National University HospitalNablus 44839Palestine Department of Public Health College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Department of Clinical and Community Pharmacy College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Poison Control and Drug Information Center College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Clinical Research Center An-Najah National University HospitalNablus 44839Palestine

BACKGROUND Several bibliometric analyses have been carried out to identify research hotspots and trends in nonalcoholic fatty liver disease(NAFLD)***,there are still significant knowledge gaps that must be filled to advance our understanding of and ability to treat *** To evaluate,through bibliometric and visual analysis,the current status of related research,related research frontiers,and the developmental trends in the field of diet and *** We retrieved publications about diet and NAFLD published between 1987 and 2022 from ***,we used VOSviewer 1.6.20 to perform bibliometric analysis and *** We found a total of 1905 studies,including 1637(85.93%)original articles and 195(10.24%)reviews,focused on the examination of NAFLD and its correlation with diet that were published between 1987 and *** the remaining five types of documents,38 were letters,notes,editorials,meeting minutes,or brief surveys,representing 1.99%of the total *** countries with the most publications on this topic were China(n=539;28.29%),followed by the United States(n=379;19.90%),Japan(n=133;6.98%),and South Korea(n=127;6.6%).According to the citation analysis,the retrieved papers were cited an average of 32.3 times and had an h-index of 106,with 61014 total *** two main clusters on the map included those related to:(1)Inflammation and oxidative stress;and(2)Dietary interventions for *** This was the first study to use data taken from Scopus to visualize network mapping in a novel bibliometric analysis of studies focused on diet and *** 2017,the two domains that received the most attention were“dietary interventions for NAFL”’and“‘inflammation and oxidative stress implicated in NAFLD and its correlation with diet.”We believe that this study provides important information for academics,dietitians,and doctors,and that additional research on dietary interventions and NAFLD is warranted.

关键词： Dietary Nutrition Bibliometric Nonalcoholic fatty liver Scopus VOSviewer

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Perspectives for delivery of therapeutics by extravasation of biodegradable microspheres in the brain

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Neural Regeneration Research 2024年第5期19卷 969-970页

作者： Anne-Eva van der Wijk ed VanBavel Amsterdam UmC location University of Amsterdam Department of Biomedical Engineering and PhysicsAmsterdamThe Netherlands Amsterdam Neuroscience Neurovascular Disorders ProgramAmsterdamThe Netherlands Amsterdam Cardiovascular Sciences Microcirculation ProgramAmsterdamThe Netherlands

Development of therapeutics for brain diseases has remained challenging,in particular due to the difficulty of passing the blood-brain *** a result,the current arsenal of therapeutics targeting the brain is limited to small,lipid-soluble drugs and there is a lack of options for treating neuroblastomas,Alzheimer’s disease,and many other devastating *** the advances in strategies for crossing the blood-brain barrier such as the use of nanoparticles(Hersh et al.,2022;Duan et al.,2023),such delivery systems have not yet reached clinical ***,novel platforms for the transport of therapeutics across the blood-brain barrier remain highly *** specifically holds for large molecules such as monoclonal antibodies and recombinant proteins,as well as nucleotide-based therapeutics and cell *** efforts in this field are increasing exponentially,with thousands of publications in the last few years.

关键词： therapeutics holds spite

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Alt Isoenzymes Highly Expressed in Fatty Liver, Regulated by Wy-14643 and Free Fatty Acids Treatment, and Increases Glyceroneogenesis

Alt Isoenzymes Highly Expressed in Fatty Liver, Regulated by...

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作者： SA’ed ANEES SAmOUR WORAIKAT 重庆医科大学

学位级别：硕士

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A multilayer Perceptron Artificial Neural Network Study of Fatal Road Traffic Crashes

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Journal of Data Analysis and Information Processing 2024年第3期12卷 419-431页

作者： ed Pearson III Aschalew Kassu Louisa Tembo Oluwatodimu Adegoke Department of electrical Engineering & Computer Science Alabama A&M University Normal AL USA Department of mechanical Civil Engineering & Construction Management Alabama A&M University Normal AL USA Department of mathematics and Computer Science Alabama State University Montgomery AL USA

This paper examines the relationship between fatal road traffic accidents and potential predictors using multilayer perceptron artificial neural network (mLANN) models. The initial analysis employed twelve potential predictors, including traffic volume, prevailing weather conditions, roadway characteristics and features, drivers’ age and gender, and number of lanes. Based on the output of the model and the variables’ importance factors, seven significant variables are identified and used for further analysis to improve the performance of models. The model is optimized by systematically changing the parameters, including the number of hidden layers and the activation function of both the hidden and output layers. The performances of the mLANN models are evaluated using the percentage of the achieved accuracy, R-squared, and Sum of Square Error (SSE) functions.

关键词： Artificial Neural Network multilayer Perceptron Fatal Crash Traffic Safety

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mapping the global research landscape on nonalcoholic fatty liver disease and insulin resistance:A visualization and bibliometric study

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World Journal of Hepatology 2024年第6期16卷 951-965页

作者： Sa'ed H Zyoud Omar E Hegazi Samer O Alalalmeh muna Shakhshir Faris Abushamma Shadi Khilfeh Samah W Al-Jabi Department of Clinical and Community Pharmacy College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Clinical Research Center An-Najah National University HospitalNablus 44839Palestine College of Pharmacy and Health Sciences Ajman UniversityAjman 346United Arab Emirates Department of Nutrition An-Najah National University HospitalNablus 44839Palestine Department of medicine College of Medicine and Health SciencesAn-Najah National UniversityNablus 44839Palestine Department of Urology An-Najah National University HospitalNablus 44839Palestine Department of Gastroenterology Hepatology and EndoscopyAn-Najah National University HospitalNablus 44839Palestine

BACKGROUND Nonalcoholic fatty liver disease(NAFLD)is a liver condition that is prevalent worldwide and associated with significant health risks and economic *** it has been linked to insulin resistance(IR),this study aimed to perform a bibliometric analysis and visually represent the scientific literature on IR and *** To map the research landscape to underscore critical areas of focus,influential studies,and future directions of NAFLD and *** This study conducted a bibliometric analysis of the literature on IR and NAFLD indexed in the SciVerse Scopus database from 1999 to *** search strategy used terms from the literature and medical subject headings,focusing on terms related to IR and *** software was used to visualize research trends,collaborations,and key thematic *** analysis examined publication type,annual research output,contributing countries and institutions,funding agencies,journal impact factors,citation patterns,and highly cited *** This analysis identified 23124 documents on NAFLD,revealing a significant increase in the number of publications between 1999 and *** search retrieved 715 papers on IR and NAFLD,including 573(80.14%)articles and 88(12.31%)*** most productive countries were China(n=134;18.74%),the United States(n=122;17.06%),Italy(n=97;13.57%),and Japan(n=41;5.73%).The leading institutions included the Universitàdegli Studi di Torino,Italy(n=29;4.06%),and the Consiglio Nazionale delle Ricerche,Italy(n=19;2.66%).The top funding agencies were the National Institute of Diabetes and Digestive and Kidney Diseases in the United States(n=48;6.71%),and the National Natural Science Foundation of China(n=37;5.17%).The most active journals in this field were Hepatology(27 publications),the Journal of Hepatology(17 publications),and the Journal of Clinical Endocrinology and metabolism(13 publications).The main research hotspots were“therapeutic approaches for IR and NAFLD”and“inflamma

关键词： Nonalcoholic fatty liver disease Insulin resistance Bibliometric Visualization

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A NEW HYBRIDIZed mIXed WEAK GALERKIN mETHOD FOR SECOND-ORDER elLIPTIC PROBLEmS

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Journal of Computational mathematics 2022年第4期40卷 499-516页

作者： Abdelhamid Zaghdani sayed Sayari miled el Hajji University of Tunis Boulevard du 9 avril 1939 TunisDepartment of MathematicsEnsitTaha Hussein AvenueMontfleuryTunisTunisia Northern Border University Faculty of Arts and ScienceRafhaP.O.840Saudi Arabia Carthage University Isteub2 Rue de l’Artisanat Charguia 22035 TunisTunisia Department of mathematics Faculty of SciencesUniversity of JeddahSaudi Arabia ENIT-LAMSINBP.371002 Tunis-Belv´ed`ereTunis El Manar UniversityTunisia

In this paper,a new hybridized mixed formulation of weak Galerkin method is studied for a second order elliptic *** method is designed by approximate some operators with discontinuous piecewise polynomials in a shape regular finite element *** discrete inequalities are presented on discontinuous spaces and optimal order error estimations are *** numerical results are reported to show super convergence and confirm the theory of the mixed weak Galerkin method.

关键词： Weak Galerkin Weak gradient Hybridized mixed finite element method Second order elliptic problems

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Geothermobarometry of Askaoun Pluton in Ouzellarh-Sirwa Promontory (Central Anti-Atlas;morocco)

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Open Journal of Geology 2012年第3期2卷 136-147页

作者： Abdeslam Toummite moha Ikenne el Hassane Beraaouz Applied Geology and Environmental Geology Laboratory Faculty of Sciences Ibn Zohr University Agadir Morocco

Rocks of the late Neoproterozoic Askaoun pluton (558 ± 2 ma) located in the Ouzellarh-Sirwa promontory (Anti-Atlas) include magmatic microgranular enclaves (mmEs) ranging from rounded to ovoid in shape, dark and fine grained and generally 5 to 10 cm in size, some reaching a size of 50 cm. They are composed of microdiorite, quartz microdiorite and micromonzodiorite, whereas the felsic host rocks comprise mainly quartz-diorite and amphibole-biotite granodiorite based on mineralogical compositions. The mineral assemblage is similar to those described in their hosting granitoids but with different proportions. In this study composition of minerals is used to describe the nature of the magma and estimate the pressure, temperature and oxygen fugacity at which Askaoun pluton is emplaced. Based on chemistry of biotite Askaoun pluton formed from calc-alkaline magma. Compositions of plagioclase (An5 - An29);hornblende (mg ≠= 0.59 - 0.65) and biotite (mg ≠= 0.49 - 0.55) of mmEs are slightly distinct or similar to those of host rocks (An7-40;hbl mg ≠= 0.64 - 0.69;Bi mg ≠= 0.49 - 0.50) which suggest partial to complete equilibration during mafic-felsic magma interaction. The coexisting hornblende and plagioclase (hornblende-plagioclase thermometry), Al content in hornblende (aluminum-in-hornblende barometry) and the assemblage titanite-magnetite-quartz were used to constrain the P, T and fO2 during the crystallization of the parent magmas. The Askaoun pluton was emplaced at temperature ca. 504°C - 633°C and at pressure ca. 0.9 - 4.66 ± 0.6 Kbars (average depth = 6.5 km) from a highly oxidized magma (log fO2 = ?24.8 to ?19.2).

关键词： Askaoun Pluton mmEs Hornblende Thermobarometry Ouzellargh-Sirwa Promontory Anti-Atlas morocco

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Estimation of metformin Drug for the Diabetes Patients by Simple,Quick and Cheap Techniques within the Formation of Colored Charge Transfer Complexes

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光谱学与光谱分析 2018年第11期38卷 3622-3630页

作者： Omar B.Ibrahim.el-sayed A.manaaa m.m.AL-majthoub Ahm ed m.Fallatah Abdel majid A.Adam mha m.Alatibi Jehan Y.A l-Humaidi moamen S.Refat Department of Chemistry Faculty of ScienceTaif UniversityAl-HaweiahP.O.Box 888Zip Code 21974TaifSaudi Arabia Department of Chemistry Faculty of Applied Medical ScienceTaif Unive rsityKSA Nuclear materials Authority El-MaadiEgypt Department of Chemistry College of SciencePrincess Nourah bint Abdulrahman UniversityRiyadh 11671KSA Department of Chemistry Faculty of SciencePort Said UniversityPort SaidEgypt

metformin(met)is a drug developed for the treatment of patients with typeⅡ ***,met estimation in pharmaceutical formulations and human fluids has gained a growing *** extend requisite data that can be used to assessment of met quantitatively based on charge-transfer(CT)complexation,the present study describes the synthesis and characterization of CT complexes that formed between drug met and the organicπ-acceptors picric acid(PA),chloranilic acid(CLA),chloranil(CHL),7,7',8,8'-tetracyanoquinodimethane(TCNQ),and dichlorodicyanobenzoquinone(DDQ).The properties of the formed CT complexes were investigated by elemental,spectral(UV-visible,IR,and Raman spectroscopies),thermal(TG)and morphological(SEm)*** results indicated that the complexation of met with either PA or CLA acceptors occurs through proton transfer interaction,whereas its complexation with CHL,TCNQ,or DDQ acceptors occurs through n→π*interaction.

关键词： metformin Anti-diabetic drug Charge-t ransfer complex Acceptor Solution study

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Fritz Ackermann:a true and unequalled friend

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Geo-Spatial Information Science 2023年第2期26卷 151-152页

作者： ed mikhail Professor Emeritus&Former Head Geomatics Engineering Purdue UniversityWest LafayetteINUSA

I am certain that several other contributors to this memorial volume have expounded on the many attributes,both professional and personal,of Professor Fritz *** is unquestionable that he was a giant in our field,on whose shoulders current and future practitioners shall stand in order to keep the wheels of progress and advancement moving forward.

关键词： moving Fritz Ackermann

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Integrative herbal treatments of diabetes in Beni mellal region of morocco

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Journal of Integrative medicine 2019年第2期17卷 93-99页

作者： Hanae Naceiri mrabti Nidal Jaradat moha.ed Reda Kachmar Abdelaziz ed-Dra Abdelilah Ouahbi Yahia Cherrah moulay el Abbes Faouzi Faculty of medicine and Pharmacy Pharmacokinetic Team Laboratory of Pharmacology and Toxicology Université Mohammed V-Souissi Department of Pharmacy Faculty of Medicine and Health Sciences An-Najah National University Faculty of Sciences Health and Environment Laboratory Plant Protection Team Moulay Ismail University Faculty of Science Team of Microbiology and Health Laboratory of Chemistry-Biology Applied to the Environment Moulay Ismail University

Objectives: Diabetes is one of the most life-threatening chronic metabolic disorders and is considered a global health problem due to its prevalence and incidence. In morocco, several herbal preparations are utilized to treat this disease. For this reason, the current study aimed to identify and to collect data about the medicinal plants utilized in folk medicine for the treatment of diabetes in the Beni mellal region of ***: An ethnobotanical survey was carried out among 400 herbalists, competent villagers and traditional healers from the Beni mellal region through direct interviews using a semistructured ***: Forty-five medicinal plants belonging to 25 families were identified for their use in diabetes treatment. Interview results showed that the most frequently used plants were Olea europaea, Salvia officinalis, Allium sativum and Trigonella foenum-graecum, with a relative frequency of citation values of24.3%, 23.0%, 22.5% and 20.5%, respectively. moreover, in this study, the Fabaceae family was the most commonly reported plant family, and the leaves and roots were the most commonly used parts, for the treatment of ***: The Beni mellal region of morocco has an important floristic biodiversity of plants used to treat diabetes in traditional medicinal practice. This result provides a good database for pharmacological screenings in the search for plant-based antidiabetic medications.

关键词： Integrative medicine medicinal plants Diabetes Beni mellal morocco Questionnaire

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