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Role of urine studies in asymptomatic febrile neutropenic patients presenting to the emergency department

World Journal of Emergency Medicine 2021年第2期12卷 99-104页

作者： Hady Zgheib Aline el Zakhem Cynthia Wakil mohamad Ali Cheaito Rola Cheaito Antoine Finianos Ralphe Bou Chebl Rima Kaddoura Nader Al Souky Imad el Majzoub Department of Emergency Medicine American University of Beirut Medical CenterBeirut 11-0236Lebanon Department of Internal Medicine American University of Beirut Medical CenterBeirut 11-0236Lebanon

BACKGROUND: The role of urine studies in the detection of urinary tract infection(UTI) in febrile neutropenic patients with urinary symptoms(having a urinary catheter or having a positive urine analysis) is inarguable. However, the evidence is scarce regarding the indication for urine studies in asymptomatic(i.e., without urinary symptoms) patients with febrile neutropenia(FN) presenting to the emergency department(ed). The aim of this study is to evaluate the need for obtaining urine studies in asymptomatic febrile neutropenic ***: This was a retrospective cohort study conducted on adult cancer patients who presented to the ed with FN and had no urinary symptoms. We included all ed presentations of eligible patients between January 2013 and September 2018. Student's t-test and Wilcoxon rank-sum test were used for continuous data, while Chi-square and Fisher's exact tests were used for categorical data. Participants were divided into two groups based on their urine culture(UC) results: negative and positive UCs. Two cut-offs were used for positive UC results: ≥10~5 cfu/m L and ≥10~4 cfu/m ***: We included 284 patients in our study. The age of our patient population was 48.5±18.5 years. More than two-thirds(68.7%) of patients had severe neutropenia, while only 3.9% and 9.9% of the patients had positive UCs at ≥10~5 cfu/m L and ≥10~4 cfu/m L, respectively. UCs were expectedly positive in most patients with urinalysis(UA) abnormalities. However, 27.3% and 32.1% of patients with positive UCs at ≥10~5 cfu/m L and ≥10~4 cfu/m L respectively had a normal UA. CONCLUSIONS: In our study, the incidence of UTI in adult febrile neutropenic cancer patients who present to the ed without urinary symptoms is low. Consequently, routine urine testing may not be warranted in this population, as it adds unnecessary financial burdens on the patients and delays timely management.

关键词： Adult Cancer Emergency department Febrile neutropenia Urine testing

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涕灭威对努比亚山羊的毒性

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动物毒物学 1995年第1期10卷 46-48页

作者： moha.,OS 孙素玲

给努比亚山羊一次灌服１５０、３７．５和５ｍｇ／ｋｇ涕灭威后５－１８０分钟出现明显的中毒症状和死亡。每天灌服０．５－０．１ｍｇ／ｋｇ，５－４０天山羊死亡。临床上出现神经症状则预示着羊快要死亡。文中描述了病理学、血液学和... 详细信息

给努比亚山羊一次灌服１５０、３７．５和５ｍｇ／ｋｇ涕灭威后５－１８０分钟出现明显的中毒症状和死亡。每天灌服０．５－０．１ｍｇ／ｋｇ，５－４０天山羊死亡。临床上出现神经症状则预示着羊快要死亡。文中描述了病理学、血液学和生物化学的变化。

关键词：涕灭威山羊中毒毒性羊病

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Global standard names for the Lowermost Cambrian Series and Stage

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Episodes 2007年第4期30卷 287-289页

作者： ed Landing Shanchi Peng Loren E. Babcock Gerd Geyer Malgorzata Moczydlowska- Vidal New york State Museum Madison Avenue Albany New York 12230 USA. State Key Laboratory of Stratigraphy and Palaeobiology Nanjing Institute of Geology and Palaeontology 39 East Beijing Road Nanjing 210008 China School of Earth Sciences The Ohio State University Columbus Ohio 43210 USA Institut für Palaiontologie Bayerische Julius-Maximillians-Universitat Pleicherwall 1 D97070 Würzburg Germany Department of Earth Sciences Uppsala University Norbyvaigen 22 Sweden.

The GSSP marking the base of the Cambrian System was ratified by the lUGS in 1992. Ratification of the GSSP point at the base of the Trichophycus pedum Ichnozone in the Fortune Head section, eastern Newfoundland, Canada, automatically defined the conterminant base of the lowermost series and stage of the Cambrian although names for those subdivisions were not proposed at the time of the decision. In 2007, the lUGS ratified the names Terreneuvian Series and Fortunian Stage for these previously unnamed chronostratigraphic subdivisions. The Terreneuvian Series replaces the provisional name ＂Series 1,＂ and the Fortunian Stage replaces the provisional name ＂Stage 1,＂ of the Cambrian System.

关键词：寒武纪全球标准地质学测量方法

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Recognition and Management of Athletic Pubalgia

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中国运动医学杂志 2011年第8期30卷 759-763页

作者： Paul R.Geisler ed.D,ATC Department of Exercise & Sport Sciences Ithaca CollegeNYUSA.

Introduction Whether termed"sports hernias","hockey groin",or"athletic pubalgia",insidious onset and vague groin and hip maladies seem to be on the rise in the last few years,creating much confusion as to the best way... 详细信息

关键词：《中国运动医学杂志》期刊摘要编辑部

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Accept＆Proceed

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计算机光盘软件与应用（COMPUTER ARTS数码艺术） 2008年第4期 44-50页

作者： ed RICKETTS

“我所进行的许多处理．都是为了弥补之前的不足；它们能打消客户的疑虑。”David Johnston为你讲述自从建立了Accept＆Proceed以来所学到的东西……

关键词：商标设计师艺术作品 Accept&Proceed

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EXERCISE，ANTIOXIDANTS，AND CARDIOPROTECTION

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中国运动医学杂志 2004年第1期23卷 57-63页

作者： ScottK.Powers Ph.D. ed.D. DepartmentofExerciseandSportSciences DepartmentofPhysiology UnwenityofFloridaGainesville FloridaU.S.A.

Cardiovascular disease continues to be the number one cause of death in the United States.

关键词：运动抗氧化剂心功能保护心血管疾病冠状动脉疾病

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Mosby's review questions for NCLEX-RN

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2001年

作者： ed. by Dolores F. Saxton

来源：畅想之星图书光盘版（南... 评论

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Self-portraits

Self-portraits

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作者： Ernst Rebel Norbert Wolf (ed.)

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Brucke

Brucke

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作者： Ulrike Lorenz Norbert Wolf ed.

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Allelic functional variation of FimH among Salmonella enterica subspecies

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Animal Diseases 2023年第4期3卷 265-274页

作者： Xiamei Kang Jiaqi Chen Xiao Zhou Abdelaziz ed-Dra Min yue Instituteof Preventive Veterinary Sciences&Department of Veterinary Medicine Zhejiang University College of Animal SciencesHangzhou 310058China Laboratory of Engineering and Applied Technologies Higher School of TechnologySultan Moulay Slimane UniversityPB:591Mghila University Campus23000Beni MellalMorocco Hainan Institute of Zhejiang University SanyaChina Zhejiang Provincial Key Laboratory of Preventive Veterinary Medicine Hangzhou 310058China

Salmonella enterica has a wide diversity,with numerous serovars belonging to six different subspecies with dynamic animal-host *** FimH protein is the adhesin mediating binding to various cells,and slight amino acid discrepancy significantly affects the adherence *** date,the general function of FimH variability across dif-ferent subspecies of Salmonella enterica has not been *** investigate the biological functions of FimH among the six Salmonella enterica subspecies,the present study performed several assays to determine biofilm for-mation,Caenorhabditis elegans killing,and intestinal porcine enterocyte cell IPEC-J2 adhesion by using various FimH allele *** general,allelic mutations in both the lectin and pilin domains of FimH could cause changes in bind-ing affnity,such as the N79S *** also observed that the N79S variation in Salmonella Dublin increased the adhesive ability of IPEC-J2 ***,a new amino acid substitution,T260M,within the pilin domain in one subspecies llb strain beneficial to binding to cells was highlighted in this study,even though the biofilm-forming and Caenorhabditis elegans-killing abilities exhibited no significant differences in *** with point muta-tions being a natural tendency due to positive selection in harsh environments,we speculate that allelic variation T26oM probably contributes to pathoadaptive evolution in Salmonella enterica subspecies llb.

关键词： Salmonella subspecies FimH Amino acid substitution Binding Allelic variation

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