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World Journal of Cardiology 2024年第8期16卷 469-483页

作者： moaz safwan Mariam safwan Bourgleh Mohamed Aldoush Khawaja Husnain Haider Department of Basic Sciences Sulaiman Al Rajhi UniversityAl Bukairiyah 51941Saudi Arabia

BACKGROUND Mesenchymal stem cells(MSCs),as living biodrugs,have entered advanced phases of clinical assessment for cardiac function restoration in patients with myocardial infarction and heart *** MSCs are available from diverse tissue sources,bone-marrow-derived MSCs(BM-MSCs)remain the most wellstudied cell type,besides umbilical-cord-derived MSCs(UC-MSCs).The latter offers advantages,including noninvasive availability without ethical *** To compare the safety and efficacy of BM-MSCs and UC-MSCs in terms of left ventricular ejection fraction(LVEF),6-min walking distance(6MWD),and major adverse cardiac events(MACEs).METHODS Five databases were systematically searched to identify randomized controlled trials(RCTs).Thirteen RCTs(693 patients)were included using predefined eligibility *** mean differences and odds ratio(OR)for the changes in the estimated treatment *** UC-MSCs significantly improved LVEF vs controls by 5.08%[95%confidence interval(CI):2.20%-7.95%]at 6 mo and 2.78%(95%CI:0.86%-4.70%)at 12 ***,no significant effect was observed for BM-MSCs vs *** significant changes were observed in the 6MWD with either of the two cell ***,no differences were observed for MACEs,except rehospitalization rates,which were lower only with BM-MSCs(odds ratio 0.48,95%CI:0.24-0.97)vs *** UC-MSCs significantly improved LVEF compared with *** advant-safwan M et ***-source and MSCs as living biodrugs ageous characteristics position them as a promising alternative to MSC-based therapy.

关键词： Cardiovascular disease Heart disease Mesenchymal stem cells Umbilical cord stem cells

Simulation of Fracture Process of Lightweight Aggregate Concrete Based on Digital Image Processing Technology

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Computers, Materials & Continua 2024年第6期79卷 4169-4195页

作者： safwan Al-sayed Xi Wang Yijiang Peng Key Laboratory of Urban Security and Disaster Engineering Ministry of EducationBeijing University of TechnologyBeijing100124China

The mechanical properties and failure mechanism of lightweight aggregate concrete(LWAC)is a hot topic in the engineering field,and the relationship between its microstructure and macroscopic mechanical properties is also a frontier research topic in the academic *** this study,the image processing technology is used to establish a micro-structure model of lightweight aggregate *** the information extraction and processing of the section image of actual light aggregate concrete specimens,the mesostructural model of light aggregate concrete with real aggregate characteristics is *** numerical simulation of uniaxial tensile test,uniaxial compression test and three-point bending test of lightweight aggregate concrete are carried out using a new finite element method-the base force element method ***,the image processing technology is used to produce beam specimens,uniaxial compression specimens and uniaxial tensile specimens of light aggregate concrete,which can better simulate the aggregate shape and random distribution of real light aggregate ***,the three-point bending test is numerically ***,the uniaxial compression specimen generated by image processing technology is numerically ***,the uniaxial tensile specimen generated by image processing technology is numerically *** mechanical behavior and damage mode of the specimen during loading were *** results of numerical simulation are compared and analyzed with those of relevant *** feasibility and correctness of the micromodel established in this study for analyzing the micromechanics of lightweight aggregate concrete materials are *** processing technology has a broad application prospect in the field of concrete mesoscopic damage analysis.

关键词： Digital image processing lightweight aggregate concrete mesoscopic model numerical simulation fracture analysis bending beams

Decision Aid Model for Private-owned Electric Vehicles Participating in Frequency Regulation Ancillary Service Market

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Journal of Modern Power Systems and Clean Energy 2024年第2期12卷 621-629页

作者： Liwei Wang Yingyun Sun Haotian Wang Pengfei Zhao Muhammad safwan Jaffar School of Electrical and Electronic Engineering North China Electric Power UniversityBeijing 102206China

To reduce the difficulty and enhance the enthusiasm of private-owned electric vehicles(EVs) in participating in frequency regulation ancillary service market(FRASM), a decision aid model(DAM) is proposed. This paper presents three options for EV participating in FRASM, i. e., the base mode(BM), unidirectional charging mode(UCM), and bidirectional charging/discharging mode(BCDM), based on a reasonable simplification of users' participating willingness. In BM, individual EVs will not be involved in FRASM, and DAM will assist users to set the optimal charging schemes based on travel plans under the time-of-use(TOU) price. UCM and BCDM are two modes in which EVs can take part in FRASM. DAM can assist EV users to create their quotation plan, which includes hourly upper and lower reserve capabilities and regulation market mileage prices. In UCM and BCDM, the difference is that only the charging rate can be adjusted in the UCM, and the EVs in BCDM can not only charge but also discharge if necessary. DAM can estimate the expected revenue of all three modes, and EV users can make the final decision based on their preferences. Simulation results indicate that all the three modes of DAM can reduce the cost, while BCDM can get the maximum expected revenue.

关键词： Electric vehicle(EV) frequency regulation decision aid model(DAM) utility maximization battery wear cost

Assessment of the environmental kuznets curve within EU-27:Steps toward environmental sustainability(1990-2019)

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Environmental Science and Ecotechnology 2024年第2期18卷 91-103页

作者： safwan Mohammed Abid Rashid Gill Kaushik Ghosal Main Al-Dalahmeh Karam Alsafadi Szilárd Szabó Judit Oláh Ali Alkerdi Akasairi Ocwa Endre Harsanyi Institute of Land Use Engineering and Precision Farming TechnologyFaculty of Agricultural and Food Sciences and Environmental ManagementUniversity of DebrecenBöszörményi 138H-4032DebrecenHungary Institutes for Agricultural Research and Educational Farm University of DebrecenBöszörményi 138H-4032DebrecenHungary Department of Economics The Islamia University of BahawalpurPakistan Department of Mining Engineering Indian Institute of Engineering Science and TechnologyShibpurP.O.711103Botanic GardenHowrahWest Bengal711103India Institute of Management and Organization Sciences Faculty of Economics and BusinessUniversity of DebrecenEgyetem Tér 14032DebrecenHungary School of Geographical Sciences Nanjing University of Information Science and TechnologyNanjing210044China Department of Physical Geography and Geoinformatics Faculty of Sciences and TechnologyUniversity of DebrecenEgyetem tér 14032DebrecenHungary Faculty of Economics and Business University of Debrecen4032DebrecenHungary Department of Trade and Finance Faculty of Economics and ManagementCzech University of Life SciencesPrague16500PragueCzech Republic Department of Agricultural Economics Faculty of AgricultureKahramanmaras SütçüImam UniversityTurkey Department of Agriculture Production Faculty of AgricultureKyambogo University P.O.B.1KyambogoKampalaUganda

Reducing environmental pollution is a critical goal in global environmental economics and economic *** European Union(EU)faces environmental challenges due to its development *** we present a comprehensive approach to assess the impact of carbon dioxide(CO_(2))emissions,energy consumption(EC),population structure(POP),economy(GDP),and policies on the environment within the EU using the environmental Kuznets curve(EKC).Our research reveals that between 1990 and 2019,the EU-27 experienced an increase of t1.18 million tonnes of oil equivalent(Mtoe)per year in energy consumption(p<0.05),while CO_(2)emissions decreased by 24.25 million tonnes(Mt)per year(p<0.05).The highest reduction in CO_(2)emissions occurred in Germany(7.52 Mt CO_(2)annually),and the lowest in Latvia(0.087 Mt CO_(2)annually).The empirical EKC analysis shows an inverted-U shaped relationship between GDP and CO_(2)emissions in the ***,a 1%increase in GDP results in a 0.705%increase in carbon emission,while a 1%increase in GDP2 leads to a 0.062%reduction in environmental pollution in the long run(p<0.01).These findings indicate that economic development within the EU has reached a stage where economic growth positively impacts the ***,this study provides insights into the effectiveness of environmental policies in mitigating degradation and promoting green growth in the EU 27 countries.

关键词： Invasion risk Climate change Adaptive genomic variation Genomic offset Habitat suitability

Simultaneous determination of nortriptyline hydrochloride and fluphenazine hydrochloride in microgram quantities from low dosage forms by liquid chromatography-UV detection

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Journal of Pharmaceutical Analysis 2012年第6期2卷 437-442页

作者： safwan Ashour Nuha Kattan Analytical Biochemistry Laboratory Department of Chemistry Faculty of Science University of Aleppo

A novel method for the simultaneous high-performance liquid chromatographic determi- nation of nortriptyline hydrochloride and fluphenazine hydrochloride was developed and validated. Fhivastatin sodium was used as internal standard. The determination was performed on a Hypersil Gold Cs column （250 mm × 4.6 mm i.d., 5 μm particle size） at 25 ℃; the mobile phase, consisting of a mixture of formic acid （0.1 M, pH 2.16）-methanol （33：67, v/v）, was delivered at a fow rate of 1.1 mL/min and detector wavelength at 251 rim. The retention time of nortriptyline, fluphenazine and fluvastatin was found to be 5.11, 8.05 and 11.38 min, respectively. Linearity ranges were 5.0-1350.0 and 10.0-1350.0 μg/ mL with limit of detection values of 0.72 and 0.31μg/mL, for nortriptyline and fluphenazine, respectively. Results of assay and recovery studies were statistically evaluated for its accuracy and precision. Correlation coefficients （r2） of the regression equations were greater than 0.999 in all cases. According to the validation results, the proposed method was found to be specific, accurate, precise and could be applied to the simultaneous quantitative analysis of nortriptyline and fluphenazine.

关键词： Nortriptylinehydrochloride Fluphenazinehydrochloride Liquid chromatographyPharmaceutical dosageform

Wound dehiscence with continuous versus interrupted mass closure of transverse incisions in children with absorbable suture:a randomized controlled trial

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World Journal of Pediatric Surgery 2019年第2期2卷 9-14页

作者： safwan Khan Muhammad Saleem Nabila Talat Department of Pediatric Surgery Armed Forces Hospital Southern RegionKhamis MushaytSaudi Arabia Department of Pediatric Surgery The Children's Hospital and The Institute of Child HealthLahorePakistan

Introduction Numerous meta-analyses done on adults suggest superiority of continuous mass closure technique,but any such study does not exist for the pediatric age *** results in adults cannot be applied to pediatrics because of numerous physiologic and anatomic *** This is a single-blinded,randomized controlled trial,1:1 parallel groups,that compares the frequency of dehiscence between the interrupted and continuous mass closure techniques for transverse incisions in pediatric *** age range was from birth to 12 *** sampled 350 patients undergoing emergency or elective exploratory laparotomies in our pediatric surgery *** randomization was used and only the patients remained blinded during the *** group was closed with interrupted mass closure(group A)and the other group with continuous mass closure technique(group B).We had to drop 50 patients for not meeting the inclusion *** The wound dehiscence rate for group A was 1.34%(4 patients)and for group B was 3.0%(9 patients).Significance was calculated usingχ^(2)(p<0.156).The global wound dehiscence rate was 4.34%(13 patients).The maximum number of patients dehisced on the fifth postoperative day,while the range was 4-11 *** only statistically significant confounding factor was wound classification(p<0.002).Discussion Statistically there is no significant difference between interrupted and continuous mass closures techniques in terms of wound *** dirty wounds are at a maximum risk of developing wound dehiscence irrespective of the technique *** need to strictly adhere to the basic principles of closure especially when dealing with dirty *** registration number TCTR20150318001.

关键词： wound closure interrupted

Thrombocytopenia after liver transplantation:should we care?

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World Journal of Gastroenterology 2018年第13期24卷 1386-1397页

作者： Kazuhiro Takahashi Shunji Nagai Mohamed safwan Chen Liang Nobuhiro Ohkohchi Department of Surgery Division of Gastroenterological and Hepatobiliary Surgery and Organ Transplantation University of TsukubaTsukubaIbaraki 3058575Japan Transplant and Hepatobiliary Surgery Henry Ford HospitalDetroitMl 48202United States

Transient thrombocytopenia is a common phenomenon after liver transplantation. After liver transplantation(LT), platelet count decreases and reaches a nadir on postoperative days 3-5, with an average reduction in platelet counts of 60%; platelet count recovers to preoperative levels approximately two weeks after LT. The putative mechanisms include haemodilution, decreased platelet production, increased sequestration, medications, infections, thrombosis, or combination of these processes. However, the precise mechanisms remain unclear. The role of platelets in liver transplantation has been highlighted in recent years, and particular attention has been given to their effects beyond hemostasis and thrombosis. Previous studies have demonstrated that perioperative thrombocytopenia causes poor graft regeneration, increases the incidence of postoperative morbidity, and deteriorates the graft and decreases patient survival in both the short and long term after liver transplantation. Platelet therapies to increase perioperative platelet counts, such as thrombopoietin, thrombopoietin receptor agonist, platelet transfusion, splenectomy, and intravenous immunoglobulin treatment might have a potential for improving graft survival, however clinical trials are lacking. Further studies are warranted to detect direct evidence on whether thrombocytopenia is the cause or result of poor-graft function and postoperative complications, and to determine who needs platelet therapies in order to prevent postoperative complications and thus improve post-transplant outcomes.

关键词： Thrombocytopenia Liver regeneration Platelet therapy Platelet Thrombopoietin receptor agonist Intravenous immunoglobulin treatment Liver transplantation

How Does COVID-19 Affect Demographic,Administrative,and Social Economic Domain?Empirical Evidence from an Emerging Economy

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International Journal of Mental Health Promotion 2022年第5期24卷 635-648页

作者： safwan Qadri Shixiang Chen Syed Usman Qadri School of Political Science and Public Administration Local Government Public Service Innovation Research CenterWuhan UniversityWuhan430072China Department of Management Science Time InstituteMultan60650Pakistan

Worldwide,the COVID-19 pandemic has had a signiﬁcant impact on social and economic conditions as well as mental and physical *** is considered in high ranks on Uncertainty Avoidance Index(UAI).The peo-ple of Pakistan have already faced numerous obstacles in terms of food and housing *** security,inﬂated prices of food items,andﬁnancial distress are the foremost vital challenges of Pakistan’s people during the *** study examines the people’s perception of social,economic,and psychological impact and explores the causes and trends of spreading the COVID-19 pandemic in Pakistan.A primary survey method was conducted to collect the data from all Punjab divisions via questionnaire,and 471 respondents wereﬁnally selected for data *** data collection instrument was a questionnaire,and the data analysis tool was ***,analysts,business professionals,economists,business faculty staff,and civil society are the study’s ***ﬁndings show that the overall social and economic life has been affected(82%of respondents agree)by the COVID-19 pandemic.60.5%of respondents manage their spending through salary(mean value=4.45),while 45%use savings(mean value=4.25).Moreover,Government support(mean value=3.95)plays a vital role in managing expenditure in this COVID-19 outbreak in ***,this study conﬁrms that the lock-down implementation measure(mean value=2.20)is not considered useful in reducing COVID-19 due to Pakistan’sﬁnancial and economic *** study concluded the social distance and testing measures are vital tools in reducing the COVID-19 pandemic in ***,the study established that micro-smart lockdown,increased COVID-19 testing kits,and adequate medical equipment in the Hospital of Pakistan are the key mechanism to control the ***,this study recommends that thorough long-term plan-ning be undertaken to mitigate the pandemic’s worst effects and develop a comprehensiv

关键词： COVID-19 health socioeconomic socio-demographic uncertainty avoidance index micro-smart lockdown

The Impact of Cultural Differences on Knowledge Sharing in Multicultural Project Teams

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The Impact of Cultural Differences on Knowledge Sharing in M...

作者： safwan Fahmi Mohammed Wahbas 山东大学

学位级别：硕士

Knowledge management is a critical factor for achieving a competitive advantage and creating value for the organization in the *** multicultural organization requires understanding of the behavior of knowledge sharing in multicultural project teams,because managing cultural diversity and sharing knowledge in multicultural teams is critical to project *** and managing cultural differences successfully offers many advantages to the project as well as the success of the *** the other hand,problems arising from cultural differences can cause waste of resources and delay in achieving project goals.　　This study investigated the impact of cultural differences on knowledge sharing in multicultural project *** the research questions,the impact of cultural differences factors were examined on knowledge sharing effectiveness through a mediator which is communication *** study is intended to fill the gap in the previous *** studies examined the effect of cultural differences on knowledge sharing by direct relationship or indirectly through mediators such as participation effectiveness,communication effectiveness and other mediators,but this study used the communication frequency as a mediator that links the cultural differences factors and the knowledge sharing effectiveness.　　The study found that the cultural differences factors that impact knowledge sharing through communication frequency are;power distance language and saving *** results of the study showed that reducing power distance,increasing individual's English competency and saving face positively impact communication *** study also showed that there is a positive relationship between communication frequency and social/task-related knowledge sharing *** study also showed that there is no statistical significance relationship between social-related knowledge sharing effectiveness and task-related knowledge sharing effect

关键词： Knowledge sharing Culture Communication frequency Power distance English competency Saving face

Hyper-Parameter Optimization of Semi-Supervised GANs Based-Sine Cosine Algorithm for Multimedia Datasets

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Computers, Materials & Continua 2022年第10期73卷 2169-2186页

作者： Anas Al-Ragehi Said Jadid Abdulkadir Amgad Muneer safwan Sadeq Qasem Al-Tashi Computer and Information Sciences Department Universiti Teknologi PETRONASSeri Iskandar32610PerakMalaysia Centre for Research in Data Science(CERDAS) Universiti Teknologi PETRONASSeri Iskandar32610Malaysia Mechanical Engineering Department Universiti Teknologi PETRONASSeri Iskandar32610PerakMalaysia Department of Imaging Physics The University of Texas MD Anderson Cancer CenterHoustonTXUSA University of Albaydha AlbaydhaYemen

Generative Adversarial Networks(GANs)are neural networks that allow models to learn deep representations without requiring a large amount of training ***-Supervised GAN Classifiers are a recent innovation in GANs,where GANs are used to classify generated images into real and fake and multiple classes,similar to a general multi-class ***,GANs have a sophisticated design that can be challenging to *** is because obtaining the proper set of parameters for all models-generator,discriminator,and classifier is *** a result,training a single GAN model for different datasets may not produce satisfactory ***,this study proposes an SGAN model(Semi-Supervised GAN Classifier).First,a baseline model was *** model was then enhanced by leveraging the Sine-Cosine Algorithm and Synthetic Minority Oversampling Technique(SMOTE).SMOTE was used to address class imbalances in the dataset,while Sine Cosine Algorithm(SCA)was used to optimize the weights of the classifier *** optimal set of hyperparameters(learning rate and batch size)were obtained using grid manual *** well-known benchmark datasets and a set of evaluation measures were used to validate the proposed *** proposed method was then compared against existing models,and the results on each dataset were recorded and demonstrated the effectiveness of the proposed *** proposed model successfully showed improved test accuracy scores of 1%,2%,15%,and 5%on benchmarking multimedia datasets;Modified National Institute of Standards and Technology(MNIST)digits,Fashion MNIST,Pneumonia Chest X-ray,and Facial Emotion Detection Dataset,respectively.

关键词： Generative adversarial networks semi-supervised generative adversarial network sine-cosine algorithm SMOTE principal component analysis grid search