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Animal models of human colorectal cancer:Current status, uses and limitations

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World Journal of Gastroenterology 2015年第41期21卷 11854-11861页

作者： vijay K mittal Jasneet Singh Bhullar Kumar Jayant Department of Surgery Providence Hospital and Medical Centers Department of Colorectal Surgery University of MinnesotaMN 55114 United States

AIM: To make orthotopic colon cancer murine modelsa more clearly understood subject. The orthotopic tumor models have been found to be more relevant in replicating the human disease process as compared to heterotopic models, many techniques for making orthotopic colorectal murine models have been ***: We evaluated the current literature for various reported orthotopic colon cancer models to understand their techniques, advantages and limitations. An extensive literature review was performed by searching the National Library of Medicine Database(Pub Med) using Me SH terms animal model; colon cancer; orthotopic model; murine model. Twenty studies related to colon cancer orthotopic xenograft model were evaluated in detail and discussed here. RESULTS: The detailed analysis of all relevant reports on orthotopic model showed tumor take rate between 42%-100%. While models using the enema technique and minimally invasive technique have reported development of tumor from mucosa with tumor take rate between 87%-100% with metastasis in 76%-90%.CONCLUSION: Over the years, the increased understanding of the murine models of human colon cancer has resulted in the development of various models. Each reported model has some limitations. These latest models have opened up new doors for continuing cancer research for not only understanding the colon cancer pathogenesis but also aid in the development of newer chemotherapeutic drugs as they mimic the human disease closely.

关键词： Murine model Colon cancer Colon cancer murine mode

Optimization of Cognitive Radio System Using Self-Learning Salp Swarm Algorithm

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Computers, Materials & Continua 2022年第2期70卷 3821-3835页

作者： Nitin mittal Harbinder Singh Vikas mittal Shubham Mahajan Amit Kant Pandit Mehedi Masud Mohammed Baz Mohamed Abouhawwash Department of Electronics&Communication Engineering Chandigarh UniversityMohali140413India School of VLSI Design and Embedded Systems National Institute of TechnologyKurukshetra136119India School of Electronics&Communication Engineering Shri Mata Vaishno Devi UniversityKatra182320India Department of Computer Science College of Computers and Information TechnologyTaif UniversityTaif21944Saudi Arabia Department of Computer Engineering College of Computer and Information TechnologyTaif UniversityTaif21994Saudi Arabia Department of Mathematics Faculty of ScienceMansoura UniversityMansoura35516Egypt Department of Computational Mathematics Scienceand Engineering(CMSE)Michigan State UniversityEast LansingMI48824USA

CognitiveRadio(CR)has been developed as an enabling technology that allows the unused or underused spectrum to be used dynamically to increase spectral *** improve the overall performance of the CR systemit is extremely important to adapt or reconfigure the *** Decision Engine is a major module in the CR-based system that not only includes radio monitoring and cognition functions but also responsible for parameter *** meta-heuristic algorithms offer numerous advantages compared to traditional mathematical approaches,the performance of these algorithms is investigated in order to design an efficient CR system that is able to adapt the transmitting parameters to effectively reduce power consumption,bit error rate and adjacent interference of the channel,while maximized secondary user ***-Learning Salp Swarm Algorithm(SLSSA)is a recent meta-heuristic algorithm that is the enhanced version of SSA inspired by the swarming behavior of *** this work,the parametric adaption of CR system is performed by SLSSA and the simulation results show that SLSSA has high accuracy,stability and outperforms other competitive algorithms formaximizing the throughput of secondary *** results obtained with SLSSA are also shown to be extremely satisfactory and need fewer iterations to converge compared to the competitive methods.

关键词： Cognitive radio meta-heuristic algorithm cognitive decision engine salp swarm algorithm

Single image defogging by gain gradient image filter

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Science China(Information Sciences) 2019年第7期62卷 225-227页

作者： Dilbag SINGH vijay KUMAR Computer Science and Engineering Department Apex Institute of Technology Chandigarh University Computer Science and Engineering Department Thapar Institute of Engineering and Technology

Dear editor,With the advancements in computer vision applications, the image defogging methods have received a lot of consideration. Defogging methods are extensively utilized in civil and military areas such as target detection, traffic surveillance,remote sensing. Therefore, the development of visibility restoration models has become a task of great interest and *** and Kumar [1] have proved that the dark

关键词： image Single image defogging by gain gradient image filter

VLSI scaling methods and low power CMOS buffer circuit

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Journal of Semiconductors 2013年第9期34卷 92-99页

作者： vijay Kumar Sharma Manisha Pattanaik Department of Information Technology ABV-Indian Institute of Information Technology & Management

Device scaling is an important part of the very large scale integration （VLSI） design to boost up the success path of VLSI industry, which results in denser and faster integration of the devices. As technology node moves towards the very deep submicron region, leakage current and circuit reliability become the key issues. Both are increasing with the new technology generation and affecting the performance of the overall logic circuit. The VLSI designers must keep the balance in power dissipation and the circuit＇s performance with scaling of the devices. In this paper, different scaling methods are studied first. These scaling methods are used to identify the effects of those scaling methods on the power dissipation and propagation delay of the CMOS buffer circuit. For mitigating the power dissipation in scaled devices, we have proposed a reliable leakage reduction low power transmission gate （LPTG） approach and tested it on complementary metal oxide semiconductor （CMOS） buffer circuit. All simulation results are taken on HSPICE tool with Berkeley predictive technology model （BPTM） BSIM4 bulk CMOS files. The LPTG CMOS buffer reduces 95.16% power dissipation with 84.20% improvement in figure of merit at 32 nm technology node. Various process, voltage and temperature variations are analyzed for proving the robustness of the proposed approach. Leakage current uncertainty decreases from 0.91 to 0.43 in the CMOS buffer circuit that causes large circuit reliability.

关键词： LPTG buffer power dissipation propagation delay scaling nanoscale CMOS figure of merit

New shape descriptor in the context of edge continuity

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CAAI Transactions on Intelligence Technology 2019年第2期4卷 101-109页

作者： Seba Susan Prachi Agrawal Minni mittal Srishti Bansal Department of Information Technology Delhi Technological University Bawana Road Delhi 110042 India

The object contour is a significant cue for identifying and categorising objects. The current work is motivated by indicative researches that attribute object contours to edge information. The spatial continuity exhibited by the edge pixels belonging to the object contour make these different from the noisy edge pixels belonging to the background clutter. In this study, the authors seek to quantify the object contour from a relative count of the adjacent edge pixels that are oriented in the four possible directions, and measure using exponential functions the continuity of each edge over the next adjacent pixel in that direction. The resulting computationally simple, low-dimensional feature set, called as ‘edge continuity features’, can successfully distinguish between object contours and at the same time discriminate intra-class contour variations, as proved by the high accuracies of object recognition achieved on a challenging subset of the Caltech-256 dataset. Grey-to-RGB template matching with City-block distance is implemented that makes the object recognition pipeline independent of the actual colour of the object, but at the same time incorporates colour edge information for discrimination. Comparison with the state-of-the-art validates the efficiency of the proposed approach.

关键词： contour objects approach

Synthesis of ethyl acetate by esterification of acetic acid with ethanol over a heteropolyacid on montmorillonite K10

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Journal of Natural Gas Chemistry 2010年第2期19卷 161-164页

作者： Hanumant Gurav vijay V.Bokade Catalysis Division National Chemical LaboratoryPune-411008India

In present work,liquid phase esterification of acetic acid with ethanol over dodecatungestophosphoric acid （DTPA） supported on K10 montmorillonite was systematically studied and optimization of process parameters was carried *** 20% m/m DTPA/K10 was found to be the optimum catalyst with 90% acetic acid conversion and 100% ethyl acetate *** study was also explored to see the feasibility of 20% m/m DTPA/K10 as a catalyst for the alkylation of acetic acid with other alcohols like methanol,iso-propanol and *** 20% m/m DTPA/K10 has shown increased activity with the increase in carbon number,at the same alcohol *** results are novel.

关键词： acetic acid ethanol heteropolyacid montmorillonite K10 ethyl acetate

Systematic study of kinematic and dynamic moments of inertia of superdeformed bands with NpNn scheme

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Chinese Physics C 2017年第8期41卷 101-107页

作者： Honey Sharma Neha Sharma H.M.mittal Dr.B.R.Ambedkar National Institute of Technology Jalandhar144011India CT Institute of Engineering Management and Technology Jalandhar144020India

The systematics of kinematic moment of inertia J and dynamic moment of inertia J of superdeformed（SD） bands in A -130, 150, 190 mass regions have been studied. We have obtained the values of J^（1） and J^（2）for all the SD bands observed in the A-130, 150, 190 mass regions by using the experimental intraband E2 transition energies. The result of this work includes the variation of J with the product of valence proton and neutron numbers（NpNn）. The phenomenon of band mixing has been observed in the A -130, 150 mass regions and band crossing has been observed in the A-190 mass region. The systematics also includes the variation of J with the product of valence proton and neutron numbers（NpNn）. Evidence of staggering behaviour has been observed in all three A-130, 150 and 190 mass regions. We present for the first time the variation of J^（1）and J^（2）of SD bands in the A-130, 150, 190 mass regions with NpNn.

关键词： kinematic moment of inertia j dynamic moment of inertia j NpYn scheme

Response of thermal source in a transversely isotropic thermoelastic half-space with mass diffusion by using a finite element method

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Chinese Physics B 2012年第8期21卷 307-313页

作者： Ibrahim A.Abbas Rajneesh Kumar vijay Chawla Department of Mathematics Faculty of Science and Arts-KhulaisKing Abdulaziz UniversityJeddahSaudi Arabia Department of Mathematics Faculty of ScienceSohag UniversitySohagEgypt Department of Mathematics Kurukshetra UniversityKurukshetra-136119HaryanaIndia

The two-dimensional problem of generalized thermoelastic diffusion material with thermal and diffusion relaxation times is investigated in the context of the Lord-Shulman theory. As an application of the problem, a particular type of thermal source is considered and the problem is solved numerically by using a finite element method. The components of displacement, stress, temperature distribution chemical potential and mass concentration are obtained. The resulting quantities are depicted graphically for a special model. An appreciable effect of relaxation times is observed on various resulting quantities.

关键词： thermoelastic diffusion thermal source finite element method relaxation time

Systematic study of rotational energy formulae for superdeformed bands in La and Ce isotopes

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Chinese Physics C 2017年第12期41卷 55-66页

作者： Honey Sharma H.M. mittal Dr. B.R. Ambedkar National Institute of Technology Jalandhar 144011 India

The experimental rotational spectra of superdeformed（SD） bands of 130La, 131Ce（1,2）, 132Ce（1,2,3） and133 Ce（1,2,3） in the A～130 mass region are systematically analyzed with the four parameter formula, power index formula, nuclear softness formula, and VMI model. It is observed that out of all the formulae, the four parameter formula suits best for the study of the 130La, 131Ce（1,2）, 132Ce（2,3） and 133Ce（1,2,3） SD bands. The four parameter formula works efficiently in determining the band head spin of the 130La, 131Ce（1,2） 132Ce（2,3） and 133Ce（1,2,3） SD bands. Good agreement is seen between the calculated and observed transition energies whenever the accurate spin is assigned. In 132Ce（1）, the power index formula is found to work better than the other three formulae. The dynamic moment of inertia is also calculated for all the formulae and its variation with the rotational frequency is investigated.

关键词： superdeformed bands four parameter formula power index formula nuclear softness formula VMI model