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Asian Journal of Andrology 2016年第6期18卷 950-951页

作者： mitchell s wachtel shengping Yang Brian J Morris Texas Tech University Health sciences Center Lubbock Texas USA school of Medical sciences University of Sydney Sydney New South Wales Australia

Dear Editor, We thank Dr. Kupferschmid for his interest in our study, which examined male circumcision （MC） and prostate cancer mortality〉2 Considerable strong evidence has been accumulated since 1951.3 Most of his references4-10 do not address MC and the risk of death from prostate cancer. That is a different question than MC and the risk of developing prostate cancer, which none of his references validly assess. One reference addressed bacterial colonization,6 not prostate cancer. Another7 concerned sexually transmitted infections and prostate cancer.

关键词： EPIDEMIOLOGY RIsK

Hepatoid carcinoma of the pancreas:a case report

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Chinese Medical Journal 2007年第20期120卷 1850-1852页

作者： LIU Chong-zhong HU san-yuan WANG Lei ZHI Xu-ting JIN Bin ZHU Min mitchell s. wachtel Eldo E. Frezza Department of General surgery Qilu Hospital Shan Dong University Jinan 250012 China Texas Tech University Health sciences Center Texas 79415 USA

In 1970, a gastric adenocarcinoma patient with increased alpha fetoprotein （AFP） in his serum and liver metastatic tumor was reported by Bourreilile et al. At that time, it was realized that a gastric adenocarcinoma could produce AFP. In 1985, Ishikura et al reported a hepatocellular carcinoma （HCC）-like differentiation in a primary gastric tumor and first proposed the conception of a ＂hepatoid carcinoma＂. subsequent documentation of this unique histopathologic feature has been made in other extrahepatic sites including the esophagus, papilla of Vater, colon, lung, gallbladder, adrenal gland, kidney, urinary bladder, ovary, uterus, vagina, testicle, and small intestine. However, the number of cases is very small. Hepatoid carcinoma is a primary extrahepatic neoplasm exhibiting features of hepatocellular carcinoma in terms of morphology, immunohistochemistry and biological behavior. But histopathologically it is very rare. Many but not all cases, present with an elevated serum AFP. Taking a wide view of various literatures it is evident that hepatoid carcinoma has mostly been found in the stomach and very rarely in the pancreas. To date, only eight cases of hepatoid carcinoma of the pancreas have been reported in the literature. We present a case of hepatoid carcinoma of the pancreas arising in an elderly man without evidence of residual disease eight months after local resection of the tumor.

关键词： hepatoid carcinoma pancreas alpha fetoprotein

Laparoscopic splenectomy： a 12-year single-center experience

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Chinese Medical Journal 2008年第8期121卷 766-768页

作者： CHEN Bo HU san-yuan WANG Lei WANG Ke-xin ZHANG Guang-yong ZHANG Hai-feng XUAN shi-jin mitchell s. wachtel Eldo E. Frezza Department of General surgery Qilu Hospital of Shangong University Jinan Shandong 250012 China Department of General surgery Linyi People's Hospital Linyi Shandong 276000 China Department of Pediatric surgery Jinan Central Hospital affiliated to Shandong University Jinan Shandong 250013 China Department of Pathology Texas Tech University Health Sciences Center Lubbock Texas 79415 USA Department of General surgery Texas Tech University Health Sciences Center Lubbock Texas 79415 USA

In 1991, Delaitre and Maignien performed the first splenectomy with a laparoscope. Laparoscopic splenectomy （Ls） is now an accepted alternative to open splenectomy, but questions still remain, such as the appropriate manner in which to position the patient, the best means of assuring hemostasis, and whether Ls can be performed in cases of splenomegaly.

关键词： splenectomy laparoscopy operative procedures

Loss expression of active fragile sites genes associated with the severity of breast epithelial abnormalities

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Chinese Medical Journal 2008年第20期121卷 1969-1974页

作者： WANG Tian-tian Eldo E Frezza MA Rong HU san-yuan LIU Chong-zhong ZHANG Guang-yong mitchell s. wachtel LU Xiao-mei FENG Jin-bo LU Cui-xia Department of General surgery Qilu Hospital Shandong University Jinan Shandong 250012 China Texas Tech University Health sciences Center Lubbock TX 79430 USA Department of Gynecology Jinan Central Hospital Jinan Shandong 250013 China Key Laboratory of Cardiovascular Remodeling and Function Research Chinese Ministry of Education and Chinese Ministry of Public Health Jinan Shandong 250012 China Division of statistics Shandong Center for Disease Control and Prevention Jinan Shandong 250012 China

Background WWOX and FHIT are two candidate tumor suppressor genes located in active fragile sites, the damage of which has been associated with the development of breast cancer. The association of the expression of these genes and the development of breast cancer has not been fully explored. We evaluated mRNA and protein expression of WWOX and FHIT in breast tissue with normal histological appearances, atypical ductal hyperplasia, ductal carcinoma in situ, and invasive cancer to see if a progressive decline in expression was present. Methods Reverse transcription-polymerase chain reaction and Western blotting were used to evaluate the specimens for mRNA and protein expression, including 28 specimens with normal tissue, 28 specimens with atypical ductal hyperplasia, 33 specimens with ductal carcinoma in situ, and 51 specimens with invasive ductal carcinoma. Results Compared with in situ and invasive cancer specimens, both normal and atypical hyperplasia specimens had greater rates of detectable mRNA （WWOX rate ratio=2.95, 95% CI 1.24-7.08; FHIT rate ratio=4.58, 95% CI 1.82-11.81） and Western blotting detectable protein （WWOX rate ratio=4.12, 95% CI 1.63-10.73; FHIT rate ratio=3.76, 95% CI 1.44-10.06）. For both proteins, differences between normal and atypical hyperplasia specimens and between in situ and invasive carcinoma specimens were explainable by chance （P 〉0.05 for each analysis）. Within each histological category, differences among fractions of specimens showed that FHIT and WWOX mRNA and protein expression were explainable by chance （P 〉0.05 for each analysis）. Conclusion Expression of FHIT and WWOX decreases along with breast tissue progress from a normal histological appearance to atypical ductal hyperplasia, in situ cancer, and the final invasive cancer.

关键词： breast neoplasms chromosome fragile sites tumor suppressor genes carcinogens

腹腔镜高选择性迷走神经切断术联合Nissen胃底折叠术:效果如何?——腹腔镜Nissen迷走神经切断术治疗胃食管返流

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中国微创外科杂志 2007年第6期7卷 561-563页

作者： Eldo E.Frezza sharmila Dissanaike mitchell s.wachtel 宫轲 Division of General surgery Department of Surgery and Minimally Invasive Surgical CenterTexas Tech University Health Sciences CenterLubbockTexasUSA. 北京世纪坛医院普外科北京100038

背景：Nissen胃底折叠术（Nissen fundoplication，NF）已不是治疗胃食管返流性疾病（gastroesophageal reflux disease，GERD）的唯一、有效的方法。对于能降低胃酸的手术方式来讲，如高选择性迷走神经切断术（highly selective vagot... 详细信息

背景：Nissen胃底折叠术（Nissen fundoplication，NF）已不是治疗胃食管返流性疾病（gastroesophageal reflux disease，GERD）的唯一、有效的方法。对于能降低胃酸的手术方式来讲，如高选择性迷走神经切断术（highly selective vagotomy，HsV），也不仅仅是一种辅助治疗方法。对高选择性迷走神经切断术联合Nissen胃底折叠术（Nissen fundoplication with highly selective vagotomy，NFHsV）治疗GERD的作用目前尚无完整的评价。方法：2003年6月～2005年6月8例女性病人接受NFHsV，8例均有6个月GERD病史，经药物治疗症状无缓解，有餐前痛、消化性溃疡或严重的胃炎。平均随访时间12个月，术前、术后进行烧心严重程度评分测定（heart burn severity score，Hss）。结果：平均手术时间110min，无手术并发症。1例术后须用质子泵抑制剂，术后经戒烟5个月后停药。8例术后症状和烧心严重程度评分测定有明显改善。结论：NFHsV是有效的联合手术方式，尚需要进一步的研究证实这一联合术式的完全有效性和安全性。

关键词：腹腔镜胃底折叠术胃食管返流性疾病消化性溃疡高选择迷走神经切断术

易用性与联通性——无线系统是今天对明天的回答

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A&s（安全&自动化） 2005年第9期 136-138页

作者： Alan wachtel

用户们对于产品的了解以及需求总是随着科技的飞速发展而改变。在美国家居网络市场（包括家用及办公用），无线网络系统的使用率已经达到52%。虽然其他国家在这方面比美国要落后，但是这种差距正在快速缩小。

关键词：无线系统易用性通性无线网络系统网络市场办公用使用率美国

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中国今后的政策方向：创新调整结构性平衡

国际商业技术 2011年第4期 28-31页

作者： Paul wachtel[美] 单佳灵（全译）美国纽约大学stern商学院

全球普遍存在“经常账户失衡”问题，美国的赤字和中国的过多盈余也是这个问题的表现，作为世界两大经济体，美国和中国必须采取合理的国内储蓄及投资政策，以改善经常账户的失衡，并对中国提出了金融创新、提升公共服务等建议。

关键词：经常账户失衡赤字盈余调整平衡金融创新

2015年辽宁省阜新蒙古族自治县塔尺营子遗址试掘报告

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边疆考古研究 2019年第1期 1-52页

作者：滕铭予吉迪苏军强 Ido wachtel Ahiad OVADIA Ofer MARDER 涂栋栋 Roi sHAVIT 马志坤陈秋荷杨晓燕 Chris J.stevens Dorian Q.Fuller 王震王争王欢向明文崔嵩姚崇 Hagit PRIGOJIN Tiki sTEINER Keren NEBENHAUs 刘西平吉林大学长春130012 耶路撒冷希伯来大学耶路撒冷91000 辽宁省文物考古研究所沈阳110003 本·古里安大学贝尔谢巴84001 西北大学文化遗产学院文化遗产研究与保护技术教育部重点实验室西安710069 中国科学院地理科学与资源研究所中国科学院陆地表层格局与模拟院重点实验室北京100101 中国科学院大学北京100049 中国科学院青藏高原研究所中国科学院高寒生态重点实验室北京100101 中国科学院青藏高原地球科学卓越创新中心北京100101 英国伦敦大学院大学考古研究所伦敦WC1H0AL 阜新市文物管理办公室阜蒙县博物馆美国匹兹堡大学

自2012年起,吉林大学和辽宁省文物考古研究所合作开展了"中国东北地区农业与定居的起源"项目,在阜新查海遗址的东部地区进行了区域性田野考古调查[1]。2015年,为了进一步了解阜新地区新石器时代不同阶段古代居民的经济生活,在前期进行... 详细信息

自2012年起,吉林大学和辽宁省文物考古研究所合作开展了"中国东北地区农业与定居的起源"项目,在阜新查海遗址的东部地区进行了区域性田野考古调查[1]。2015年,为了进一步了解阜新地区新石器时代不同阶段古代居民的经济生活,在前期进行的区域性田野考古调查工作的基础上,选择了贾家沟西遗址(田野调查时遗址编号为12D56)和塔尺营子遗址(田野调查时遗址编号为12D16)进行了试掘。本文是塔尺营子遗址的试掘报告。

关键词：兴隆洼文化植硅体分析附加堆纹阜新蒙古族自治县