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High-density SNP-based genetic maps for the parents of an outcrossed and a selfed tetraploid garden rose cross, inferred from admixed progeny using the 68k rose SNP array

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Horticulture Research 2016年第1期3卷 68-75页

作者： mirjana vukosavljev Paul Arens Roeland E Voorrips Wendy P C van't Westende G D Esselink Peter M Bourke Peter Cox W Eric van de Weg Richard G F Visser Chris Maliepaard Marinus J M Smulders Wageningen UR Plant Breeding Wageningen University&ResearchWageningenNL-6700 AJThe Netherlands Roath BV EindhovenThe Netherlands Pheno Geno Roses D.O.O.Bulevar oslobođenja 65a 21000 Novi SadSerbia

Dense genetic maps create a base for QTL analysis of important traits and future implementation of marker-assisted *** tetraploid rose,the existing linkage maps include<300 markers to cover 28 linkage groups(4 homologous sets of 7 chromosomes).Here we used the 68k WagRhSNP Axiom single-nucleotide polymorphism(SNP)array for rose,in combination with SNP dosage calling at the tetraploid level,to genotype offspring from the garden rose cultivar‘Red New Dawn’.The offspring proved to be not from a single bi-parental *** rose breeding,crosses with unintended parents occur *** developed a strategy to separate progeny into putative populations,even while one of the parents was unknown,using principle component analysis on pairwise genetic distances based on sets of selected SNP markers that were homozygous,and therefore uninformative for one *** of the inferred populations was consistent with self-fertilization of‘Red New Dawn’.Subsequently,linkage maps were generated for a bi-parental and a self-pollinated population with‘Red New Dawn’as the common maternal *** densest map,for the selfed parent,had 1929 SNP markers on 25 linkage groups,covering 1765.5 cM at an average marker distance of 0.9 *** with the strawberry(Fragaria vesca)genome was *** ICM1 corresponded to *** pseudochromosome 7(Fv7),ICM4 to Fv4,ICM5 to Fv3,ICM6 to Fv2 and ICM7 to *** ICM2 corresponded to parts of *** pseudochromosomes 1 and 6,whereas ICM3 is syntenic to the remainder of Fv6.

关键词： breeding linkage dosage

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REGULARITY OF SOLUTIONS TO NONLINEAR TIME FRACTIONAL DIFFERENTIAL EQUATION

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Acta Mathematica Scientia 2013年第6期33卷 1721-1735页

作者： mirjana STOJANOVI Department of Mathematics and Informatics University of Novi Sad

We find an upper viscosity solution and give a proof of the existence-uniqueness in the space C^∞（t∈（0,∞）;H2^s＋2（R^n））∩C^0（t∈[0,∞）;H^s（R^n））,s∈R,to the nonlinear time fractional equation of distributed order with spatial Laplace operator subject to the Cauchy conditions ∫0^2p（β）D＊^βu（x,t）dβ=△xu（x,t）＋f（t,u（t,x））,t≥0,x∈R^n,u（0,x）=φ（x）,ut（0,x）=ψ（x）,（0.1） where △xis the spatial Laplace operator,D＊^β is the operator of fractional differentiation in the Caputo sense and the force term F satisfies the Assumption 1 on the regularity and growth. For the weight function we take a positive-linear combination of delta distributions concentrated at points of interval （0, 2）, i.e., p（β） =m∑k=1bkδ（β-βk）,0〈βk〈2,bk〉0,k=1,2,…,*** regularity of the solution is established in the framework of the space C^∞（t∈（0,∞）;C^∞（R^n））∩C^0（t∈[0,∞）;C^∞（R^n））when the initial data belong to the Sobolev space H2^8（R^n）,s∈R.

关键词： nonlinear time-fractional equations of distributed order existence-uniqueness theorems viscosity solutions regularity result

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Nonlinear Parabolic Equations with Singularities in Colombeau Vector Spaces

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Acta Mathematica Sinica,English Series 2006年第2期22卷 393-406页

作者： mirjana STOJANOVI Department of Mathematics and Informatics Faculty of Science University of Novi Sad

We consider nonlinear parabolic equations with nonlinear non-Lipschitz＇s term and singular initial data like Dirac measure, its derivatives and powers. We prove existence-uniqueness theorems in Colombeau vector space yC^1,W^2,2（[0,T）,R^n）,n ≤ 3. Due to high singularity in a case of parabolic equation with nonlinear conservative term we employ the regularized derivative for the conservative term, in order to obtain the global existence-uniqueness result in Colombeau vector space yC^1,L^2（[0,T）,R^n）,n≤ 3.

关键词： nonlinear parabolic equation parabolic equation with nonlinear conservative term singular initial data Colombeau vector spaces regularized derivatives existence-uniqueness theorems

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Isotropic Affine Spheres

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Acta Mathematica Sinica,English Series 2012年第10期28卷 1955-1972页

作者： Olivier BIREMBAUX mirjana DJORI Université Lille Nord de France F-59000 Lille Laboratoire de Mathématiques et ses Applications de Valenciennes Université de Valenciennes et du Hainaut Cambrésis Faculty of Mathematics University of Belgrade Studentski trg 16

In this paper, we study affine spheres which are isotropic and we obtain a complete clas- sification. In particular, we show that all such afline spheres are hyperbolic afiine spheres, isometric with SL（3, R）/SO（3... 详细信息

关键词： Afline sphere isotropic submanifold symmetric space

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Long term sediment transport simulation of the Danube,Sava,and Tisa rivers

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International Journal of Sediment Research 2020年第5期35卷 550-561页

作者： mirjana Horvat Zoltan Horvat University of Novi Sad Faculty of Civil Engineering Subotica

The aim of this paper is to evaluate a newly developed one dimensional unsteady flow,sediment transport and bed evolution model for a looped river network through a long term simulation of a reallife *** model was assessed by verifying it for the Danube,Tisa,and Sava rivers in Serbia for a five year time *** total length of the modeled domain was 741.94 km from which 486.48 km is the length of the modeled Danube River reach,132.50 km the modeled section of the Sava and 122.96 km the length of the modeled Tisa River *** simulated domain included smaller tributaries such as the Kolubara,Mlava,Nera,Pek,Porecka,Tamis,and Great Morava *** to the size of the domain that was included in the model,the work also includes extensive research regarding the available measurements,issues with measurement errors,and suggestions on overcoming incomplete measurements by developing different types of *** attained results were analyzed by comparing the simulation results with measured water levels,discharges,and suspended sediment *** implemented evaluation of the results confirmed the developed model's reliability.

关键词： 1-D sediment transport Looped river network Long term simulation Calibration Verification

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Protective effects of exogenous gangliosides on ROS-induced changes in human spermatozoa

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Asian Journal of Andrology 2013年第3期15卷 375-381页

作者： mirjana Gavella Vaskresenija Lipovac Reproductive Biochemistry and Cell Metabolism Unit Institute of Clinical Chemistry and Laboratory Medicine Merkur University Hospital Zagreb 10000 Croatia

This article summarizes the available evidence on the efficacy of gangliosides to reduce the degree of reactive oxygen species （ROS）-mediated damage. The antioxidative efficacy of exogenous gangliosides in protecting different cells encouraged us to examine their ability to protect human spermatozoa. Gangliosides are sialic acid-containing glycosphingolipids with strong amphiphilic character due to the bulky headgroup made of several sugar rings with sialic acid residues and the double-tailed hydrophobic lipid moiety. The amphiphilicity of gangliosides allows them to exist as micelles in aqueous media when they are present at a concentration above their critical micellar concentration. The protective effect of ganglioside micelles on spermatozoa is believed to stem from their ability to scavenge free radicals and prevent their damaging effects, In our study, we particularly focused our attention on the protective effect of ganglioside micelles on DNA in human spermatozoa exposed to cryopreservation. The results indicate that ganglioside micelles can modulate the hydrophobic properties of the sperm membrane to increase tolerance to DNA fragmentation, thus protecting the DNA from cryopreservation-induced damage. Further actions of ganglioside micelles, which were documented by biochemical and biophysical studies, included （i） the modulation of superoxide anion generation by increasing the diffusion barrier for membrane events responsible for signal translocation to the interior of the cell; （ii） the inhibition of iron-catalysed hydroxyl radical formation due to the iron chelation potential of gangliosides; and （iii） inhibition of hydrogen peroxide diffusion across the sperm membrane.

关键词： exogenous gangliosides oxidative stress protection spermatozoa

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Understorey species distinguish late successional and ancient forests after decades of minimum human intervention: A case study from Slovenia

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Forest Ecosystems 2023年第1期10卷 92-101页

作者： mirjana Sipek Tim Ravnjak Nina Sajna University of Maribor Faculty of Natural Sciences and MathematicsKoroska c.1602000MariborSlovenia

The main species composition drivers in temperate deciduous forests are environmental conditions, a stand?s age and the site history, e.g., the succession stage and past land use, as well as disturbance regime and current management. We compared plant species diversity and composition in late successional and ancient forests, cooccurring on the same small river island applying species accumulation curves and nonmetric multidimensional scaling, respectively. Given the island?s geomorphological characteristics, we expected these to be very similar before human intervention in the past. The forests experienced differing disturbance regimes in the past, while over the last 30 years, human intervention has been the same and reduced to a minimum. The ancient forest in this study had two major characteristics defining it as old, mature forest: continuity of presence for more than 200years and specific composition. The late successional forest experienced major disturbance in the 20th century and was allowed natural regeneration by bordering on the ancient forest, representing a potential species pool,and by decades of minimum human intervention. Our results showed that, even though there was no difference in species richness, we could still detect differences between the forests, particularly in the abundance and species composition of the understorey, among which geophytes had the most indicative importance. To make our results useful on a broader scale, we composed from the literature a species list of plants indicative for ancient forest and tested its application. These results are important for distinguishing between old and mature secondary stands and particularly for identifying old forest stands, which should be conserved and, in the case of fragmented landscapes, included in a network connecting forest fragments.

关键词： Forest community Successional forest Indicator plants Plant diversity Understorey Geophytes

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Inducing neuronal regeneration and differentiation via the BDNF/ TrkB signaling pathway: a key target against neurodegenerative diseases?

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Neural Regeneration Research 2024年第3期19卷 495-496页

作者： mirjana Antonijevic Patrick Dallemagne Christophe Rochais Normandie University UNICAENCERMNCaenFrance

Brain-derived neurotrophic factor(BDNF)is one of the neurotrophins,a specific polypeptide growth factor,which plays a crucial role in the proliferation,differentiation,survival,and death of neurons and non-neuronal *** is not only essential to maintain the balance between death on one side and survival of neurons on the other,but also it mediates additional higher-order activities such as learning,memory,and *** is initially synthesized as a precursor protein,proBDNF,that can be secreted as it is or it can be cleaved intracellularly by furin and proconvertases,or extracellularly by extracellular proteases such as matrix metalloprotease-9 and matrix metalloprotease-2,or plasmin to give mature BDNF.

关键词： death diseases degenerative

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Characterization of Totally Geodesic Totally Real 3-dimensional Submanifolds in the 6-sphere

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Acta Mathematica Sinica,English Series 2006年第5期22卷 1557-1564页

作者： Miroslava ANTIC mirjana DJORIC Luc VRANCKEN Faculty of Mathematics University of BelgradeStudentski trg 16 pb. 550 11000 Belgrade Serbia and Montenegro LAMATH ISTV2 Université de Valenciennes Campus du Mont Houy59313 Valenciennes Cedex 9 France

In this paper, we study Lagrangian submanifolds of the nearly Kaehler 6-sphere. We derive a pinching result for the Ricci curvature of such submanifolds thus providing a characterisation of the totally geodesic subman... 详细信息

关键词： Ricci curvature totally real submanifold nearly Kaehler 6-sphere totally geodesic submanifold

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Land use optimization for sustainable development of mountain regions of western Serbia

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Journal of Mountain Science 2018年第7期15卷 1471-1480页

作者： Tijana VULEVIC mirjana TODOSIJEVIC Nada DRAGOVIC Miodrag ZLATIC University of Belgrade Faculty of Forestry Kneza Viseslava 1 11000 Belgrade Serbia

This study analyses the possibilities for optimal land use structure in mountainous areas of rural Serbia, which is faced with problems such as unfavorable terrain characteristics and inadequate land use patterns causing economic underdevelopment and increasing population migration. In the case of a small privately owned farm in Western Serbia, optimal land use pattern is determined using the linear programming model. The objective function-cost-effectiveness or soil erosion reduction, as well as constraints, are formulated using the benefit-cost ratio(BCR) for a 15-year production period and soil losses data calculated using the Universal Soil Loss Equation(USLE). The best results are achieved using the scenario with the aim to minimize soil erosion, considering the BCR in the constraints. This scenario is proposed since it was registered that the benefit for landowners would increase by five times, while the losses of land would decline about 80%. The sensitivity analysis of investments is performed to check whether the price variation affects the cost-effectiveness of proposed land use. Results show that market changes(nine cases are considered) do not lead to significant changes in land use allocation. Proposed land use pattern improves the environmental condition, strengthens the rural economy and thus offers the greatest potential for sustainable development of mountainous rural areas.

关键词： Cost-benefit analysis Linear programming Land use optimization Mountain region Soil erosion

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