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UAV-Assisted Dynamic Avatar Task Migration for Vehicular Metaverse Services: A Multi-Agent Deep Reinforcement Learning Approach

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IEEE/CAA Journal of Automatica Sinica 2024年第2期11卷 430-445页

作者： Jiawen Kang Junlong Chen minrui xu Zehui Xiong Yutao Jiao Luchao Han Dusit Niyato Yongju Tong Shengli Xie IEEE School of Automation Guangdong University of TechnologyGuangzhou 510006China 111 Center for Intelligent Batch Manufacturing based on IoT Technology Guangzhou 510006China Key Laboratory of Intelligent Information Processing and System Integration of IoT Ministry of EducationGuangzhou 510006China School of Computer Science and Engineering Nanyang Technological UniversitySingaporeSingapore Pillar of Information Systems Technology and Design Singapore University of Technology and DesignSingaporeSingapore College of Communication Engineering Army Engineering University of PLANanjing 210007China National Natural Science Foundation of China Beijing 100085China Key Laboratory of Intelligent Detection and IoT in Manufacturing Ministry of EducationGuangzhou 510006China Guangdong Key Laboratory of IoT Information Technology Guangzhou 510006China

Avatars, as promising digital representations and service assistants of users in Metaverses, can enable drivers and passengers to immerse themselves in 3D virtual services and spaces of UAV-assisted vehicular Metaverses. However, avatar tasks include a multitude of human-to-avatar and avatar-to-avatar interactive applications, e.g., augmented reality navigation,which consumes intensive computing resources. It is inefficient and impractical for vehicles to process avatar tasks locally. Fortunately, migrating avatar tasks to the nearest roadside units(RSU)or unmanned aerial vehicles(UAV) for execution is a promising solution to decrease computation overhead and reduce task processing latency, while the high mobility of vehicles brings challenges for vehicles to independently perform avatar migration decisions depending on current and future vehicle status. To address these challenges, in this paper, we propose a novel avatar task migration system based on multi-agent deep reinforcement learning(MADRL) to execute immersive vehicular avatar tasks dynamically. Specifically, we first formulate the problem of avatar task migration from vehicles to RSUs/UAVs as a partially observable Markov decision process that can be solved by MADRL algorithms. We then design the multi-agent proximal policy optimization(MAPPO) approach as the MADRL algorithm for the avatar task migration problem. To overcome slow convergence resulting from the curse of dimensionality and non-stationary issues caused by shared parameters in MAPPO, we further propose a transformer-based MAPPO approach via sequential decision-making models for the efficient representation of relationships among agents. Finally, to motivate terrestrial or non-terrestrial edge servers(e.g., RSUs or UAVs) to share computation resources and ensure traceability of the sharing records, we apply smart contracts and blockchain technologies to achieve secure sharing management. Numerical results demonstrate that the proposed approach

关键词： Avatar blockchain metaverses multi-agent deep reinforcement learning transformer UAVs

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UAV-Assisted Dynamic Avatar Task Migration for Vehicular Metaverse Services: A Multi-Agent Deep Reinforcement Learning Approach

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自动化学报（英文版） 2024年第2期

作者： Jiawen Kang Junlong Chen minrui xu Zehui Xiong Yutao Jiao Luchao Han Dusit Niyato Yongju Tong Shengli Xie

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“疾控中心+基层医疗卫生机构”医防联合体建设探索与思考

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中国公共卫生管理 2024年第3期40卷 355-360页

作者：史宏李涌黄定中潘英姿陈丹强德仁许敏锐常州市武进区疾病预防控制中心江苏常州213164 常州市武进区前黄镇寨桥卫生院

为了逐步推进公共卫生资源下沉,建立公共卫生机构和基层医疗卫生机构协同发展机制,常州市武进区疾病预防控制中心和前黄镇寨桥卫生院探索开展了江苏省首家“疾控中心+基层医疗机构”医防联合体建设。通过采取“医防联合”工作机制、“1+... 详细信息

为了逐步推进公共卫生资源下沉,建立公共卫生机构和基层医疗卫生机构协同发展机制,常州市武进区疾病预防控制中心和前黄镇寨桥卫生院探索开展了江苏省首家“疾控中心+基层医疗机构”医防联合体建设。通过采取“医防联合”工作机制、“1+1+N”队伍体系、“主动服务、技术下沉”服务模式、“双向联动”的反馈机制、“医防融合”一体化服务模式等举措,推动疾病预防控制中心主动融入医共体建设发展。医防联合体项目开展以来,整个机制运转流畅、项目实施效果显著、医防融合项目有序开展。在不断融合的基础上,逐渐形成了一套可复制、可推广的新模式,为落实疾病三级预防和连续管理、提升区域公共卫生服务能力、促进全区卫生事业高质量可持续发展提供了新思路。

关键词：医防融合疾病预防控制中心基层医疗卫生机构医共体

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代谢综合征及其组分与脑卒中发病关系的前瞻性队列研究

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南京医科大学学报（自然科学版） 2024年第9期44卷 1238-1245页

作者：孔晓玲史宏潘英姿许敏锐石素逸宗菁闫于飘杨佳成张锡炳杭栋刘逸舒强德仁常州市武进区疾病预防控制中心慢病科江苏常州213164 南京医科大学公共卫生学院江苏南京211166

目的:探讨代谢综合征(metabolic syndrome,MS)及其组分与脑卒中发病风险的关联。方法:采用前瞻性队列研究方法比较脑卒中发病与未发病人群人口统计学信息、行为生活方式、饮食习惯、疾病史、MS相关指标之间差异。采用Cox比例风险回归模... 详细信息

目的:探讨代谢综合征(metabolic syndrome,MS)及其组分与脑卒中发病风险的关联。方法:采用前瞻性队列研究方法比较脑卒中发病与未发病人群人口统计学信息、行为生活方式、饮食习惯、疾病史、MS相关指标之间差异。采用Cox比例风险回归模型分析MS组分及其交互作用与脑卒中发病的关联。结果:脑卒中发病人群的年龄、腰围(waist circumference,WC)、体重指数(body mass index,BMI)、血压(blood pressure,BP)、总胆固醇(total cholesterol,TC)、甘油三酯(triglycerides,TG)、空腹血糖(fasting plasma glucose,FPG)值均高于未发病人群。校正混杂因素后,MS、WC、TG、BP、FPG均与脑卒中发病风险增加相关,其中BP异常与脑卒中发病的联系最强。WC、TG、BP、FPG两两之间均不存在相乘交互作用及相加交互作用。结论:MS与脑卒中发病风险增加相关。WC、TG、BP和FPG是脑卒中发病的独立危险因素。BP异常对脑卒中发病的影响最大。

关键词：脑卒中代谢综合征队列研究交互作用

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Post-Marketing Surveillance of Adverse Events Following Immunization with Haemophilus Influenzae Type b Conjugate Vaccine — China, 2010–2021

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China CDC weekly 2024年第33期6卷 834-840页

作者： minrui Ren Keli Li Yan Li Chunxiang Fan Yuyang xu Lina Zhang Yuan Li Lei Cao Wenzhou Yu Zundong Yin National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases(NITFID) National Immunization ProgrammeChinese Center for Disease Control and PreventionBeijingChina Department of Expanded Programme on Immunization Hangzhou Center for Disease Control and PreventionHangzhou CityZhejiang ProvinceChina

Introduction The Haemophilus influenzae type b(Hib)conjugate vaccine is widely administered in *** We extracted data on Hib vaccine doses administered and adverse events following immunization(AEFI)reported between 2010 and 2021 from the Chinese National Immunization Information System(CNIIS).A descriptive analysis was conducted to examine the characteristics and incidence rates of AEFI with the Hib *** In China,between 2010 and 2021,a total of 52,910 AEFIs with the Hib vaccine were reported,resulting in an overall AEFI reporting rate of 38.10 per 100,000 ***(typically minor)and rare(potentially serious)vaccine reactions occurred at rates of 34.71 and 2.78 per 100,000 doses,*** the common vaccine reactions,the incidences of fever(axillary temperature≥38.6℃),injection site redness and swelling(>2.5 cm in diameter),and injection site induration(>2.5 cm in diameter)were 11.93,9.69,and 3.38 per 100,000 doses,*** vaccine reactions included anaphylactic rash,angioedema,and febrile convulsion with reported incidences of 2.42,0.10,and 0.05 per 100,000 doses,*** incidence of serious rare vaccine reactions was 0.16 per 100,000 *** The reported incidence of AEFI with the Hib vaccine was low,with the occurrence of serious rare adverse reactions also being markedly low throughout the period 2010–2021 in China.

关键词： doses markedly injection

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The bacterial effector SidN/Lpg1083 promotes cell death by targeting Lamin-B2

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Journal of Molecular Cell Biology 2023年第5期15卷 52-65页

作者： Jiajia Gao Wenwen xu Feng Tang minrui xu Qin Zhou Xingyuan Yang Nannan Zhang Jinming Ma Qi Yang Xiaofang Chen Ximing Qin Honghua Ge Institute of Health Sciences and Technology Institutes of Material Science and Information TechnologyAnhui UniversityHefei 230601China School of Life Sciences Anhui UniversityHefei 230601China Information Materials and Intelligent Sensing Laboratory of Anhui Province Anhui UniversityHefei 230601China

To facilitate survival,replication,and dissemination,the intracellular pathogen Legionella pneumophila relies on its unique type IVB secretion system(T4SS)to deliver over 330 effectors to hĳack host cell pathways in a spatiotemporal *** effectors and their host targets are largely unexplored due to their low sequence identity to the known proteins and functional *** T4SS effector SidN(Lpg1083)is secreted into host cells during the late infection ***,to the best of our knowledge,the molecular characterization of SidN has not been ***,we identified SidN as a nuclear envelope-localized *** structure adopts a novel fold,and the N-terminal domain is crucial for its specific subcellular ***,we found that SidN is transported by eukaryotic karyopherin Importin-13 into the nucleus,where it attaches to the N-terminal region of Lamin-B2 to interfere with the integrity of the nuclear envelope,causing nuclear membrane disruption and eventually cell *** work provides new insights into the structure and function of an *** effector protein,and suggests a potential strategy utilized by the pathogen to promote host cell death and then escape from the host for secondary infection.

关键词： Lamin-B2 Importin-13 cell death Legionella pneumophila SidN Lpg1083 T4SS effector

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多绕组电压互感器二次负荷配置原则及其工程应用

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高电压技术 2015年第1期41卷 202-208页

作者：杨世海周赣周峰姚勋徐敏锐江苏省电力公司电力科学研究院南京211103 国家电网公司电能计量重点实验室南京210019 东南大学电气工程学院南京210096 中国电力科学研究院武汉430074

针对更换新型二次装置造成电压互感器轻载现象严重，进而引起实际运行时误差正偏较大的现象，基于多绕组电压互感器的电磁模型，详细分析了计量和保护绕组二次负荷额定值及实际值对计量误差的影响机理，根据理论和试验结果制定了多绕组... 详细信息

针对更换新型二次装置造成电压互感器轻载现象严重，进而引起实际运行时误差正偏较大的现象，基于多绕组电压互感器的电磁模型，详细分析了计量和保护绕组二次负荷额定值及实际值对计量误差的影响机理，根据理论和试验结果制定了多绕组二次负荷的配置原则，并将其应用于江苏电网电厂上网关口计量装置改造工程中。改造工程的检测结果表明，电压互感器的误差正向偏移现象得到了明显改善，运行计量精度代数平均值仅为0．00078％，且90％以上电压互感器的运行误差被控制在-0．05％～O．05％区间内，互感器设计的最佳误差特性点得到了应用。

关键词：多绕组电压互感器:二次负荷轻载计量误差电磁模型

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A Hybrid Quantum Clone Evolutionary Algorithm-Based Scheduling Optimization in a Networked Learning Control System

A Hybrid Quantum Clone Evolutionary Algorithm-Based Scheduli...

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2010 Chinese Control and Decision Conference

作者： Lijun xu,minrui Fei Shanghai Key Laboratory of Power Station Automation Technology,Shanghai University,Shanghai 200072,China.

＜正＞Control and network performance rely on the design of system architecture,control algorithm and scheduling of network *** this paper,a two-layer networked learning control system（NLCS） architecture is introduced, achieving better control performance,better interference rejection and increasing the adaptability to varying *** establish a multi-objective optimization（MOO） based on Hybrid Quantum Clone Evolutionary Algorithm（HQCEA） with rules of expert knowledge describing for the control performance and bandwidth requirements in the two-layer NLCS to dynamically allocate bandwidth of each control loop,aiming at realizing maximization of control performance and minimization of bandwidth *** theoretical results are confirmed by the simulations of the algorithm.

关键词： NLCS HQCEA Multi-objective optimization Bandwidth

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Heme regulates expression of exocrine peptidase precursor genes via the Nrf2/Bach1-MafK pathway in zebrafish

Heme regulates expression of exocrine peptidase precursor ge...

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2012全国发育生物学大会

作者： Shuqing Zhang~*,minrui xu~*,Han Wang Center for Circadian Clocks,Medical College,Soochow University,199 Renai,SIP,Suzhou,Jiangsu 215123

Defects in the enzymes involved in the heme biosynthetic pathway result in a group of human diseases known as porphyrias or ***,we established a UROD-deficient zebrafish(yquem/urod) as a model for studying human hepatoerythropoietic porphyria(HEP) and porphyria cutanea tarda(PCT),and reported downregulation of six exocrine peptidase precursor genes,carboxypeptidase A(cpa),trypsin precursor(try),trypsin like(tryl),chymotrypsinogen B1 (ctrb1),chymotrypsinogen I like(ctrl1),and elastase 2 like(ela2l),in yquem/urod(-/-).However,molecular genetic mechanisms underlying heme regulation of these exocrine peptidase precursor genes are still *** we show that overexpression of bach1 and knockdown of nrf2 all result in downregulation of these exocrine peptidase precursor genes in zebrafish,whereas overexpression of nrf2 and knockdown of bach1 all result in upregulation of these exocrine peptidase precursor genes in *** protein can recognize and bind the Maf recognition element(MARE) in the regulatory regions of these exocrine *** vitro luciferase assays demonstrate that heme activates these zymogens in a dosage-dependent manner,and the Bach1:MafK heterodimer represses these zymogens,whilst the Nrf2:MafK heterodimer activates ***,chromatin immunoprecipitation assays show that heme triggers replacing Bach1 with Nrf2 within the MafK-occupied MARE sites in the regulatory regions of these zymogens,and particularly in heme-deficient porphyria,the repressing *** heterodimer dominates,which can be switched to the activating Nrf2:MafK heterodimer by hemin treatment. Conclusions:These findings provide novel insights into heme deficiency pathogenesis,and new approaches to diagnosing and treatment of patients with porphyria or pancreatic diseases.

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基于空心线圈互感系数自校验原理的大电流校验系统

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高电压技术 2014年第8期40卷 2335-2342页

作者：李振华王忠东卢树峰徐敏锐陈刚陈霄华中科技大学强电磁工程与新技术国家重点实验室武汉430074 江苏省电力公司电力科学研究院南京211103

对保护用电流互感器在大电流时的性能进行校验时一般采用含铁芯的电磁式互感器作为标准。但电流较大时,电磁式互感器铁芯体积大、制造困难,且剩磁现象严重,导致其误差变大。为此,提出了一种基于空心线圈互感系数自校验原理的交流大电流... 详细信息

对保护用电流互感器在大电流时的性能进行校验时一般采用含铁芯的电磁式互感器作为标准。但电流较大时,电磁式互感器铁芯体积大、制造困难,且剩磁现象严重,导致其误差变大。为此,提出了一种基于空心线圈互感系数自校验原理的交流大电流校验系统。在小电流时,该系统利用铁芯线圈的输出来校正空心线圈的安装等外界因素可能造成的误差。由于空心线圈的线性度好,校准后的空心线圈可作为大电流校验时的电流标准。空心线圈的输出需要积分还原,采用基于直流负反馈原理的数字积分算法,有效克服了传统模拟积分电路和数字积分的零漂、时漂和直流偏移问题。测试结果表明,该系统在电流500 A^50 kA范围内可达到0.1级的准确度。

关键词：空心线圈铁芯线圈互感自校验大电流数字积分偏心

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