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一种基于回旋凸轮机构的沙漠植树装置

现代制造技术与装备 2024年第3期60卷 198-201页

作者：刘茗元邢家旗周文平林凯熙梁耘菘辽宁工程技术大学机械工程学院阜新123000 辽宁工程技术大学测绘与地理科学学院阜新123000

长久以来,荒漠化对人类的生存构成严重威胁。在沙漠地区使用传统的人工种植方法修复生态环境,整个作业过程费时费力,种植效率低。目前,沙漠植树机械多为半自动化且功能单一,而且受到沙漠恶劣工作环境的限制。依据上述问题,设计一种具有... 详细信息

长久以来,荒漠化对人类的生存构成严重威胁。在沙漠地区使用传统的人工种植方法修复生态环境,整个作业过程费时费力,种植效率低。目前,沙漠植树机械多为半自动化且功能单一,而且受到沙漠恶劣工作环境的限制。依据上述问题,设计一种具有自动拣苗、凸轮传送和螺旋钻孔等多功能的新型沙漠植树装置,极大地减轻了人工的劳动强度,对改善当地生态环境,推动可持续发展具有重要意义。

关键词：沙漠植树凸轮传送螺旋钻孔

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我国大气电学研究的最新进展

大气科学 2024年第1期48卷 51-75页

作者：郄秀书朱江皖底绍轩骆烁名黄子凡刘冬霞张鸿波袁善锋刘明远孙竹玲徐晨孙春发王东方蒋如斌杨静中国科学院大气物理研究所中层大气和全球环境探测重点实验室(LAGEO) 北京100029 中国科学院大学地球与行星科学学院北京100049

大气电学主要研究地球大气和近地空间发生的电学过程及其机理和影响,其核心研究内容是雷电物理和雷暴电学。自1980年代以来,中国大气电学研究不断取得新的进展,特别是近年来,得益于高时间分辨率雷电探测技术的进步,大气电学研究不仅在... 详细信息

大气电学主要研究地球大气和近地空间发生的电学过程及其机理和影响,其核心研究内容是雷电物理和雷暴电学。自1980年代以来,中国大气电学研究不断取得新的进展,特别是近年来,得益于高时间分辨率雷电探测技术的进步,大气电学研究不仅在雷电物理学和雷暴云电荷结构方面取得了重要成果,也在雷电和雷暴对近地空间的影响、强对流天气的雷电特征、以及雷电资料同化和预警预报等方面取得了重要进展。本文从六个方面对近五年来大气电学的主要研究进展进行回顾,包括高精度雷电探测和定位技术、雷电物理过程和机制、雷暴对中上层大气的影响、雷暴云电荷结构的观测和数值模拟、强对流天气的雷电特征与预报、雷电对气候变化的影响与响应等,最后对大气电学未来发展进行展望。

关键词：大气电学雷暴雷电强对流天气资料同化和预警预报

Rapidly developable therapeutic-grade equine immunoglobulin against the SARS-CoV-2 infection in rhesus macaques

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Signal Transduction and Targeted Therapy 2022年第8期7卷 2687-2689页

作者： Xiaolei liu Yi liu Xuemin Jin Zhanlong He Zhen Huang Shumin Sun Yuwei Gao Jingyu Li Qin Ning Zhongping Xie Ningyi Jin mingyuan liu State Key Laboratory for Zoonotic Diseases Key Laboratory for Zoonosis Research of the Ministry of EducationInstitute of Zoonosisand College of Veterinary MedicineJilin University130062 ChangchunChina Institute of Medical Biology Chinese Academy of Medicine Sciences&Peking Union Medical CollegeYunnan Key Laboratory of Vaccine Research and Development on Severe Infectious Diseases650118 KunmingChina Walvax Biotechnology Co. Ltd650106 KunmingChina College of Animal Science and Technology Inner Mongolia University for Nationalities028000 TongliaoChina Changchun Veterinary Research Institute Chinese Academy of Agricultural SciencesChangchunChina Yuxi JOZO Biotechnology co. LTD653199 YuxiChina National Medical Center for Major Public Health Events State Key Laboratory for Zoonotic DiseasesDepartment and Institute of Infectious DiseaseTongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina

Dear Editor,The unprecedented COVID-19 pandemic caused by SARS-CoV-2 remains ongoing,but there is a lack of fully effective *** plasma-derived hyperimmune globulins have been a safe and effective treatment but restricted by the difficulties in obtaining sufficient plasma with high antibody titers from a large number of recovered *** antibodies,particularly equine antibodies,have been widely used for decades as the therapeutics against some viral infections or as antivenoms.1 Equine antibodies could be rapidly developed and manufactured into therapeutic antibodies in large quantities under WHO standardized *** we explored the development of equine antibody-derived F(ab′)2 as an option to treat COVID-19 by targeting the receptor-binding domain(RBD)of the viral spike protein that is essential for the viral entry into the host cells.2 We observed excellent neutralization titers of the F(ab′)2 in vitro and high potency against SARS-CoV-2 infection in the nonhuman primate rhesus macaques.

关键词： quantities restricted treatment

Deep white matter hyperintensity is spatially correlated to MRI-visible perivascular spaces in cerebral small vessel disease on 7 Tesla MRI

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Stroke & Vascular Neurology 2023年第2期8卷 144-150页

作者： Yajing Huo Yilin Wang Cen Guo Qianyun liu Lili Shan mingyuan liu Haibo Wu Guanwu Li Huihui Lv Lingdan Lu Yintin Zhou Jianfeng Feng Yan Han Department of Neurology Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghaiChina Georgetown Preparatory School North BethesdaMarylandUSA Department of Radiology Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghaiChina Institute of Science and Technology for Brain-inspired Intelligence Fudan UniversityShanghaiChina

Background The association between perivascular space(PVS)and white matter hyperintensity(WMH)has been ***-appearing white matter(NAWM)around WMH is also found correlated with the development of focal *** study aims to investigate the topological connections among PVS,deep WMH(dWMH)and NAWM around WMH using 7 Tesla(7T)*** Thirty-two patients with non-confluent WMHs and 16 subjects without WMHs were recruited from our department and *** compared the PVS burden between patients with and without WMHs using a 5-point ***,the dilatation and the number of PVS within a radius of 1 cm around each dWMH were compared with those of a reference site(without WMH)in the contralateral *** this study,we define NAWM as an area within the radius of 1 cm around each ***,we assessed the spatial relationship between dWMH and *** Higher PVS scores in the centrum semiovale were found in patients with>5 dWMHs(median 3)than subjects without dWMH(median 2,p=0.014).We found there was a greater dilatation and a higher number of PVS in NAWM around dWMH than at the reference sites(p<0.001,p<0.001).In addition,79.59%of the dWMHs were spatially connected with *** dWMH,NAWM surrounding WMH and MRI-visible PVS are spatially correlated in the early stage of cerebral small vessel *** study of WMH and NAWM should not overlook MRI-visible PVS.

关键词： cerebral visible spatially

Light absorption properties and potential sources of brown carbon in Fenwei Plain during winter 2018–2019

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Journal of Environmental Sciences 2021年第4期33卷 53-63页

作者： Wenyu Zhang Weigang Wang Jie Li Shuangliang Ma Chaofan Lian Kun Li Bo Shi mingyuan liu Yanyu Li QingQing Wang Yele Sun Shengrui Tong Maofa Ge State Key Laboratory for Structural Chemistry of Unstable and Stable Species Beijing National Laboratory for Molecular Sciences(BNLMS)Chemistry Academy of Sciences Research/Education Center for Excellence in Molecular SciencesInstitute of ChemistryChinese Academy of SciencesBeijing 100190China University of Chinese Academy of Sciences Beijing 100049China State Key Laboratory of Atmospheric Boundary Layer Physics and Atmospheric Chemistry Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China Henan Environmental Monitoring Center Station Zhengzhou 450000China Laboratory of Atmospheric Chemistry Paul Scherrer Institute(PSI)Villigen 5232Switzerland Center for Excellence in Regional Atmospheric Environment Institute of Urban EnvironmentChinese Academy of SciencesXiamen 361021China Department of Clinical Research Central Hospital Affiliated to Shandong First Medical UniversityJinan 250013China

A distinctive kind of organic carbon aerosol that could absorb ultraviolet-visible radiation is called brown carbon(Br C),which has an important positive influence on radiative budget and climate *** this work,we reported the absorption properties and potential source of Br C based on a seven-wavelength aethalometer in the winter of 2018–2019 at an urban site of Sanmenxia in Fenwei Plain in central ***,the mean value of Br C absorption coefficient was 59.6±36.0 Mm^(-1) at 370 nm and contributed 37.7%to total absorption,which made a significant impact on visibility and regional *** coefficients of Br C showed double-peak pattern,and Br C had shown small fluctuations under haze days compared with clean *** for the sources of Br C,Br C absorption coefficients expressed strong correlations with element carbon aerosols and primary organic carbon aerosols,indicating that most of Br C originated from primary *** linear correlations between trace metal elements(K,As,Fe,Mn,Zn,and Pb)and Br C absorption coefficients further referred that the major sources of Br C were primary emissions,like coal burning,biomass burning,and vehicle *** moderate relationship between Br C absorption coefficients and secondary organic aerosols suggested that secondary production of Br C also played an important *** 120 hr backward air mass trajectories analysis and concentration-weighted trajectories analysis were also used to investigate potential sources of Br C in and around this area,which inferred most parts of Br C were derived from local emissions.

关键词： Brown carbon Light absorption Potential source analysis Fenwei Plain

Long-term winter observation of nitrous acid in the urban area of Beijing

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Journal of Environmental Sciences 2022年第4期34卷 334-342页

作者： Chaofan Lian Weigang Wang Yan Chen Yusheng Zhang Jingwei Zhang Yongchun liu Xiaolong Fan Chang Li Junlei Zhan Zhuohui Lin Chenjie Hua Wenyu Zhang mingyuan liu Junling Li Xuefei Wang Junling An Maofa Ge State Key Laboratory for Structural Chemistry of Unstable and Stable Species CAS Research/Education Center for Excellence in Molecular SciencesInstitute of ChemistryChinese Academy of SciencesBeijing 100190China University of the Chinese Academy of Sciences Beijing 100049China Aerosol and Haze Laboratory Advanced Innovation Center for Soft Matter Science and EngineeringBeijing University of Chemical TechnologyBeijing100029China State Key Laboratory of Atmospheric Boundary Layer Physics and Atmospheric Chemistry(LAPC) Institute of Atmospheric Physics(IAP)Chinese Academy of SciencesBeijing 100029China State Key Laboratory of Environmental Criteria and Risk Assessment Chinese Research Academy of Environmental SciencesBeijing 100012China Center for Excellence in Urban Atmospheric Environment Institute of Urban EnvironmentChinese Academy of SciencesXiamen 361021China

The particulate matter(PM)pollution has been significantly improved by carrying out various valid emission control strategies since 2013 in *** the variation trend of nitrous acid(HONO)is worthy to investigate due to its vital role in the atmospheric oxidation *** this study,field observation in the winter is conducted to investigate the concentration of HONO in an urban area of *** the winter of 2019,the mean HONO concentration is 1.38 ppbV during the whole ***-enhanced NO_(2)heterogeneous reactions on the ground and aerosol surfaces were found as the possible daytime sources of *** to O_(3),photolysis of HONO dominates the primary OH sources during the winter *** understand the HONO pollution patterns by years variation,multi-year data is summarized and finds that primary pollutants including CO and NO decreased,but secondary pollutants i.e.,HONO(mostly generated via secondary process)*** study highlights the requirement to mitigate secondary pollution by control HONO concentration.

关键词： Nitrous acid Field observation Winter air pollution

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衷中参西方法下的多发性硬化病因病机探析

上海中医药大学学报 2024年第1期38卷 67-74页

作者：张颖韩燕徐敏华丁双凤刘艳群熊明月张艳芝刘明媛上海中医药大学附属岳阳中西医结合医院上海200437 海军军医大学长海医院上海200433 上海市奉贤区中心医院上海201400

多发性硬化是一种中枢神经系统自身免疫性脱髓鞘疾病,该病的研究多见于西医。近年来中医对多发性硬化的认识逐渐深入,中医学者多从湿热、伏毒、督肾阳虚等方面解释本病病机。古籍中对该病的症状和病因病机描述颇多,然则较为分散,缺乏系... 详细信息

多发性硬化是一种中枢神经系统自身免疫性脱髓鞘疾病,该病的研究多见于西医。近年来中医对多发性硬化的认识逐渐深入,中医学者多从湿热、伏毒、督肾阳虚等方面解释本病病机。古籍中对该病的症状和病因病机描述颇多,然则较为分散,缺乏系统梳理。通过分析和整理多发性硬化相关的中医古籍为基础,同时参考西医现代化研究的理论,总结该病发病过程为正气亏虚、肺热叶焦、遗毒内伏、久热伤阴;发病基础在于肺肾不和、残余之邪未净,内外合邪则病复不全。系统归纳和阐述其病因病机,可丰富多发性硬化的中医理论内涵,为多发性硬化的现代临床诊疗提供新思路。

关键词：多发性硬化病因病机中医西医

A strategy for enhancing luminescence thermometry via Ta^(5+)-triggered K_(0.5)Na_(0.5)NbO_(3):Er^(3+)transparent ceramics

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Journal of Materiomics 2024年第5期10卷 984-994页

作者： Quan Zhang Zetian Yang mingyuan Wang Yang liu Shuangying Lei Laihui Luo Dirk Poelman Key Laboratory of MEMS of Ministry of Education School of Electrical Science and EngineeringSoutheast UniversityNanjing210096China LumiLab Department of Solid StateSciencesGhent UniversityKrijgslaan 281-S1GhentB-9000Belgium School of Materials Science and Engineering Nanjing University of Science and TechnologyNanjing210094China Department of Microelectronic Science and Engineering Ningbo UniversityNingbo315211China

Luminescence thermometry is a reliable approach for remote thermal sensing,and extensive studies have been devoted to designing a luminescence thermometer with heightened thermal ***,we report a promising luminescence thermometric material,Ta^(5+)-substituted K_(0.5)Na_(0.5)NbO_(3):0.003Er^(3+)transparent ferroelectric *** temperature sensing sensitivity is significantly improved by adjusting the concentration of Ta^(5+)in the ***,utilizing the fluorescence intensity ratio from the 2H_(11/2) and 4S_(3/2) thermally coupled states of Er^(3+)as a detecting signal within the temperature range of 273–543 K,an optimal maximum absolute sensitivity of 0.0058 K–1 and relative sensitivity of 0.0158 K–1 are achieved for K_(0.5)Na_(0.5)NbO_(3):0.65Ta^(5+)/0.003Er^(3+).Simultaneously,as the concentration of Ta5+increase,a unique evolution of structural phase transitions is observed from orthorhombic to tetragonal and then to *** is accompanied by an improvement in luminescence temperature sensing properties,and the best sensitivity is demonstrated in the cubic-phase ***,a huge change in infrared luminescence properties as a function of temperature is found around the structure transition temperature of the *** results indicate a promising potential for achieving highly sensitive thermometry or monitoring phase structure transitions through luminescence thermometry behavior in the K_(0.5)Na_(0.5)NbO_(3) host.

关键词： Transparent ceramics Temperature sensing Phase transition Upconversion emission

基于自主学习理念的多元化医学教学方法设计与实践

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继续医学教育 2024年第6期38卷 67-70页

作者：杨玉苗秋实王静艳张鹏霞刘明远商宇佳木斯大学基础医学院黑龙江佳木斯154000 佳木斯大学附属第一医院消化内科黑龙江佳木斯154000 佳木斯大学附属第一医院康复医学科黑龙江佳木斯154000

自主学习是教育研究的重要课题,学生自主学习的实现要求教师发挥其导向作用,引领与培养学生自主学习的意识与能力。基于此背景,本研究设计了适用于医学课程的基于自主学习理念的多元化教学法。本教学法以自主学习模型为基本架构,并结合... 详细信息

自主学习是教育研究的重要课题,学生自主学习的实现要求教师发挥其导向作用,引领与培养学生自主学习的意识与能力。基于此背景,本研究设计了适用于医学课程的基于自主学习理念的多元化教学法。本教学法以自主学习模型为基本架构,并结合第二课堂等教学方法,更加突出了教师在教学过程中的引导作用。在教学实践中,教师团队将《药理学》作为教学改革的实验课程,针对的对象是本校的临床医学专业本科生。本次教学改革分为3个阶段进行。在教学准备阶段,教师引导学生明确目标,并提升他们的自我效能感。在教学实施阶段,教师引导学生选择和使用合适的学习策略。在教学反思阶段,教师引导学生进行自我评价。教学活动主要以师生座谈会和教学沙龙的形式开展,内容主要包括教授学习策略、激发学生的自我效能感、促进学生主动学习和自我管理。研究发现,该教学模式不仅能够有效改善学生的整体成绩分布,而且大部分学生在此模式下表现出良好的学习自主性。因此,相较于传统的讲授式教学法,多元化教学法在培养学生自主学习能力方面具有明显的优势,对医学人才的培养产生了积极影响。

关键词：多元化教学法自主学习第二课堂医学课程药理学教学改革