检索结果-南通市图书馆

Emergence of a novel multi-resistance-mediating integrative and conjugative element ICEPmu3 in Pasteurella multocida

引用

Journal of Integrative Agriculture 2024年第11期23卷 3938-3942页

作者： Jiao He Zhishuang Yang mingshu wang Renyong Jia Shun Chen Mafeng Liu Xinxin Zhao Qiao Yang Ying Wu Shaqiu Zhang Juan Huang Xumin Ou Di Sun Bin Tian Yu He Zhen Wu Anchun Cheng Dekang Zhu Research Center of Avian Diseases College of Veterinary MedicineSichuan Agricultural University International Joint Research Center for Animal Disease Prevention and Control of Sichuan Province Engineering Research Center of Southwest Animal Disease Prevention and Control Technology Ministry of Education Key Laboratory of Agricultural Bioinformatics Ministry of Education

Pasteurella multocida (PM) has been infecting a variety of hosts for a long time,causing sustained economic losses worldwide;however,there have been limited studies on its extensive adaptability (Aktories et al.2012).Analysis of strains data collected in our laboratory revealed that PM typically acquires foreign genes through transformation and conjugation,rather than transformation and *** and conjugative elements (ICEs)are a crucial mechanism that leads to abrupt changes in niche preferences and enhances environmental adaptability for bacteria,with their number far exceeding the number of plasmids and phages (Wozniak and Waldor 2010;Johnson and Grossman 2015;Botelho and Schulenburg 2021).Previous research has shown that the European bovine-sourced strain Pm36950 contains the experimentally transferable resistant ICEPmu1,which could integrate into the host chromosome or forming a circular intermediate (Michael et al.2012).Additionally,a few studies have suggested that PM strains isolated from European bovine and Asian swine might contain ICEs,but these claims lack experimental verification (Klima et al.2014;Moustafa et al.2015;Kadlec et al.2017;Peng et al.2017;Beker et al.2018;Schink et al.2022).Currently,there is no data available on ICE-carrying PM strains isolated from hosts outside of European cattle or Chinses *** letter presents a report on a novel ICE identified in the hypervirulent and multidrug-resistant PM HN141014 strain isolated from Chinese *** ICE was specifically analyzed for its resistance genes,transferable capacity and host diversity.

关键词：

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

印度英语词汇变异的认知社会语言学探究

引用

绵阳师范学院学报 2024年第3期43卷 55-61页

作者：王钤王明树四川外国语大学英语学院重庆400031 四川外国语大学翻译学院重庆400031

认知社会语言学把认知模型对意义的研究和基于用法的语言模型研究相结合,为语言变体研究提供了新的视角与方法。同一语言由于交际情境的差异以及使用群体的差异,不仅会表现出不同的语言形态,而且会出现语言变异。在认知社会语言学视角下... 详细信息

认知社会语言学把认知模型对意义的研究和基于用法的语言模型研究相结合,为语言变体研究提供了新的视角与方法。同一语言由于交际情境的差异以及使用群体的差异,不仅会表现出不同的语言形态,而且会出现语言变异。在认知社会语言学视角下,以印度英语为例,分析了诸多社会和认知因素对词汇变异的影响。研究显示,词汇会因认知体验和社会环境等多种因素产生变异。从认知社会语言学视角对词汇变异进行研究,有助于更加明确地解释词汇变异的过程和根源。

关键词：词汇变异认知社会语言学印度英语

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Modeling projected changes of mangrove biomass in different climatic scenarios in the Sunda Banda Seascapes

引用

International Journal of Digital Earth 2017年第4期10卷 457-468页

作者： mingshu wang Marguerite Madden Ian Hendy Estradivari Gabby N.Ahmadia Department of Geography University of GeorgiaAthensGAUSA The Institute of Marine Sciences University of PortsmouthPortsmouthUK Yayasan World Wildlife Fund-Indonesia JakartaIndonesia Oceans Conservation World Wildlife Fund-USWashingtonDCUSA

Mangroves are critical in the ecological,economic and social development of coastal rural and urban ***,they are under threat by climate change and anthropogenic *** Sunda Banda Seascape(SBS),Indonesia,is among the world’s richest regions of mangrove biomass and *** inform current and future management strategies,it is critical to provide estimates of how mangroves will respond to climate change in this ***,this paper utilized spatial analysis with model-based climatic indicators(temperature and precipitation)and mangrove distribution maps to estimate a benchmark for the mangrove biomass of the SBS in six scenarios,namely the Last Inter-glacial Period,the current scenario(1950-2000)and all four projected Representative Concentration Pathways in 2070 due to climate *** mangroves gaining more biomass with climate change(the increase in CO_(2)concentration),this paper highlighted the great proportion of below-ground biomass in mangrove *** also showed that the changes in spatial distribution of mangrove biomass became more variable in the context of climate *** mangroves have been proposed as an essential component of climate change strategies,this study can serve as a baseline for future studies and resource management strategies.

关键词： Mangrove forests biomass climate change IPCC GIS natural resources

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Reproductive toxicity study with a novel deoxyguanosine analogue （Metacavir） in pregnant SD rats

引用

Frontiers of Medicine 2015年第1期9卷 82-89页

作者： Qihui Luo Zhengli Chen Anchun Cheng mingshu wang Jing Fang Xi Peng Li Tang Key Laboratory of Animal Disease and Human Health of Sichuan Province Ya 'an 625014 China Institute of Preventive Veterinary Medicine Sichuan Agricultural University Chengdu 611130 China

Our preliminary studies demonstrated that Metacavir has potential to become a new anti-HBV agent. The main targets of the toxic effects of Metacavir, in rhesus monkeys, were gastrointestinal tracts, liver, blood, and kidneys, which were not related to mitochondrial effects. In this study, the maternal toxicity, embryo-fetal developmental toxicity and teratogenicity were studied in pregnant Sprague-Dawley rats after intragastric administration of Metacavir （200, 100, 50, 0 mg/kg body weight） during the first 6-15 days of pregnancy. Slower weight gain was observed in 5 out of 21 rats subjected to a 200 mg/kg dose, as well as 2 out of 20 subjected to a 100 mg/kg dose. Compared with the solvent control group, the calibration weight gain in the 200 mg/kg and 100 mg/kg dosage groups respectively, during first 6-20 pregnant days were significantly different （P 〈 0.01, P 〈 0.05）. Significant dose related adverse effects to other reproductive parameters were not seen in F0 and F1, but the number of stillbirths in high dose group showed notably difference compared with the control group （P 〈 0.05）, while the litter incidence showed no difference. No Metacavir-associated pathological changes were observed. The present research indicated that at a dose of 200 mg/（kg·d）（i.e., 40 times the effective dose in rats）, Metacavir shows some maternal toxicity to SD rats. The embryotoxicity in the 200 mg/kg group encompass decreased fetal body weight, and higher fetal mortality rates, compared with the control group. However, the litter incidence showed no statistical difference. All the treated rats displayed normal bone development, no teratogenicity and without adverse effects on fetal development, thus indicating that below a dose of 200 mg/（kg· d） there is no teratogenic side effects.

关键词： deoxyguanosine analogue Metacavir pregnancy maternal toxicity embryo toxicity teratogenicity

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

A Model for Detecting Fake News by Integrating Domain-Specific Emotional and Semantic Features

引用

Computers, Materials & Continua 2024年第8期80卷 2161-2179页

作者： Wen Jiang mingshu Zhang Xu’an wang Wei Bin Xiong Zhang Kelan Ren Facheng Yan College of Cryptography Engineering Engineering University of People’s Armed PoliceXi’an710086China Key Laboratory of Network and Information Security Engineering University of People’s Armed PoliceXi’an710086China Key Laboratory of CTC&Information Engineering Engineering University of People’s Armed PoliceMinistry of EducationXi’an710086China

With the rapid spread of Internet information and the spread of fake news,the detection of fake news becomes more and more *** detection methods often rely on a single emotional or semantic feature to identify fake news,but these methods have limitations when dealing with news in specific *** order to solve the problem of weak feature correlation between data from different domains,a model for detecting fake news by integrating domain-specific emotional and semantic features is *** method makes full use of the attention mechanism,grasps the correlation between different features,and effectively improves the effect of feature *** algorithm first extracts the semantic features of news text through the Bi-LSTM(Bidirectional Long Short-Term Memory)layer to capture the contextual relevance of news ***-BiLSTM is then used to extract emotional features and predict the probability of positive and negative emotions in the *** then uses domain features as an enhancement feature and attention mechanism to fully capture more fine-grained emotional features associated with that ***,the fusion features are taken as the input of the fake news detection classifier,combined with the multi-task representation of information,and the MLP and Softmax functions are used for *** experimental results show that on the Chinese dataset Weibo21,the F1 value of this model is 0.958,4.9% higher than that of the sub-optimal model;on the English dataset FakeNewsNet,the F1 value of the detection result of this model is 0.845,1.8% higher than that of the sub-optimal model,which is advanced and feasible.

关键词： Fake news detection domain-related emotional features semantic features feature fusion

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

利用云模型评价开发区的土地集约利用状况

引用

农业工程学报 2012年第10期28卷 247-252页

作者：王明舒朱明南京大学地理与海洋科学学院南京210093

针对当前开发区土地集约评价中权重确定方法受主观性影响较大的问题,该文提出基于云模型的权重确定方法。将云模型引入开发区土地集约利用评价,并以桂林国家级高新技术产业开发区为例,进行实证研究。研究结果表明桂林高新区土地利用集... 详细信息

针对当前开发区土地集约评价中权重确定方法受主观性影响较大的问题,该文提出基于云模型的权重确定方法。将云模型引入开发区土地集约利用评价,并以桂林国家级高新技术产业开发区为例,进行实证研究。研究结果表明桂林高新区土地利用集约度综合分值为0.889,用地供需基本平衡;从土地利用状况而言,其土地利用强度较高、工业用地水平较强;就用地效益而言,工业用地产出强度较好,高新技术产业用地产出强度较高;从管理绩效来看,截止评价时点,区内无闲置土地,监管成效显著。基于云模型确定权重值的方法具备结果更加客观,算法容易实现的优点,有助于促进土地集约利用的科学评价,为桂林高新区土地集约利用政策依据。

关键词：土地利用模型指标土地集约利用云模型开发区桂林

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

苗药艾纳香挥发油提取工艺优化及不同产地的品质评价

引用

中国民族民间医药 2024年第14期33卷 14-21页

作者：汪明蜀王可可张文龙龙友邻杜富强毛春茂李洪凤吴向莉贵州中医药大学药学院贵州贵阳550025 贵州丰泰农业开发有限公司贵州册亨552204 贵州威门药业股份有限公司贵州贵阳550014

目的:优化艾纳香挥发油提取工艺并对5个不同产地10个采集点的栽培及野生艾纳香挥发油主要品质指标进行初步评价。方法:采用超声辅助水蒸气蒸馏法,通过正交实验提取艾纳香挥发油,以提取温度、提取时间、药材粉碎度、浸泡时间、料液比、... 详细信息

目的:优化艾纳香挥发油提取工艺并对5个不同产地10个采集点的栽培及野生艾纳香挥发油主要品质指标进行初步评价。方法:采用超声辅助水蒸气蒸馏法,通过正交实验提取艾纳香挥发油,以提取温度、提取时间、药材粉碎度、浸泡时间、料液比、超声时间为考察指标,挥发油提取率为评价指标;采用气相色谱法(GC)对艾纳香挥发油进行含量测定及成分分析。结果:挥发油最佳提取温度为115℃、提取时间为3 h、药材粉碎度为3号筛(50目)、浸泡时间为1 h、料液比为1∶16(g∶mL)、超声为20 min;野生和栽培艾纳香在挥发油含量上无显著差异,栽培药材提取的艾纳香挥发油中L-龙脑、β-蒎烯、芳樟醇、β-石竹烯的含量均高于野生艾纳香挥发油中的含量。结论:所建立的挥发油提取工艺稳定可行,人工种植艾纳香挥发油质量优于野生艾纳香挥发油。

关键词：艾纳香水蒸气蒸馏法超声辅助正交试验品质

来源：

维普期刊数据库博看期刊

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

苗药艾纳香艾片提取工艺优化及不同产地的品质评价

引用

山东化工 2024年第9期53卷 76-80页

作者：毛春茂王可可张文龙龙友邻丁宁汪明蜀杜富强李洪凤卢泽婷贵州中医药大学药学院贵州贵阳550025 贵州丰泰农业开发有限公司贵州册亨552204 贵州威门药业股份有限公司贵州贵阳550014

目的:优化艾片提取工艺并对5个不同产地10个采集点的栽培及野生艾片主要品质指标进行初步评价。方法:采用超声辅助水蒸气蒸馏法,通过正交实验设计提取艾片,以料液比、超声时间、浸泡时间、提取时间为考察指标,艾片提取率为评价指标,采... 详细信息

目的:优化艾片提取工艺并对5个不同产地10个采集点的栽培及野生艾片主要品质指标进行初步评价。方法:采用超声辅助水蒸气蒸馏法,通过正交实验设计提取艾片,以料液比、超声时间、浸泡时间、提取时间为考察指标,艾片提取率为评价指标,采用气相色谱法(GC)对艾片进行含量测定及成分分析。结果:艾片最佳提取条件为料液比1∶12(g∶mL)、超声25 min、浸泡时间75 min、提取时间90 min;野生和栽培艾纳香在艾片提取率上均存在显著差异。结论:本实验建立的艾片提取工艺稳定可行,人工种植艾片质量优于野生艾片。

关键词：艾纳香艾片品质水蒸气蒸馏法提取

来源：

维普期刊数据库

同方期刊数据库博看期刊评论

在线全文

学校读者我要写书评

暂无评论

MXene Sediment-Based Poly(vinyl alcohol)/Sodium Alginate Aerogel Evaporator with Vertically Aligned Channels for Highly Efficient Solar Steam Generation

引用

Nano-Micro Letters 2024年第10期16卷 638-654页

作者： Tian wang Meng Li Hongxing Xu Xiao wang mingshu Jia Xianguang Hou Shuai Gao Qingman Liu Qihang Yang Mingwei Tian Lijun Qu Zhenhua Song Xiaohu Wu Lili wang Xiansheng Zhang Shandong Key Laboratory of Medical and Health Textile Materials College of Textiles and ClothingState Key Laboratory of Bio-Fibers and Eco-TextilesResearch Center for Intelligent and Wearable TechnologyQingdao UniversityQingdao 266071People's Republic of China Department of Pharmacology Qingdao University School of PharmacyQingdao UniversityQingdao 266071People's Republic of China Shandong Institute of Advanced Technology Jinan 250100People's Republic of China College of Electromechanical Engineering Qingdao University of Science and TechnologyQingdao 266061People's Republic of China

Solar-driven interfacial evaporation from seawater is considered an effective way to alleviate the emerging freshwater crisis because of its green and environmentally friendly ***,developing an evaporator with high efficiency,stability,and salt resistance remains a key ***,with an internal photothermal conversion efficiency of 100%,has received tremendous research interest as a photothermal ***,the process to prepare the MXene with monolayer is inefficient and generates a large amount of“waste”MXene sediments(MS).Here,MXene sediments is selected as the photothermal material,and a three-dimensional MXene sediments/poly(vinyl alcohol)/sodium alginate aerogel evaporator with vertically aligned pores by directional freezing method is innovatively *** vertical porous structure enables the evaporator to improve water transport,light capture,and high evaporation *** swabs and polypropylene are used as the water channel and support,respectively,thus fabricating a self-floating *** evaporator exhibits an evaporation rate of 3.6 kg m^(-2)h^(-1)under one-sun illumination,and 18.37 kg m^(-2)of freshwater is collected in the condensation collection device after 7 h of outdoor sun *** evaporator also displays excellent oil and salt *** research fully utilizes“waste”MS,enabling a self-floating evaporation device for freshwater collection.

关键词： MXene sediments Porous structure Desalination Self-floating

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Construction of an Infectious Clone for Mosquito-Derived Tembusu Virus Prototypical Strain

引用

Virologica Sinica 2021年第6期36卷 1678-1681页

作者： Xiaoli wang Yu He Jiaqi Guo Bowen Jiang mingshu wang Renyong Jia Dekang Zhu Mafeng Liu Xinxin Zhao Qiao Yang Ying Wu Shaqiu Zhang Yunya Liu Ling Zhang Yanling Yu Anchun Cheng Shun Chen Research Center of Avian Disease College of Veterinary MedicineSichuan Agricultural UniversityChengdu 611130China Institute of Preventive Veterinary Medicine College of Veterinary MedicineSichuan Agricultural UniversityChengdu 611130China Key Laboratory of Animal Disease and Human Health of Sichuan Province Chengdu 611130China

Dear Editor,Duck Tembusu virus(DTMUV),a member of the Flavivirus genus within the Flaviviridae family,has caused huge economic losses to the poultry industry in China and even in Asia since 2010(Zhang et al.2017).The first strain of Tembusu virus(TMUV)MM_1775 was isolated from mosquitoes in 1955 in Malaysia(Platt et al.1975).DTMUV CQW1 strain(GenBank:KM233707.1)was isolated from the liver tissue of Cherry Valley ducks in southwest China in 2015(Zhu et al.2015).The positive control rCQW1 was rescued from an infectious clone that contained the full-length cDNA of *** the complete cDNA was positioned under the control of the T7 promoter elements for in vitro transcription(Chen et al.2018).The relationship between TMUV evolution and pathogenic variants has not been *** fundamental reason is the lack of the in vitro operation platform for the prototypical strain genome.

关键词： poultry Infectious Clone

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：