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Thornthwaite moisture index and depth of suction change under current and future climate‒An Australian study

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第5期16卷 1761-1775页

作者： md Rajibul Karim Bikash Devkota md Mizanur Rahman Hoang Bao Khoi Nguyen UniSA STEM University of South AustraliaMawson Lakes CampusMawson LakesSouth Australia5095Australia

Climate change is one of the major global challenges and it can have a significant influence on the behaviour and resilience of geotechnical *** changes in moisture content in soil lead to effective stress changes and can be accompanied by significant volume changes in reactive/expansive *** volume change leads to ground movement and can exert additional stresses on structures founded on or within a shallow depth of such *** change is likely to amplify the ground movement potential and the associated problems are likely to *** effect of atmospheric boundary interaction on soil behaviour has often been correlated to Thornthwaite moisture index(TMI).In this study,the long-term weather data and anticipated future projections for various emission scenarios were used to generate a series of TMI maps for *** changes in TMI were then correlated to the depth of suction change(H s),an important input in ground movement *** all climate scenarios considered,reductions in TMI and increases in H s values were observed.A hypothetical design scenario of a footing on expansive soil under current and future climate is *** is observed that a design that might be considered adequate under the current climate scenario,may fail under future scenarios and accommodations should be made in the design for such events.

关键词： Climate change Future prediction Thornthwaite moisture index(TMI) Characteristic surface movement Infrastructure resilience

ALTERATION IN ENTEROCYTE GENE EXPRESSION MAY EXPLAIN STRUCTURAL AND FUNCTIONAL CHANGES FOLLOWING GLUTAMINE SUPPLEMENTED PARENTERAL NUTRITION

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Chinese Medical Sciences Journal 1999年第2期14卷 112-116页

作者： JiangZhuming,md LiuYuewu,md,phd MaYongxian,md BaiManxi,md,phd QiangBoqing,phd RobertSmith,md DepartmentofSurgery PekingUnionMedicalCollegeHospitalBeijing100730 MolecularBiologyLaboratoryofChineseAcademyofMedicalSciences Beijing100730 JoslinDiabeticCenter DepartmentofSurgeryMassachusettsGeneralHospitalandBrighamandWomen＇sHospitalHarvardMedicalSchool

Following extensive bowel resection, the intestinal tract undergoes a variety of adaptive responses to enhance bowel function. The purpose of this study was to determine the effect of glutamine-supplemented parenteral nutrition on mucosal cellularity and gut function. In addition, enterocyte gene expression of two relevant systems was also characterized and related to the structural and functional changes that occurred. Male Wistar rats underwent a 60% small bowel resection and jugular vein catheterization and were randomized into two groups. The control group (n = 10) received a standard intravenous nutritional solution and the study group (n = 10) received a similar solution but enriched with alanylglutamine dipeptide. After 7 days blood was taken for amino acid analysis, and bowel was harvested to determine mucosal morphology and expression of mucosal cell glutaminase and IGF-I mRNA. Mesentery lymphnodes were cultured to determine the presence of bacteria and thus access bacteria translocation. Serum glutamine concentration and mucosal architecture were maintained in the study group compared to the controls. Seventy percent of lymphnodes were cultured positive in control vs. only 20% in the study group (P

关键词： Parenteral Nutrition Animals Dipeptides Enterocytes Gene Expression Glutaminase Ileum Insulin-Like Growth Factor I Intestinal Mucosa Intestine, Small Jejunum Male RNA, Messenger Rats Rats, Wistar Research Support, Non-U.S. Gov't

ALTERATION IN ENTEROCYTE GENE EXPRESSION MAY EXPLAIN STRUCTURAL AND FUNCTIONAL CHANGES FOLLOWING GLUTAMINE SUPPLEMENTED PARENTERAL NUTRITION

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Chinese Medical Sciences Journal 1999年第2期 49-53页

作者： $$$$ Jiang Zhuming, md Liu Yuewu, md, phd , Ma Yongxian, md , Bai Manxi,md, phd , Qiang Boqing, phd  ,Robert Smith, md Wlley Souba, md , ScD and Douglas Wilmore, md Department of Surgery, Peking Department of Surgery Peking Union Medical College Hospital Beijing 100730 Molecular Biology Laboratory of Chinese Academy of Medical Sciences Beijing 100730 Joslin Diabetic Center Department of Surgery Massachusetts General Hospital and Brigham and Women's Hospital Harvard Medical School

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Inherited Wolff–Parkinson–White Syndrome

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Cardiovascular Innovations and Applications 2016年第B2期1卷 187-197页

作者： Yang Liu,md,phd Yumei Xue,md,phd Shulin Wu,md,FACC,FHRS Dan Hu,md,phd,FHRS Guangdong Cardiovascular Institute Guangdong General HospitalGuangdong Academy of Medical SciencesGuangzhou 510080China Department of Molecular Genetics and Experimental Cardiology Masonic Medical Research LaboratoryUticaNY 13501USA

Wolff-Parkinson-White(WPW)syndrome is a congenital disorder of cardiac conduction system characterized by electrocardiographic preexcitation and episodes of paroxysmal supraventricular *** is caused by a cardiac developmental defect in the electrical insulation between the atria and the ventricles due to the presence of an accessory *** syndrome is a common cause of supraventricular tachycardia with benign ***,this clinical entity also predisposes patients to an increased risk of sudden cardiac death,especially in the setting of preexcited atrial *** syndrome is usually sporadic and of unknown etiology in most *** the past10years,a signifi cant heritable factor is increasingly *** cation of the genetic basis among patients with WPW syndrome has important implications for understanding the molecular mechanism of ventricular preexcitation and the development of therapeutic strategies for risk stratifi cation and *** goal of this review is to examine the previous studies on hereditary variants,as well as to outline potential future avenues toward defi ning the heritability of WPW syndrome.

关键词： Wolff-Parkinson-White syndrome ventricular preexcitation genetics

Moving into a new era—SCIE coverage is the next rung on the ladder for Genes&Diseases

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Genes & Diseases 2019年第4期6卷 327-327页

作者： T.-C.he md. phd The University of Chicago Medical Center Molecular Oncology Laboratory/Dept of Orthopaedic Surgery5841 South Maryland Avenue.MC 3079ChicagoIL60637United States

In a letter dated August 30,2019 from Marian Hollingsworth,Director of Publisher Relations for the Web of Science Group Clarivate Analytics,Philadelphia,PA,USA,we were informed that Genes&Diseases has been selected for Science Citation Index Expanded(SCIE)coverage in the Genetics&heredity and Biochemistry&Molecular Biology categories of the Clarivate Analytics products and *** with Volume 4(1),2017,Genes&Diseases will be indexed and abstracted in Science Citation Index Expanded(SCIE,also known as SciSearch),Journal Citation Reports/Science Edition,Current Contents/Life Sciences,and Biological *** first release of the journal’s Impact Factor(IF)is anticipated in June 2020.

关键词： Genes&Diseases Impact Factor Molecular Medicine Personalized Medicine SCI Translational Medicine

“Eye Science” in 2011

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Eye Science 2011年第1期26卷 1-2页

作者： Jian Ge md phd Zhongshan Ophthalmic Center Guangzhou

2011 is an opportune time for Yanke Xuebao (Eye Science) to launch its bilingual edition as a platform for cooperation between Chinese and international vision *** yearly research output of Chinese investigators in all fields of science, but particularly biomedicine, has been growing recently by leaps and *** an example, the American Journal of Ophthalmology (AJO), one of the most prestigious clinical journals in our field,received more submissions from East Asian authors (Japan, China and Korea alone)than they did from the United States in *** investigators ranked third on the list, climbing rapidly, only after the US and *** vision research centers in China, such as Zhongshan Ophthalmic Center, where Eye Science is published, now rank alongside Moorfields and Johns Hopkins as among the most prolific institutions in the world, measured by articles appearing annually in peer-reviewed SCI journals.

关键词：《眼科学报:英文版》期刊编辑部 2011年

Antiplatelet Therapy Considerations in Women

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Cardiovascular Innovations and Applications 2019年第B2期3卷 363-373页

作者： Khadeeja Esmail,md Dominick J.Angiolillo,md,phd University of Florida College of MedicineJacksonvilleFLUSA

Coronary artery disease(CAD)is the leading cause of death worldwide,but because of several factors,one of which is antiplatelet therapy,the mortality rates have steadily ***,women continue to experience higher CAD mortality rates than *** may be explained by differences in comorbidities,increased time to presentation,higher bleeding rates,and differences in *** are numerous landmark trials in the field of antiplatelet therapy;however,women are consistently underrepresented in these *** results of these trials reveal that women experience the same benefit as men from antiplatelet therapy but experience higher bleeding rates;therefore bleeding-reduction strategies are imperative in this patient *** review provides an overview of the available evidence on CAD in women and its implications for antiplatelet medications.

关键词： antiplatelet therapy women atherosclerosis

Effects of Location and Extension of Portal Vein Tumor Thrombus on Long-Term Outcomes of Surgical Treatment for hepatocellular Carcinoma

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Effects of Location and Extension of Portal Vein Tumor Throm...

Inhibitions of Synuclein-gamma Expression and Fnnction Increase the Sensitivity of Breast Cancer cells to Paclitaxel Treatment

山东抗癌协会普外肿瘤专业委员会第三次学术会议

作者： Xiao-Ping Chen, md, phd, FACS, Fa-Zu Qiu, md, phd, Zai-De Wu, md, phd, Zhi-Wei Zhang, md, phd, Zhi-Yong Huang, md, phd, Yi-Fa Chen, md, phd, Bi-Xiang Zhang, md, phd, Song-Qing he, md, phd, and Wan-Guang Zhang, md, phd hepatic Surgery Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430030 Wuhan. People''s Republic of China

＜正＞Background: The role of surgical resection and thrombectomy for hepatocellular carcinoma （HCC） with portal vein tumor thrombus （PVTT） is controversial. This study aimed to evaluate the effects of the location and extent of PVTT on the long-term outcomes of surgical treatment for HCC. Methods: A total of 438 patients with HCC and PVTT underwent liver resection with or without thrombectomy. These 438 patients were divided into 2 groups: in group A, PVTT was located in the hepatic resection area or protruded into the first branch of the main portal vein beyond the resection line for ＜ 1 cm （286 patients）, and in group B, PVTT extended into the main portal vein （1S2 patients）. Concomitant thrombectomy was performed in 147 patients （51.4%） of group A and in all patients of group B. Results: PVTT recurrence within 6 months after surgery in group B was significantly higher than that in group A: 76.9% vs. 11.3%. Remnant liver recurrence within 1 year after surgery was 43.0% in group A and 78.8% in group B. The cumulative 1-, 2-. 3-, and 5-year overall survival rates were 58.7%, 39.9%, 22.7%, and 18.1% for group A and 39.5%. 20.4%, 5.7%, and 0% for group B, respectively. The overall survivals were significantly better in group A than group B （P ＜ .02）. Conclusions: Liver resection with thrombectomy yielded better outcomes in the HCC patients with PVTT confined to the first or second branch of the main portal vein compared with PVTT extending into the main portal vein.

关键词： hepatocellular carcinoma-Portal vein tumor thrombus-Liver resection-Survival-Thrombectomy.

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Inhibitions of Synuclein-gamma Expression and Fnnction Incre...