检索结果-南通市图书馆

Multimodal abnormalities of brain structures in adolescents and young adults with major depressive disorder:An activation likelihood estimation meta-analysis

引用

World Journal of Psychiatry 2024年第7期14卷 1106-1117页

作者： Yan-Ping Shu Qin Zhang Yong-zhe hou Shuang Liang Zu-Li zheng Jia-Lin Li Gang Wu Department of Psychiatry of Women and Children The Second People’s Hospital of Guizhou ProvinceGuiyang 550000Guizhou ProvinceChina Department of Radiology The Second People’s Hospital of Guizhou ProvinceGuiyang 550000Guizhou ProvinceChina Department of Radiology Guizhou Provincial People’s HospitalGuiyang 550000Guizhou ProvinceChina Medical Humanities College Guizhou Medical UniversityGuiyang 550000Guizhou ProvinceChina

BACKGROUND Major depressive disorder(MDD)in adolescents and young adults contributes significantly to global morbidity,with inconsistent findings on brain structural changes from structural magnetic resonance imaging *** likeli-hood estimation(ALE)offers a method to synthesize these diverse findings and identify consistent brain *** We performed a comprehensive literature search in PubMed,Web of Science,Embase,and Chinese National Knowledge Infrastructure databases for neuroi-maging studies on MDD among adolescents and young adults published up to November 19,*** independent researchers performed the study selection,quality assessment,and data *** ALE technique was employed to synthesize findings on localized brain function anomalies in MDD patients,which was supplemented by sensitivity *** Twenty-two studies comprising fourteen diffusion tensor imaging(DTI)studies and eight voxel-based morphome-try(VBM)studies,and involving 451 MDD patients and 465 healthy controls(HCs)for DTI and 664 MDD patients and 946 HCs for VBM,were ***-based ALE demonstrated significant reductions in fractional anisotropy(FA)values in the right caudate head,right insula,and right lentiform nucleus putamen in adolescents and young adults with MDD compared to HCs,with no regions exhibiting increased FA ***-based ALE did not demonstrate significant alterations in gray matter *** analyses highlighted consistent findings in the right caudate head(11 of 14 analyses),right insula(10 of 14 analyses),and right lentiform nucleus putamen(11 of 14 analyses).CONCLUSION Structural alterations in the right caudate head,right insula,and right lentiform nucleus putamen in young MDD patients may contribute to its recurrent nature,offering insights for targeted therapies.

关键词： Major depressive disorder Adolescent Young adults Neuroimaging Diffusion tensor imaging Voxel-based morphometry Activation likelihood estimation Meta-analysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Pressure-induced color change arising from transformation between intra-and inter-band transitions in LuH_(2±x)N_(y)

引用

Science China(Physics,Mechanics & Astronomy) 2024年第2期67卷 161-166页

作者： zhe Liu Yingjie Zhang Shenyang Huang Xue ming Qing Li Chenghao Pan Yaomin Dai Xiaoxiang Zhou Xiyu Zhu Hugen Yan Hai-Hu Wen Center for Superconducting Physics and Materials National Laboratory of Solid State Microstructures and Department of PhysicsNational Collaborative Innovation Center of Advanced MicrostructuresNanjing UniversityNanjing 210093China State Key Laboratory of Surface Physics Key Laboratory of Micro and Nano-Photonic Structures of the Ministry of EducationDepartment of PhysicsFudan UniversityShanghai 200433China

The pressure-induced color change in the nitrogen-doped lutetium hydride has triggered extensive discussions about the underlying physics and potential ***,we study the optical response of LuH_(2±x)N_(y)in a broad frequency range at ambient pressure and its evolution with pressure in the visible spectral *** broad-band optical spectra at ambient pressure reveal a Drude component associated with intra-band electronic transitions and two Lorentz components(L1 and L2)arising from inter-band electronic *** application of pressure causes a spectral weight transfer from L1 to the Drude component,leading to a blue shift of the plasma edge in the reflectivity spectrum alongside a reduction of the high-frequency *** results suggest that the pressure-induced color change in LuH_(2±x)N_(y)is closely related to the transformation between intra-and inter-band electronic transitions,providing new insights into the mechanism of the pressure-induced color change in LuH_(2±x)N_(y).

关键词： nitrogen-doped lutetium hydride optical spectroscopy high-pressure technique color change

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Nanoindentation behavior and creep-induced cracking of long-term crept austenitic steel at 650℃

引用

Journal of Iron and Steel Research International 2024年第2期31卷 464-474页

作者： zhen Zhang Yu-hang Duan Shuai Wang Jin-shan Chen An-zhe Wang Xiang-yang Mao Yuan-ji Shi Jie Zhang ming Liu zheng-fei Hu School of Materials Science and Engineering Nanjing Institute of TechnologyNanjing211167JiangsuChina Jiangsu Key Laboratory of Advanced Structural Materials and Application Technology Nanjing211167JiangsuChina Jiangsu Wind Power Engineering Technology Center Nanjing210023JiangsuChina Nanjing Vocational University of Industry Technology Nanjing210023JiangsuChina Baoshan Iron&Steel Co. Ltd.Shanghai201900China Fujian Provincial Key Laboratory of Terahertz Functional Devices and Intelligent Sensing School of Mechanical Engineering and AutomationFuzhou UniversityFuzhou350116FujianChina School of Materials Science and Engineering Tongji UniversityShanghai201804China

The grain boundary(GB)damage of long-term crept HR3C(25Cr–20Ni–Nb–N)austenitic steel with solid solution state was investigated by nanoindentation test accompanied with in-situ electron back-scattered *** corresponding microstructure was characterized by scanning electron microscopy and transmission electron *** show that the increase in nanoindentation hardness at the GBs and triple grain junctions may be related to the dislocation accumulation and carbide growth during the *** M23C6 and dislocations piling-up at the GB accelerate the nucleation and coalescence of creep cavity along the *** nanoindentation hardness in grains varies with orientation of the stress *** orientation difference of neighbor grains may induce local high geometrically necessary dislocation densities and strain gradients near the GB,consequently causing stress concentration and subsequent crack growth at specific GBs.

关键词： Austenitic steel Creep Nanoindentation Grain orientation Creep-induced cracking

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Engineering neuroregenerative microenvironment via aligned hydrogel-assisted magnetic stimulation for complete spinal cord injury repair

引用

Engineered Regeneration 2024年第2期5卷 139-152页

作者： Chun-Yi Yang zhe Meng Zhijun He Pengchao Ma Zhaohui hou Kunkoo Kim Jingsong Lu Kaiyuan Yang Guihuai Wang Xiumei Wang State Key Laboratory of New Ceramics and Fine Processing Key Laboratory of Advanced Materials of Ministry of EducationSchool of Materials Science and EngineeringTsinghua UniversityBeijing 100084China Department of Neurosurgery Beijing Tsinghua Changgung HospitalSchool of Clinical MedicineTsinghua UniversityBeijing102218China

Utilizing biomaterials in tissue engineering has shown considerable promise for tissue regeneration,particularly through delivering multimodel cell-regulatory signals,including the material-related signals and extrinsic *** this research,we developed a magnetic-responsive aligned nanofiber fibrin hydrogel(MAFG),integrating the structured alignment of nanofibers and the pliability of fibrin hydrogel with an external magnetic *** design aimed to enhance the regenerative response in spinal cord injury treatment.A medium-strength magnetic field,aligned with the spinal cord,was applied to aid motor function recovery in rats with spinal cord *** use of MAFG in this context not only intensified the effect of the magnetic field but also encouraged the activation and differentiation of native neural stem ***,this method effectively steered macrophage polarization towards a beneficial M2 phenotype,addressing immune dysregulation at the injury *** parallel application of magnetic field stimulation through MAFG in a spinal cord injury model contributed to the concurrent promotion of neurogenesis,angiogenesis,and immunomodulation,resulting in marked improvement in motor function in *** investigation underscores the therapeutic potential of magnetic field stimulation and highlights how aligning this stimulation with the spinal cord can significantly enhance the regenerative milieu at the injury site.

关键词： Angiogenesis Neurogenesis Immunomodulation Magnetic-responsive hydrogel Magnetic stimulation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Lower synaptic density and its association with cognitive dysfunction in patients with obsessive-compulsive disorder

引用

General Psychiatry 2024年第3期37卷 422-430页

作者： Qian Xiao Jiale hou Ling Xiao ming Zhou Zhiyou He Huixi Dong Shuo Hu Mental Health Center Xiangya HospitalCentral South UniversityChangshaHunanChina Department of Nuclear Medicine Xiangya HospitalCentral South UniversityChangshaHunanChina Key Laboratory of Biological Nanotechnology National Health CommissionChangshaHunanChina National Clinical Research Center Geriatric Disorders(Xiangya)ChangshaHunanChina

Background Understanding synaptic alteration in obsessive-compulsive disorder(OCD)is crucial for elucidating its pathological mechanisms,but in vivo research on this topic remains *** This study aimed to identify the synaptic density indicators in OCD and explore the relationship between cognitive dysfunction and synaptic density changes in *** This study enrolled 28 drug-naive adults with OCD aged 18-40 years and 16 healthy controls(HCs).Three-dimensional T1-weighted structural magnetic resonance imaging and 18F-SynVesT-1 positron emission tomography were *** function was assessed using the Wisconsin Cart Sorting Test(WCST)in patients with OCD and *** analysis was performed to examine the association between synaptic density reduction and cognitive *** Compared with HCs,patients with OCD showed reduced synaptic density in regions of the cortico-striatothalamo-cortical circuit such as the bilateral putamen,left caudate,left parahippocampal gyrus,left insula,left parahippocampal gyrus and left middle occipital lobe(voxel p<0.001,uncorrected,with cluster level above 50 contiguous voxels).The per cent conceptual-level responses of WCST were positively associated with the synaptic density reduction in the left middle occipital gyrus(R^(2)=0.1690,p=0.030),left parahippocampal gyrus(R^(2)=0.1464,p=0.045)and left putamen(R^(2)=0.1967,p=0.018)in patients with *** Adults with OCD demonstrated lower 18Flabelled difluoro analogue of 18F-SynVesT-1 compared with HCs,indicating potentially lower synaptic *** is the first study to explore the synaptic density in patients with OCD and provides insights into potential biological targets for cognitive dysfunctions in OCD.

关键词： patients dysfunction Lower

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

CrN supported by carbon nanosheets as efficient catalysts toward oxygen reduction reaction and Zn-air batteries

引用

Rare Metals 2024年第10期43卷 4973-4981页

作者： Ya-Ting Zhang Fan Zhang zhe Lu Jun-ming Luo Su-Yang Feng Qi Wang Hui Chen Hao-ming Wu zheng-Pei Miao Bin Chi Neng Yu Cheng-Hang You Jing Li Xin-Long Tian School of Chemistry and Chemical Engineering School of Marine Science and EngineeringHainan Provincial Key Lab of Fine ChemistryHainan University State Power Investment Group Hainan Electric Power Co.Ltd. Key Laboratory of Fuel Cell Technology of Guangdong Province Shenzhen Automotive Research Institute Beijing Institute of Technology State Key Laboratory of Nuclear Resources and Environment East China University of Technology

Exploring non-precious efficient oxygen reduction reaction （ORR） catalysts is of great significance to fuel cells and Zn-air batteries （ZABs）.CrN is a theoretically promising ORR catalyst,but its potential needs to be unlocked by proper supports that provide high conductivity and high exposure of active *** this work,we introduce a novel synthesis of carbon nanosheets-supported CrN nanoparticles （CrN/C） by annealing the mixture of CrCl3,1,10-phenanthroline and melamine via a two-step *** prepared CrN/C materials show good ORR activity and stability in acidic and alkaline *** optimal CrN/C material has an ORR half-wave potential of 0.73 and 0.72 V （*** hydrogen electrode） in acidic and alkaline media,*** it retains 82% and 78% of ORR current density in acidic and alkaline media after durability tests,***,the optimal CrN/C material-based self-breathing ZABs deliver a maximum power density of 168 mW·cm-2,which is one of the highest among transition metal nitrides-based ZABs It is found that the ORR activity of CrN/C materials is highly related to the Cr–N valence *** work highlights the good potential of CrN as robust ORR catalyst and verifies its promising application in ZABs.

关键词： Carbon nanosheets CrN Fuel cells Oxygen reduction reaction Zn-air batteries

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Notopterygium Incisum Extract Promotes Apoptosis by Preventing the Degradation of BIM in Colorectal Cancer

引用

Current Medical Science 2024年第4期44卷 833-840页

作者： Jun-he CHEN Cheng-ming WEI Qian-yu LIN Zi WANG Fu-ming ZHANG Mei-na SHI Wen-jian LAN Chang-gang SUN Wan-jun LIN Wen-zhe MA State Key Laboratory of Quality Research in Chinese Medicine Macao University of Science and TechnologyMacao999078China School of Pharmaceutical Sciences Sun Yat-sen UniversityGuangzhou510006China College of Traditional Chinese Medicine Weifang Medical UniversityWeifang261053China

Objective Colorectal cancer(CRC),a prevalent malignancy worldwide,has prompted extensive research into anticancer *** Chinese medicinal materials offer promising avenues for cancer management due to their diverse pharmacological *** study investigated the effects of Notopterygium incisum,a traditional Chinese medicine named Qianghuo(QH),on CRC cells and the underlying *** The sulforhodamine B assay and colony formation assay were employed to assess the effect of QH extract on the proliferation of CRC cell lines HCT116 and *** iodide(PI)staining was utilized to detect cell cycle progression,and PE Annexin V staining to detect *** blotting was conducted to examine the levels of apoptotic proteins,including B-cell lymphoma 2-interacting mediator of cell death(BIM),B-cell lymphoma 2(Bcl-2),Bcl-2-associated X protein(BAX)and cleaved caspase-3,as well as BIM stability after treatment with the protein synthesis inhibitor *** expression of BAX was suppressed using lentivirus-mediated shRNA to validate the involvement of the BIM/BAX axis in QH-induced *** in vivo effects of QH extract on tumor growth were observed using a xenograft ***,APC^(Min+)mice were used to study the effects of QH extract on primary intestinal *** QH extract exhibited significant in vitro anti-CRC activities evidenced by the inhibition of cell proliferation,perturbation of cell cycle progression,and induction of ***,QH extract significantly increased the stability of BIM proteins,which undergo rapid degradation under unstressed *** of BAX,the downstream effector of BIM,significantly rescued QH-induced ***,the in vitro effect of QH extract was recapitulated in *** extract significantly inhibited the tumor growth of HCT116 xenografts in nude mice and decreased the number of intestinal polyps in the APC^(Min+)*** QH extract

关键词： Notopterygium incisum colorectal cancer apoptosis B-cell lymphoma 2-interacting mediator of cell death

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Integrated Chinese and Western Medicine in Treatment of Bronchopleural Fistula with Mycobacterium abscessus:A Case Report

引用

Chinese Journal of Integrative Medicine 2024年第8期30卷 742-746页

作者： WANG Qian-yun CHENG Miao BAN Cheng-jun ZHANG Li-shan WANG Hong-wu YANG Bing ZOU Heng WANG ming-zhe The First Clinical Medical College of Beijing University of Chinese Medicine Beijing100700China Department of Respiratory Dongzhimen HospitalBeijing University of Chinese MedicineBeijing100700China

Bronchopleural fistula(BPF)is defined as a pathological connection between the trachea or bronchus and the pleural *** may occur as a serious complication after lung surgery.^((1))It has a low incidence of 1%-3%^((2.3... 详细信息

关键词： pleural lung surgery

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Interaction mechanism between BaZrO_(3)/Y_(2)O_(3) refractory and Ti_(2)Ni alloy melts

引用

Journal of Iron and Steel Research International 2024年第6期31卷 1376-1388页

作者： Xiao hou Guang-yao Chen Jian Liu ming-rui Lv Fei-hai Yu Qi-sheng Feng Rong-bin Li Xiong-gang Lu Chong-he Li State Key Laboratory of Advanced Special Steel and Shanghai Key Laboratory of Advanced Ferromeallurgy and School of Materials Science and Engineering Shanghai UniversityShanghai 200072China Shanghai Special Casting Engineering Technology Research Center Shanghai 201605China zhejiang Institute of Advanced Materials Shanghai UniversityJiashan 314100ZhejiangChina School of Materials Science and Engineering Shanghai DianJi UniversityShanghai 201306China

The titanium alloys with highly chemical activity require stable crucible refractories that can withstand the erosion of alloy *** phase composition and microstructure are crucial factors that affect the stability of the refractory *** effect of Y_(2)O_(3) on the composition and microstructure of BaZrO_(3) crucible was systematically investigated,and the improved mechanism of the stability of BaZrO_(3)/Y_(2)O_(3) crucible was clarified in comparison with the BaZrO_(3) *** results showed that the erosion layer thickness of the BaZrO_(3)/Y_(2)O_(3) crucible was only 63μm,which was far less than that in the BaZrO_(3) crucible(485μm),and the erosion layer in the BaZrO_(3)/Y_(2)O_(3) crucible also exhibited a higher density than that in the BaZrO_(3) *** the sintering,Y_(2)O_(3) could improve the densification of the BaZrO_(3) crucible due to the solid solution effect between Y_(2)O_(3) and ZrO_(2),which also caused the evaporation of BaO,resulting in the generation of a Y_(2)O_(3)(ZrO_(2))film on the surface of the ***,the Y_(2)O_(3)(ZrO_(2))had higher thermodynamic stability than Y_(2)O_(3),confirming that the BaZrO_(3)/Y_(2)O_(3) crucible with high density exhibited a superior erosion resistance to titanium *** dual-phase structure provides a strategy to design a long-life and stable refractory for melting titanium alloys.

关键词： Barium zirconate Yttrium oxide Dual-phase refractory Titanium alloy Interaction

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A novel profile modification HPF-Co gel satisfied with fractured low permeability reservoirs in high temperature and high salinity

引用

Petroleum Science 2024年第1期21卷 683-693页

作者： Ya-Kai Li Ji-Rui hou Wei-Peng Wu ming Qu Tuo Liang Wei-Xin Zhong Yu-Chen Wen Hai-Tong Sun Yi-Nuo Pan China University of Petroleum Beijing Beijing102249China PetroChina Tarim Oilfield Company Korla 841000XinjiangChina Key Laboratory of Improving Oil and Gas Recovery of Ministry of Education Northeast Petroleum University Daqing 163318HeilongjiangChina Xi'an Shiyou University Xi'an 710065ShaanxiChina Northwest Oilfield Company SINOPECUrumqi 830011XinjiangChina

Conformance control and water plugging are a widely used EOR method in mature ***,majority of conformance control and water plugging agents are unavoidable dehydrated situation in high-temperature and high-salinity low permeability ***,a novel conformance control system HPF-Co gel,based on high-temperature stabilizer(CoCl_(2)·H_(2)O,CCH)is *** HPF-Co bulk gel has better performances with high temperature(120℃)and high salinity(1×10^(5)mg/L).According to Sydansk coding system,the gel strength of HPF-Co with CCH is increased to code *** dehydration rate of HPF-Co gel is 32.0%after aging for 150 d at 120℃,showing excellent thermal *** rheological properties of HPF gel and HPF-Co gel are also *** results show that the storage modulus(G′)of HPF-Co gel is always greater than that of HPF *** effect of CCH on the microstructure of the gel is *** results show that the HPF-Co gel with CCH has a denser gel network,and the diameter of the three-dimensional network skeleton is 1.5-3.5μ*** 90 d of aging,HPF-Co gel still has a good three-dimensional *** spectroscopy results show that CCH forms coordination bonds with N and O atoms in the gel amide group,which can suppress the vibration of cross-linked sites and improve the stability at high *** core plugging test determines the optimized polymer gel injection strategy and injection velocity with HPF-Co bulk gel system,plugging rate exceeding 98%.Moreover,the results of subsequent waterflooding recovery can be improved by 17%.

关键词： Low permeability reservoir High-temperature resistant gel Complexation reaction Polymer gel injection strategy Plugging rate Enhanced oil recovery

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：