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World Journal of Gastroenterology 2004年第4期10卷 476-480页

作者： ming-YaoWu chu-XiangZhuang Huan-XingYang Ying-Ruiliang DepartmentofPathology ShantouUniversityMedicalCollegeShantou515031GuangdongProvinceChina DepartmentofPhysiology ShantouUniversityMedicalCollegeShantou515031GuangdongProvinceChina DepartmentofPathology TheFirstPeople'sHospitalofFoshanFoshan528000GuangdongProvinceChina

AIM:To examine the expression of Egr-1, c-fos and cyclin D1 at both transcript and protein levels in esophageal carcinoma and to correlate the level of their expressions with precancerous and paracancerous esophageal lesions and esophageal ***:In situ hybridization and immunohistochemistry were used respectively to detect the expression of mRNA and proteins of Egr-1, c-fos and cyclin D1 in 70 cases of esophageal squamous cell carcinoma and their corresponding para-cancerous mucosa and upper cut edge ***:In situ hybridization and immunohistochemistry showed positive staining of all three mRNAs in the cytoplasm and those of the proteins in nuclei. Overexpression of Egr-1, c-los and cyclin D1 mRNAs and their proteins was found in dysplasia and squamous carcinomas. The expression level of Egr-1 and c-los was high, and cyclin D1 was low in dysplasia mucosa, whereas the expression of Egr-1 was decreased, c-fos was maintained and cyclin D1 was increased in the cancers. The expression of both c-fos and cyclinD1 was consistent between the mRNA and protein in their corresponding high expression ***: The expression of Egr-1, c-fos and cyclin D1 varies in esophageal precancerous lesions and cancer tissues, suggesting an involvement of these genes in the development of esophageal carcinoma.

关键词：食管癌细胞因子免疫组织化学癌前病变 Egr-1 c-fos cyclin D1

A New Method for Determining Fluid Compositions in the H_2O-NaClCaCl_2 System with Cryogenic Raman Spectroscopy

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Acta Geologica Sinica(English Edition) 2014年第4期88卷 1169-1182页

作者： CHI Guoxiang chu Haixia Ryan SCOTT CHOU I-ming Department of Geology University of Regina Laboratory for Experimental Study Under Deep-sea Extreme Conditions Sanya Institute of Deep-sea Science and EngineeringChinese Academy of Sciences

Raman peaks of various hydrates in the H20-NaCl-CaCl2 system have been previously identified, but a quantitative relationship between the Raman peaks and XNaCl （i.e.,NaCl/ （NaCl＋CaCl2）） has not been established, mainly due to the difficulty to freeze the solutions. This problem was solved by adding alumina powder to the solutions to facilitate nucleation of crystals. Cryogenic （-185℃） Raman spectroscopic studies of alumina-spiced solutions indicate that XNaCl is linearly correlated with the total peak area fraction of hydrohalite. Capsules of solutions made from silica capillary were prepared to simulate fluid inclusions. Most of these artificial fluid inclusions could not be totally frozen even at temperatures as low as -185℃, and the total peak area fraction of hydrohalite is not correlated linearly with XNaCI. However, the degree of deviation （△XNaCl） from the linear correlation established earlier is related to the amount of residual solution, which is reflected by the ratio （r） of the baseline ＂bump＂ area, resulting from the interstitial unfrozen brine near 3435 cm^-1, and the total hydrate peak area between 3350 and 3600 cm^-1. A linear correlation between △XNaCl and r is established to estimate XNaCl from cryogenic Raman spectroscopic analysis for fluid inclusions.

关键词： cryogenic Raman H20-NaCl-CaCl2 XNaCI fluid inclusion

Estimation of peak relative velocity and peak absolute acceleration of linear SDOF systems

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Earthquake Engineering and Engineering Vibration 2007年第2期6卷 1-10页

作者： Jianwei Song Yi-Lun chu Zach liang George C. Lee Department of Civil Structural and Environmental Engineering University at Buffalo State University of New York USA

In the seismic analysis and design of structures, the true velocity and absolute acceleration are usually approximated by their corresponding pseudo-values. This approach is simple and works well for structures with small damping （say, less than 15%）. When the damping of a structure is enhanced for the purpose of response reduction, it may result in large analysis and design errors. Based on theory of random vibration and the established mechanism of seismic response spectra analysis, a method is developed （1） to predict the relative velocity spectra with any damping ratio level directly from the 5% standard pseudo-acceleration spectrum; and （2） to estimate the peak absolute acceleration. The accuracy of both is validated by using two selected ensembles of ground motion records.

关键词： damping device velocity spectrum absolute acceleration spectrum response spectrum analysis

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A multi-class large margin classifier

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2009年第2期10卷 253-262页

作者： liang TANG Qi XUAN Rong XIONG Tie-jun WU Jian chu Institute of Cyber-Systems and Control Zhejiang University Hangzhou 310027 China

Currently there are two approaches for a multi-class support vector classifier(SVC). One is to construct and combine several binary classifiers while the other is to directly consider all classes of data in one optimization formulation. For a K-class problem(K>2),the first approach has to construct at least K classifiers,and the second approach has to solve a much larger op-timization problem proportional to K by the algorithms developed so far. In this paper,following the second approach,we present a novel multi-class large margin classifier(MLMC). This new machine can solve K-class problems in one optimization formula-tion without increasing the size of the quadratic programming(QP) problem proportional to K. This property allows us to construct just one classifier with as few variables in the QP problem as possible to classify multi-class data,and we can gain the advantage of speed from it especially when K is large. Our experiments indicate that MLMC almost works as well as(sometimes better than) many other multi-class SVCs for some benchmark data classification problems,and obtains a reasonable performance in face recognition application on the AR face database.

关键词： Multi-classification Support vector machine (SVM) Quadratic programming (QP) problem Large margin

Novel Model of Proton Exchange Membrane Fuel Cell with Predictive Control Using Hildreth Algorithm Based on Fractional-order Dynamic Model

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China Petroleum Processing & Petrochemical Technology 2024年第3期26卷 122-135页

作者： chu Kaihui Qi Zhidong Qin Hao Shan liang School of Automation Nanjing University of Science and TechnologyNanjing 210094China

Considering the multivariable and fractional-order characteristics of proton exchange membrane fuel cells(PEMFCs),a fractional-order subspace identification method(FOSIM)is proposed in this paper to establish a fractionalorder state space(FOSS)model,which can be expressed as a multivariable configuration with two inputs,hydrogenflow rate and stack current,and two outputs,cell voltage and *** on this model,a novel constrained optimal control law named the Hildreth model predictive control(H-MPC)strategy is created,which employs a Hildreth quadratic programming algorithm to adjust the output power of fuel cells through adaptively regulating hydrogen flow and stack *** semi-physical simulation results demonstrate that,compared with proportional-integral-derivative and quadratic programming MPC(QP-MPC),the proposed H-MPC exhibits better tracking ability and strong robustness against variations of PEMFC power.

关键词： PEMFC fractional-order subspace identification method fractional-order state space H-MPC

New Computation of Unified Bounds via a More General Fractional Operator Using Generalized Mittag-Leffler Function in the Kernel

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Computer Modeling in Engineering & Sciences 2021年第1期126卷 359-378页

作者： Saima Rashid Zakia Hammouch Rehana Ashraf Yu-ming chu Department of Mathematics Government College UniversityFaisalabadPakistan Division of Applied mathematics Thu Dau Mot UniversityThu Dau Mot CityVietnam Department of Mathematics Lahore CollegeWomen UniversityJhangh CampusLahorePakistan Department of Mathematics Huzhou UniversityHuzhouChina

In the present case,we propose the novel generalized fractional integral operator describing Mittag-Leffler function in their kernel with respect to another function Φ.The proposed technique is to use graceful amalgamations of the Riemann-Liouville(RL)fractional integral operator and several other fractional ***,several generalizations are considered in order to demonstrate the novel variants involving a family of positive functions n(n∈N)for the proposed fractional *** order to confirm and demonstrate the proficiency of the characterized strategy,we analyze existing fractional integral operators in terms of classical fractional ***,some special cases are apprehended and the new outcomes are also *** obtained consequences illuminate that future research is easy to implement,profoundly efficient,viable,and exceptionally precise in its investigation of the behavior of non-linear differential equations of fractional order that emerge in the associated areas of science and engineering.

关键词： Integral inequality generalized fractional integral with respect to another function increasing and decreasing functions Mittag-Leffler function

Peak earthquake response of structures under multi-component excitations

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Earthquake Engineering and Engineering Vibration 2007年第4期6卷 357-370页

作者： Jianwei Song Zach liang Yi-Lun chu George C. Lee Department of Civil Structural and Environmental Engineering State University of New York at Buffalo USA

Accurate estimation of the peak seismic responses of structures is important in earthquake resistant design. The internal force distributions and the seismic responses of structures are quite complex, since ground motions are multidirectional. One key issue is the uncertainty of the incident angle between the directions of ground motion and the reference axes of the structure. Different assumed seismic incidences can result in different peak values within the scope of design spectrum analysis for a given structure and earthquake ground motion record combination. Using time history analysis to determine the maximum structural responses excited by a given earthquake record requires repetitive calculations to determine the critical incident angle. This paper presents a transformation approach for relatively accurate and rapid determination of the maximum peak responses of a linear structure subjected to three-dimensional excitations within all possible seismic incident angles. The responses can be deformations, internal forces, strains and so on. An irregular building structure model is established using SAP2000 program. Several typical earthquake records and an artificial white noise are applied to the structure model to illustrate the variation of the maximum structural responses for different incident angles. Numerical results show that for many structural parameters, the variation can be greater than 100%. This method can be directly applied to time history analysis of structures using existing computer software to determine the peak responses without carrying out the analyses for all possible incident angles. It can also be used to verify and/or modify aseismic designs by using response spectrum analysis.

关键词： multi-component ground motion time history analysis peak structural response axis rotation

MHD simulations of inward shocks in Cassiopeia A

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Research in Astronomy and Astrophysics 2020年第4期20卷 39-43页

作者： chu-Yuan Yang Bi-Wen Bao Si-ming Liu Yunnan Observatories Chinese Academy of SciencesKunming 650216China Key Laboratory for the Structure and Evolution of Celestial Objects Chinese Academy of SciencesKunming 650216China Center for Astronomical Mega-Science Chinese Academy of SciencesBeijing 100101China Department of Astronomy Key Laboratory of Astroparticle Physics of Yunnan ProvinceYunnan UniversityKunming 650091China Key Laboratory of Dark Matter and Space Astronomy Purple Mountain ObservatoryChinese Academy of SciencesNanjing 210033China

Cassiopeia A,the brightest radio supernova remnant(SNR)in the sky,has several unique characteristics in comparison to its *** its radio brightness and prominent soft-concave radio spectrum,itsγ-ray spectrum appears to have a low-energy cutoff near 2 GeV,and it is the only SNR with prominent hard X-ray *** the unusual radio properties may be attributed to strong emission from reverse shocks,the hard X-ray emission has been associated with high-speed inward shocks induced by high density ***,the low-energyγ-ray spectral cutoff could be attributed to slow penetration of lower energy particles accelerated near the inward shocks into high-density emission *** this paper,we carry out magneto-hydrodynamic(MHD)simulations of shocks in Cassiopeia A and demonstrate that its inward shock structure can indeed be reproduced via shock interactions with clumps of gases with a density of 20 cm-3.

关键词： acceleration of particles supernovae:individual(Cassiopeia A) ISM:supernova remnants X-rays:ISM

Mechanism,Kinetics,and Thermodynamic Characteristics for the Demetallization of Used Lubricating Oil via Pyrolysis

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China Petroleum Processing & Petrochemical Technology 2023年第2期25卷 113-127页

作者： Yang Haiyu Jiang Zhenxin chu Qingyan Jiang Peng Wang ming School of Chemistry and Chemical Engineering Shandong University of TechnologyZibo 255049China Shandong Qinghe Chemical Technology Co. LtdZibo 256405China School of Chemistry and Chemical Engineering Qingdao UniversityQingdao 266071China

This study analyzed the pyrolysis mechanism,developed a pyrolysis kinetic model,and determined the corresponding thermodynamic parameters for the removal of calcium from used lubricating oil using sulfurized calcium alkyl phenolate(T-115B)as a model *** pyrolysis process and products were evaluated by Fourier transform infrared spectroscopy and X-ray photoelectron *** inspection indicated that the removal of calcium from T-115B depended primarily on the destruction of micelles caused by the pyrolysis of compounds at high *** pyrolysis characteristics of T-115B at different heating rates were investigated by thermogravimetry and differential thermal analysis,which revealed two distinct pyrolysis ***,the pyrolysis mechanism can be described by a twostep *** activation energy and thermodynamic parameters(ΔH,ΔG,andΔS)were determined by applying the Kissinger-Akahira-Sunose,Flynn-Wall-Ozawa,Friedman,and Starink methods;the average activation energies for T-115B pyrolysis obtained using these methods were 115.80,119.84,124.96,and 116.14 kJ/mol,***,both stages of the pyrolysis reaction followed Fn mechanisms with n=1.39 in the first stage and n=0.86 in the second *** study provides reliable and effective pyrolysis models along with kinetic and thermodynamic parameters to facilitate the largescale industrial application of used lubricating oil.

关键词： used lubricating oil sulfurized calcium alkyl phenolate pyrolysis decomposition kinetics thermodynamics non-isothermal method

Up-regulation of calmodulin involved in the stress response to cyantraniliprole in the whitefly, Bemisia tabaci (Hemiptera: Aleyrodidae)

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Insect Science 2021年第6期28卷 1745-1755页

作者： Lei Guo Changyou Li Grey Coupland Pei liang Dong chu Key Lab of Integrated Crop Pest Management of Shandong Province College of Plant Health and MedicineQingdao Agricultural UniversityQingdaoShangdong266109China Harry Butler Institute Murdoch UniversityMurdochWA6150Australia Department of Entomology College of Plant ProtectionChina Agricultural UniversityBeijing100193China

Cyantraniliprole is the first diamide insecticide to have cross-spectrum activity against a broad range of insect *** insecticide,like other diamides,selectively acts on ryanodine receptor,destroys Ca^(2+) homeostasis,and ultimately causes insect *** expression regulations of genes associated with calcium signaling pathways are known to be involved in the response to diamides,little is known regarding the function of calmodulin(CaM),a typical Ca^(2+)sensor central in regulating Ca^(2+) homeostasis,in the stress response of insects to the *** this study,we cloned and identified the full-length complementary DNA of CaM in the whitefly,Bemisia tabaci(Gennadius),named *** real-time reverse transcription polymerase chain reaction-based analyses showed that the messenger RNA level of BtCaM was rapidly induced from l.5l-to 2.43-fold by cyantraniliprole during 24 *** of BtCaM by RNA interference increased the toxicity of cyantraniliprole in whiteflies by 42.85%.In contrast,BtCaM expression in Sf9 cells significantly increased the cells,tolerance to cyantraniliprole as much as *** addition,the expression of BtCaM in Sf9 cells suppressed the rapid increase of intracellular Ca^(2+) after exposure to cyantraniliprole,and the maximum amplitude in the Sf9-BtCaM cells was only 34.9%of that in control cells(Sf9-PIZ/V5).These results demonstrate that overexpression of BtCaM is involved in the stress response of *** to cyantraniliprole through regulation of Ca^(2+)*** CaM is one of the most evolutionarily conserved Ca^(2+) sensors in insects,outcomes of this study may provide the first details of a universal insect response to diamide insecticides.

关键词： Bemisia tabaci Ca^(2+)homeostasis calmodulin cyantraniliprole insecticide stress overexpression