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Giant Goos–Hnchen shifts of waveguide coupled long-range surface plasmon resonance mode

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Chinese Physics B 2018年第8期27卷 30-34页

作者： Qi You jia-Qi Zhu ]un Guo lei-ming wu Xiao-Yu Dai Yuan-Jiang Xiang SZU-NUS Collaborative Innovation Center for Optoelectronic Science ＆ Technology Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province College of Optoelectronic EngineeringShenzhen UniversityShenzhen 518060China

A hybrid structure based on a planar waveguide （PWG） mode coupling a long-range surface plasmon resonance （LRSPR） mode is proposed to enhance the GH shift. Both the PWG mode and LRSPR mode can be in strong resonance, and these two modes can be coupled together due to the normal-mode splitting. The largest GH shift of PWG-coupled LRSPR structure is 4156 times that of the incident beam, which is 23 times and 3.6 times that of the surface plasmon resonance （SPR） structure and the LRSPR structure, respectively. As a GH shift sensor, the highest sensitivity of 4.68 x 107 λ is realized in the coupled structure. Compared with the sensitivity of the traditional SPR structure, the sensitivity of our structure is increased by more than 2 orders, which theoretically indicates that the proposed configuration can be applied to the field of high-sensitivity sensors in the future.

关键词： Goos-Hfinchen (GH) shift planar waveguide (PWG) long-range surface plasmon polartons (LR-SPPs)

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大众武术健身状况及对策研究

广州体育学院学报 2017年第4期37卷 68-71页

作者：明磊刘文武上海师范大学体育学院上海200234 上海体育学院武术学院上海200438

来自于实践和理论两个方面的诸多证据表明,武术在当代大众健身场域中的发展状况堪忧。针对此一问题,综合运用文献法、访谈法、观察法,尝试对大众武术健身的特点、问题及其产生原因、解决对策,展开新的探讨。研究认为:大众健身与学校教... 详细信息

来自于实践和理论两个方面的诸多证据表明,武术在当代大众健身场域中的发展状况堪忧。针对此一问题,综合运用文献法、访谈法、观察法,尝试对大众武术健身的特点、问题及其产生原因、解决对策,展开新的探讨。研究认为:大众健身与学校教育、运动竞赛相比,具有个体自觉参与和遵循市场规律两个突出特点;大众武术健身发展窘况的产生,一方面源于时代发展的必然,从内因上讲,则由于向大众群体提供的武术"产品"与其需求错位,以及武术自身运动特点的局限性所致;由此提出三条发展对策:1)摆正位置——武术健身的自知之明,2)突出优长——武术健身的路径选择,3)老年群体——武术健身的靶人群。

关键词：武术大众健身心理需求

从药物临床试验数据核查看伦理委员会的职责履行情况

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中国新药杂志 2019年第20期28卷 2513-2517页

作者：高荣唐静方翔雷明武张琼光国家药品监督管理局食品药品查验中心

伦理委员会(ethics committee,EC)作为药物临床试验方案及相关文件的审查者、受试者权益的保护者,在药物临床试验中发挥着重要作用。本文根据《药物临床试验质量管理规范》(good clinical practice,GCP)和《药物临床试验伦理审查工作指... 详细信息

伦理委员会(ethics committee,EC)作为药物临床试验方案及相关文件的审查者、受试者权益的保护者,在药物临床试验中发挥着重要作用。本文根据《药物临床试验质量管理规范》(good clinical practice,GCP)和《药物临床试验伦理审查工作指导原则》的相关规定及药物临床试验监督检查新形势下对伦理委员会的职责要求,结合药物临床试验数据核查中伦理委员会存在的常见问题,对伦理委员会应履行的职责进行分析和探讨。

关键词：药物临床试验药物临床试验质量管理规范数据核查伦理委员会职责

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Dynamic Regulation of Hydrogen Bonding Networks and Solvation Structures for Synergistic Solar‑Thermal Desalination of Seawater and Catalytic Degradation of Organic Pollutants

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Nano-Micro Letters 2025年第2期17卷 548-565页

作者： ming‑Yuan Yu Jing wu Guang Yin Fan‑Zhen Jiao Zhong‑Zhen Yu Jin Qu Beijing Key Laboratory of Advanced Functional Polymer Composites Beijing University of Chemical TechnologyBeijing 100029People’s Republic of China State Key Laboratory of Organic‑Inorganic Composites College of Materials Science and EngineeringBeijing University of Chemical TechnologyBeijing 100029People’s Republic of China

Although solar steam generation strategy is efficient in desalinating seawater,it is still challenging to achieve continuous solar-thermal desalination of seawater and catalytic degradation of organic ***,dynamic regulations of hydrogen bonding networks and solvation structures are realized by designing an asymmetric bilayer membrane consisting of a bacterial cellulose/carbon nanotube/Co_(2)(OH)_(2)CO_(3)nanorod top layer and a bacterial cellulose/Co_(2)(OH)_(2)CO_(3)nanorod(BCH)bottom ***,the hydrogen bonding networks inside the membrane can be tuned by the rich surface–OH groups of the bacterial cellulose and Co_(2)(OH)_(2)CO_(3)as well as the ions and radicals in situ generated during the catalysis ***,both SO_(4)^(2−)and HSO_(5)−can regulate the solvation structure of Na^(+)and be adsorbed more preferentially on the evaporation surface than Cl^(−),thus hindering the de-solvation of the solvated Na^(+)and subsequent nucleation/growth of ***,the heat generated by the solar-thermal energy conversion can accelerate the reaction kinetics and enhance the catalytic degradation *** work provides a flow-bed water purification system with an asymmetric solar-thermal and catalytic membrane for synergistic solar thermal desalination of seawater/brine and catalytic degradation of organic pollutants.

关键词： Solar steam generation Seawater desalination Catalytic degradation Bacterial cellulose Cobalt hydroxycarbonate nanorods

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用于蓝宝石光盘的数字化数据存储

光学精密工程 2016年第10期24卷 2456-2461页

作者：付明磊徐武超乐孜纯伊凡.高博夫德米特罗.曼科浙江工业大学理学院浙江杭州310023 浙江工业大学义乌科学技术研究院浙江义乌322001 乌克兰国家科学院信息记录研究所乌克兰基辅03113

为了解决长时数据存储的难题,开展了以数字格式在蓝宝石光盘表面写入数据的研究工作。根据艾林方程,分析了利用常用无机材料进行数据存储的数据失效时间。描述了在蓝宝石材料为基底的光盘上以数字格式记录数据的基本工艺流程,重点介绍... 详细信息

为了解决长时数据存储的难题,开展了以数字格式在蓝宝石光盘表面写入数据的研究工作。根据艾林方程,分析了利用常用无机材料进行数据存储的数据失效时间。描述了在蓝宝石材料为基底的光盘上以数字格式记录数据的基本工艺流程,重点介绍了用于蓝宝石光盘的离子束刻蚀系统。实验结果显示,蓝宝石光盘表面刻蚀的信息坑宽度为0.6μm,深度为0.2μm,磁道节距为1.6μm,符合ISO/IEC 10149:1995规定的CD-ROM格式数据存储要求,表明采用本文提出的方法实现蓝宝石光盘的数字化数据存储是可行的。此外,这种基本工艺流程不仅适用于蓝宝石光盘,同样适用于其它以高度稳定的材料(如石英玻璃)作为基底的光盘。

关键词：蓝宝石光盘光学数据存储长时数据存储干法刻蚀

从药物临床试验数据核查看研究者的职责履行情况

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中国新药杂志 2019年第20期28卷 2508-2512页

作者：高荣吕术超李秀丽雷明武钱雪国家药品监督管理局食品药品查验中心

在药物临床试验中,研究者作为实施者、临床试验质量及受试者安全权益的直接责任人,发挥着关键作用。本文根据《药物临床试验质量管理规范》(good clinical practice,GCP)的相关规定及药物临床试验监督检查新形势下对研究者的职责要求,... 详细信息

在药物临床试验中,研究者作为实施者、临床试验质量及受试者安全权益的直接责任人,发挥着关键作用。本文根据《药物临床试验质量管理规范》(good clinical practice,GCP)的相关规定及药物临床试验监督检查新形势下对研究者的职责要求,结合药物临床试验数据核查中研究者存在的常见问题,对研究者在临床试验中应履行的职责进行分析和探讨。

关键词：药物临床试验药物临床试验质量管理规范数据核查研究者职责

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Enhancement of motor functional recovery in thoracic spinal cord injury: voluntary wheel running versus forced treadmill exercise

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Neural Regeneration Research 2025年第3期20卷 836-844页

作者： Do-Hun Lee Dan Cao Younghye Moon Chen Chen Nai-Kui Liu Xiao-ming Xu Wei wu Spinal Cord and Brain Injury Research Group Stark Neurosciences Research InstituteIndiana University School of MedicineIndianapolisINUSA Department of Neurological Surgery Indiana University School of MedicineIndianapolisINUSA Department of Neuroscience Baylor College of MedicineHoustonTXUSA

Spinal cord injury necessitates effective rehabilitation strategies, with exercise therapies showing promise in promoting recovery. This study investigated the impact of rehabilitation exercise on functional recovery and morphological changes following thoracic contusive spinal cord injury. After a 7-day recovery period after spinal cord injury, mice were assigned to either a trained group(10 weeks of voluntary running wheel or forced treadmill exercise) or an untrained group. Bi-weekly assessments revealed that the exercise-trained group, particularly the voluntary wheel exercise subgroup, displayed significantly improved locomotor recovery, more plasticity of dopaminergic and serotonin modulation compared with the untrained group. Additionally, exercise interventions led to gait pattern restoration and enhanced transcranial magnetic motor-evoked potentials. Despite consistent injury areas across groups, exercise training promoted terminal innervation of descending axons. In summary, voluntary wheel exercise shows promise for enhancing outcomes after thoracic contusive spinal cord injury, emphasizing the role of exercise modality in promoting recovery and morphological changes in spinal cord injuries. Our findings will influence future strategies for rehabilitation exercises, restoring functional movement after spinal cord injury.

关键词： behavioral assessment motor function neural plasticity running wheel exercise spinal cord injury treadmill exercise voluntary exercise

Perilipin-2 mediates ferroptosis in oligodendrocyte progenitor cells and myelin injury after ischemic stroke

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Neural Regeneration Research 2025年第7期20卷 2015-2028页

作者： Jian Yang Jiang wu Xueshun Xie Pengfei Xia Jinxin Lu Jiale Liu lei Bai Xiang Li Zhengquan Yu Haiying Li Department of Neurosurgery&Brain and Nerve Research Laboratory The First Affiliated Hospital of Soochow UniversitySuzhouJiangsu ProvinceChina Institute of Stroke Research Soochow UniversitySuzhouJiangsu ProvinceChina

Differentiation of oligodendrocyte progenitor cells into mature myelin-forming oligodendrocytes contributes to *** of remyelination due to oligodendrocyte progenitor cell death can result in severe nerve *** is an iron-dependent form of regulated cell death caused by membrane rupture induced by lipid peroxidation,and plays an important role in the pathological process of ischemic ***,there are few studies on oligodendrocyte progenitor cell *** analyzed transcriptome sequencing data from GEO databases and identified a role of ferroptosis in oligodendrocyte progenitor cell death and myelin injury after cerebral *** analysis suggested that perilipin-2(PLIN2)was involved in oligodendrocyte progenitor cell ***2 is a lipid storage protein and a marker of hypoxia-sensitive lipid droplet *** further investigation,we established a mouse model of cerebral ischemia/*** found significant myelin damage after cerebral ischemia,as well as oligodendrocyte progenitor cell death and increased lipid peroxidation levels around the infarct *** ferroptosis inhibitor,ferrostatin-1,rescued oligodendrocyte progenitor cell death and subsequent myelin *** also found increased PLIN2 levels in the peri-infarct area that co-localized with oligodendrocyte progenitor ***2 knockdown rescued demyelination and improved neurological *** findings suggest that targeting PLIN2 to regulate oligodendrocyte progenitor cell ferroptosis may be a potential therapeutic strategy for rescuing myelin damage after cerebral ischemia.

关键词： bioinformatics bulk RNA sequencing ferroptosis ischemic stroke myelin injury oligodendrocyte progenitor cell perilipin-2 single-cell RNA sequencing

FTIR及CLSM对转基因杨木细胞壁木质素含量及微区分布研究

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光谱学与光谱分析 2017年第11期37卷 3404-3408页

作者：刘苍伟苏明垒周贤武赵荣军吕建雄王玉荣中国林业科学研究院木材工业研究所北京100091 中国林业科学研究院林业新技术研究所北京100091

通过木质素基因工程能够有效降低杨木细胞壁木质素含量,从而改善人工林杨树作为木质纤维材料的利用现状。选取C3H基因活性抑制表达的转基因杨树和其对照组杨树为实验材料,利用傅里叶红外光谱(FTIR)技术快速表征C3H基因表达活性降低后幼... 详细信息

通过木质素基因工程能够有效降低杨木细胞壁木质素含量,从而改善人工林杨树作为木质纤维材料的利用现状。选取C3H基因活性抑制表达的转基因杨树和其对照组杨树为实验材料,利用傅里叶红外光谱(FTIR)技术快速表征C3H基因表达活性降低后幼龄杨木细胞壁木质素的含量,并结合激光共聚焦显微镜(CLSM)和组织化学染色技术原位表征木质素含量微区分布变化规律。结果表明转基因杨树与对照组杨树红外谱图的形状和特征峰数目、位置基本一致,表明C3H基因活性降低并未改变杨木细胞壁主要化学成分及结构,但I_(1 508)/I_(1 379),I_(1 508)/I_(1 425)和I_(1 508)/I_(1 740)木质素特征峰高度比值结果表明转基因杨木木质素含量下降了8.2%~9.5%,峰强度的区别说明C3H基因活性抑制表达能够改变杨木细胞壁上木质素等化学组分含量;CLSM观察发现转基因杨木木质素微区分布含量均为纤维细胞角隅>复合胞间层>次生壁,与对照组木质素呈现相同的沉积规律,且转基因杨木细胞壁木质素浓度低于对照组杨木;组织化学染色的结果同样表明杨木S单体木质素均匀分布于纤维细胞壁上,而G单体木质素微区沉积规律为纤维细胞角隅>复合胞间层>次生壁,进一步揭示了C3H基因活性的降低并没有改变转基因杨木G和S木质素单体的沉积规律,但对其纤维和导管壁上木质素单体含量分布有一定影响。

关键词：转基因杨木木质素傅里叶红外光谱激光共聚焦