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Accumulated Clinical Experiences from Successful Treatment of 1377 Severe and Critically Ill COVID-19 Cases

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Current Medical Science 2020年第4期40卷 597-601页

作者： Yong GAO Hai-bo QIU Shu ZHOU Zhen-ning WANG Jian-chu zhang Zheng-liang zhang Zhao-xin QIAN Hong-bo WANG Shi-huan YU Yi-feng LUO Ya dan WANG Zhuang liU Wei-ci WANG ming JIA li-ming zhang Yu zhang Yang JIN Yong zhang Yong liU Zi-hua ZHOU Ying SU Hui-qing li Wei-min XIAO Kai HUANG Ping HE Gang li Zhao-hui FU Shi liU Neng xing liN Fan-jun CHENG Union Hospital Tongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022China Zhongda Hospital of Souheast University Nanjing 210009China The First Affiliated Hospital of China Medical University Shenyang 110001China The Second Affiliated Hospital of Xi'an Jiaotong University Xi'an 710004China Xiangya Hospital of Zhongnan University Changsha 410008China The First Afiliated Hospital of Harbin Medical University Harbin 150001China The First Affiliated Hospital of Sun Yat-sen University Guangzhou 510080China Beijing Friendship Hospital of Capital Medical University Beijing 100050China Beijing Anzhen Hospital of Capital Medical University Beijing 100029China Beijing Chaoyang Hospital of Capital Medical University Beiing 100020China

Summary:In late December 2019,COVID-19 was firstly recognized in Wuhan,China and spread rapidly to all of the provinces of *** West Campus of Wuhan Union Hospital,the designated hospital to admit and treat the severe and critically ill COVID-19 cases,has treated a large number of such patients with great success and obtained lots of valuable experiences based on the Chinese guideline(V7.0).To standardize and share the treatment procedures of severe and critically ill cases,Wuhan Union Hospital has established a working group and formulated an operational recommendation,including the monitoring,early warning indicators,and several treatment principles for severe and critically ill *** treatment experiences may provide some constructive suggestions for treating the severe and critically ill COVID-19 cases all over the world.

关键词： 2019-nCoV COVID-19 pneumonia treatment guidelines

Semi-solid Processing of Steel-Al-7 Graphite Binding Plate

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Journal of Wuhan University of Technology(Materials Science) 2002年第3期17卷 46-49页

作者：张鹏 NorthrnJiaotongUniversity

The bonding of steel plate to Al 7graphite slurry was studied for the first time. The relationship model about preheat temperature of steel plate,solid fraction of Al 7graphite slurry, rolling speed and interfacial shear strength of bonding plate could be established by artificial neural networks *** model could be optimized with a genetic *** optimum bonding parameters are:516℃ for preheat temperature of steel plate,32.5% for solid fraction of Al 7graphite slurry and 12mm/s for rolling speed,and the largest interfacial shear strength of bonding plate is 70.6MPa.

关键词： bonding of steel plate to Al 7graphite slurry artificial neural networks genetic algorithm

Studies on the action mechanism of the antidepressant effect of [quercetin 3 - O - apiosyl （1→2） ] - rhamnosyl （ 1→6 ） - glucoside

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中国药理通讯 2005年第4期22卷 15-16页

作者： li - ming zhang Yun - feng li You - zhi zhang Ze - hui Gong Institute of Pharmacology and Toxicology Academy of Military Medical Sciences Beijing 100850

Pseudolaric acid B extracted from the Chinese medicinal herb Cortex Pseudolaricis ameliorates DNFB-induced atopic dermatitis-like skin lesions in BALB/c mice

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Traditional Medicine Research 2017年第4期2卷 169-175页

作者： Yi-Teng Wang Min zhang Mei-Lun liu li-ming zhang Hong Chen Tan li Department of Pharmacognosy and Pharmaceutics Logistics University of Chinese People’s Armed Police ForceTianjinChina Department of Science Research Logistics University of Chinese People’s Armed Police ForceTianjinChina Department of Pathogen Biology and Immunology Logistics University of Chinese People’s Armed Police ForceTianjinChina

Objective:Pseudolaric acid B(PB)is a newly identified diterpenoid isolated from Tujinpi(Cortex Pseudolaricis).In the present study,we aimed to explore the anti-inflammatory effects of PB on atopic dermatitis(AD),as well as the molecular mechanisms underlying its ***:BALB/c mice treated with 2,4-dinitrofluorobenzene were orally administered with PB(10 mg?kg-1?d-1).After evaluating the AD score,serum levels of IgE and the mRNA expression of NLRP3 inflammasome and IL-1βwere measured by EliSA and qRT-PCR ***:The results showed that PB treatment significantly ameliorated the development of AD-like clinical symptoms and effectively suppressed the infiltration of inflammatory ***,PB inhibited the expression of NLRP3 inflammasome and IL-1βin skin lesions,and downregulated serum IgE ***:The anti-inflammatory properties of PB were demonstrated using the 2,4-dinitrofluorobenzene-induced mouse model of AD-like skin *** study highlighted the potential use of PB as a novel therapeutic agent for the treatment of inflammation-associated skin diseases.

关键词： Pseudolaric acid B Atopic dermatitis Inflammation NLRP3 inflammasome

Intraoperative cardiac arrest during anesthesia： a retrospective study of 218 274 anesthetics undergoing non-cardiac surgery in a US teaching hospital

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Chinese Medical Journal 2011年第2期000卷 227-232页

作者： AN Jian-xiong li-ming zhang Erin A. Sullivan GUO Qu-lian John E Williams Department of Anesthesiology University of Pittsburgh Medical Center and School of Medicine Pittsburgh PA 15213 USA Department of Anesthesiology Xiangya Hospital of Central South University Changsha Hunan 410078 China

Background Patient safety has been gained much more attention in recent *** authors reviewed patients who had cardiac arrest in the operating rooms undergoing noncardiac surgery between January 1989 and December 2001 at the University of Pittsburgh Medical Center,*** main objectives of the study were to determine the incidence of intraoperative cardiac arrest,to identify possible causes of cardiac arrest and to explore amenable *** With approval by the University of Pittsburgh Institutional Review Board,patients experienced cardiac arrest during surgery were retrieved from medical records,surgical operation and anesthesia records and pathological reports by searching the Medical Archival Retrieval System （MARS）,a hospital electronic searching *** of cardiac arrest were collected over a period of thirteen years from the Pre byteria University Hospital （PUH）,*** We found 23 cases of intraoperative cardiac arrests occurred in 218 274 anesthesia cases （1.1 per 10 000）.Fourteen patients （60.8%） died in the operating room,leading to a mortality rate from all causes of 0.64 per 10 000 *** overall survival rate after arrest was 39% （9/23）.Half of the patients （12/23） were emergency cases with 41% survival rate （5/12）.One fourth of the arrests were trauma patients （6/23）.Most arrest patients （87%,20/23） were American Society of Anesthesiologists Physical Status （ASA PS） Ⅳ and Ⅴ,while only three patients were ASA PS-Ⅰ,Ⅱ and Ⅲ,*** case was attributable to an anesthesia-related cardiac arrest and recovered after successful *** Most intraoperative cardiac arrests were not due to anesthesia-related ***-related cardiac arrests might have a higher survival rate when compared to other possible causes of cardiac arrest in the operating room.

关键词： intraoperative cardiac arrest anesthesia-related patient safety mortality

Risk factors for operative morbidity and mortality in gastric cancer patients undergoing total gastrectomy

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World Journal of Gastroenterology 2008年第42期14卷 6560-6563页

作者： Dao-Jun Gong hao-Feng Miao Qi Bao ming Jiang li-Fang zhang Xiao-Tao Tong li Chen Department of Surgery Second Affiliated Hospital Zhejiang University College of Medicine Hangzhou 310009 Zhejiang Province China

AIM： To study the risk factors for morbidity and mortality following total gastrectomy. METHODS： We retrospectively reviewed the records of 125 consecutive patients who underwent total gastrectomy for gastric cancer at the Second Affiliated Hospital of Zhejiang University School of Medicine between January 2003 and March 2008. RESULTS： The overall morbidity rate was 20.8% （27 patients） and the mortality rate was 3.2% （4 patients）. Morbidity rates were higher in patients aged over 60 [odds ratio （OR） 4.23 （95% confidence interval （CI） 1.09 to 12.05）], with preoperative comorbidity [with vs without, OR 1.25 （95% CI 1.13 to 8.12）], when the combined resection was performed [combined resection vs total gastrectomy only, OR 2.67 （95% CI 1.58 to 5.06）]. CONCLUSION： Age, preoperative comorbidity and combined resection were with the rate of morbidity gastric cancer. independently associated after total gastrectomy for

关键词： Gastric cancer Total gastrectomy Morbidity Mortality Risk factor

Application HTP Process to Produce X80 Strip for 2nd West-East Gas Pipeline Project

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Journal of Iron and Steel Research International 2011年第S1期18卷 471-477页

作者： li Yong-dong 1,li ming 2,zhang Yong-qing 1,JIN Wei 2,liU Jian-hui 2,li Fei 1 (1.Shougang Research Institute of Technology,Beijing100043,China 2.Qian’an Iron and Steel Company of Shougang Group,Qian’an 064400,Hebei,China) Shougang Res Inst Technol Beijing 100043 Peoples R China Qianan Iron & Steel Co Shougang Grp Qianan 064400 Hebei Peoples R China

HTP practice,alloyed with low-carbon (less than 0.06%) and high-niobium (up to 0.11%),has been developed to produce large-wall X80 hot rolled strip for 2nd West-East Gas Pipeline project *** this paper,existing status of niobium at different rolling stage,such as reheating,rough rolling and final product and strengthening effects have been presented and analyzed *** technological questions concerrned,such as the mixed grain occurred on the delay table,dynamic recrystallization during the finish rolling course,γ→αtransformation and final microstructure obtained at low coiling temperature,have been explored *** results presented increased recrystallization stop temperature due to high niobium contents can provide the requisite to remove waiting-temperature operation of transfer bar before finish rolling to ensure controlled effect of traditional low-temperature,which is benificial not only to production efficiency,but also to uniformity of austenite ***,dynamic-recrystallization occurred during finish rolling may reduce the density of dislocation,but will better the grain gradient along the thickness because the dynamic recrystallization proceeds instantly,which is beneficial to reduce the appearance of separation of impact ***,the lower coiling temperature than traditional TMCP practice,up to 300℃,is a key factor to obtain low-carbon bainite microstructure composed of acicular ferrite and small amount M/A component,which results in high strength and excellent low-temperature toughness.

关键词： 2nd west-east gas pipeline project X80 hot rolled strip HTP high-niobium

Investigation of bubbles escape behavior from low basicity mold flux for high-Mn high-Al steels using 3D X-ray microscope

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International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 102-110页

作者： Qiang liu Xiang li Shen Du ming Gao Yanbin Yin Jiongming zhang State Key Laboratory of Advanced Metallurgy University of Science and Technology BeijingBeijing 100083China

During the continuous casting process of high-Mn high-Al steels,various types of gases such as Ar need to escape through the top of the *** which,the behavior of bubbles traversing the liquid slag serves as a restrictive link,closely associated with viscosity and the thickness of liquid *** contrast to two-dimensional surface observation,three-dimensional(3D)analysis method can offer a more intuitive,accurate,and comprehensive ***,this study employs a 3D X-ray microscope(3D-XRM)to obtained spatial distribution and 3D morphological characteristics of residual bubbles in mold flux under different basicity of liquid slag,different temperatures,and different holding *** results indicate that as basicity of slag increases from 0.52 to 1.03,temperature increases from 1423 to 1573 K,the viscosity of slag decreases,the floating rate of bubbles *** addition,when holding time increases from 10 to 30 s,the bubbles floating distance increases,and the volume fraction and average equivalent sphere diameter of the bubbles solidified in the mold flux gradually *** one word,increasing the basicity,temperature,and holding time leading to an increase in the removal rate of bubbles especially for the *** findings of bubbles escape behavior provide valuable insights into optimizing low basicity mold flux for high-Mn high-Al steels.

关键词： mold flux low basicity bubbles three-dimensional X-ray microscope viscosity

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高效率的三角网格模型保特征简化方法

光学精密工程 2017年第2期25卷 460-468页

作者：段黎明邵辉李中明张桂杨尚朋重庆大学光电技术及系统教育部重点实验室ICT研究中心重庆400044 重庆大学机械工程学院重庆400044

部分三角网格模型因数据量庞大而导致其不便于存储、分析和显示,本文提出了一种结合网格精细化方法的三角形折叠网格简化算法以解决此问题。首先通过3^(1/2)网格细分法确定待折叠三角形三个顶点的修正坐标,并根据修正坐标初步确定折叠... 详细信息

部分三角网格模型因数据量庞大而导致其不便于存储、分析和显示,本文提出了一种结合网格精细化方法的三角形折叠网格简化算法以解决此问题。首先通过3^(1/2)网格细分法确定待折叠三角形三个顶点的修正坐标,并根据修正坐标初步确定折叠点位置,然后引入折叠点的拉普拉斯坐标和原三角形法向信息来更新折叠点位置,最后由三角形折叠后该区域的体积误差和被折叠三角形的平展度共同确定折叠代价,从而使网格优先从较为平坦和特征点较少的区域开始依次进行三角形折叠简化。对多个模型进行了实验测试和数据分析,结果表明该方法能够有效精简网格数据,与3个不同类型的简化方法相比,该方法的简化效率最高,而且能有效保持原网格模型的几何特征并控制简化三角形的质量。

关键词：网格简化三角形折叠拉普拉斯坐标 3(1/2)细分法