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International Journal of Ophthalmology(English edition) 2015年第1期8卷 201-203页

作者： Ming chen Christian Swinney mindy chen University of Hawaii School of Medicine A.T. Still School of Medicine

AIM: To compare the complication rate of femtosecond laser-assisted cataract surgery(FLACS) and traditional phacoemulsification for the first 18 mo of FLACS use at a private surgical center in ***: A retrospective chart review was conducted from January 2012 to June 2013. The first 273 consecutive eyes receiving FLACS and 553 eyes receiving traditional phacoemulsification were *** surgeries were performed at a single surgical center in Hawaii. The presence of intraoperative complications was used as the main outcome measure. Approval was obtained from the institutional review board of the University of ***: The overall complication rate for FLACS was 1.8%, while that of the traditional procedure was5.8%(P <0.05). A majority of the surgeons(80%) had a lower complication rate while using ***: FLACS is comparable in safety, if not safer, than traditional cataract surgery when performed by qualified cataract surgeons on carefully selected patients.

关键词： femtosecond laser cataract surgery cataract surgery complications phacoemulsification

The <i>in Vivo</i>Antioxidant Effects of (−)-Epigallocatechin-3-Gallate Consumption in Healthy Postmenopausal Women Measured by Urinary Excretion of Secondary Lipid Peroxidation Products

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Food and Nutrition Sciences 2019年第1期10卷 15-27页

作者： Chelsey Fiecke mindy Kurzer Chi chen A.Saari Csallany Department of Food Science and Nutrition University of MinnesotaSt.PaulMNUSA

The present study was carried out to determine whether the consumption of epigallocatechin (EGCG), the major bioactive green tea catechin, exerts a positive effect on lowering in vivo lipid peroxidation, a measure of oxidative stress, in healthy postmenopausal women. Urinary excretion of secondary lipid peroxidation products, a measure of in vivo lipid peroxidation, was determined in 40 participants randomly assigned to consume a green tea catechin extract (843.0 ± 44.0 mg EGCG/d) or placebo capsules for 12 months. Urine samples were analyzed for individual polar and nonpolar lipophilic aldehydes and related carbonyl compounds by high-performance liquid chromatography (HPLC) at the beginning and at the end of the 12-month intervention period. Results show that two nonpolar aldehydes, nonanal and decatrienal, were both 48% lower (p in vivo antioxidant activity exists with long-term EGCG consumption, which could slightly limit oxidative damage associated with lipid peroxidation and the onset and progression of chronic diseases.

关键词： Antioxidants Epigallocatechin-3-Gallate Green Tea Humans Lipid Peroxidation Urinary Excretion

The terpene synthase(TPS)gene family in kiwifruit shows high functional redundancy and a subset of TPS likely fulfil overlapping functions in fruit flavour,floral bouquet and defence

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Molecular Horticulture 2023年第1期3卷 258-279页

作者： Wu Wang mindy Y.Wang Yunliu Zeng Xiuyin chen Xiaoyao Wang Anne M.Barrington Jianmin Tao Ross G.Atkinson Niels J.Nieuwenhuizen The New Zealand Institute for Plant and Food Research Ltd(PFR) Private Bag 92169AucklandNew Zealand Institute of Botany Jiangsu Province and Chinese Academy of SciencesNanjing 210014China Key Laboratory of Horticultural Plant Biology College of Horticulture and Forestry ScienceHuazhong Agricultural UniversityWuhan 430070People’s Republic of China College of Horticulture Nanjing Agricultural UniversityNanjing 210095China

Volatile terpenes are important compounds that influence fruit flavour and aroma of *** in plants also impact on the floral bouquet and defence against pests and pathogens in leaves and *** better understand the overlapping roles that terpenes may fulfil in plants,a systematic gene,chemical and biochemical analysis of terpenes and terpene synthases(TPS)was undertaken in Red5 kiwifruit(Actinidia spp.).Analysis of the Red5 genome shows it contains only 22 TPS gene models,of which fifteen encode full-length *** TPS can account for the major terpene volatiles produced in different tissues of Red5 kiwifruit and in response to different *** small Red5 TPS family displays surprisingly high functional redundancy with five TPS producing linalool/*** of leaves and fruit with methyl jasmonate enhanced expression of a subset of defence-related TPS genes and stimulated the release of *** TPS genes were induced upon herbivory of leaves by the economically important insect pest Ctenopseustis obliquana(brown-headed leaf roller)and emission,but not accumulation,of(E)-and(Z)-nerolidol was strongly linked to *** results provide a framework to understand the overlapping biological and ecological roles of terpenes in Actinidia and other horticultural crops.

关键词： Actinidia Aroma Genome analysis Monoterpene Sesquiterpene Volatile

A Diet with 3% of Energy from a Mixture of Omega-3 Fatty Acids Significantly Increases in Vivo Lipid Peroxidation in Postmenopausal Women

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Food and Nutrition Sciences 2016年第12期7卷 1099-1111页

作者： A. Saari Csallany Cheryl E. Ainslie-Waldman Lindsay R. Young Chi chen mindy S. Kurzer Susan K. Raatz Department of Food Science and Nutrition University of Minnesota Saint Paul MN USA Division of Epidemiology and Community Health University of Minnesota Minneapolis MN USA USDA Grand Forks Human Nutrition Center Grand Forks ND USA

Dietary omega-3 (n - 3) polyunsaturated fatty acids (PUFA) are recommended by public health organizations to reduce the risk of cardiovascular disease, and several epidemiological studies have suggested there is an inverse association between n - 3 intake and human cancers. However, n - 3 are susceptible to an increase in lipid peroxidation in the human body. As part of a crossover dietary intervention study of a diet (20% of energy from fat) with or without an additional 3% of energy from a mixture of n - 3 (with 5.36 g α-linolenic acid and 1.45 g eicosapentaenoic acid and docosahexaenoic acid per 2000 kcal per day), we measured total in vivo lipid peroxidation in healthy postmenopausal women (n = 15). Our results indicated that the diet with 3% of energy from n - 3 significantly increased the urinary concentrations of total polar lipophilic aldehydes and related compounds produced via lipid peroxidation (p α, β-unsaturated hydroxy aldehydes 4-hydroxy-2-trans - hexenal (p trans -decenal (p < 0.05) compared to the diet with less than 1% of energy from n - 3. This is also the first study to document the presence of 4-hydroxy-2-trans -decenal in the urine of individuals consuming n - 3. These results demonstrate that an increase in 3% of energy from dietary n – 3 increases in vivo lipid peroxidation.

关键词： Lipid Peroxidation n – 3 Fatty Acids Human HHE 4-Hydroxyhexenal HDE 4-Hydroxydecenal α β-4-Hydroxyaldehydes HPLC MS