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Occupational physical activity, all-cause, cardiovascular disease, and cancer mortality in 349,248 adults: Prospective and longitudinal analyses of the MJ Cohort

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Journal of Sport and Health Science 2024年第4期13卷 579-589页

作者： Emmanuel Stamatakis Matthew N.Ahmadi Tiana-Lee Elphick Bo-Huei Huang Susan Paudel Armando Teixeira-Pinto Li-jung Chen Borja del Pozo Cruz Yun-Ju Lai Andreas Holtermann Po-Wen Ku Sydney School of Health Sciences Faculty of Medicine and HealthCharles Perkins CentreUniversity of SydneySydneyNSW 2006Australia Sydney School of Public Health Faculty of Medicine and HealthUniversity of SydneySydneyNSW 2006Australia Department of Exercise Health Science “National”Taiwan University of SportTaichung 40404China Department of Sports Science and Clinical Biomechanics University of Southern DenmarkOdense 5230Denmark Division of Endocrinology and Metabolism Department of Internal MedicinePuli Branch of Taichung Veterans General HospitalNantou 54552China National Research Centre for the Working Environment Copenhagen 2100Denmark Graduate Institute of Sports and Health Management “National”Chung Hsing UniversityTaichung 40227China

Background:Evidence on the health benefits of occupational physical activity(OPA)is *** examined the associations of baseline OPA and OPA changes with all-cause,cardiovascular disease(CVD),and cancer mortality and survival ***:This study included prospective and longitudinal data from the MJ Cohort,comprising adults over 18 years recruited in 1998-2016,349,248 adults(177,314 women)with baseline OPA,of whom 105,715(52,503 women)had 2 OPA measures at 6.3±4.2 years(mean±SD)*** were baseline OPA,OPA changes,and baseline leisure-time physical ***:Over a mean mortality follow-up of 16.2±5.5 years for men and 16.4±5.4 years for women,11,696 deaths(2033 of CVD and 4631 of cancer causes)in men and 8980 deaths(1475 of CVD and 3689 of cancer causes)in women *** moderately heavy/heavy baseline OPA was beneficially associated with all-cause mortality in men(multivariable-adjusted hazard ratio(HR)=0.93,95%confidence interval(95%CI):0.89-0.98 compared to light OPA)and women(HR=0.86,95%CI:0.79-0.93).Over a mean mortality follow-up of 12.5±4.6 years for men and 12.6±4.6 years for women,OPA decreases in men were detrimentally associated(HR=1.16,95%CI:1.01-1.33)with all-cause mortality,while OPA increases in women were beneficially(HR=0.83,95%CI:0.70-0.97)associated with the same *** or changes in OPA showed no associations with CVD or cancer ***:Higher baseline OPA was beneficially associated with all-cause mortality risk in both men and *** longitudinal OPA analyses partly confirmed the prospective findings,with some discordance between sex groups.

关键词： Cancer Cardiovascular disease Epidemiology Mortality

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SMARCA4-deficient undifferentiated thoracic tumor:A case report

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World Journal of Clinical Cases 2023年第11期11卷 2521-2527页

作者： Hee jung Kwon min Hye Jang Department of Pathology Yeungnam University Medical CenterDaegu 42415South Korea

BACKGROUND SMARCA4-deficient undifferentiated tumors(SMARCA4-DUTs)present with diverse clinical manifestations and progress to metastasis and even cause death within a few *** novel subset of undifferentiated tumors occurs in the middle-aged population and is strongly associated with a smoking ***-guishing it from other malignancies is *** SUMMARY A 62-year-old man presented with chest pain for 7 *** patient had no respiratory symptoms and normal pulmonary function test *** patient had been a smoker for 8 years and quit smoking 2 years *** computed tomography revealed a huge mass involving the left upper and lower lung lobes with pericardial invasion and multiple *** samples were obtained using open frozen biopsy,after several unsuccessful *** tumor was composed of sheets of undifferentiated disclosive cells with vesicular nuclei and prominent *** differential diagnosis included high-grade lymphoma,germ cell tumor,NUT carcinoma,undifferentiated carcinoma,and *** tumor cells were large,arranged in sheets,and did not exhibit glandular or squamous *** foci of necrosis were *** was no evidence of epithelial differentiation on immunohistochemical *** SMARCA4 stain showed complete loss of expression of SMARCA4,which is *** In the present case,thoracic SMARCA4-DUT was diagnosed based on clinical features,absence of epithelial differentiation,and negative SMARCA4 expression.

关键词： SMARCA4 BRG1 Deficient Undifferentiated tumor Thoracic Case report

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Large retroperitoneal atypical spindle cell lipomatous tumor,an extremely rare neoplasm:A case report

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World Journal of Clinical Cases 2022年第8期10卷 2584-2590页

作者： jung-min Bae Chang-Yeon jung Woo-Sung Yun Joon Hyuk Choi Department of Surgery Yeungnam University College of MedicineDaegu 42415South Korea Kyungpook National University School of Medicine Jung-guDaegu 41944Korea Department of Pathology Yeungnam University College of Medicine Nam-guDaegu 42415Korea

BACKGROUND Atypical spindle cell lipomatous tumor(ASLT)is a rare soft tissue neoplasm with a low potential for *** frequently occurs in the limb and limb ***,large retroperitoneal ASLTs are extremely *** was no concrete case report of retroperitoneal *** SUMMARY An 18-year-old woman presented with abdominal pain and a palpable *** computed tomography revealed a large fatty mass that was approximately 30 cm in size and filled the entire abdominal *** excision was *** tumor did not invade the adjacent *** pelvic cavity was then too narrow to dissect *** mass was successfully excised without tumor rupture or adjacent organ ***,the neoplasm was a well-differentiated adipocytic *** staining showed that the spindle cells were positive for CD34 and desmin,in addition to multifocal positivity for S100 *** histological features were consistent with an *** patient’s postoperative course was *** the 12-mo followup,no evidence of recurrence or metastasis was *** To the best of our knowledge,our study is the first concrete report of a large retroperitoneal ASLT in the English *** the large retroperitoneal ASLT located in the pelvic cavity,which made it too narrow and tight to dissect,complete excision is difficult but very important because of recurrence *** large retroperitoneal ASLTs are considered extremely rare,their detection is important for accurate evaluation and *** to their significant rarity,retrospective multicenter case studies are required to determine the clinicopathologic characteristics.

关键词： Neoplasms Retroperitoneal space Spindle cell Case report

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Acute kidney injury due to intravenous detergent poisoning:A case report

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World Journal of Clinical Cases 2022年第6期10卷 2036-2044页

作者： Sungbin Park Hyun-sik Ryu Jae-Kwang Lee Sung-Soo Park Sun-jung Kwon Won-min Hwang Sung-Ro Yun Moon-Hyang Park Yohan Park Department of Internal Medicine Division of NephrologyKonyang University HospitalCollege of MedicineDaejeon 35365South Korea Department of Emergency Medicine Konyang University HospitalCollege of MedicineDaejeon 35365South Korea Department of Internal Medicine Division of Respiratory and Critical Care MedicineKonyang University HospitalCollege of MedicineDaejeon 35365South Korea Department of Pathology Konyang University HospitalCollege of MedicineDaejeon 35365South Korea

BACKGROUND Detergent poisoning mostly occurs through oral ingestion(>85%),ocular exposure(<15%),or dermal exposure(<8%).Reports of detergent poisoning through an intravenous injection are extremely *** addition,there are very few cases of renal toxicity directly caused by ***,we report a unique case of acute kidney injury caused by detergent poisoning through an accidental intravenous *** SUMMARY A 61-year-old man was intravenously injected with 20 mL of detergent by another patient in the same room of a local *** surfactant and calcium carbonate accounted for the largest proportion of the *** patient complained of vascular pain,chest discomfort,and nausea,and was transferred to our *** hospitalization,the patient’s serum creatinine level increased to 5.42 mg/dL,and his daily urine output decreased to approximately 300 *** biopsy findings noted that the glomeruli were relatively intact;however,diffuse acute tubular injury was *** edema was also noted,and the patient underwent a total of four hemodiafiltration ***,the patient’s urine output gradually increased whereas the serum creatinine level *** patient was discharged in a stable status without any *** Detergents appear to directly cause renal tubular injury by systemic *** treating a patient with detergent poisoning,physicians should be aware that the renal function may also *** addition,timely renal replacement therapy may help improve the patient’s prognosis.

关键词： Detergents Poisoning Intravenous injection Acute kidney injury Acute tubular injury Case report

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Uncontrolled high blood pressure under total intravenous anesthesia with propofol and remifentanil:A case report

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World Journal of Clinical Cases 2022年第26期10卷 9411-9416页

作者： min jung Jang Jee Hee Kim Hae Jeong Jeong Anesthesiology and Pain Medicine National Cancer CenterGoyang 10408South Korea

BACKGROUND Although propofol generally reduces blood pressure,rarely,it causes ***,the mechanism by which propofol increases blood pressure has not been established,and so far,there are only a few reported *** SUMMARY A 46-year-old woman,diagnosed with thyroid cancer,was administered general anesthesia with propofol and remifentanil for a thyroid *** increase in the concentrations of intravenous anesthetics further increased her blood *** blood pressure remained stable when anesthesia was maintained with sevoflurane and remifentanil after the interruption of propofol *** We concluded that propofol administration was the cause of increased blood pressure.

关键词： Anesthesia Intravenous Hypertension Propofol Remifentanil Tachycardia Case report

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以健侧为镜像治疗单侧冠状缝早闭症疗效分析

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临床小儿外科杂志 2024年第2期23卷 130-134页

作者：吴水华梁大中中南大学湘雅医学院附属儿童医院湖南省儿童医院神经外科长沙410007 韩国世翰大学研究生院物理治疗系韩国全罗南道木浦58447

目的探讨婴幼儿单侧冠状缝早闭症的临床特点及手术治疗方法。方法回顾性分析湖南省儿童医院神经外科2019年3月至2023年3月收治的27例单侧冠状缝早闭症患儿临床资料。患儿年龄均大于3个月,头颅外观均呈不同程度前斜头畸形,均经头面部CT... 详细信息

目的探讨婴幼儿单侧冠状缝早闭症的临床特点及手术治疗方法。方法回顾性分析湖南省儿童医院神经外科2019年3月至2023年3月收治的27例单侧冠状缝早闭症患儿临床资料。患儿年龄均大于3个月,头颅外观均呈不同程度前斜头畸形,均经头面部CT平扫加三维重建明确诊断,行3D打印设计骨瓣,根据颅骨畸形特点、畸形程度及就诊年龄制定手术方案。手术均以健侧为镜像行患侧眼眶重塑整形、以成形眶骨瓣为基线与额骨瓣契合成为"新额部"。观察患儿前斜头畸形改善情况以及颅腔容积变化。结果27例单侧冠状缝早闭症患儿术后平均随访2.4年(3个月至4年),双侧前额与双侧眼眶均位于同一冠状面,前斜头畸形与患侧额叶发育均较术前明显改善,无一例再次手术病例。结论对于大于3月龄的单侧冠状缝早闭患儿,采取以健侧为镜像重塑患侧眼眶,以成形眶骨瓣为基线重塑额骨瓣形成"新额头"的颅骨重塑整形手术,可获得满意疗效。

关键词：颅缝早闭冠状缝早闭外科手术治疗结果儿童

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人机工程学在现代茶具设计中的实践与思考

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福建茶叶 2024年第3期46卷 81-83页

作者：谢潇扬 jung SUNGWOOK 浙江农林大学艺术设计学院浙江杭州311300

本文探讨了人机工程学在现代茶具设计中的实践与思考,通过深入研究茶具工艺和传统工艺的发展,文章强调了在设计中融入工艺美学的重要性。实证研究展示了基于人机工程学的现代茶具设计案例,平衡了工艺之美与实用性。总结中强调了人机工... 详细信息

本文探讨了人机工程学在现代茶具设计中的实践与思考,通过深入研究茶具工艺和传统工艺的发展,文章强调了在设计中融入工艺美学的重要性。实证研究展示了基于人机工程学的现代茶具设计案例,平衡了工艺之美与实用性。总结中强调了人机工程学在传统工艺与现代审美之间的关键作用,为茶具设计提供了理论支持。

关键词：人机工程学现代茶具设计传统工艺

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Acute liver injury induces expression of FGF23 in hepatocytes via orphan nuclear receptor ERRγ signaling

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Genes & Diseases 2023年第3期10卷 679-682页

作者： Yoon Seok jung Yong-Hoon Kim Kamalakannan Radhakrishnan jung-Ran Noh jung Hyeon Choi Hyo-Jin Kim Jae-Ho Jeong Steven Dooley Chul-Ho Lee Hueng-sik Choi School of Biological Sciences and Technology Chonnam National UniversityGwangju 61186Republic of Korea Laboratory Animal Resource Center Korea Research Institute of Bioscience and Biotechnology125 Gwahak-roYuseong-guDaejeon 34141Republic of Korea Department of Functional Genomics KRIBB School of BioscienceKorea University of Science and Technology(UST)Daejeon 34113Republic of Korea Combinatorial Tumor Immunotherapy MRC Chonnam National University Medical SchoolHwasun-gunJeonnam 58128Republic of Korea Department of Microbiology Chonnam National University Medical SchoolGwangju 61186Republic of Korea Molecular Hepatology Section Medical Faculty MannheimHeidelberg University69117 HeidelbergGermany

Fibroblast growth factor 23(FGF23)is an osteocyte-and osteoblast-derived hormone that primarily regulates phosphate and vitamin D *** FGF23 levels are abnormally increased in pathological conditions like acute or chronic kidney injury,resulting in disease progression as well as increased rates of morbidity and mortality.^(1) However,FGF23 production in acute liver injury is not fully *** this study.

关键词： FGF23 acute vitamin

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Reaction to the COVID-19 pandemic in Seoul with biostatistics

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Infectious Disease Modelling 2022年第3期7卷 419-429页

作者： Seungpil jung Seung-sik Hwang Kyoung-Nam Kim Woojoo Lee Department of Public Health Sciences Graduate School of Public HealthSeoul National University08826Republic of Korea Department of Preventive Medicine and Public Health Ajou University School of MedicineSuwon16499Republic of Korea

This paper discusses our collaboration work with government officers in the health department of Seoul during the COVID-19 ***,we focus on short-term forecasting for the number of new confirmed cases and severe ***,we focus on understanding how much of the current infections has been affected by external influx from neighborhood areas or internal transmission within the *** understanding may be important because it is linked to the government policy determining nonpharmaceutical *** obtain the decomposition of the effect,districts of Seoul should be considered simultaneously,and multivariate time series models are ***,we focus on predicting the number of new weekly confirmed cases for each district in *** detailed prediction may be important to the government policy on resource *** consider an ensemble method to overcome poor prediction performance of simple *** paper presents the methodological details and analysis results of the study.

关键词： Count time series model COVID-19 Endemic-epidemic model

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Understanding intrarenal backflow: Intrarenal pressure during ureteroscopy and beyond

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Asian Journal of Urology 2024年第2期11卷 139-142页

作者： Palle J.S.Osther Susanne S.Osther Maria P.Hesselholt Sofia Byllov Søren K.Lildal Louise F.Øbro Helene jung Urological Research Center Department of UrologyVejle Hospital(a part of Lillebaelt Hospital)University Hospital of Southern DenmarkVejleDenmark Department of Regional Health Research University of Southern DenmarkOdenseDenmark

The number of ureterorenoscopic procedures for upper urinary tract stone management has increased dramatically during recent years worldwide[1].Developments in flexible ureteroscope and laser technology have made it possible to successfully address larger and more complex stone scenarios *** the other hand,this means that more and more patients are exposed to the potential adverse effects of ureteroscopy[2].In general,ureteroscopy is considered a safe ***,serious complications and even deaths do occur,and these events are most likely underreported[3,4].

关键词： beyond likely ureter

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