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Electrostabilized homogeneous dispersion of boron nitride nanotubes in wide-range of solvents achieved by surface polarity modulation through pyridine attachment

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Nano Research 2020年第2期13卷 344-352页

作者： Mi Se Chang min-sun jang Sangsun Yang Jihun Yu Taehoon Kim Sedong Kim Hyomin Jeong Chong Rae Park Jae Won Jeong Powder/Ceramic Research Division Korea Institute of Materials Science797 Changwondae-roSeongsan.guChangwon 51508Republic of Korea Research Institute of Advanced Materials and Department of Materials Science and Engineering Seoul National University Seoul 08826Republic of Korea Composites Research Division Korea Institute of Materials Science797 Changwondae-roSeongsan-guChangwon 51508Republic of Korea Dept.of Energy and Mech.Eng Gyeongsang National UniversityCheondaegukchi-Gil 38Tongyeong 53064Republic of Korea

Boron nitride nanotubes(BNNTs)show exceptional physical properties including high mechanical strength and thermal conductivity;however,their applications have been restricted due to limited dispersibility in processing ***,a novel BNNT dispersion method with exceptional dispersibility in a wide range of solvents has been demonstrated by surtace polarity modulation through short-molecule pyridine *** atoms in pyridine are selectively bonded to electron-deficient boron atoms of the BNNT surface through Lewis acid-base reaction,which changes the surface polarity of BNNTs from neutral to ***-dispersing pyridine-attached BNNTs(Py-BNNTs)create a thick and stable electronic double layer(EDL),resulting in uniform dispersion of BNNTs in solvents with an exceptional solubility parameter range of 18.5-48 MPa^1/*** uniform dispersion of BNNTs is maintained even after the mixing with diverse ***,composites incorporating uniformly-distributed BNNTs have been realized,and extraordinary property enhancements have been *** thermal conductivity of 20 wt.%Py-BNNT/epoxy composite has been significantly improved by 69.6%and the tensile strength of 2 wt.%Py-BNNT/PVA has been dramatically improved by 75.3%.Our work demonstrates a simple and facile route to dispersing BNNTs in diverse solvents,consequently leading to selective utlization of BNNT dispersed solvents in various application fields.

关键词： boron nitride nanotube one-dimensional nanomaterials surface polarity modulation electrostabilization boron nitride nanotube composite

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Saccharomyces boulardii as a single trigger of food protein-induced enterocolitis syndrome: Seven case reports

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World Journal of Clinical Cases 2025年第6期13卷 35-40页

作者： Jin-Bok Hwang Hyo-Jeong jang Department of Pediatrics Keimyung University School of MedicineDongsan Medical CenterDaegu 42601South Korea

BACKGROUND Food protein-induced enterocolitis syndrome(FPIES)is the most serious type of non-immunoglobulin E(IgE)-mediated food allergic reaction manifesting as sepsis-like symptom,which can lead to *** boulardii(***),a probiotic prescribed frequently in clinical settings,has been reported to trigger FPIES in an infant with soy-triggered *** this report,we describe a new clinical FPIES in which *** was the sole triggering factor of acute FPIES adverse reaction in seven healthy *** SUMMARY Seven FPIES cases triggered by only *** were gathered from 2011 to the *** of the patients had previously experienced any allergic reaction to cow’s milk,soy,or complementary *** age of the patients was 4-10-months old,and the symptoms of FPIES developed after ingestion of ***,which is mostly prescribed for the treatment of gastroenteritis or antibiotic-associated *** patients experienced severe repetitive vomiting 1-3 hours after *** *** lethargy,marked pallor,and cyanosis were also *** IgE-mediated hypersensitivity developed in any *** was followed by initial intense vomiting in approximately 5-10 hours after *** ingestion,and only one case showed bloody,purulent,and foul-smelling *** patients stabilized quickly,mostly within 6 *** got all improved within 24 hours after discontinuation of *** *** can be the sole trigger of acute FPIES and be prescribed cautiously even in healthy children without FPIES.

关键词： Food protein-induced enterocolitis syndrome Food hypersensitivity Saccharomyces boulardii Probiotics Child Case report

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Regulation of sleep by astrocytes in the hypothalamic ventrolateral preoptic nucleus

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Neural Regeneration Research 2025年第4期20卷 1098-1100页

作者： Jae-Hong Kim Ruqayya Afridi Il-sung jang Maan Gee Lee Kyoungho Suk Brain Korea 21 four KNU Convergence Educational Program of Biomedical Sciences for Creative Future Talents School of MedicineKyungpook National UniversityDaeguRepublic of Korea Department of Pharmacology School of MedicineKyungpook National UniversityDaeguRepublic of Korea Department of Pharmacology School of DentistryKyungpook National UniversityDaeguRepublic of Korea Brain Science&Engineering Institute Kyungpook National UniversityDaeguRepublic of Korea

Astrocytes are functionally dynamic cells that support neurons in multiple ways throughout an organism’s *** astrocytic regulation of neuronal activity has been increasingly recognized in recent *** are now recognized as playing a more complex role than mere bystanders in the central nervous ***,their role in regulating the sleep neurocircuitry is not well *** this perspective,we highlight the role of astrocytes in sleep modulation,with a particular focus on regulatory mechanisms related to the ventrolateral preoptic nucleus(VLPO)of the *** briefly discuss recent literature reporting the role of VLPO astrocytes in regulating sleep-associated behaviors.

关键词： sleep ventrolateral astrocytes

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Towards high-performance and robust anion exchange membranes(AEMs)for water electrolysis:Super-acid-catalyzed synthesis of AEMs

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Journal of Energy Chemistry 2024年第6期93卷 478-510,I0012页

作者： Geun Woong Ryoo sun Hwa Park Ki Chang Kwon Jong Hun Kang Ho Won jang min Sang Kwon Department of Materials Science and Engineering Research Institute of Advanced Materials(RIAM)Seoul National UniversitySeoul 08826Republic of Korea Interdisciplinary Materials Measurement Institute Korea Research Institute of Standards and Science(KRISS)Daejeon 34113Republic of Korea Department of Chemical and Biological Engineering and Institute of Chemical ProcessSeoul National UniversitySeoul 08826Republic of Korea Department of Applied Measurement Science University of Science and TechnologyDaejeon 34113Republic of Korea

The increasing demand for hydrogen energy to address environmental issues and achieve carbon neutrality has elevated interest in green hydrogen production,which does not rely on fossil *** various hydrogen production technologies,anion exchange membrane water electrolyzer(AEMWE)has emerged as a next-generation technology known for its high hydrogen production efficiency and its ability to use non-metal ***,this technology faces significant challenges,particularly in terms of the membrane durability and low ionic *** address these challenges,research efforts have focused on developing membranes with a new backbone structure and anion exchange groups to enhance durability and ionic ***,the super-acid-catalyzed condensation(SACC)synthesis method stands out due to its user convenience,the ability to create high molecular weight(MW)polymers,and the use of oxygen-tolerant organic *** the synthesis of anion exchange membranes(AEMs)using the SACC method began in 2015,and despite growing interest in this synthesis approach,there remains a scarcity of review papers focusing on AEMs synthesized using the SACC *** review covers the basics of SACC synthesis,presents various polymers synthesized using this method,and summarizes the development of these polymers,particularly their building blocks including aryl,ketone,and anion exchange *** systematically describe the effects of changes in the molecular structure of each polymer component,conducted by various research groups,on the mechanical properties,conductivity,and operational stability of the *** review will provide insights into the development of AEMs with superior performance and operational stability suitable for water electrolysis applications.

关键词： Green hydrogen production Water electrolysis Anion exchange membrane water electrolyzer(AEMWE) Anion exchange membranes(AEMs) Super-acid-catalyzed condensation(SACC)

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Oral administration of red ginseng powder fermented with probiotic alleviates the severity of dextran-sulfate sodium-induced colitis in a mouse model

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Chinese Journal of Natural Medicines 2017年第3期15卷 192-201页

作者： jang sun-Hee PARK Jisang KIM Sae-Hae CHOI Kyung-min KO Eun-Sil CHA Jeong-Dan LEE Young-Ran jang Hyonseok jang Yong-Suk Department of Molecular Biology and Institute for Molecular Biology and Genetics Chonbuk National UniversityJeonju 54896Korea Department of Bioactive Material Sciences and Research Center of Bioactive Materials Chonbuk National UniversityJeonju 54896Korea Department of Efficacy Research Institute of Jinan Red GinsengJinan 55442Korea Department of Mathematics Sogang UniversitySeoul 04107Korea Department of Oral Maxillofacial Surgery Korea University Ansan HospitalAnsan 15355Korea

Red ginseng is a well-known alternative medicine with anti-inflammatory *** exerts pharmacological effects through the transformation of saponin into metabolites by intestinal *** that intestinal microflora vary among individuals,the pharmacological effects of red ginseng likely vary among *** order to produce homogeneously effective red ginseng,we prepared probiotic-fermented red ginseng and evaluated its activity using a dextran sulfate sodium(DSS)-induced colitis model in *** analysis of intestinal damage indicated that the administration of probiotic-fermented red ginseng significantly decreased the severity of colitis,compared with the control and the activity was higher than that induced by oral administration of ginseng powder or probiotics *** analysis of the levels of serum IL-6 and TNF-α,inflammatory biomarkers that are increased at the initiation stage of colitis,were significantly decreased in probiotic-fermented red ginseng-treated groups in comparison to the control *** levels of inflammatory cytokines and mR NAs for inflammatory factors in colorectal tissues were also significantly decreased in probiotic-fermented red ginseng-treated ***,oral administration of probiotic-fermented red ginseng reduced the severity of colitis in a mouse model,suggesting that it can be used as a uniformly effective red ginseng product.

关键词： Colitis Fermentation Inflammation Probiotics Red ginseng

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Motor outcomes of patients with a complete middle cerebral artery territory infarct

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Neural Regeneration Research 2013年第20期8卷 1892-1897页

作者： sung Ho jang min Cheol Chang Department of Physical Medicine and Rehabilitation College of MedicineYeungnam UniversityDaegu 705-717Republic of Korea

Detailed knowledge of motor outcomes enables to establish proper goals and rehabilitation strate-gies for stroke patients. Several previous studies have reported functional or motor outcomes in patients with a middle cerebral artery territory infarct. However, little is known about motor outcome in patients with a complete middle cerebral artery territory infarct. In this study, we investigated the motor outcomes in 23 patients with a complete middle cerebral artery territory infarct. All of these patients received comprehensive rehabilitative management, including movement therapy and neuromuscular electrical stimulation of the affected finger extensors and ankle dorsiflexors, for more than 3 months. Motor outcomes were measured at 6 months after stroke onset using the Medical Research Council, Motricity Index, the modified Brunnstrom Classification, and Functional Ambula-tion Category scores. The motor function of the lower extremities was found to be better than that of the upper extremities. After receiving rehabilitation treatments for 3–6 months, about 70% of these patients were able to walk independently （Functional Ambulation Category scores 3）, but no pa-tient achieved functional hand recovery.

关键词： neural regeneration brain injury cerebral infarct motor function stroke middle cerebral artery hand function walking ability grants-supported paper neuroregeneration

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Long-lasting,reinforced electrical networking in a high-loading Li_(2)S cathode for high-performance lithium–sulfur batteries

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Carbon Energy 2023年第8期5卷 1-14页

作者： Hun Kim Kyeong-Jun min Sangin Bang jang-Yeon Hwang Jung Ho Kim Chong SYoon Yang-Kook sun Department of Energy Engineering Hanyang UniversitySeoulRepublic of Korea Department of Materials Science and Engineering Chonnam National UniversityGwangjuRepublic of Korea Institute for Superconducting&Electronic Materials(ISEM) Australian Institute of Innovative Materials(AIIM)University of WollongongNew South WalesNorth WollongongAustralia Department of Materials Science and Engineering Hanyang UniversitySeoulRepublic of Korea

Realizing a lithium sulfide(Li_(2)S)cathode with both high energy density and a long lifespan requires an innovative cathode design that maximizes electrochemical performance and resists electrode ***,a high-loading Li_(2)S-based cathode with micrometric Li_(2)S particles composed of two-dimensional graphene(Gr)and one-dimensional carbon nanotubes(CNTs)in a compact geometry is developed,and the role of CNTs in stable cycling of high-capacity Li–S batteries is *** a dimensionally combined carbon matrix,CNTs embedded within the Gr sheets create robust and sustainable electron diffusion pathways while suppressing the passivation of the active carbon *** a unique point,during the first charging process,the proposed cathode is fully activated through the direct conversion of Li_(2)S into S_(8) without inducing lithium polysulfide *** direct conversion of Li_(2)S into S_(8) in the composite cathode is ubiquitously investigated using the combined study of in situ Raman spectroscopy,in situ optical microscopy,and cryogenic transmission electron *** composite cathode demonstrates unprecedented electrochemical properties even with a high Li_(2)S loading of 10 mg cm^(–2);in particular,the practical and safe Li–S full cell coupled with a graphite anode shows ultra-long-term cycling stability over 800 cycles.

关键词： carbon nanotubes electrical network high energy high loading Li_(2)S cathode lithium-sulfur batteries

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Delayed activation of leg somatotopic fibers of an injured corticospinal tract in a patient with cerebral infarction

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Neural Regeneration Research 2022年第11期17卷 2551-2552页

作者： min Jye Cho sung Ho jang Department of Physical Medicine and Rehabilitation College of MedicineYeungnam UniversityNamkuDaeguRepublic of Korea

Stroke is a leading cause of major adult disabilities,and motor weakness is one of the most serious disability-related sequelae of *** of the motor recovery in stroke patients is reported to occur within 6months after stroke onset,and this period is deemed critical for motor recovery in stroke(Grefkes and Fink,2020;Olafson et al.,2021).

关键词： cerebral infarction

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Modified embedded-atom method interatomic potentials for Mg-Al-Ca and Mg-Al-Zn ternary systems

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Journal of Magnesium and Alloys 2021年第1期9卷 317-335页

作者： Hyo-sun jang Donghyuk Seol Byeong-Joo Lee Department of Materials Science and Engineering Pohang University of Science and Technology(POSTECH)Pohang 37673Republic of Korea

Al,Ca,and Zn are representative commercial alloying elements for Mg *** investigate the effects of these elements on the deformation and recrystallization behaviors of Mg alloys,we develop interatomic potentials for the Al-Ca,Al-Zn,Mg-Al-Ca and Mg-Al-Zn systems based on the second nearest-neighbor modified embedded-atom method *** developed potentials describe structural,elastic,and thermodynamic properties of compounds and solutions of associated alloy systems in reasonable agreement with experimental data and higher-level *** applicability of these potentials to the present investigation is confirmed by calculating the generalized stacking fault energy for various slip systems and the segregation energy on twin boundaries of the Mg-Al-Ca and Mg-Al-Zn alloys,accompanied with the thermal expansion coefficient and crystal structure maintenance of stable compounds in those alloys.

关键词： 2NN MEAM Interatomic potential Mg-Al-Ca Mg-Al-Zn Atomistic simulation

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Recent advances in electronic devices for monitoring and modulation of brain

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Nano Research 2021年第9期14卷 3070-3095页

作者： Yong Won Kwon Yoon sun Jun Young-Geun Park Jiuk jang jang-Ung Park Nano Science Technology Institute Department of Materials Science and EngineeringYonsei UniversitySeoul 03722Republic of Korea Center for Nanomedicine Institute for Basic Science(IBS)Seoul 03722Republic of Korea Graduate Program of Nano Biomedical Engineering(NanoBME) Advanced Science InstituteYonsei UniversitySeoul 03722Republic of Korea

The brain is actuated by billions of neurons with trillions of interconnections that regulate human *** the mechanisms of these systems that induce sensory reactions and respond to disease remains one of the greatest challenges in science,engineering,and *** advances in nanomaterials and nanotechnologies have led to the extensive research of electronic devices for brain interfaces to better understand the neural activities of the brains complex nervous *** development of sensor devices for monitoring the physiological signals of the brain related to traumatic injury status has accompanied by the progress of electronic neural probes in *** addition,these neurological and stereotactic surgical revolutions hold immense potential for clinical analysis of pharmacological systems within cerebral ***,we review the progress of electronic devices interfacing with brain in terms of the materials,fabrication technologies,and device *** activity can be measured and modulated by brain probes based on newly developed nanofabrication ***,in vivo pathological monitoring of the brain and pharmacological assessment has been developed in miniaturized and wireless *** also consider the key challenges and prospects for further development,and explore the future directions emerging in the latest research.

关键词： neural interfaces neural recording neuromodulation intracranial pressure monitoring microfluidic drug delivery

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