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Risk of complications and urinary incontinence following cytoreductive prostatectomy： a multi-institutional study

Asian Journal of Andrology 2018年第1期20卷 9-14页

作者： Dae Keun Kim Jaspreet Singh Parihar Young Suk kwon Sinae Kim Brian Shinder Nara Lee Nicholas Farber Thomas Ahlering Douglas Skarecky Bertram Yuh Nora Ruel Wun-lae Kim Koon Ho Rha Isaac Yi Kim Department of Urology CHA Seoul Station Medical Center CHA University CHA Medical School Seou104637 Korea Department of Urology School of Medicine Graduate School Hanyang University Seou104763 Korea Section of Urologic Oncology Rutgers Cancer Institute of New Jersey and Division of Urology Rutgers Robert Wood Johnson Medical School Rutgers The State University of New Jersey New Brunswick 08901 USA Department of Biostatistics Rutgers School of Public Health The State University of New Jersey New Brunswick NJ Piscataway 08854 USA Department of Internal Medicine Rutgers Robert Wood Johnson Medical School Rutgers The State University of New Jersey New Brunswick 08901 USA Department of Urology University of California Irvine School of Medicine Orange 92687 USA Division of Urology and UroLogic Oncology City of Hope National Medical Center Duarte 91010 USA Department of Urology Chungbuk National University College of Medicine Cheongju 28644 Korea Department of Urology and Urological Science Institute College of Medicine Yonsei University Seou103722. Korea

Emerging evidence has suggested that cytoreductive prostatectomy （CRP） allows superior oncologic control when compared to current standard of care androgen deprivation therapy alone. However, the safety and benefit of cytoreduction in metastatic prostate cancer （mPCa） has not been proven. Therefore, we evaluated the incidence of complications following CRP in men newly diagnosed with mPCa. A total of 68 patients who underwent CRP from 2006 to 2014 at four tertiary surgical centers were compared to 598 men who underwent radical prostatectomy for clinically localized prostate cancer （PCa）. Urinary incontinence was defined as the use of any pad. CRP had longer operative times （200 min vs 140 min, P 〈 0.0001） and higher estimated blood loss （250 ml vs 125 ml, P 〈 0.0001） compared to the control group. However, both overall （8.82% vs 5.85%） and major complication rates （4.41% vs 2.17%） were comparable between the two groups. Importantly, urinary incontinence rate at 1-year after surgery was significantly higher in the CRP group （57.4% vs 90.8%, P 〈 0.0001）. Univariate logistic analysis showed that the estimated blood loss was the only independent predictor of perioperative complications both in the unadjusted model （OR： 1.18; 95% Ch 1.02-1.37; P= 0.025） and surgery type-adjusted model （OR： 1.17; 95% Ch 1.01-1.36; P= 0.034）. In conclusion, CRP is more challenging than radical prostatectomy and associated with a notably higher incidence of urinary incontinence. Nevertheless, CRP is a technically feasible and safe surgery for selecting PCa patients who present with node-positive or bony metastasis when performed by experienced surgeons. A prospective, multi-institutional clinical trial is currently underway to verify this concept.

关键词： cytoreductive surgical procedures metastatic prostate cancer outcome radical prostatectomy

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Bevacizumab plus infusional 5-fluorouracil,leucovorin and irinotecan for advanced colorectal cancer that progressed after oxaliplatin and irinotecan chemotherapy:A pilot study

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World Journal of Gastroenterology 2007年第46期13卷 6231-6235页

作者： Hyuk-Chan kwon Sung Yong Oh Suee Lee Sung-Hyun Kim Hyo-Jin Kim Departments of Internal Medicine Dong-A University College of MedicineBusan 602-715Korea

瞄准：与 infusional 评估 bevacizumab 的联合 5 氟尿嘧啶(5-FU ) ，甲酰四氢叶酸(LV ) 和在有先进颜色的病人的 irinotecan (FOLFIRI ) 有包括 irinotecan 和 oxaliplatin 的联合政体的表面的癌症(CRC ) pretreated。方法：十四个病人... 详细信息

瞄准：与 infusional 评估 bevacizumab 的联合 5 氟尿嘧啶(5-FU ) ，甲酰四氢叶酸(LV ) 和在有先进颜色的病人的 irinotecan (FOLFIRI ) 有包括 irinotecan 和 oxaliplatin 的联合政体的表面的癌症(CRC ) pretreated。方法：十四个病人(中部的年龄 56 年) 与先进 CRC，都在基于 oxaliplatin 、基于 irinotecan 的联合化疗以后进行了，在这研究被注册。病人们与 irinotecan 的 2 h 注入被对待 d 上的 150 mg/m2 1 ，正 bevacizumab 为 d 上的 90 min 的 5 mg/kg iv 注入 2 ，并且 LV 20 mg/m2 的 iv 注射由 5-FU 的一丸大丸药跟随了 400 mg/m2 然后 22 h 在二连续的天给每 14 d 的 600 mg/m2 的连续注入。结果：化疗的周期的中部的数字是六(范围 3-12 ) 。反应率是 28.5% ，一个病人有完全的回答，并且三个病人有部分回答。八个病人有稳定的疾病。前进的中部的时间是 3.9 瞬间(95% CI 2.0-8.7 ) ，并且中部的全面幸存是 10.9 瞬间(95% CI 9.6-12.1 ) 。等级 3/4 嗜中性白血球减少症在五个病人发生了，并且这些中的二个得了 neutropenic 发烧。等级 3 血尿症和便血发生在一个。等级 2 蛋白尿发生在二个病人。然而，高血压，肠穿孔或 thromboembolic 事件没总共 90 个周期的发生。结论：有 FOLFIRI 的 Bevacizumab 很好被容忍并且在有重重地对待的先进 CRC 的病人的可行治疗。

关键词：甲酰四氢叶酸 5-氟脲嘧啶结肠直肠癌治疗药物

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Usefulness of colonic tattooing using indocyanine green in patients with colorectal tumors

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World Journal of Clinical Cases 2018年第13期6卷 632-640页

作者： Jae Ho Park Hee Seok Moon In Sun kwon Gee Young Yun Seo Hee Lee Dae Hwa Park Ju Seok Kim Sun Hyung Kang Eaum Seok Lee Seok Hyun Kim Jae Kyu Sung Byung Seok Lee Hyun Yong Jeong Division of Gastroenterology Department of Internal Medicine Chungnam National University Hospital Chungnam National University college of Medicine Clinical Trials Center Chungnam National University Hospital

AIM To prove that tattooing using indocyanine green(ICG) is feasible in laparoscopic surgery for a colon *** From January 2012 to December 2016, all patients who underwent laparoscopic colonic surgery were retrospectively screened, and 1010 patients with colorectal neoplasms were included. Their lesions were tattooed with ICG the day before the operation. The tattooed group(TG) included 114 patients, and the non-tattooed group(NTG) was selected by propensity score matching of subjects based on age, sex, tumor staging, and operation method(n = 228). In total, 342 patients were enrolled. Between the groups, the changes in [Delta(Δ), preoperative-postoperative] the hemoglobin and albumin levels, operation time, hospital stay, oral ingestion period, transfusion, and perioperative complications were compared. RESULTS Preoperative TG had a shorter operation time(174.76 ± 51.6 min vs 192.63 ± 59.9 min, P min(0.41 ± 0.44 g/dL vs 1.08 ± 0.39 g/dL, P min results than those of the N1 or N2 group. The operation methods affected the results, and laparoscopic anterior resection(LAR) showed similar results. However, for left and right hemicolectomy, both groups showed no difference in operation time or hospital *** Preoperative tattooing with ICG is useful for laparoscopic colectomy, especially in the N0 colon cancer group and LAR.

关键词： Colorectal neoplasm Laparoscopic surgery Endoscopic tattoo Indocyanine green Perioperative

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Effects of Trekking Pole Use on Metabolic Cost in Novice Hikers on Steep Terrains

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Journal of Sports Science 2017年第5期5卷 256-264页

作者： Yong Bin Han Ik Jin kwon Dae Taek Lee Eun Jin Hwang Jong Kwang Kim Eun Hyung Cho Graduate Program of Sports Engineering Convergence Kookmin University Seou102 707 Korea Department of Sports Health and Rehabilitation Kookmin University Seou102707 Korea Graduate School of Sports Natural Science Kookmin University Seou102707 Korea College of Sport Science Sung Kyun Kwan University Gyeonggi-do 16419 Korea

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Influences of tool plunge speed and tool plunge depth on friction spot joining of AA5454-O aluminum alloy plates with different thicknesses

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中国有色金属学会会刊：英文版 2012年第S3期22卷 629-633页

作者： Sung-Ook YOON Myoung-Soo KANG Yong-Jai kwon Sung-Tae HONG Dong-Hwan PARK Kwang-Hak LEE Chang-Yong LIM Jong-Dock SEO School of Materials Science and Engineering University of Ulsan School of Mechanical Engineering University of Ulsan Institute of E-Vehicle Technology University of Ulsan Technical Research Laboratories Shin Young Co.Ltd.

AA5454-O aluminum alloy plates with the thicknesses of 1.4 and 1.0 mm were friction-spot-joined (FSJed).The plunge speed of the joining tool was changed in a range of 100 500 mm/min under a constant rotation speed of 500 r/*** plunge depth was ranged from 1.6 mm to 2.2 *** tool plunge speed did not make a remarkable effect on the surface appearance and macro-structure of the FSJed *** average hardness of the FSJed zone was greater than or equal to that of the base ***,there was no remarkable tendency in the average hardness change of the FSJed zone in spite of the variation in the tool plunge speed and tool plunge *** increase of the tool plunge depth resulted in the increase of the tensile shear ***,the change of the tool plunge speed did not lead to the remarkable variation in the tensile shear load of the FSJed *** was noteworthy that the FSJed plate exhibited the highest tensile shear load of about 4.0 kN.

关键词： friction spot joining AA5454-O aluminum alloy plunge speed plunge depth mechanical property

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Friction stir butt welding of A5052-O aluminum alloy plates

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中国有色金属学会会刊：英文版 2012年第S3期22卷 619-623页

作者： Sung-Ook YOON Myoung-Soo KANG Hyun-Bin NAM Yong-Jai kwon Sung-Tae HONG Jin-Chun KIM Kwang-Hak LEE Chang-Yong LIM Jong-Dock SEO School of Materials Science and Engineering University of Ulsan School of Mechanical Engineering University of Ulsan Technical Research Laboratories Shin Young Co.Ltd.

Friction stir butt welding (FSW) between A5052-O aluminum alloy plates with a thickness of 2 mm was *** rotation speeds of the welding tool were 2000 and 3000 r/min,*** traverse speed was ranged from 100 mm/min to 900 mm/*** defect-free welds with the very smooth surface morphology were successfully obtained,except for at the welding condition of 3000 r/min and 100 mm/*** onion ring structure was observed in the friction-stir-welded zone (SZ) at the condition of 2000 r/min and 100 mm/*** all the welding conditions,the grain size of the SZ was smaller than that of the base metal,and was decreased with the decrease of the tool rotation speed and with the increase of the tool traverse *** stir zone exhibited higher average hardness than the base *** decrease of the tool rotation speed and the increase of the tool traverse speed resulted in the increase in the average hardness of the *** tensile strength of the FSWed plates was similar to that of the base metal,except for at the welding condition of 3000 r/min and 100 mm/*** total elongation of the FSWed plates was lower than that of the base metal.

关键词： friction stir butter welding A5052-O aluminum alloy microstructure mechanical property

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融合李群理论与特征子空间基的图像目标跟踪

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控制理论与应用 2012年第10期29卷 1272-1276页

作者：吴刚唐振民杨静宇南京理工大学计算机科学与技术学院江苏南京210094 南京工程学院车辆工程系江苏南京211167

针对复杂背景下目标跟踪窗口易受噪声干扰从而产生形变与漂移的问题,本文利用群空间中仿射群组受扰动后的形不变属性,将系统状态变量映射到李群空间进行处理,同时采用增量主元分析法(IPCA)算法实时学习并更新目标特征子空间数据.所提方... 详细信息

针对复杂背景下目标跟踪窗口易受噪声干扰从而产生形变与漂移的问题,本文利用群空间中仿射群组受扰动后的形不变属性,将系统状态变量映射到李群空间进行处理,同时采用增量主元分析法(IPCA)算法实时学习并更新目标特征子空间数据.所提方法在利用粒子滤波算法采样粒子时,通过引入测量向量以提高权值计算的准确性.在基于Car11等4个测试集的实验中,结果优于IVT跟踪器,本文跟踪器窗口在噪声干扰下不会产生形变,跟踪成功率达到96%,结果优于IVT跟踪器.对比kwon跟踪器,本文跟踪方法显著降低了算法复杂度,平均执行时间有效地控制在0.32s/帧.

关键词：目标识别群空间学习特征

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基于辣椒基因组测序探究辣味在种群中的进化

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辣椒杂志 2014年第2期12卷 40-50页

作者： Seungill Kim minkyu Park Seon-In Yeom Yong-min Kim Je min Lee Hyun-Ah Lee Eunyoung Seo Jaeyoung Choi Kyeongchae Cheong Ki-Tae Kim Kyongyong Jung Gir-Won Lee sang-Keun Oh Chungyun Bae Saet-Byul Kim Hye-Young Lee Shin-Young Kim Myung-Shin Kim Byoung-Cheorl Kang Yeong Deuk Jo Hee-Bum Yang Hee-Jin Jeong Won-Hee Kang Jin-Kyung kwon Chanseok Shin Jae Yun Lim June Hyun Park Jin Hoe Huh June-Sik Kim Byung-Dong Kim Oded Cohen Ilan Paran Mi Chung Suh Saet Buyl Lee Yeon-Ki Kim Younhee Shin Seung-Jae Noh Junhyung Park Young Sam Seo Suk-Yoon kwon Hyun A Kim Jeong Mee Park Hyun-Jin Kim sang-Bong Choi Paul W Bosland Gregory Reeves Sung-Hwan Jo Bong-Woo Lee Hyung-Taeg Cho Hee-Seung Choi min-Soo Lee Yeisoo Yu Yang Do Choi Beom-Seok Park Allen van Deynze Hamid Ashrafi Theresa Hill Woo Taek Kim Hyun-Sook Pai Hee Kyung Ahn Inhwa Yeam James J Giovannoni Jocelyn K C Rose Iben Sφrensen sang-Jik Lee Ryan W Kim Ik-Young Choi Beom-Soon Choi Jong-Sung Lim Yong-Hwan Lee Doil Choi 刘峰张西露 Department of Plant Science Seoul National University Plant Genomics and Breeding Institute Seoul National University Department of Agricultural Biotechnology Seoul National University Department of Bioinformatics and Life Science Soongsil University Vegetable Breeding Research Center Seoul National University Agricultural Research Organization Institute of Plant Science Volcani Center Bet DaganIsrael. Agricultural Research Organization Institute of Plant Science Volcani Center Bet DaganIsrael Department of Bioenergy Science and Technology Chonnam National University Genomics Genetics Institute GreenGene BioTech Inc. Codes Division Insilicogen Inc. Ginseng Resources Research Laboratory Korea Ginseng Corporation Korea Research Institute of Bioscience and Biotechnology Division of Bioscience and Bioinformatics Myongji University Department of Plant and Environmental Sciences New Mexico State University Chile Pepper Institute New Mexico State University Seeders Inc. Department of Biological Sciences Seoul National University Arizona Genomics Institute University of Arizona Agricultural Genome Center National Academy of Agricultural Science Rural Development Administration Seed Biotechnology Center University of California Davis Davis California USA Department of Systems Biology Yonsei University Department of Horticulture and Breeding Andong National University US Department of Agriculture-Agricultural Research Service Robert W. Holley Center Ithaca New York USA Boyce Thompson Institute for Plant Research Cornell University Ithaca New York USA Department of Plant Biology Cornell University Ithaca New York USA Biotechnology Institute Nongwoo Bio Yeoju Korea Genome Center University of California Davis Davis California USA National Instrumentation Center for Environmental Management Seoul National University Seoul Korea 湖南省蔬菜研究所

辣椒(Capsicum annuum)是美洲最古老的驯化作物之一,在全世界被广泛种植。本研究对CM334(墨西哥地方品种)进行了全基因组测序和组装(覆盖度为186.6×),同时还对另外两个栽培种和一个野生种分别进行了重测序和从头(de novo)测序。结果表... 详细信息

辣椒(Capsicum annuum)是美洲最古老的驯化作物之一,在全世界被广泛种植。本研究对CM334(墨西哥地方品种)进行了全基因组测序和组装(覆盖度为186.6×),同时还对另外两个栽培种和一个野生种分别进行了重测序和从头(de novo)测序。结果表明辣椒基因组大小约为番茄的4倍,辣椒基因组上存在大量gypsy转座子和花椰菜病毒家族元件的积累。结合转录组综合分析认为,辣椒素合成酶基因表达模式的改变及新功能化是导致辣椒素生物合成的原因,研究还发现辣椒与番茄在乙烯合成及果实成熟调控方面存在明显不同的分子模式。辣椒参考基因组的发布为辣椒营养品质和药用价值的改善提供了重要平台。

关键词：基因组测序辣椒素参考基因 Capsicum 转座子辣椒果实分子模式生物合成基因表达模式基因组大小

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Impact of regional geology, land use and flow path on stream water chemistry in a small watershed

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Chinese Journal Of Geochemistry 2006年第B8期25卷 140-140页

作者： Jae Gon Kim Jin-Soo Lee Kyung Seok Ko Tack Hyun Kim Chul-min Chon Gyoo Ho Lee Tong kwon Kim Yongje Kim Sung Won Park Korea Institute of Geoscience and mineral Resources Daejeon Korea Korea Atomic Energy Research Institute Daejeon Korea

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对我国女子跆拳道大级别运动员组合技术运用现状的分析

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北京体育大学学报 2006年第10期29卷 1431-1433页

作者：黄鹤蔡利敏王蓓蓓北京体育大学北京100084 华北电力大学(北京)体育教学部北京102206 对外经济贸易大学体育部北京100029

运用录像观察等研究方法,对我国女子跆拳道大级别运动员组合技术运用现状进行全面、系统的分析,结果认为:国内比赛组合技术的运用次数、击头次数、组合技术的成功率和组合技术种类均多于国际比赛,但组合技术击头的成功率低于国际比赛,... 详细信息

运用录像观察等研究方法,对我国女子跆拳道大级别运动员组合技术运用现状进行全面、系统的分析,结果认为:国内比赛组合技术的运用次数、击头次数、组合技术的成功率和组合技术种类均多于国际比赛,但组合技术击头的成功率低于国际比赛,当前国内外比赛组合技术运用次数是随技术数量的增加而减少的趋势,成功率是随动作数量的增加而增加的趋势等。并建议今后应该加强高频高得分组合的训练,提高成功率,加强高频失分组合抗失分训练。

关键词：跆拳道女子大级别组合技术

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