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Macroalgal deep genomics illuminate multiple paths to aquatic,photosynthetic multicellularity

Molecular Plant 2024年第5期17卷 747-771页

作者： David R.Nelson Alexandra Mystikou Ashish Jaiswal Cecilia Rad-Menendez Michael J.Preston Frederik De Boever Diana C.El assal Sarah Daakour Michael W.Lomas Jean-Claude Twizere David H.Green William C.Ratcliff Kourosh Salehi-Ashtiani Division of Science and Math New York University Abu DhabiAbu DhabiUAE Center for Genomics and Systems Biology(CGSB) New York University Abu DhabiAbu DhabiUAE Biotechnology Research Center Technology Innovation InstitutePO Box 9639Masdar CityAbu DhabiUAE Culture Collection of Algae and Protozoa Scottish Association for Marine ScienceObanScotlandUK National Center for Marine Algae and Microbiota Bigelow Laboratory for Ocean SciencesEast BoothbayMEUSA Laboratory of Viral Interactomes GIGA InstituteUniversity of LiegeLiegeBelgium School of Biological Sciences Georgia Institute of TechnologyAtlantaGAUSA

Macroalgae are multicellular,aquatic autotrophs that play vital roles in global climate maintenance and have diverse applications in biotechnology and eco-engineering,which are directly linked to their multicellularity ***,their genomic diversity and the evolutionary mechanisms underlying multicellularity in these organisms remain *** this study,we sequenced 110 macroalgal genomes from diverse climates and phyla,and identified key genomic features that distinguish them from their microalgal *** for cell adhesion,extracellular matrix formation,cell polarity,transport,and cell differentiation distinguish macroalgae from microalgae across all three major phyla,constituting conserved and unique gene sets supporting multicellular *** genes show phylum-and climate-specific expansions that may facilitate niche ***,our study reveals genetic determinants of convergent and divergent evolutionary trajectories that have shaped morphological diversity in macroalgae and provides genome-wide frameworks to understand photosynthetic multicellular evolution in aquatic environments.

关键词： macroalgae multicellularity comparative genomics evolution adhesome endogenous viral elements

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Design Methodology of a Micro-Scale 2-DOF Energy Harvesting Device for Low Frequency and Wide Bandwidth

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Journal of Sensor Technology 2014年第2期4卷 37-47页

作者： Mahmoud M. Magdy Ahmed M. R. Fath El-Bab Samy F. M. assal Mechatronics and Robotics Engineering Department Egypt-Japan University of Science and Technology Alexandria Egypt Mechatronics and Robotics Engineering Department Egypt-Japan University of Science and Technology Alexandria Egypt Production Engineering and Mechanical Design Department Faculty of Engineering Tanta University Tanta Egypt Mechatronics and Robotics Engineering Department Egypt-Japan University of Science and Technology Alexandria Egypt Mechanical Engineering Department Faculty of Engineering Assiut University Assiut Egypt

A detailed design methodology of a micro-scale 2-DOF energy harvesting device that can harvest human motion energy of low frequency and wide bandwidth is developed. Based on the concept of the 2-DOF vibration absorber, device parameters are selected to harvest energy at low frequency of 1-10 Hz and wide bandwidth with ±20% of the mean frequency, which matches the human motion. The device dimensions are limited to 40 × 30 × 10 mm3 to fit with the human wrist size. Then, a finite element model is developed to investigate the system performance with the selected parameters. When subjected to harmonic excitation of 1 g, the proposed 2-DOF device is able to provide a power of at least 10 μW in between the two close resonant peaks of 4 Hz and 6 Hz, which is the target frequency range. The device shows very high power per square frequency compared with the reported harvesters.

关键词： Energy Harvesting Two Degree of Freedom Low Frequency Wide Bandwidth

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A New Implant for Transfemoral Amputation: Improved Gait and Comfort

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Open Journal of Orthopedics 2021年第6期11卷 199-205页

作者： Mathieu assal Halah Kutaish Richard Stern Alice Bonnefoy-Mazure Antoine Acker Axel Gamulin Stephane Stephane Gorki Carmona Alain Lacraz Foot & Ankle Surgery Center Centre Assal Hirslanden Clinique La Colline Geneva Switzerland Faculty of Medicine Geneva University Geneva Switzerland Willy Taillard Laboratory of Kinesiology Geneva University Hospitals and Geneva University Geneva Switzerland Division of Orthopaedic Surgery and Traumatology University Hospitals of Geneva Geneva Switzerland

Introduction: Transfemoral amputation results in a prosthesis which bears weight on the ischium. Gait disturbance, lack of an end-bearing stump and discomfort in the groin from the socket even while sitting, are important issues. Methods: This is a pilot report of an ongoing randomized blind clinical trial of a new intramedullary implant post transfemoral amputation. Here, we describe a single case illustrating the surgical technique and clinical outcome of a dysfunctional post-traumatic transfemoral amputation addressed with this implant. Clinical gait analysis, SF-12 and VAS were assessed pre- and post-intervention at 6 months of follow-up. Results: An improved stump control is accomplished by means of myoplasty and myodesis through an end-cap. Stride width improved from 0.21 m pre-op to 0.13 m post-op, and more symmetrical stride length (△0.21 m pre-op vs. △0.06 m post-op) was noted, indicating improved gait quality and stability. Gait velocity increased (0.51 ± 0.04 m/s pre-op vs. 0.64 ± 0.02 m/s post-op). Conclusion: This technique reveals improvements in gait parameters in a transfemoral amputee treated with a new procedure. Improved prosthesis control, sitting comfort, greater hip range of motion, better gait stability, and enhanced walking abilities were noted.

关键词： Above Knee Amputation Transfemoral Amputation Gritti-Stokes Weight-Bearing End-Cap

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Rokcall score versus forrest classification in endoscopic management of bleeding peptic ulcer

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Health 2010年第6期2卷 634-638页

作者： Heba Sayed assal Ashraf Elsherbiny Hanan M. M. Badawy Ehab Hassan Nashaat Hesham al Shabrawi 不详

Acute upper gastrointestinal bleeding (UGIB) remains an important emergency situation. In the last two decades, major developments took place influencing incidence, etiology and outcome of patients with acute UGIB. Peptic ulcer bleeding is the most significant complication of ulcer disease being responsible for 50% of all cases mortality. Aim of the study: To compare between endoscopic clip application versus argon plasma coagulation in management of bleeding peptic ulcer (BPU). Patients and Methods: Sixty patients suffering from acute UGIB were randomly divided into two groups: group I included 30 patients treated with endoscopic clip application and Group II included 30 patients subjected to endoscopic APC. All patients were classified according to Forrest classification and the clinical Rockall score. Results: There were significant differences between the two groups as regard Forrest classification (P 0.05). Re bleeding was significant with higher Rockall score in group I (P 0.05). Conclusion: Endoscopic application of hemoclips have a less re bleeding rate than Argon plasma coagulation for treatment of bleeding peptic ulcer, although this was statistically insignificant, meanwhile APC is still less cost and easy. Clinical and endoscopic assessment (through Rokcall score and Forrest classification) could help in making best choice for endoscopic management.

关键词： Endoscope Bleeding Peptic Ulcer Argon Plasma Coagulation Clip Applications

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Automatic Heart Disease Diagnosis System Based on Artificial Neural Network (ANN) and Adaptive Neuro-Fuzzy Inference Systems (ANFIS) Approaches

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Journal of Software Engineering and Applications 2014年第12期7卷 1055-1064页

作者： Mohammad A. M. Abushariah assal A. M. Alqudah Omar Y. Adwan Rana M. M. Yousef Computer Information Systems Department King Abdullah II School for Information Technology The University of Jordan Amman Jordan

This paper aims to design and implement an automatic heart disease diagnosis system using?MATLAB. The Cleveland data set for heart diseases was used as the main database for training and testing the developed system. In order to train and test the Cleveland data set, two systems were developed. The first system is based on the Multilayer Perceptron (MLP) structure on the Artificial Neural Network (ANN), whereas the second system is based on the Adaptive Neuro-Fuzzy Inference Systems (ANFIS) approach. Each system has two main modules, namely, training and testing,?where 80% and 20% of the Cleveland data set were randomly selected for training and testing?purposes respectively. Each system also has an additional module known as case-based module,?where the user has to input values for 13 required attributes as specified by the Cleveland data set,?in order to test the status of the patient whether heart disease is present or absent from that particular patient. In addition, the effects of different values for important parameters were investigated in the ANN-based and Neuro-Fuzzy-based systems in order to select the best parameters that obtain the highest performance. Based on the experimental work, it is clear that the Neuro-Fuzzy system outperforms the ANN system using the training data set, where the accuracy for each system was 100% and 90.74%, respectively. However, using the testing data set, it is clear that the ANN system outperforms the Neuro-Fuzzy system, where the best accuracy for each system was 87.04% and 75.93%, respectively.

关键词： Heart Disease ANN ANFIS Multilayer Perceptron Neuro-Fuzzy Cleveland Data Set

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Prevalence of Cerebral Atherosclerosis among Patients with Metabolic Syndrome: A Case Control Study on Egyptian Subjects

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World Journal of Cardiovascular Diseases 2016年第1期6卷 8-13页

作者： Sherif Elwan Tarek Zoheir Tawfik Heba Sayed assal Shaimaa El-Jaafary Montasser Mohamed Hegazy Salwa Tawfik Alshaimaa Mahmoud Aboulfotooh Foad Abd-Allah Department of Internal Medicine National Research Institute Cairo Egypt Department of Neurology Cairo University Cairo Egypt

Background: The metabolic syndrome (MetS) is a clustering of vascular risk factors that tend to increase the risk of occurrence of diabetes mellitus type 2 (DMT2), cardiovascular and cerebro-vascular ischemic events. The aim of the present study is to investigate the association of extra-cranial and intracranial arterial atherosclerosis as well as silent brain infarction (SBI) with MetS, thereby determining the potential cerebrovascular atherosclerotic risk of MetS in the Egyptian population. Methods: A case control study was conducted on 50 Egyptian subjects with MetS and 30 without with age range from 40 - 60 years old. All participants were free from cerebrovascular ischemic events [stroke or transient ischemic attack (TIA)]. All participants underwent complete neurological examination, assessment of the diagnostic criteria for MetS, carotid and transcranial duplex ultrasonography (U/S) and brain MRI. Results: Preclinical carotid atherosclerosis (athero-sclerotic plaques with <50% stenosis) was associated with MetS (P value = 0.02) that persisted after adjustment for age and other confounders. There was no significant association between increased intima media thickness (IMT) and MetS. There was non-significant association between MetS and intracranial atherosclerotic disease (ICAD) or the degree of intracranial stenosis (ICS). Conversely, there was a highly significant association between MetS and SBI even after adjustment for age and other confounders (P value = 0.001). Conclusion: Metabolic syndrome is an important factor associated with mild to moderate atherosclerosis (<50% stenosis) and silent brain infarcts among asymptomatic individuals. Interventions to reduce MetS are important for prevention of subclinical and clinical cerebral atherosclerotic disease.

关键词： Metabolic Syndrome Preclinical Atherosclerosis Silent Brain Infarction Neurovascular Ultrasound Brain MRI Egyptian Population

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巴西标准化发展现状概述

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标准科学 2013年第8期 10-13页

作者：潘薇 Nelson Al assal Filho 魏利伟中国标准化研究院北京100191 The Associaoāo Brasileira de Normas Técnicas 圣保罗01258010

本文详细介绍了巴西标准化体系、标准化机构概况和标准制修订情况。作者利用较新的数据,对巴西标准制定和分布情况进行了介绍和说明。最后简要介绍了巴西合格评定体系、所涉及的监管机构以及所依据的相关标准。

关键词：标准化巴西标准

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The Management of Lumbosciatic Disc Related Disease at Renaissance University Teaching Hospital of N’Djamena-Chad: About 156 Cases

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Open Journal of Modern Neurosurgery 2023年第1期13卷 25-32页

作者： Goumantar Felicien Toudjingar Yannick Canton Kessely Ngaoussandjim Ndom-assal Olivier Ouambi Donald Djasde Mahouli Fata Vounki Alio Hamit Mahamat Momar Code Ba Department of Neurosurgery La Renaissance University Hospital N’Djamena Chad Department of Neurosurgery Reference Nationale University Hospital Center N’Djamena Chad Department of Neurosurgery Fann University Hospital Center Dakar Senegal

Introduction: Low back disc disease (LSD) is a neurosurgical condition with significant socioeconomic repercussions. The objective of this study was to determine the frequency and report the modalities of management. Methodology: This study on lumbosciatic disc disease was carried out in the neurosurgery department of the University Hospital Center (CHU), la Renaissance in N’Djamena. It covered a period of 12 months (from September 2019 to August 2020). A descriptive and an analytical approach were used. The variables studied were epidemiology, clinic, radiology and therapy. Results: the results showed that LSD represented 14.7% of the reasons for consultation in neurosurgery. The average age was 45.8, and to some extent, it ranges between 18 and 76. Lifting was the main reason behind lumbosciatic disc disease with 35.9% of cases, followed by a sedentary life style which represents 30.8%. Lumbosciatica L5 was noted in 49.4%. Obesity and overweight were significant risk factors (P = 0.02) reported in 59% of cases. Motor and sensory deficits were observed in 14.8% and 17.3% of cases, respectively. CT of the lumbar spine was performed in 91% and MRI in 28.9%. The L4-L5 disc herniation represented 74.3% of cases, with a lateral location in 44.2% and L5 radicular impingement in 30.8%. Conservative treatment was instituted in 87.2% and surgical treatment in 12.8% of cases. Conclusion: LSD is caused by a sedentary lifestyle, physical work and overweight. Surgery deals with complicated cases and cases not responding to conservative treatment.

关键词： Lumbosciatica Herniated Disc Surgical Treatment Conservative Treatment Chad

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一个DJ的梦与愁——《萨米尔的奇遇》访谈

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北京电影学院学报 2019年第6期 88-92页

作者：阿尔朵夫·艾尔·阿萨尔赵斌陈雪颜(翻译) 不详北京电影学院中国电影学院中国电影文化研究院

赵斌(以下简称“赵”):《萨米尔的奇遇》(Sawah)是一部带有浓烈自传色彩的音乐剧情片,讲述了一个疯狂逐梦的音乐人在欧洲奇妙而又略带伤感的经历。你选择创作了一个和音乐有关的剧情片,它可以被视作带有自传色彩的电影吗?

关键词：自传色彩音乐人剧情片电影

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等离子电源:空气/多种气体组合等离子精密切割解决方案

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金属加工（热加工） 2012年第6期 22-22页

作者： Alaaeldin A.assal ESAB OEM GLOBAL CUTTING TECHNOLOGY GROUP

ESABOEMGLOBALCUTTJNGTECHNOLOGYGROUP作为世界上最大的焊接和切割设备供应商之一，一直秉承着“COMEGROWwITHUS”的宗旨为用户提供高性能组件。如空气／多种气体混合的等离子解决方案一一利用等离子电源结合灵活的高性能割炬，实现更... 详细信息

ESABOEMGLOBALCUTTJNGTECHNOLOGYGROUP作为世界上最大的焊接和切割设备供应商之一，一直秉承着“COMEGROWwITHUS”的宗旨为用户提供高性能组件。如空气／多种气体混合的等离子解决方案一一利用等离子电源结合灵活的高性能割炬，实现更大功率，切割工艺更先进，是传统火焰切割的最佳替代产品。

关键词：精密切割气体混合等离子空气电源设备供应商切割工艺替代产品

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