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Clinical and computed tomography findings of appendiceal diverticulitis vs acute appendicitis

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World Journal of Gastroenterology 2015年第13期21卷 3921-3927页

作者： Daisuke Ito Kenji miki Shimizu Seiichiro Shojiro Hata Kaoru Kobayashi Masanori Teruya Michio Kaminishi Department of Gastro- intestinal Surgery Showa General HospitalTokyo 187--8510Japan Department of Pathology Showa General HospitalTokyo 187-8510Japan

AIM: To study the clinical features and computed tomography(CT) findings of appendiceal diverticulitis vs acute ***: We retrospectively reviewed the records of 451 patients who had undergone appendectomy inour in stitution from January 2007 to September 2012. Patient demographics, clinical features, pathological findings, and surgical outcomes were analyzed. We also compared preoperative CT images of 25 patients with appendiceal diverticulitis with those of 25 patients with acute ***: Among 451 patients, 44(9.7%) were diagnosed to have appendiceal diverticulitis and 398(86.9%) to have acute appendicitis. Patients with appendiceal diverticulitis were older(59 vs 37 years, P < 0.001) and had a longer duration of the illness(4.0 d vs 1.0 d, P < 0.001). Perforation rates in patients with appendiceal diverticulitis were higher(68% vs 27%, P < 0.001). The appendix could be visualized in only 13 patients(52%) among the appendiceal diverticulitis cases, but in all acute appendicitis cases. CT findings suggestive of appendiceal diverticulitis included the absence of fluid collection in the appendix(84% vs 12%, P < 0.001), absence of appendicolith(92% vs 52%, P = 0.005), and formation of abscess(68% vs 16%, P < 0.001). Appendiceal diverticula were identified in 6 patients(24%).CONCLUSION: Among patients who had undergone appendectomy, 9.7% had appendiceal diverticulitis. Patients with appendiceal diverticulitis had different clinical features and CT findings from patients with acute appendicitis.

关键词： Appendiceal diverticulitis Acute appendicitis Comp

Reproducible reformation of a bilayer lipid membrane using microair bubbles

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Droplet 2023年第3期2卷 90-98页

作者： Izumi Hashimoto Toshihisa Osaki Hirotaka Sugiura Hisatoshi Mimura Sho Takamori Norihisa miki Shoji Takeuchi Artificial Cell Membrane Systems Group Kanagawa Institute of Industrial Science and TechnologyKanagawaJapan Department of Mechanical Engineering Keio UniversityKanagawaJapan Institute of Industrial Science The University of TokyoTokyoJapan Graduate School of Information Science and Technology The University of TokyoTokyoJapan

Planar bilayer lipid membranes(BLMs)are widely used as models for cell membranes in various applications,including drug discovery and ***,the nanometer-thick bilayer structure,assembled through hydrophobic interactions of amphiphilic lipid molecules,makes such BLM systems mechanically and electrically *** this study,we developed a device to reform BLMs using a microair *** device consists of a double well divided by a separator with a microaperture,where a BLM was formed by infusing a lipiddispersed solvent and an aqueous droplet into each well in *** the BLM ruptured,a microair bubble was injected from the bottom of the well to split the merged aqueous droplet at the microaperture,which resulted in the reformation of two lipid monolayers on the split *** bringing the two droplets into contact,a new BLM was *** angled step design was introduced in the BLM device to guide the bubble and ensure the splitting of the merged *** also elucidated the optimal bubble inflow rate for the reproducible BLM *** a 4-channel parallel device,we demonstrated the individual and repeatable reformation of *** approach will aid the development of automated and arrayed BLM systems.

关键词： bubble bringing unstable

Extract of Emblica officinalis enhances the growth of human keratinocytes in culture

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Journal of Integrative Medicine 2019年第2期17卷 141-146页

作者： Yoshimi Yamakami Kyoko Morino Yuki Takauji Ryuichiro Kasukabe Kensuke miki Mohammad Nazir Hossain Dai Ayusawa Michihiko Fujii Graduate School of Nanobioscience Yokohama City University Ichiban Life Corporation Department of Biochemistry Primeasia University

Objective: Keratinocytes are the predominant cell type in the epidermis and play key roles in epidermal function. Thus, identification of the compounds that regulate the growth of keratinocytes is of importance. Here we searched for such compounds from the herbs used in traditional medicine ***: Human keratinocytes were cultured in the presence or absence of the herbal extracts for 2 weeks; the effect of the extracts on cell growth was determined by staining the cells with Coomassie brilliant blue. To detect the compounds that regulate the growth of keratinocytes, the herbal extracts were subjected to high-performance liquid chromatography(HPLC).Results: We found that the extract of Emblica officinalis enhanced the growth of keratinocytes in ***, we fractionated the extract of E. officinalis using HPLC and identified the fractions responsible for the enhanced growth of ***: The extract of E. officinalis enhanced the growth of human keratinocytes in culture.E. officinalis contains the compounds that would be beneficial for human skin health because enhanced growth of keratinocytes would promote wound healing.

关键词： Keratinocyte Cell growth Ayurveda Emblica officinalis

A Hydrogen-Bonded,Hexagonally Networked,Layered Framework with Large Aperture Designed by Structural Synchronization of a Macrocycle and Supramolecular Synthon

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Precision Chemistry 2024年第5期2卷 221-228页

作者： Hiroki Yoshimura Ryusei Oketani miki Naruoka Norimitsu Tohnai Ichiro Hisaki Division of Chemistry Graduate School of Engineering ScienceOsaka UniversityToyonakaOsaka 560-8531Japan Department of Applied Chemistry Graduate School of EngineeringOsaka UniversitySuitaOsaka 565-0871Japan

To develop porous organic frameworks,precise control of the stacking manner of two-dimensional porous motifs and structural characterization of the resultant framework are *** these points of view,porous molecular crystals formed through reversible intermolecular hydrogen bonds,such as;hydrogen-bonded organic frameworks(HOFs),can provide deep insight because of their high crystallinity,affording single-crystalline X-ray diffraction *** this study,we demonstrate that the stacking manner of hydrogen-bonded hexagonal network(HexNet)sheets can be controlled by synchronizing a homological triangular macrocyclic tecton and a hydrogen-bonded cyclic supramolecular synthon called the phenylene triangle.A structure of the resultant HOF was crystallographically characterized and revealed to have a large channel aperture of 2.4 *** HOF also shows thermal stability up to 290°C,which is higher than that of the conventional HexNet frameworks.

关键词： hydrogen-bonded organicframeworks hexagonalnetwork macrocycle carboxylicacid porosity

Protein and non-protein sulfhydryls and disulfides in gastric mucosa and liver after gastrotoxic chemicals and sucralfate: Possible new targets of pharmacologic agents

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World Journal of Gastroenterology 2007年第14期13卷 2053-2060页

作者： Lajos Nagy miki Nagata Sandor Szabo Departments of Pathology Brigham & Women's Hospital Harvard Medical SchoolBostonMassachusetts 02115and Pathology and Laboratory Medicine ServiceDiagnostic & Molecular Medicine HCGVA Medical Center9901 East 7th St. Long BeachCA 90822United States Depts. of 3rd Internal Medicine and Family MedicineFaculty of MedicineUniversity of PecsH-7632 PecsHungary Departments of Pathology Brigham & Women's Hospital Harvard Medical SchoolBostonMassachusetts 02115and Pathology and Laboratory Medicine ServiceDiagnostic & Molecular Medicine HCGVA Medical Center9901 East 7th St. Long BeachCA 90822United States

AIM： To investigate the role of major non-protein and protein sulfhydryls and disulfides in chemically induced gastric hemorrhagic mucosal lesions （HML） and the mechanism of gastroprotective effect of sucralfate.METHODS： Rats were given 1 mL of 75% ethanol, 25%NaCl, 0.6 mol/L HCI, 0.2 mol/L NaOH or 1% ammonia solutions intragastrically （i.g.） and sacrificed 1, 3, 6 or 12 min later. Total （reduced and oxidized） glutathione （GSH ＋ GSSG）, glutathione disulfide （GSSG）, protein free sulfhydryls （PSH）, protein-glutathione mixed disulfides （PSSG） and protein cystine disulfides （PSSP） were measured in gastric mucosa and liver.RESULTS： Reduced glutathione （GSH） was depleted in the gastric mucosa after ethanol, HCI or NaCl exposure,while oxidized glutathione （GSSG） concentrations increased, except by HCI and NaOH exposure. Decreased levels of PSH after exposure to ethanol were observed,NaCl or NaOH while the total protein disulfides were increased. Ratios of reduced to oxidized glutathione or sulfhydrils to disulfides were decreased by all *** changes in thiol homeostasis were detected in the liver after i.g. abbreviation should be spelled out the first time here administration of ethanol. Sucralfate increased the concentrations of GSH and PSH and prevented the ethanol-induced changes in gastric mucosal thiol concentrations.CONCLUSION： Our modified methods are now suitable for direct measurements of major protein and nonprotein thiols/disulfides in the gastric mucosa or liver.A common element in the pathogenesis of chemically induced HML and in the mechanism of gastroprotective drugs seems to be the decreased ratios of reduced and oxidized glutathione as well as protein sulfhydryls and disulfides.

关键词： Non-protein and protein thiol Gastricmucosal injury Gastroprotection Sucralfate

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纯天然手作果酱

在RHIC-PHENIX中(s_(NN))^(1/2)=200GeV Au+Au碰撞中直接光子的椭圆流测量(英文)

2017年

作者： miki

本书收录了数十款人气果酱配方，从单品果酱、双种果酱，到加入香料、花草等的复合果酱，凝聚了果酱达人多年的实践经验，还总结了如何挑选水果、如何调味、如何保存果酱等实用知识。此外，本书还列举了若干道果酱料理食谱，从前菜、沙...

ISBN: (数字)9787518414406

本书收录了数十款人气果酱配方，从单品果酱、双种果酱，到加入香料、花草等的复合果酱，凝聚了果酱达人多年的实践经验，还总结了如何挑选水果、如何调味、如何保存果酱等实用知识。此外，本书还列举了若干道果酱料理食谱，从前菜、沙拉、点心到饮品，超过50种果酱的吃法一一公开。按照本书的方法制作果酱，不仅简单方便，而且滋味绝佳，轻轻松松就能为家中的餐桌增添生趣。

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来源：汇雅图书（南通市图书馆... 评论

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高能物理与核物理 2007年第12期31卷 1174-1176页

作者： Kentaro miki for the PHENIX Collaboration University of Tsukuba Tsukuba Ibaraki 305Japan

Azimuthal anisotropy of direct photon is measured in S_(NN)^(1/2)=200GeV Au+Au collisions at RHIC- *** photon is one of the most effective probes to study properties of hot dence medium at initial state(also QGP state)of heavy ion collisions because photons almost do not interact strongly with any other particles caused by its long mean free path and they keep their conditions when they axe *** statistical and systematic errors,the elliptic flow parameter(v_2)of direct photon is consistent with zero. Direct photon v_2 is estimated by hadron decay photon contamination are subtracted from inclusive photon v_2 in intermediate to high transverse momentum(p_T)region(0 to 10GeV/c)for 3 centrality selections(20% steps)and minimum bias.

关键词：椭圆流热密集物质金离子碰撞 RHIC 光子

The International Prostate Forum introduction and history

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Asian Journal of Andrology 2015年第6期17卷 863-863,I0006页

作者： John W Davis Tsuneharu miki Atif Akdas Hiroki Watanabe Ziya Kirkali Run Wang R Joseph Babaian Department of Urology The University of Texas MDAnderson Cancer Center Houston Texas 77030 USA Department of Urology Kyoto Prefectural University ofMedicine Kyoto Japan Department of Urology Schoolof Medicine Marmara University Istanbul Turkey Watanabe Memorial Choumei Research Laboratory Shiga Japan Dokuz EylOI University School ofMedicine Department of Urology Izmir Turkey Division of Urology University of Texas Medical Schoolat Houston Department of Urology Houston TexasUSA Department of Urology University of Texas MDAnderson Cancer Center Houston Texas 77030 USA

The International Prostate Forum （IPF） originally started with three urology departments in Japan, Turkey, and the United States. The forum emphasized discussions and presentations of new knowledge in all areas of prostate diseases with an early emphasis on ultrasound and diagnostics. The meeting has generally run every 2 years and rotated through the three sites with new leadersjoining the effort. Over the years, the meeting has enjoyed a diverse locale and points of emphasis. The latter agendas now cover all aspects of the benign prostate disease, prostate cancer screening, prostate cancer diagnosis and staging, and therapies. Table 1 summarizes the dates of the meetings, locations, and chairman.

关键词： International Prostate history

Novel Radio on Fiber Access Eliminating External Electric Power Supply at Base Station

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光学学报 2003年第S1期23卷 611-612页

作者： Tetsuya miki Katsuyasu Kawano Nobuo Nakajima Naoto Kishi Masaru Miyamoto Tetsu Aoki The University of Electro-Communications Tokyo JapanThe University of Electro-Communications Tokyo JapanThe University of Electro-Communications Tokyo JapanThe University of Electro-Communications Tokyo JapanIwatsu Co. LTD. Tokyo Japan 1-5-1 Chohugaoka Chohu-shi Tokyo 182-8585 JapanIwatsu Co. LTD. Tokyo Japan 1-5-1 Chohugaoka Chohu-shi Tokyo 182-8585 Japan

A novel Radio On Fiber(ROF) access is proposed and demonstrated which enables the pico-cell Base Station (BS) for high-speed wireless communications to eliminate external electric power supply facilities. We demonstrated 2.4-GHz band radio signal transmission through the BS without external electric power supply. The electrical power used for BS circuit is feeded by optical power over optical fiber from central station.

关键词： Radio be ROF BS LNA link Novel Radio on Fiber Access Eliminating External Electric Power Supply at Base Station EAM