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Anthropogenic land use substantially increases riverine CO_(2) emissions

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Journal of Environmental Sciences 2022年第8期34卷 158-170页

作者： Shijie Gu Siyue Li Isaac R.santos School of River and Ocean Engineering Chongqing Jiaotong UniversityChongqing 400074China Key Laboratory of Reservoir Aquatic Environment Chongqing Institute of Green and Intelligent TechnologyChinese Academy of SciencesChongqing 400714China Chongqing School University of Chinese Academy of SciencesChongqing 400714China Research Center for Environmental Ecology and Engineering Institute of Changjiang Water Environment and Ecological SecuritySchool of Environmental Ecology and Biological EngineeringKey Laboratory for Green Chemical Process of Ministry of EducationKey Laboratory of Novel Reactor and Green Chemical Technology of Hubei ProvinceEngineering Research Center of Phosphorus Resources Development and Utilization of Ministry of EducationWuhan Institute of TechnologyWuhan 430205China Department of Marine Sciences University of GothenburgGothenburg 41296Sweden National Marine Science Centre Southern Cross UniversityCoffs HarbourNSW 2450Australia

Carbon dioxide(CO_(2)) emissions from inland waters to the atmosphere are a pivotal component of the global carbon budget. Anthropogenic land use can influence riverine CO_(2) emissions, but empirical data exploring cause-effect relationships remain limited. Here, we investigated CO_(2) partial pressures(pCO_(2)) and degassing in a monsoonal river(Yue River)within the Han River draining to the Yangtze in China. Almost 90% of river samples were supersaturated in CO_(2) with a mean ± standard deviation of 1474 ± 1614 μatm, leading to emissions of 557-971 mmol/m^(2)/day from river water to the atmosphere. Annual CO_(2) emissions were 1.6-2.8 times greater than the longitudinal exports of riverine dissolved inorganic and organic carbon. pCO_(2) was positively correlated to anthropogenic land use(urban and farmland), and negatively correlated to forest cover. p CO_(2) also had significant and positive relationships with total dissolved nitrogen and total dissolved phosphorus. Stepwise multiple regression models were developed to predict p CO_(2) . Farmland and urban land released nutrients and organic matter to the river system, driving riverine p CO_(2) enrichment due to enhanced respiration in these heterotrophic rivers. Overall, we show the crucial role of land use driving riverine pCO_(2) , which should be considered in future large-scale estimates of CO_(2) emissions from streams. Land use change can thus modify the carbon balance of urban-river systems by enhancing river emissions, and reforestation helps carbon neutral in rivers.

关键词： River carbon Inland waters Greenhouse gases Climate change Water quality Headwater streams

Exact Computation of the Topology and Geometric Invariants of the Voronoi Diagram of Spheres in 3D

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Journal of Computer Science & Technology 2013年第2期28卷 255-266页

作者： Franois Anton Darka Mioc Marcelo santos Research Division of Geodesy National Space Institute Technical University of Denmark Department of Geodesy and Geomatics Engineering University of New Brunswick

In this paper, we are addressing the exact the Voronoi diagram of spheres using Wu＇s algorithm. computation of the Delaunay graph （or quasi-triangulation） and Our main contributions are first a methodology for automated derivation of invariants of the Delaunay empty circumsphere predicate for spheres and the Voronoi vertex of four spheres, then the application of this methodology to get all geometrical invariants that intervene in this problem and the exact computation of the Delaunay graph and the Voronoi diagram of spheres. To the best of our knowledge, there does not exist a comprehensive treatment of the exact computation with geometrical invariants of the Delaunay graph and the Voronoi diagram of spheres. Starting from the system of equations defining the zero-dimensional algebraic set of the problem, we are applying Wu＇s algorithm to transform the initial system into an equivalent Wu characteristic （triangular） set. In the corresponding system of algebraic equations, in each polynomial （except the first one）, the variable with higher order from the preceding polynomial has been eliminated （by pseudo-remainder computations） and the last polynomial we obtain is a polynomial of a single variable. By regrouping all the formal coefficients for each monomial in each polynomial, we get polynomials that are invariants for the given problem. We rewrite the original system by replacing the invariant polynomials by new formal coefficients. We repeat the process until all the algebraic relationships （syzygies） between the invariants have been found by applying Wu＇s algorithm on the invariants. Finally, we present an incremental algorithm for the construction of Voronoi diagrams and Delaunay graphs of spheres in 3D and its application to Geodesy.

关键词： Voronoi diagram of spheres Delaunay graph of spheres Wu's method invariant characteristic set

Probing intensity-field correlations of single-molecule surface-enhanced Raman-scattered light

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Frontiers of physics 2019年第6期14卷 15-26页

作者： O.de los santos-Sanchez Instituto de Ciencias Físicas Universidad Nacional Autónoma de MéxicoApdo.Postal 48-3CuernavacaMorelos 62251México

In the context of the quantum-mechanical description of single-molecule surface-enhanced Raman scattering,intensity-field correlation measurements of photons emitted from a plasmonic cavity are explored,theoretically,using the technique of conditional homodyne *** inelastic interplay between plasmons and vibrations of a diatomic molecule placed inside the cavity can be manifested in phase-dependent third-order fluctuations of the light recorded by the aforesaid technique,allowing us to reveal signatures of non-classicality(indicatives of squeezing)of the outgoing Raman photons.

关键词： Raman scattering SERS phase-dependent fluctuations squeezing plasmonics

Adipose stromal/stem cells in regenerative medicine:Potentials and limitations

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World Journal of Stem Cells 2020年第1期12卷 1-7页

作者： Leandra santos Baptista Multidisciplinary Center for Biological Research (Numpex-Bio) Federal University of Rio de Janeiro (UFRJ) Campus Duque de Caxias Post-graduate Program in Biotechnology National Institute of MetrologyQuality and Technology (INMETRO) Post-graduate Program in Translational Biomedicine (Biotrans) UnigranrioCampus Ⅰ Laboratory of Tissue Bioengineering Directory of Metrology Applied to Life SciencesNational Institute of MetrologyQuality and Technology(INMETRO)

This article presents the stem and progenitor cells from subcutaneous adipose tissue,briefly comparing them with their bone marrow counterparts,and discussing their potential for use in regenerative *** adipose tissue differs from other mesenchymal stromal/stem cells(MSCs)sources in that it contains a pre-adipocyte population that dwells in the adventitia of robust blood ***-adipocytes are present both in the stromal-vascular fraction(SVF;freshly isolated cells)and in the adherent fraction of adipose stromal/stem cells(ASCs;in vitro expanded cells),and have an active role on the chronic inflammation environment established in obesity,likely due their monocyticmacrophage lineage *** SVF and ASCs have been explored in cell therapy protocols with relative success,given their paracrine and immunomodulatory ***,the widely explored multipotentiality of ASCs has direct application in bone,cartilage and adipose tissue *** aim of this editorial is to reinforce the peculiarities of the stem and progenitor cells from subcutaneous adipose tissue,revealing the spheroids as a recently described biotechnological tool for cell therapy and tissue *** cell culture techniques,in particular 3D scaffold-free cultures such as spheroids,are now available to increase the potential for regeneration and differentiation of mesenchymal *** are being explored not only as a model for cell differentiation,but also as powerful 3D cell culture tools to maintain the stemness and expand the regenerative and differentiation capacities of mesenchymal cell lineages.

关键词： Mesenchymal stromal/stem cells Subcutaneous adipose tissue Stromalvascular fraction Adipose stromal/stem cells Regenerative medicine Cell therapy Tissue engineering Spheroids

Natural orifice translumenal endoscopic surgery: Progress in humans since white paper

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World Journal of Gastroenterology 2011年第13期17卷 1655-1665页

作者： Byron F santos Eric S Hungness Department of Surgery Feinberg School of Medicine Northwestern University Chicago IL 60611 United States

Since the first description of the concept of natural orifice translumenal endoscopic surgery (NOTES), a substantial number of clinical NOTES reports have appeared in the literature. This editorial reviews the available human data addressing research questions originally proposed by the white paper, including determining the optimal method of access for NOTES, developing safe methods of lumenal closure, suturing and anastomotic devices, advanced multitasking platforms, addressing the risk of infection, managing complications, addressing challenges with visualization, and training for NOTES procedures. An analysis of the literature reveals that so far transvaginal access and closure appear to be the most feasible techniques for NOTES, with a limited, but growing transgastric, transrectal, and transesophageal NOTES experience in humans. The theoretically increased risk of infection as a result of NOTES procedures has not been substantiated in transvaginal and transgastric procedures so far. Development of suturing and anastomotic devices and advanced platforms for NOTES has progressed slowly, with limited clinical data on their use so far. Data onthe optimal management and incidence of intraoperative complications remain sparse, although possible factors contributing to complications are discussed. Finally, this editorial discusses the likely direction of future NOTES development and its possible role in clinical practice.

关键词： Natural orifice translumenal endoscopic surgery Outcomes Complications Endoscopic Surgery

Capacitorless Solid-state Power Filter for Single-phase DC-AC Converters

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CES Transactions on Electrical Machines and Systems 2024年第3期8卷 367-377页

作者： Haitham Kanakri Euzeli C.Dos santos Purdue University Electrical and Computer Engineering DepartmentIndianapolisIN46202 USA

Converters rely on passive filtering as a crucial element due to the high-frequency operational characteristics of power *** filtering methods involve a dual inductor-capacitor(LC)cell or an inductor-capacitor-inductor(LCL)***,capacitors are susceptible to wear-out mechanisms and failure ***,the necessity for monitoring and regular replacement adds to an elevated cost of ownership for such *** utilization of an active output power filter can be used to diminish the dimensions of the LC filter and the electrolytic dc-link capacitor,even though the inclusion of capacitors remains an indispensable part of the *** paper introduces capacitorless solid-state power filter(SSPF)for single-phase dc-ac *** proposed configuration is capable of generating a sinusoidal ac voltage without relying on *** proposed filter,composed of a planar transformer and an H-bridge converter operating at high frequency,injects voltage harmonics to attain a sinusoidal output *** design parameters of the planar transformer are incorporated,and the impact of magnetizing and leakage inductances on the operation of the SSPF is *** analysis,supported by simulation and experimental results,are provided for a design example for a single-phase *** total harmonic distortion observed in the output voltage is well below the IEEE 519 *** system operation is experimentally tested under both steady-state and dynamic conditions.A comparison with existing technology is presented,demonstrating that the proposed topology reduces the passive components used for filtering.

关键词： Solid-state power filter(SSPF) Capacitorless topology Active output power filter(AOF) Planar transformer Electrolytic capacitor Lifetime Wear-out mechanisms

LL-37 and CsgC exemplify the crosstalk between anti-amyloid, antimicrobial, and anti-biofilm protein activities

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Neural Regeneration Research 2023年第5期18卷 1027-1028页

作者： Jaime santos Salvador Ventura Irantzu Pallares Institut de Biotecnologia i Biomedicina Departament de Bioquímica i Biologia Molecular Universitat Autònoma de Barcelona

Protein misfolding and aggregation into amyloid fibrils is the main pathological hallmark of neurodegenerative diseases,including Alzheimer’s,Parkinson’s,Huntington’s,and prion diseases(Chiti and Dobson,2017).These insoluble fibrillar deposits possess a common structure characterized by a cross-β-sheet conformation in which β-strands run transversely to the fiber axis and form an intermolecular network of hydrogen bonds.

关键词： amyloid Huntington diseases

Pharmacological therapy used in the elimination of Helicobacter pylori infection:A review

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World Journal of Gastroenterology 2015年第1期21卷 139-154页

作者： Ariolana A dos santos Adriana A Carvalho Department of Pharmacy Federal University of SergipeCampus Lagarto49400-00 LagartoSergipeBrazil

The optimal therapy for Helicobacter pylori(***) infection should combine a high cure rate and a short treatment duration with a favorable side-effect profile and should maintain a low *** strategies have been proposed to increase the *** eradication rate,including the extension of the treatment duration to 14 d,the use of a four-drug regimen(quadruple,sequential,and concomitant treatments),and the use of novel antibiotics,such as ***,triple therapy remains the most widely accepted firstline treatment regimen in Brazil and the United Statesand throughout *** this therapy is limited by resistance to clarithromycin,other therapeutic regimens have been investigated *** review describes the current literature involving studies directly comparing these different therapies and their efficacies.

关键词： Clarithromycin resistant Helicobacter pylori Pepti

Dynamic response surface methodology using Lasso regression for organic pharmaceutical synthesis

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Frontiers of Chemical Science and Engineering 2022年第2期16卷 221-236页

作者： Yachao Dong Christos Georgakis Jacob santos-Marques Jian Du Institute of Chemical Process Systems Engineering School of Chemical EngineeringDalian University of TechnologyDalian 116024China Department of Chemical and Biological Engineering and Systems Research Institute Tufts UniversityMedfordMA 02155USA

To study the dynamic behavior of a process,time-resolved data are collected at different time instants during each of a series of experiments,which are usually designed with the design of experiments or the design of dynamic experiments *** utilizing such time-resolved data to model the dynamic behavior,dynamic response surface methodology(DRSM),a datadriven modeling method,has been *** approaches can be adopted in the estimation of the model parameters:stepwise regression,used in several of previous publications,and Lasso regression,which is newly incorporated in this paper for the estimation of DRSM ***,we show that both approaches yield similarly accurate models,while the computational time of Lasso is on average two magnitude *** case studies are performed to show the advantages of the proposed *** the first case study,where the concentrations of different species are modeled directly,DRSM method provides more accurate models compared to the models in the *** second case study,where the reaction extents are modeled instead of the species concentrations,illustrates the versatility of the DRSM ***,DRSM with Lasso regression can provide faster and more accurate datadriven models for a variety of organic synthesis datasets.

关键词： data-driven modeling pharmaceutical organic synthesis Lasso regression dynamic response surface methodology