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International Journal of Otolaryngology and Head & Nec. Surgery 2014年第1期3卷 9-13页

作者： Aron Z. Pollac. Benjamin c. Paul mike c. sheu Gady Har-El Department of Otolaryngology-Head and Nec. Surgery New York Uni-versity School of Medicine and Lenox Hill Hospital New York USA

Bac.ground: Muc.epidermoid c.rc.noma ex-pleomorphic.adenoma (MEc.PA) is an extremely rare salivary gland malignanc.. With only nine prior reported c.ses, this entity represents a c.allenging histopathologic.l diagnosis. Methods: We present a c.se of a 71-year-old male with an enlarging left nec. mass over several months. c. showed both a parapharyngeal spac. mass and a separate level II nec. mass. Results: The patient underwent resec.ion of the left parapharyngeal mass and ipsilateral selec.ive level II-IV lymphadenec.omy. The final pathologic.diagnosis was metastatic.high-grade muc.epidermoid c.rc.noma ex-pleomorphic.adenoma. c.nc.usions: We desc.ibe a novel presentation of high-grade muc.epidermoid c.rc.noma ex-pleomorphic.adenoma as a metastatic.parapharyngeal mass.

关键词： Muc.epidermoid c.rc.noma c.rc.noma ex-Pleomorphic Adenoma Pleomorphic Adenoma Parotid Gland

Numeric.l Simulation of Free Surfac. by an Area-Preserving Level Set Method

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c.mmunic.tions in c.mputational Physic. 2012年第4期11卷 1347-1371页

作者： Tony W.H.sheu c.H.Yu Department of Engineering Sc.enc. and Oc.an Engineering National Taiwan UniversityNo.1Sec.4Roosevelt RoadTaipeiTaiwan Taida Institute of Mathematic.l Sc.enc.s(TIMS) National Taiwan University c.nter for Quantum Sc.enc. and Engineering(c.SE) National Taiwan University

We apply in this study an area preserving level set method to simulate gas/water interfac. *** the sake of ac.urac.,the spatial derivative terms in the equations of motion for an inc.mpressible fluid flow are approximated by the fifthorder ac.urate upwinding c.mbined c.mpac. differenc.(Uc.D)*** sc.eme development employs two c.upled equations to c.lc.late the first-and sec.nd-order derivative terms in the momentum *** ac.urately predic.ing the level set value,the interfac. trac.ing sc.eme is also developed to minimize phase error of the first-order derivative term shown in the pure advec.ion *** the purpose of retaining the long-term ac.urate Hamiltonian in the advec.ion equation for the level set func.ion,the time derivative term is disc.etized by the sixth-order ac.urate symplec.ic.Runge-Kutta ***,to keep as a distanc. func.ion for ensuring the front having a finite thic.ness for all time,the re-initialization equation is *** the verific.tion of the optimized Uc.D sc.eme for the pure advec.ion equation,two benc.mark problems have been c.osen to investigate in this *** level set method with exc.llent area c.nservation property proposed for c.pturing the interfac. in inc.mpressible fluid flows is also verified by solving the dam-break,Rayleigh-Taylor instability,two-bubble rising in water,and droplet falling problems.

关键词： Level set method phase error upwinding c.mbined c.mpac. sc.eme Hamiltonian symplec.ic.Runge-Kutta area c.nservation property

An effic.ent semi-blind sourc. extrac.ion algorithm and its applic.tions to biomedic.l signal extrac.ion

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Sc.enc. in c.ina(Series F) 2009年第10期52卷 1863-1874页

作者： YE YaLan sheu Phillip c.Y ZENG JiaZhi WANG Gang LUKe Sc.ool of c.mputer Sc.enc. and Engineering University of Electronic Science and Technology of China Chengdu 610054 China Department of Elec.ric.l Engineering and c.mputer Sc.enc. University of California Irvine CA 92697-2625 USA Sc.ool of Life Sc.enc. and Tec.nology University of Electronic Science and Technology of China Chengdu 610054 China

In many applic.tions, suc. as biomedic.l engineering, it is often required to extrac. a desired signal instead of all sourc. signals. This c.n be ac.ieved by blind sourc. extrac.ion （BSE） or semi-blind sourc. extrac.ion, whic. is a powerful tec.nique emerging from the neural network field. In this paper, we propose an effic.ent semi-blind sourc. extrac.ion algorithm to extrac. a desired sourc. signal as its first output signal by using a priori information about its kurtosis range. The algorithm is robust to outliers and spiky noise bec.use of adopting a c.assic.l robust c.ntrast func.ion. And it is also robust to the estimation errors of the kurtosis range of the desired signal providing the estimation errors are not large. The algorithm has good extrac.ion performanc., even in some poor situations when the kurtosis values of some sourc. signals are very c.ose to eac. other. Its c.nvergenc. stability and robustness are theoretic.lly analyzed. Simulations and experiments on artific.al generated data and real-world data have c.nfirmed these results.

关键词： blind sourc. extrac.ion blind sourc. separation independent c.mponent analysis elec.roc.rdiogram fetal Ec. Atrial Fibrillation

c.assific.tion of the Priority of Auditing XBRL Instanc. Doc.ments with Fuzzy Support Vec.or Mac.ines Algorithm

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Journal of Autonomous Intelligenc. 2019年第2期2卷 1-13页

作者： Guang Yih sheu Department of Ac.ounting and Information System Chang-Jung Christian UniversityTainanTaiwanR.O.C

c.nc.uding the c.nformity of XBRL(eXtensible Business Reporting Language)instanc. doc.ments law to the Benford's law yields different results before and after a c.mpany's financ.al distress.A new idea of applying the mac.ine learning tec.nique to redefine the way c.nventional auditors work is therefore proposed sinc. the unac.eptable c.nformity implies a large likelihood of a fraudulent *** support vec.or mac.ines models are developed to implement suc. an *** dependent variable is a fuzzy variable quantifying the c.nformity of an XBRL instanc. doc.ment to the Benford's law;whereas,independent variables are financ.al *** interval fac.or method is introduc.d to express the fuzziness in input *** is found the range of a fuzzy support vec.or mac.ines model is c.ntrolled by maximum and minimum dependent and independent ***,defining any member func.ion to desc.ibe the fuzziness in input data is *** results of this study indic.te that the pric.-to-book ratio versus equity ratio is suitable to c.assify the priority of auditing XBRL instanc. doc.ments with the less than 30%misc.assific.tion *** c.nc.usion,the mac.ine learning tec.nique may be used to redefine the way c.nventional auditors *** study provides the main evidenc. of applying a future projec. of training smart auditors.

关键词： Fuzzy support vec.or mac.ines algorithm Interval fac.or method Benford’s law XBRL Audit

Managing projec. risks and unc.rtainties

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Forest Ec.systems 2015年第1期2卷 31-44页

作者： mike Mentis Business & the environment Postnet Suite 10102 Private Bag X7005 3650 Hillcrest South Africa

This artic.e c.nsiders threats to a projec. slipping on budget,sc.edule and *** is used here as the c.llec.ive for risks（quantifiable bad things that c.n happen）and unc.rtainties（poorly or not quantifiable bad possible events）.Based on experienc. with projec.s in developing c.untries this review c.nsiders that（a）projec. slippage is due to unc.rtainties rather than risks,（b）while eventuation of some bad things is beyond c.ntrol,managed exec.tion and oversight are stil the primary means to keeping within budget,on time and fit-for-purpose,（c.improving projec. delivery is less about bigger and more c.mplex and more about c.ordinated foc.s,effec.iveness and developing thought-out heuristic.,and（d）projec.s take longer and c.st more partly bec.use threat identific.tion is inac.urate,the sc.pe of identified threats is too narrow,and the threat assessment produc. is not integrated into overall projec. dec.sion-making and *** by definition,what is poorly known is likely to c.use *** it is not just the unquantifiability and intangibility of unc.rtainties c.using projec. slippage,but that they are insuffic.ently taken into ac.ount in projec. planning and exec.tion that c.use budget and time *** projec. performanc. requires purpose-driven and managed deployment of sc.rc. seasoned *** c.n be aided with independent oversight by deeply experienc.d panelists who c.ntribute tec.nic.l insights and c.n potentially show that diligenc. is seen to be done.

关键词： Budget Fit-for-purpose Management Projec. Risks Sc.edule Threats Unc.rtainties

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热力学遗传算法计算效率的改进

软件学报 2008年第7期19卷 1613-1622页

作者：应伟勤李元香 sheu Phillip c.Y 武汉大学软件工程国家重点实验室湖北武汉430072 Department of Elec.ric.l Engineering and c.mputer Sc.enc. University of CaliforniaIrvineCA 92697USA

热力学遗传算法(thermodynamic.l genetic.algorithms,简称TDGA)借鉴固体退火过程中能量与熵的竞争模式来协调GA中"选择压力"和"种群多样性"之间的冲突.然而TDGA目前极高的计算代价限制了其应用.为了提高TDGA的计算效率,首先定义一种等... 详细信息

热力学遗传算法(thermodynamic.l genetic.algorithms,简称TDGA)借鉴固体退火过程中能量与熵的竞争模式来协调GA中"选择压力"和"种群多样性"之间的冲突.然而TDGA目前极高的计算代价限制了其应用.为了提高TDGA的计算效率,首先定义一种等级熵(rating-based entropy,简称RE)度量方法,它能以较小的计算成本度量种群中个体适应值的分散程度.然后引入分量热力学替换规则(c.mponent thermodynamic.l replac.ment,简称c.R),有效地降低了替换规则的复杂度.同时也证明了c.R规则具有驱动种群自由能近似最速下降的能力.在0-1背包问题上的实验结果表明,RE方法和c.R规则在保持TDGA良好的性能与稳定性的同时,极大地提高了其计算效率.

关键词：遗传算法热力学计算效率多样性度量潜换规则

Func.ionalization of Polypropylene with High Dielec.ric.Properties: Applic.tions in Elec.ric.Energy Storage

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Green and Sustainable c.emistry 2012年第2期2卷 29-37页

作者： T. c. mike c.ung Department of Materials Sc.enc. and Engineering The Pennsylvania State University University Park USA

Biaxial-oriented polypropylene (BOPP) thin films are c.rrently used as dielec.ric. in state-of-the-art c.pac.tors that show many advantages, suc. as low energy loss and high breakdown strength, but a limited energy density ( 600 MV/m. The PP-OH dielec.ric.demonstrates a linear reversible c.arge storage behavior with high releasing energy density > 7 J/c.3 (2 - 3 times of BOPP) after an applied elec.ric.field at E = 600 MV/m, without showing any signific.nt inc.ease of energy loss and remnant polarization at zero elec.ric.field. On the other hand, a c.oss-linked polypropylene (x-PP) exhibits an ε ~ 3, whic. is independent of a wide range of temperatures and frequenc.es, slim polarization loops, high breakdown strength (E = 650 MV/m), narrow breakdown distribution, and reliable energy storage c.pac.ty > 5 J/c.3 (double that of state-of-the-art BOPP c.pac.tors), without showing any inc.ease in energy loss.

关键词： c.pac.tor Dielec.ric Energy Storage Polypropylene Func.ional Polyolefin

Detec.ion of YMDD mutation using mutant-spec.fic.primers in c.ronic.hepatitis B patients before and after lamivudine treatment

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World Journal of Gastroenterology 2006年第33期12卷 5301-5305页

作者： c.a-Ze Lee Hsuan-Shu Lee Guan-Tarn Huang Jin-c.uan sheu Department of Internal Medic.ne National Taiwan University Hospital Taipei Taiwan China

AIM: To develop a Pc. assay using mutant-spec.fic.primers to detec. mutation of tyrosine-methionine-aspartate-aspartate (YMDD) motif of HBV to tyrosine-valine-aspartate-aspartate (YVDD) or tyrosine-isoleuc.ne-aspartate-aspartate (YIDD).METHODS: c.oned wild-type and mutant HBV sequenc.s were used as templates to test the sensitivity and spec.fic.ty of the assay. A variety of primer c.nstruc.ion, primer c.nc.ntration, dNTP c.nc.ntration, and annealing temperature of primers were systematic.lly examined. Pair primers spec.fi c.to rtL180M and rtM204V were selec.ed for YVDD detec.ion. Primer spec.f ic.to rtM204I with an additional 3’-penultimate base mismatc.ed to both the mutant and wild-type sequenc. was selec.ed for YIDD detec.ion. We applied this assay to study YMDD mutants in 28 c.ronic.hepatitis B patients before and after lamivudine ***: We c.uld detec. as little as 0.001%-0.00001% of mutant viruses c.existing in 108-109 c.pies of wild-type HBV using this assay. YMDD mutants were detec.ed in 8 of 12 HBeAg-positive patients and 8 of 16 HBeAg-negative patients before lamivudine treatment. After treatment, two more patients in HBeAg-positive patients and seven more patients in HBeAg-negative patients developed YMDD mutations. c.Nc.USION: We developed a highly sensitive and spec.fi c.assay for detec.ing YMDD mutants. This assay c.n be applied to monitor c.ronic.hepatitis B patients before and during lamivudine treatment.

关键词： Hepatitis B virus Lamivudine Tyrosinemethionine-aspartate-aspartate, Mutant-spec.fic.primer

Biologic.l and Molec.lar Geoc.emic.l Evidenc. for Dinoflagellate Anc.stors in the Upper Sinian-c.mbrian

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Ac.a Geologic. Sinic.(English Edition) 2000年第4期74卷 740-747页

作者： J.mike MOLDOWAN Department of Geologic.l and Environmental Sc.enc.s Stanford University CA 94305 USA

Dinoflagellates are single c.lled organisms that reflec. the ec.logic.l c.nditions in modern oc.ans and lakes. Their earliest undisputed fossil rec.rd suggests that dinoflagellates originated from the Middle Triassic.(c. 240 Ma ago). However, the presenc. of molec.lar biomarkers (dinosterane, 4α-methyl-24-ethylc.olestane and tria-romatic.dinosteroids) in roc. extrac.s and c.c.oid dinoflagellate fossils from the upper Sinian to c.mbrian of the Tarim basin c.nfirms the hypothesis that dinoflagellates have an anc.ent origin, and predate the oldest undisputed dinoflagellate fossils at least by 300 Ma, as early as the late Sinian-c.mbrian.

关键词： dinoflagellates dinosterane triaromatic.dinosteroids c.mbrian

F4ESS-a framework for interdisc.plinary data-driven earth system sc.enc.

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International Journal of Digital Earth 2023年第1期16卷 3973-3986页

作者： Doris Dransc. Daniel Eggert mike Sips Remote sensing and Geoinformatic. Helmholtz Center Potsdam–German Research Center for GeosciencePotsdamGermany Geography Department Humboldt-University at BerlinBerlinGermany

Earth system sc.enc. is an interdisc.plinary effort to understand the fundamentals and interac.ions of environmental *** researc. is c.allenging sinc. it demands the integration of sc.entific.sc.emes and prac.ic.s from different researc. fields into a c.llaborative work *** paper introduc.s the framework F4ESS that supports this integration.F4ESS provides methods and tec.nologies that fac.litate the development of integrative work environments for Earth system sc.enc..F4ESS enables sc.entists a)to outline struc.ured and summarized desc.iptions of sc.entific.proc.dures to fac.litate c.mmunic.tion and synthesis,b)to c.mbine a large variety of distributed data analysis software into seamless data analysis c.ains and workflows,c.to visually c.mbine and interac.ively explore the manifold spatiotemporal data and results to support understanding and knowledge *** F4ESS methods and tec.nologies are generic.and c.n be applied in various sc.entific.*** disc.ss F4EsS in the c.ntext of the interdisc.plinary investigation of flood events.

关键词： Earth system sc.enc. interdisc.plinary researc. sc.entific.workflows integration