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High-Grade Gliomas 2007

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丛书名： Current Clinical Oncology

2007年

作者： Gene H. barnett

ebook ISBN:1597451851

ISBN: (数字)9781597451857

ISBN: (纸本)9781588295118

ebook ISBN:1597451851

关键词： Glioma

来源：畅想之星图书光盘版（南... 评论

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畅想之星图书光盘版（南通市图书馆镜像）

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把教学与研究联系起来——一项首要的课题

现代远距离教育 1996年第4期 77-80页

作者：陈明 RONALD barnett 黑龙江省林业设计院

把教学与研究联系起来——一项首要的课题ＲＯＮＡＬＤＢＡＲＮＥＴＴ著陈明译序言高等教育与研究之间的关系是什么？说到这种关系自然就提出这样一个问题，两者之间是否存在着概念上的联系。很明显，在高等学府里确实进行着很多科学研... 详细信息

把教学与研究联系起来——一项首要的课题ＲＯＮＡＬＤＢＡＲＮＥＴＴ著陈明译序言高等教育与研究之间的关系是什么？说到这种关系自然就提出这样一个问题，两者之间是否存在着概念上的联系。很明显，在高等学府里确实进行着很多科学研究工作。我们在英国的各个大学里可能...

关键词：科学研究工作教学与研究高等教育中心高等学府科研成果科研工作学术界研究者研究人员学术成就

Recovery rates of combination antibiotic therapy using in vitro microdialysis simulating in vivo conditions

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Journal of Pharmaceutical Analysis 2018年第6期8卷 407-412页

作者： Jayesh A.Dhanani Suzanne L.Parker Jeffrey Lipman Steven C.Wallis Jeremy Cohen John Fraser Adrian barnett Michelle Chew Jason A.Roberts Burns Trauma and Critical Care Research Centre The University of Queensland UQ Centre for Clinical Research Department of Intensive Care Medicine Royal Brisbane & Women's Hospital Faculty of Health Queensland University of Technology Critical Care Research Group The University of Queensland Institute of Health and Biomedical Innovation & School of Public Health and Social Work Queensland University of Technology Department of Anaesthesiology and Intensive Care and Department of Medical and Health Sciences Link?ping University School of Pharmacy The University of Queensland Department of Pharmacy Royal Brisbane & Women's Hospital

Microdialysis is a technique used to measure the unbound antibiotic concentration in the interstitial spaces, the target site of action. In vitro recovery studies are essential to calibrating the microdialysis system for in vivo studies. The effect of a combination of antibiotics on recovery into microdialysate requires investigation. In vitro microdialysis recovery studies were conducted on a combination of vancomycin and tobramycin, in a simulated in vivo model. Comparison was made between recoveries for three different concentrations and three different perfusate flow rates. The overall relative recovery for vancomycin was lower than that of tobramycin. For tobramycin, a concentration of 20μg/mL and flow rate of 1.0μL/min had the best recovery. A concentration of 5.0μg/mL and flow rate of 1.0μL/min yielded maximal recovery for vancomycin. Large molecular size and higher protein binding resulted in lower relative recoveries for vancomycin. Perfusate flow rates and drug concentrations affected the relative recovery when a combination of vancomycin and tobramycin was tested. Low perfusate flow rates were associated with higher recovery rates. For combination antibiotic measurement which includes agents that are highly protein bound, in vitro studies performed prior to in vivo studies may ensure the reliable measurement of unbound concentrations.

关键词： Microdialysis Combination antibiotic therapy Relative recovery rate Pharmacokinetics Anti-infectives Protein binding

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显微镜下看亚马孙河

疯狂英语（初中天地） 2006年第8期 33-36页

作者： Adrian barnett 方嘉乐

我们将与亚德里安·巴聂特同行前往亚马孙盆地,他的渊博学识与丰富经验使他成为我们的理想导游,可以带我们沿着宽阔的亚马孙河,寻找珍贵的野生动植物。

关键词：亚马孙河马瑙斯节目主持人显微镜下

A Review of an Unorthodox Argatroban Infusion Rate for Anticoagulation in a Patient Case

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Journal of Pharmacy and Pharmacology 2017年第4期5卷 189-193页

作者： Erin barnett Loesch Christopher Ryan Boldi Dayton Veterans Affairs Medical Center Dayton Ohio 45428 USA

Argatroban is an intravenous DTI （direct synthetic thrombin inhibitor） that is not routinely used for anticoagulation; thus, expertise surrounding its use is very limited. Therefore, this case reviews an unusually high argatroban infusion rate, which was needed to prevent further emboli formation in a patient. In this case, a 61-year-old Caucasian male patient exhibited heparin resistance during an intraoperative vascular procedure as measured by activated clotting time and PTT （partial thromboplastin time）. The patient had multiple occlusions in his right lower extremities and underwent embolectomies of the right popliteal and posterior tibial arteries. The clinical pharmacist was consulted to manage the argatroban infusion once heparin was discontinued. The therapeutic window required a PTr of 1.5-3 times the patient baseline （35-75 s）. The patient was reported to be 89 kg with a baseline PTT of 24.7 s and INR （international normalized ratio） of 0.98. The starting dose ofargatroban was initiated by the pharmacist at 2 mcg/kg/min （10.7 mL/h） as the patient did not have hepatic failure or sepsis. The patient was maintained on argatroban in the therapeutic PTT window for more than 72 h; however, frequent and aggressive dose increases, to a final rate of 7.5 mcg/kg/min （40 mL/h）, were needed to maintain the therapeutic PTT level. From the case, the cause of heparin resistance still has not been determined despite a hematologic work-up; however, this patient required an unusually high infusion rate of argatroban to maintain a therapeutic PTT during the hospital course before being changed to an anticoagulation regimen for discharge.

关键词： Anticoagulation argatroban direct thrombin inhibitor heparin resistance partial thromboplastin time.

Meta-Study of Particulate Detection Losses on Radioactive Air Sample Filters

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Journal of Environmental Protection 2022年第8期13卷 589-602页

作者： J. Matthew barnett Hunter Z. Edwards Pacific Northwest National Laboratory Richland USA

Several mathematical relationships between air sample filter mass loading and the correlated analytical self-absorption factor were developed using data from other published research in this meta-study. Gross-alpha and -beta applications are addressed for this research. As filter media becomes loaded with particulate matter, there is potential for measurement losses due to self-absorption by mass loading. Components contributing to absorption include particulate dust, radioactive particulates, and filter material. Standards indicate a correction factor should be used when the penetration of radioactive material into the collection media or self-absorption of radiation by the material collected would reduce the detection rate by more than 5%. Previously, losses due to self-absorption have been reported up to 100% over a range up to ~10 mg⋅cm-2 mass loading. These absorption losses then can be used to determine a correction factor for sample results. For low mass loadings (e.g., ≤0.1 mg⋅cm-2) corrections factors in the 0.85 - 1 range have been recommended and used, while at higher mass loadings nearer to 10 mg⋅cm-2 correction factors closer to 0 (representing near 100% losses) are used. Based on data from published studies, the different methods for relating percent loss due to self-absorption to mass loading include linear, exponential, quadratic, and trinomial derived functions. Where applicable, both forced zero and non-forced zero results were evaluated. From the derived functions evaluated, the trinomial function provided the best fit. Once the sample filter mass loading is known, the trinomial function can be applied to estimate losses and the corresponding self-absorption factor. When applied to routine operating conditions for radiological facility stacks monitored at the Pacific Northwest National Laboratory for an average sample filter mass loading of 0.09 ± 0.12 (2σ) mg⋅cm-2 (excluding negative values and outliers

关键词： Air Sampling Environmental Radioactivity Self-Absorption Correction Factor Standards

医疗人员对居住在新西兰克赖斯特彻奇的中国人的精神卫生服务状况的观点(英文)

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上海精神医学 2013年第6期25卷 375-383页

作者：张秋红 Jeffrey GAGE Pauline barnett 中国天津市精神卫生中心(天津安定医院) School of Health Sciences University of Canterbury

背景:移民会给人带来压力,也有可能会提高在海外居住的中国人的精神疾病患病率。文化习俗和服务的缺乏也许会阻碍他们寻求所需的精神卫生服务。目的:评估新西兰的医疗人员关于来自中国大陆的移民对精神卫生服务的使用状况的观点。方法:... 详细信息

背景:移民会给人带来压力,也有可能会提高在海外居住的中国人的精神疾病患病率。文化习俗和服务的缺乏也许会阻碍他们寻求所需的精神卫生服务。目的:评估新西兰的医疗人员关于来自中国大陆的移民对精神卫生服务的使用状况的观点。方法:本定性研究在新西兰克赖斯特彻奇完成。研究者深入访谈了9名有服务中国客户经验的精神卫生专业人员,并把访谈内容进行笔录以及主题分析。结果:访谈内容中出现了四个主题:(1)中国移民的特殊心理问题;(2)移民中最容易出现心理问题的人群;(3)妨碍获得服务的因素;(4)社会支持网络对中国移民的心理健康的重要性。结论:通过对高收入国家中为日益增长的中国大陆移民提供心理健康服务的医疗人员的定性研究,可以找出需要提高对文化的敏感度的地方,以此来增加中国移民对精神卫生服务的利用,提高服务的效率。

关键词：心理健康问题服务提供者中国人新西兰精神疾病卫生问题居住供给

Colorful facial markings are associated with foraging rates and affiliative relationships in a wild group-living cichlid fish

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Current Zoology 2024年第1期70卷 70-78页

作者： Brett M.Culbert James B.barnett Isaac Y.Ligocki Matthew G.Salena Marian Y.L.Wong Ian M.Hamilton Sigal Balshine Department of Integrative Biology University of GuelphGuelphOntarioCanada Department of Psychology Neuroscience&BehaviourMcMaster UniversityHamiltonOntarioCanada Department of Evolution Ecologyand Organismal BiologyThe Ohio State UniversityColumbusOHUSA Department of Biology Millersville UniversityMillersvillePAUSA School of Earth Atmospheric and Life SciencesUniversity of WollongongWollongongNew South WalesAustralia Department of Mathematics The Ohio State UniversityColumbusOHUSA

Many animals use color to signal their quality and/or behavioral *** signals have been well studied in the contexts of competi-tion and mate choice;however,the role of these signals in nonsexual,affiliative relationships is not as well ***,we used wild social groups of the cichlid fish Neolamprologus pulcher to investigate whether the size of a brightly colored facial patch was related to 1)individual quality,2)social dominance,and/or 3)affiliative *** with larger patches spent more time foraging and tended to perform more aggressive acts against conspecific territory *** did not find any evidence that the size of these yellow patches was related to social rank or body size,but dominant males tended to have larger patches than dominant ***,patch size had a rank-specific relationship with the number of affiliative interactions that individuals engaged *** males with large patches received fewer affiliative acts from their groupmates compared to dominant males with small ***,subordinates with large patches tended to receive more affiliative acts from their groupmates while performing fewer affiliative acts *** together,our results suggest that patch size reflects interindividual variation in foraging effort in this cichlid fish and offer some of the first evidence that colorful signals may shape affiliative relationships withinwildsocialgroups.

关键词： affiliation foraging Lake Tanganyika Neolamprologus pulcher visual signals

Theoretical Application to Understand Food Insecurity Among College Students: A Multi-Systems Life Course Perspective

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Sociology Study 2019年第2期9卷 75-83页

作者： Tracey Marie barnett Reina Olivo Valandra Kameri Christy University of Arkansas FayettevilleUSA

Empirical studies have shown a distinct relationship between academic performance and food insecurity in college students. Specifically, food-insecure students are more likely to report a lower grade point average than their food secure counterparts. Since the Great Recession, more attention has been given to the topic of hunger and food insecurity among college students;however, the literature still lacks a comprehensive examination of various issues facing today’s college students. Using a multi-systems life course (MSLC) perspective, this paper provides a conceptual explanation of the lived experience of college students by offering a better understanding of the unique challenges faced by this population. Findings from this study will assist researchers, practitioners, and university administrators in their efforts to address hunger among this population.

关键词： multi-systems life course perspective hunger food insecurity college students university