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It is Time for a Change： oPetri Dishes Weaken Cells

Journal of Bionic Engineering 2012年第3期9卷 353-357页

作者： Andrei P. Sommer mike kh. haddad Hans-Joerg Fecht Institute of Micro and Nanomaterials University of Ulm 89081 Ulm Germany Institute for Nanotechnology Karlsruhe Institute for Technology 76344 Eggenstein-Leopoldshafen Germany

We wish to draw the attention to a potential deficiency in the biocompatibility of polystyrene cell culture dishes which is caused by a softening of the material under relevant culture conditions. The finding confirms the central hypothesis of our previous model study. In it we assumed a local increase in pH at the interface between the hydrophilic polymer and liquid. The finding is of considerable biological interest. Polystyrene tissue culture dishes are now in use for 50 years. To the best of our knowledge their biocompatibility has never been challenged. Here we report the first experimental proof that exposure to water softens the surface of polystyrene Petri dishes. We expect that our results will stimulate the development of a new generation of cell culture devices, including Petri dishes and culture flasks, and the establishment of improved biomimetic settings for tissue engineering and stem cell research. New non-swelling biomaterials or nanocoatings designed to reduce the swelling of polymer ct, lture dishes could improve cell performance. The need for further study is clear.

关键词： Petri dish polystyrene biomimetic triangle nanoindentation stem cells diamond

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Quark-hadron phase transition in DGP including BD brane

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Chinese Physics C 2020年第8期44卷 98-107页

作者： Tayeb Golanbari Terife haddad Abolhassan Mohammadi M.A.Rasheed kh.Saaidi Department of Physics Faculty of ScienceUniversity of KurdistanPasdaran St.P.O.Box 66177-15175SanandajIran Department of Physics Faculty of ScienceRazi UniversityKermanshah ***Iran Development Center for Research and Training(DCRT) University of Human DevelopmentSulaimaniKurdistan RegionIraq Department of Physics College of ScienceUniversity of SulaimaniKurdistan RegionIraq

A Dvali–Gabadadze–Porrati(DGP)brane-world model with perfect fluid brane matter including a Brans-Dicke(BD)scalar field on brane was utilized to investigate the problem of the quark-hadron phase(QHP)transition in early evolution of the *** presence of the BD scalar field arises with several modified terms in the Friedmann *** the behavior of the phase transition strongly depends on the basic evolution equations,even a small change in these relations might lead to interesting results about the time of *** phase transition is investigated in two scenarios,namely the first-order phase transition and smooth crossover phase *** the first-order scenario,which is used for the intermediate temperature regime,the evolution of the physical quantities,such as temperature and scale factor,are investigated before,during,and after the phase *** results show that the transition occurs in about a *** the following part,the phenomenon is studied by assuming a smooth crossover transition,where the lattice QCD data is utilized to obtain a realistic equation for the state of the *** investigation for this part is performed in the high and low-temperature *** the trace anomaly in the high-temperature regime specifies a simple equation of state,which states that the quark-gluon behaves like ***,in the low-temperature regime,the trace anomaly is affected by discretization effects,and the hadron resonance gas model is utilized *** this model,a more realistic equation of state is found in the low-temperature *** crossover phase transition in both regimes is *** results determine that the transition lasts around a few ***,the transition in the low-temperature regime occurs after the transition in the high-temperature regime.

关键词： DGP brane-world quark-hadron phase lattic QCD

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