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The Italian Catquest-9SF cataract questionnaire: translation, validation and application

Eye and Vision 2016年第1期3卷 89-96页

作者： Eirini Skiadaresi Giuseppe Ravalico Silvio Polizzi Mats Lundstrom miguel gonzalez-andrades Colm McAlinden University Eye Clinic of Trieste Ospedale MaggioreTriesteItaly Department of Ophthalmology Singleton HospitalABM University Health BoardSwansea SA28QAUK Department of Clinical Sciences OphthalmologyFaculty of MedicineLund UniversityLundSweden Cornea&Refractive Surgery Service Massachusetts Eye&Ear InfirmaryDepartment of OphthalmologyHarvard Medical SchoolBostonUSA ABM University Health Board SwanseaUK Flinders University Bedford ParkAdelaideSouth AustraliaAustralia Wenzhou Medical University WenzhouZhejiangChina

Background:To validate the Catquest-9SF questionnaire in Italian,assess the change in visual disability with cataract surgery and determine the correlation between pre-operative Catquest-9SF scores and Lens Opacities Classification System(LOCS)III cataract ***:Prospective,questionnaire validation *** Catquest-9SF questionnaire was forward and back translated and completed by 209 Italian patients before and three months following cataract *** analysis was used to assess its psychometric ***:The Italian Catquest-9SF demonstrated ordered response categories,unidimensionality(item fit statistics range:0.73–1.34),adequate person separation(2.04),and no differential item *** was evident with a mean difference in item difficulty and person ability of 2.04 logits but improved with inclusion of pre-operative data *** was a statistically significant(Friedman tests,p<0.001)median improvement in visual disability of 1.92,3.57,1.44 and 2.94 logits in patients undergoing first eye surgery with and without ocular comorbidity,and second eye surgery with and without ocular comorbidity *** was no statistically significant difference in the improvements among the four groups(Kruskal-Wallis H test,X^(2)(3)=5.445,p=0.142).There was no correlation between Catquest-9SF scores and nuclear opalescence(r_(s)=0.049,p=0.478),nuclear colour(r_(s)=0.008,p=0.909),cortical(r_(s)=0.066,p=0.341),and posterior subcapsular components(r_(s)=0.048,p=0.494).Conclusions:The Italian Catquest-9SF demonstrated good psychometric properties and is suitable for use in Italian speaking *** were similar improvements in visual disability in patients undergoing first or second eye surgery,with or without ocular *** was no correlation between pre-operative Catquest-9SF scores and LOCS III cataract grading.

关键词： Catquest-9SF Questionnaires Patient-reported outcomes Cataract Cataract surgery Rasch analysis

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Task Offloading in Edge Computing Using GNNs and DQN

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Computer Modeling in Engineering & Sciences 2024年第6期139卷 2649-2671页

作者： Asier Garmendia-Orbegozo Jose David Nunez-gonzalez miguel Angel Anton Department of Applied Mathematics University of the Basque Country UPV/EHUEibar20600Spain TECNALIA Basque Research and Technology Alliance(BRTA)San Sebastian20009Spain

In a network environment composed of different types of computing centers that can be divided into different layers(clod,edge layer,and others),the interconnection between them offers the possibility of peer-to-peer task *** many resource-constrained devices,the computation of many types of tasks is not feasible because they cannot support such computations as they do not have enough available memory and processing *** this scenario,it is worth considering transferring these tasks to resource-rich platforms,such as Edge Data Centers or remote cloud *** different reasons,it is more exciting and appropriate to download various tasks to specific download destinations depending on the properties and state of the environment and the nature of the *** the same time,establishing an optimal offloading policy,which ensures that all tasks are executed within the required latency and avoids excessive workload on specific computing centers is not *** study presents two alternatives to solve the offloading decision paradigm by introducing two well-known algorithms,Graph Neural Networks(GNN)and Deep Q-Network(DQN).It applies the alternatives on a well-known Edge Computing simulator called PureEdgeSimand compares them with the two defaultmethods,Trade-Off and Round *** showed that variants offer a slight improvement in task success rate and workload *** terms of energy efficiency,they provided similar ***,the success rates of different computing centers are tested,and the lack of capacity of remote cloud servers to respond to applications in real-time is *** novel ways of finding a download strategy in a local networking environment are unique as they emulate the state and structure of the environment innovatively,considering the quality of its connections and constant *** download score defined in this research is a crucial feature for determining the quality of a download path

关键词： Edge computing edge offloading fog computing task offloading

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Pollen analysis reveals the effects of uncovered interactions,pollen-carrying structures,and pollinator sex on the structure of wild bee-plant networks

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Insect Science 2024年第3期31卷 971-988页

作者： Clément Tourbez Carmelo Gómez-Martínez miguelÁngel gonzalez-Estévez Amparo Lazaro Mediterranean Institute for Advanced Studies(UIB-CSIC) Global Change Research GroupEsporlesBalearic IslandsSpain Department of Biology Ecology AreaUniversity of the Balearic/slandsPalmaSpain

Pollination networks are increasingly used to model the complexity of interactions between pollinators and flowering plants in *** methods exist to sample these interactions,with direct observations of plant-pollinator contacts in the field being by far the most *** the identification of pollen carried by pollinators allows uncovering interactions and increasing sample sizes,the methods used to build pollen-transport networks are variable and their effect on network structure remains *** understand how interaction sampling influences the structure of networks,we analyzed the pollen found on wild bees from eight communities across Mallorca Island and investigated the differences in pollen loads between bee body parts(scopa ***)and *** then assessed how these differences,as well as the uncovered interactions not detected in the field,influenced the structure of wild bee-plant *** identified a higher quantity and diversity of pollen in the scopa than in the rest of the female body,but these differences did not lead to differences in structure between plant-pollination(excluding scopa pollen)and bee-feeding interaction(including scopa pollen)***,networks built with pollen data were richer in plant species and interactions and showed lower modularity and specialization(H2'),and higher nestedness than visitation networks based on field *** interactions with plants were stronger compared to those of males,although not ***,females were more generalist(low d')and tended to be more central in interaction networks,indicating their more key role structuring pollination networks in comparison to *** study highlights the importance of palynological data to increase the resolution of networks,as well as to understand important ecological questions such as the differences between plant-pollination and bee-feeding interaction networks,and the role of sexes in pollination.

关键词： palynology pollen-transport networks pollination role of bee sexes sampling methodology visitation networks

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Tuning gelatin-based hydrogel towards bioadhesive ocular tissue engineering applications

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Bioactive Materials 2021年第11期6卷 3947-3961页

作者： Sina Sharifi Mohammad Mirazul Islam Hannah Sharifi Rakibul Islam Darrell Koza Felisa Reyes-Ortega David Alba-Molina Per H.Nilsson Claes H.Dohlman Tom Eirik Mollnes James Chodosh miguel gonzalez-andrades Massachusetts Eye and Ear and Schepens Eye Research Institute Department of OphthalmologyHarvard Medical SchoolBostonMAUSA Department of Immunology Oslo University HospitalRikshospitaletUniversity of OsloOsloNorway Department of Physical Sciences Eastern Connecticut State UniversityWillimanticCTUSA Linnaeus Center for Biomaterials Chemistry Linnaeus UniversityKalmarSweden Research Laboratory Nordland HospitalBodøNorway Centre of Molecular Inflammation Research Norwegian University of Science and TechnologyTrondheimNorway Maimonides Biomedical Research Institute of Cordoba(IMIBIC) Department of OphthalmologyReina Sofia University Hospital and University of CordobaCordobaSpain Faculty of Health Sciences K.G.Jebsen TRECUniversity of TromsøNorway

Gelatin based adhesives have been used in the last decades in different biomedical applications due to the excellent biocompatibility,easy processability,transparency,non-toxicity,and reasonable mechanical properties to mimic the extracellular matrix(ECM).Gelatin adhesives can be easily tuned to gain different viscoelastic and mechanical properties that facilitate its ocular *** herein grafted glycidyl methacrylate on the gelatin backbone with a simple chemical modification of the precursor,utilizing epoxide ring-opening reactions and visible *** chemical modification allows the obtaining of an elastic protein-based hydrogel(GELGYM)with excellent biomimetic properties,approaching those of the native *** can be modulated to be stretched up to 4 times its initial length and withstand high tensile stresses up to 1.95 MPa with compressive strains as high as 80%compared to Gelatin-methacryloyl(GeIMA),the most studied derivative of gelatin used as a *** is also highly biocompatible and supports cellular adhesion,proliferation,and migration in both 2 and 3-dimensional *** characteristics along with its super adhesion to biological tissues such as cornea,aorta,heart,muscle,kidney,liver,and spleen suggest widespread applications of this hydrogel in many biomedical areas such as transplantation,tissue adhesive,wound dressing,bioprinting,and drug and cell delivery.

关键词： Natural-based hydrogel Gelatin Biocompatible Biomimetic Bioadhesive Cornea

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Vertical Displacement Measurement in a Slow-Moving Sinkhole Using BOTDA

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Photonic Sensors 2024年第1期14卷 23-39页

作者： Pascual SEVILLANO Javier PRECIADO-GARBAYO Jorge SEVIL Francisco GUTIERREZ Juan JMARTiNEZ Sonia MARTiN-LOPEZ miguel gonzalez-HERRAEZ Aragon Institute of Engineering Research(I3A) Universidad de ZaragozaZaragoza 50018Spain Electronic Enginering and Communicaton Dpartment EINAUniversidad de ZaragzaZaragza 50018Spain Aragon Photonics Labs. Zaragoza 50009Spain Department of Earth Sciences Universidad de ZaragozaZaragoza 50009Spain Department of Electronics Escuela Politecnica SuperiorUniversidad de AlcalaMadrid 28805Spain

The effectiveness of monitoring and early-warning systems for ground deformation phenomena,such as sinkholes,depends on their ability to accurately resolve the ongoing ground displacement and detect the subtle deformation preceding catastrophic *** sinkholes with a slow subsidence rate and diffuse edges pose a significant challenge for subsidence monitoring due to the low deformation rates and limited lateral strain *** this work,we satisfactorily illustrate the practicality of the Brillouin optical time domain analysis(BOTDA)to measure the spatial-temporal patterns of the vertical displacement in such challenging slow-moving sagging *** assess the performance of the approach,we compare the strain recorded by the distributed optical fiber sensor with the vertical displacement measured by high-precision *** results show a good spatial correlation with the ability to identify the maximum subsidence *** is also a good temporal correlation with the detection of an acceleration phase in the subsidence associated with a flood event.

关键词： Distributed fiber optic sensing(DFOS) vertical displacement measurement slow subsidence rate sinkhole hazard early-warning system

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Thermo-electro-mechanical microstructural interdependences in conductive thermoplastics

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npj Computational Materials 2023年第1期9卷 955-965页

作者： Javier Crespo-miguel Sergio Lucarini Angel Arias Daniel Garcia-gonzalez Department of Continuum Mechanics and Structural Analysis Universidad Carlos III de MadridAvda.de la Universidad 3028911 LeganésMadridSpain Department of Civil and Environmental Engineering Imperial College of LondonSouth Kensington CampusLondon SW72AZUK

Additive manufacturing has enabled the design of thermoplastic components that provide structural support,electrical conductivity and heat generation modulated by mechanical *** mechanisms and interplays that govern the material response at the microstructural level remain,however,***,we develop an experimental method to characterise conductive filaments from a combined mechanical,electrical and thermal *** approach is used to unravel exciting material interplays of conductive polylactic *** overcome experimental limitations that prevent a complete microstructural analysis of the problem,we develop a full-field homogenisation framework and implement it for finite *** framework accounts for viscoplasticity,electrical and thermal conduction,convection and heat generation via Joule effect,as well as for the interdependences between *** experimental validation,the framework is applied to virtually optimise fabrication requirements to obtain desired properties in final products,i.e.,stiffer products,filaments with higher conductivities or with better sensing capabilities.

关键词： conductive electrical overcome

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Decoupled Photovoltaic Power Ramp-rate Calculation Method for Perturb and Observe Algorithms

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Journal of Modern Power Systems and Clean Energy 2022年第4期10卷 932-940页

作者： Jose miguel Riquelme-Dominguez Francisco M.gonzalez-Longatt Sergio Martinez Electrical Engineering Department Escuela Tecnica Superior de Ingenieros IndustrialesUniversidad Politecnica de Madrid28006 MadridSpain Department of Electrical Engineering Information Technology and CyberneticsUniversity of South-Eastern Norway3918 PorsgrunnNorway

As photovoltaic energy increasingly penetrates in power systems,transmission system operators have started to request its participation in providing ancillary *** of the demanded services is the power ramp-rate control(PRRC),which attempts to limit the power ramps produced by intermittent irradiance *** order to achieve the desired objective,solutions based on storage systems or modifying the maximum power point tracking(MPPT)in perturb and observe(P&O)algorithms are commonly *** starting point in PRRC is the determination of the instantaneous power ramprate,and different methods have been proposed in the literature for its ***,the accuracy and computational speed of existing procedures can be improved,which may be critical in situations with rapid irradiance *** this paper,a decoupled photovoltaic power ramp-rate calculation method is presented,in which the effect of variable irradiance and the P&O algorithm are computed *** proposed method has been theoretically demonstrated and tested through simulation and experimental *** results show that it can improve the previous methods in terms of accuracy and computation *** validation with hardware-inthe-loop demonstrates the suitability of the proposed method for real-time applications,even in presence of noisy measurements.

关键词： Hardware-in-the-loop maximum power point tracking perturb and observe photovoltaic power ramp-rate control ramp-rate calculation method

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Hybrid magnetorheological elastomers enable versatile soft actuators

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npj Computational Materials 2022年第1期8卷 1546-1559页

作者： miguel Angel Moreno-Mateos Mokarram Hossain Paul Steinmann Daniel Garcia-gonzalez Department of Continuum Mechanics and Structural Analysis Universidad Carlos III de MadridAvda.de la Universidad 3028911LeganésMadridSpain Zienkiewicz Centre for Computational Engineering Faculty of Science and EngineeringSwansea UniversitySA18ENSwanseaUK Institute of Applied Mechanics University of Erlangen-NurembergEgerland Str.5ErlangenGermany Glasgow Computational Engineering Centre School of EngineeringUniversity of GlasgowG128QQGlasgowUK

Recent advances in magnetorheological elastomers(MREs)have posed the question on whether the combination of both soft-and hard-magnetic particles may open new routes to design versatile multifunctional ***,we conceptualise ultra-soft hybrid MREs(≈1–10 kPa stiffness)combining experimental and computational ***,a comprehensive experimental characterisation is *** results unravel that the magneto-mechanical performance of hybrid MREs can be optimised by selecting an adequate mixing ratio between ***,a multi-physics computational framework provides insights into the synergistic magneto-mechanical interactions at the *** particles amplify the magnetisation and hard particles contribute to torsional *** numerical results suggest that the effective response of hybrid MREs emerges from these intricate ***,we uncover exciting possibilities to push the frontiers of MRE *** are demonstrated by simulating a bimorph beam that provides actuation flexibility either enhancing mechanical bending or material stiffening,depending on the magnetic stimulation.

关键词： versatile magneto enable

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基于计算缩放的光滑粒子水动力学方法模拟飞机油箱剧烈晃动问题

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Acta Mechanica Sinica 2023年第2期39卷 39-48页

作者： Calderon-Sanchez Javier Martinez-Carrascal Jon gonzalez Leo miguel CEHINAV Model Basin ETSI NavalesUniversidad Politécnica de MadridMadrid28040Spain

大型民用飞机的机翼设计用于承受从大气阵风到湍流到着陆冲击的各种载荷,机翼是需要进一步研究的重要结构.改进机翼设计的主要方法之一是分析晃动对承载液体的柔性机翼状结构动力学的阻尼效应.这将通过开发实验装置来实现,该装置将有助... 详细信息

大型民用飞机的机翼设计用于承受从大气阵风到湍流到着陆冲击的各种载荷,机翼是需要进一步研究的重要结构.改进机翼设计的主要方法之一是分析晃动对承载液体的柔性机翼状结构动力学的阻尼效应.这将通过开发实验装置来实现,该装置将有助于建立和再现涉及物理领域的数值模型.因此,本工作的目的是使用数值方法光滑粒子流体动力学(SPH)作为主要数值工具,分析晃动在降低飞机结构设计载荷方面的影响.本研究中的一个关键因素是对比例实验的需求,这是评估计算工具是否能够准确近似不同比例的注册测量值的必要步骤.为此,建立了一个垂直振动水槽的数值模型,该模型是一个完全耦合的流固耦合问题.该结构通过质量-弹簧-阻尼器系统建模,对于内部流体,使用δ-SPH方法.特别是,研究了两个开放性问题:第一个问题是,当储罐的初始加速度是标准重力值的十倍时,重力对阻尼和能量耗散现象的影响程度;第二种问题旨在确认,当根据量纲分析对问题参数进行缩放时,SPH方程正确地再现了缩放定律.

关键词： SPH Sloshing Gravity Computational scaling

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Artificial intelligence model validation before its application in clinical diagnosis assistance

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World Journal of Gastroenterology 2022年第5期28卷 602-604页

作者： Gustavo Jesus Vazquez-Zapien Monica Maribel Mata-Miranda Francisco Garibay-gonzalez miguel Sanchez-Brito Embryology Lab Escuela Militar de MedicinaCiudad de Mexico 11200CDMXMexico Cell&Tissue Biology Lab Escuela Militar de MedicinaCiudad de Mexico 11200CDMXMexico Department of Research Escuela Militar de MedicinaCiudad de Mexico 11200CDMXMexico Instituto Tecnológico de Zacatepec Industrial EngineeringTecNMZacatepec 62780MorelosMexico Instituto Tecnológico de Aguascalientes Computational SciencesTecNMAguascalientes 20256Mexico

The process of selecting an artificial intelligence(AI)model to assist clinical diagnosis of a particular pathology and its validation tests is relevant since the values of accuracy,sensitivity and specificity may not reflect the behavior of the method in a real ***,we provide helpful considerations to increase the success of using an AI model in clinical practice.

关键词： Artificial intelligence Diagnostic assistance Validation tests Leave-one-out cross-validation K-fold validation Hold-out validation

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